The document provides an overview of immunology topics covered in a course, including the immune system and disease, immunopathology, and therapeutic applications. The course covers basics of the immune system, innate and adaptive immunity, cells and molecules of the immune system, and applications like immunization, transplantation, and immunotherapy. Immunopathology topics include immunodeficiency, autoimmunity, hypersensitivity, and malignancies of the immune system. Therapeutic applications focus on immunization, immunomodulation, transplantation, immunosuppression, and replacement therapies.

2. Understanding Immunology Dr. Ahmed Elshebiny , MD Lecturer of Internal Medicine Faculty of Medicine, Menoufyia University Former Clinical Research Fellow, Joslin Diabetes Center, Harvard University

5. Immunity

10. Innate Adaptive Immunity Cellular Humoral Cellular Humoral Let us see this video about immunity

18. Cells of the immune system T-cell development

19. Cells of the immune system

24. Phagocytosis

36. Immunoglobulins

37. Classes of Immunoglobulines

38. Immunoglobulins & age

39. Plasma protein electrophoresis

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51. Understanding Immunology(2) Immunopathology

52. Immunodeficiency Immunopathology Autoimmunity Hypersensitivity Lymphoproliferative Diseases

53. Immunodeficiency

56. Immune response to HIV

57. CD4 depletion along the course of HIV

59. Complement deficiencies Immunodeficiency B-cell disorders Neutrophil Disorders T-cell disorders Combined B and T-cell disorders

61. Lymphocyte disorders

66. Clinical history

68. 2- Autoimmunity

70. Type-1 diabetes

74. Transplacental transfer

78. Hodgkin's disease

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85. Understanding Immunology (3) Therapeutic applications

86. Immunization Therapeutic applications of Immunology Immunomodulation Transplantation Immunosupression Anti-allergic Replacement

97. MHC I & II CD4 TH cells CD8 TC cells Recognized by Presentation of Ag to TH cells which secrete cytokines Presentation of Ag to TC cells leading to elimination of tumor or infected host cell Functions Macrophages, B-cells, Dentritic cells, langerhans cells of skin and activated T cells All nucleated somatic cells Found on HLA-DP, HLA-DQ, HLA-DR HLA-A, HLA-B, HLA-C Nomenclature MHC Class II MHC Class I

106. Nomenclature of monoclonal abs toxin as target -tox(a)- nervous system -neu(r)- miscellaneous tumor -tu(m)- prostate tumor -pr(o)- ovarian tumor -go(v)- testicular tumor -go(t)- mammary tumor -ma(r)- melanoma -me(l)- colonic tumor -co(l)- rat/murine hybrid -axo- interleukin -ki(n)- humanized -zu- musculoskeletal -mu(l)- chimeric -xi- cardiovascular -ci(r)- primate -i- infectious lesions -le(s)- hamster -e- immune -li(m)- rat -a- bacterial -ba(c)- mouse -o- viral -vi(r)- -mab human -u- bone -o(s)- variable Suffix Source Target Prefix

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