Mdid Lab Molecular Diagnostics more info http://www.mindlab-group.com/

1. Rapid detection
for life protection
MDID LAB
Molecular Diagnostics

2. Bacteria
Virus
Fungus
Parasites
Botulism
pneumonia
Urinarytractinfections
Tetanus
Gasgangrene
Endocarditis Dipheteria
Bronchitis
SalmonellaImpetigo
Cellulitis
Shigella
Listeriosis
Septicarthritis
Plague
Scarletfever
Puerperalfever
Syphilis
Osteomyelitis
Skin
Meningitis
Gastroenteritis Otitismedia
Malaria
Dengue
Measles
HIV
Hepatitis
Cholera
Sinusitis
Eyeinfections
Papillomavirus
Gonorrhoea
Brucellosis
Qfever
Sepsis
AfricanTrypanosomiasis
JapaneseEncephalitis
Leishmaniasis
StrepThroat
Tuberculosis
Gastritis
Legionnaires
Disease
Typhoid
fever
Clostridiumdifficile
HumanInfections
HUS
Necrotizing
TSS
Tinea
Herpes
Chagasdisease
Chickenpox
CMV
Epsteinbarr
giardiasis
mononucleosis
Parvorirus
Polio
Toxoplasmosis
Whoopingcough
mumps
Ascariasis
Tapeworm
Ebola
Rotavirus
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Human-Infections
Bacteria
Virus
Fungus
Parasites
Clostridium-difficile
PNEUMONIA
Urinarytract-infections
Infectious Diseases
Infectious diseases kill more people worldwide than any other single cause

3. Pneumonia
3 Million deaths / Year
> 40 Pathogens

4. PATIENT
DOCTOR
LABORATORY
RESULTS
Time-consuming microbiological diagnosis
3 days – 1 month
Sample culture
Isolation and identification
Antimicrobial resistance
Wait for growth
“The diagnostic is essentially clinical. Serological testing
normally takes 3 days while cultural exams, when possible, can
take at least 2-6 days” (MªLuz Araújo, infecciologist)
Infectious Diseases – The problem

5. Infectious Diseases – The problem
“Most of the times we don’t know what we are actually treating for”
(Carla Santos, infecciologist)
No pathogen directed
therapy applied
T Welte et al. Thorax 2012;67:71-79
Culture negative results

6. Infectious Diseases – The need
Faster microbiological results
Faster pathogen identification
Faster antimicrobial resistance detection
Higher sensitivity

7. Nuclei Acid
Extraction
(DNA/RNA)
RT-PCR
Biological Sample
Blood
Urine
Sputum
Cerebrospinal fluid
Biopsy
Superior microbiological identification
specific primers and probes
MDID Proprietary
Bacteria
Virus
Fungi
Parasites
Infectious Diseases – Our solution

8. Our solution– Direct benefits
Conventional
Diagnostics
MDID Lab
Time
Sample amount
Specificity
Simultaneous
antimicrobial resistance
Sensitivity
Pathogen detection
>98%
10 mL 0.5 mL
20%-80% >95%
3 DAYS – 1 MONTH 6-24H
Ó P
BACTERIA/FUNGI
1/test
bacteria/fungi/virus/
Parasites - up to 45/test
90%

9. MARKET
USA
1.1M Cases
Europe
1M Hospitalized
Pneumonia cases
Global Molecular Diagnostic Market
2013 Valued at 4.5 B USD
Source:marketwatch

10. NUCLEIC ACID AMPLIFICATION TECHNOLOGY
COMPETITORS

11. Proof-of-concept
• Patent submission
• Regulatory Issues
• Clinical validation
• R&D
• Primer/probe
development
2016 2017 2018
Business
development and
Regulatory
2009 2019
ROADMAP
Development of new diagnostic panels
License the use for international
diagnostic laboratories Exit strategy
2020
1st Diagnostic
Panel:
Pneumonia
infections

12. TEAM
Sandra Aguiar
PhD in Microbiology
General Management
Program
Postdoctoral researcher Postdoctoral researcher
PhD in Molecular Biology
Hospital Management
Specialization
Catarina Baptista

13. Thank You
Contact: mdidlab@gmail.com
MDID Lab