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Tumours of the larynx
Introduction  ,[object Object]
Benign tumours Pseudotumours Mesodermal tumours Ectodermal tumours
Ectodermal tumours Adenoma Neurilemmoma Paraganglioma Papilloma
Papilloma Single papilloma Multiple papillomas
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Single papilloma
Laryngeal papilloma Squamous papilloma of  the Lt. aryepiglottic fold
Multiple papillomas ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Multiple papillomas
Juvenile laryngeal papillomas
Juvenile papillomas Before and after removal
Adenoma  ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],Mesodermal tumours
Vascular neoplasms ,[object Object],[object Object],[object Object],[object Object],[object Object]
Chondroma ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Chondroma ,[object Object],Cricoid chondroma
[object Object],[object Object],[object Object],[object Object],Chondroma
Malignant  tumours
Introduction  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Incidence ,[object Object],[object Object]
[object Object],Classification 20% 10% 70%
Aetiology  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Symptoms   ,[object Object],[object Object],[object Object],[object Object],[object Object]
Symptoms ,[object Object],[object Object],[object Object]
Examination and diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
History   Small lesion + long history slowly growing lesion Massive cancer  + short history Aggressive lesion poor outlook
Cancer can coexists or supervene in  leucoplakia, chronic laryngitis & TB Leucoplakia Chronic laryngitis
Vocal Cord Leukoplakia :    This is a condition caused by chronic irritation which results in abnormal growth of the top layer of the skin lining the vocal cords.It is often seen in smokers and is considered a pre-cancerous condition. 
Examination of the larynx ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
subglottis   ventricle posterior surface of epiglottis   Difficult areas to be seen
Examination of the neck ,[object Object],[object Object],[object Object],[object Object]
Incidence of nodal metastasis  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
General examination ,[object Object],[object Object]
Radiological investigations ,[object Object],[object Object],X-ray  CT scan MRI
X-ray  Supraglottic tumour Tomography AP Lateral
Axial CT shows loss of pre-epiglottic fat by carcinomatous infiltrarion CT scan
Axial CT scan showing a soft tissue mass with several  punctuate calcifications (Chondrosarcoma) CT scan
Epiglotic tumor ( laryngeal Ca. supraglotic type ) MRI
MRI Axial T1 image showing large supraglottic Ca extending to retropharyngeal space Abutting the Rt. carotid artery (curved open arrow) Destruction of the Rt. thyroid ala (short open arrow) Destruction of the Rt. arytenoid (short solid arrow)
MRI Sagittal T2 image of supraglottic Ca Extension involves the epiglottis :E Loss of normal pr-epiglottic fat plane: solid arrows Tongue base involvement : open arrow
Axial MRI showing tumour of the Rt. VC MRI
MRI Coronal view of MRI showing subglottic extension
Sagittal view showing transglottic tumour MRI
Clinical investigations ,[object Object],[object Object],[object Object],[object Object]
Histological examination   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pathology ,[object Object],[object Object]
Spread of laryngeal carcinoma
Glottic Ca Origin the free margin of the vocal cords Invasion & extension ,[object Object],[object Object],[object Object],[object Object],[object Object]
Cancer of the Lt true vocal cord
glottic CA
cancer involving the  true vocal cords  and  arytenoid .  The cancer also extends onto the  supraglottis
[object Object],Glottic Ca
Supraglottic Ca ,[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],Supraglottic Ca Invasion
Supraglottic Ca Epiglottic tumpur Tumour of Lt aryepiglottic fold Tumour of   Rt false cord
[object Object],[object Object],[object Object],[object Object],Subglottic Ca
Subglottic Ca
Lymph node involvement ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],Distant metastasis
TNM  classificaiton T   :  Primary tumour N:  Nodal deposits M:  Metastasis
T   :  Primary tumour TX T0 Tis Primary tumour can not be assesed No evidence of primary tumour Carcinoma in situ
T   : Primary tumour  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
T1a Rt.VC Ca with normal mobility Glottic
T1b Limited mobile both cords Glottic
Glottic ,[object Object],[object Object],large tumor on the left  true vocal cord and anterior  false vocal cords  (T2 Cancer)
cancer involving the  true vocal cords  and  arytenoid . The cancer also extends onto the  supraglottis   T2 Glottic
Glottic ,[object Object],[object Object],Lt VC Ca with fixation
Subglottic ,[object Object],T1 T1 subglottis
Subglottic ,[object Object],T2 Subglottic tumour extends to glottis
Subglottic T3 T4 cord fixation extends beyond the larynx
Lt false cord tumour Supraglottic T1 limited / mobile cords
T2 Supraglottic Ca of the Rt. aryepiglottic fold Extends to glottis Moblie cords
[object Object],extends beyond the larynx   Supraglottic T3 T4 Ca of the Lt. arytenoid
N : Nodal deposits ,[object Object],[object Object],[object Object],NO LN deposits N0
M : Metastasis ,[object Object],[object Object]
Staging ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment
Rehabilitation  Treatment curative  No treatment Palliation
No treatment ,[object Object],[object Object],[object Object],[object Object]
Palliation  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Tracheostomy  ,[object Object],[object Object]
Radiotherapy ,[object Object],[object Object],[object Object]
Curative treatment Radiotherapy Surgery Chemotherapy
[object Object],[object Object],[object Object],Radiotherapy
CA larynx for radiotherapy
Surgery Microendolaryngeal and laser surgery Excisional surgery
Microendolaryngeal and laser surgery ,[object Object],[object Object],[object Object]
Microendolaryngeal and laser surgery
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Excisional surgery
Total laryngectomy Removed specimen
Thank you

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