Stem cells

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Kashif Shamaun

Introduction to Stem Cells with basic concept of stem cells in Islam and Christianity.

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Stem cells Undifferentiated cells capable of self-renew and to differentiate into different cell types or tissues during embryonic development and throughout adulthood. Have possibility to become a specialised cell. Have the ability to divide continuously and develop into various other kinds of cells. Have immune potential and can help to treat a wide range of medical problems. Discovery of stem cells lead to a whole new branch of medicine known as Regenerative medicine.

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هذا الكشف يشرح كيف أن نهايات الكرموسومات يتم حمايتها بالتلومير وكيف انه يتم بنائها بإنزيم التيلوميراز لو قصرت التيلوميرات في الطول تشيخ الخلية بالعكس لو زادت نشاط إنزيم التيلوميراز يحافظ على طول التيلوميرات وموت الخلية يتأخر وهذه الحالة تكون في حالات الاصابه بالسرطان والتي فيها تكون حياة الخلية أبديه بعض الأمراض الوراثيه على العكس تتميز بنقص نشاط إنزيم التيلوميراز مما يتسبب في موت الخلية

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The ISSCR is an independent, nonprofit organization providing a global forum for stem cell research and regenerative medicine. Stem Cell Facts What are stem cells? Stem cells are the foundation cells for every organ and tissue in our bodies. The highly specialized cells that make up these tissues originally came from an initial pool of stem cells formed shortly after fertilization. Throughout our lives, we continue to rely on stem cells to replace injured tissues and cells that are lost every day, such as those in our skin, hair, blood and the lining of our gut. Stem cells have two key properties: 1) the ability to self-renew, dividing in a way that makes copies of themselves, and 2) the ability to differentiate, giving rise to the mature types of cells that make up our organs and tissues. Tissue-specific stem cells Tissue-specific stem cells, which are sometimes referred to as “adult” or “somatic” stem cells, are already somewhat specialized and can produce some or all of the mature cell types found within the particular tissue or organ in which they reside. Because of their ability to generate multiple, organ-specific, cell types, they are described as “multipotent.” For example, stem cells found within the adult brain are capable of making neurons and two types of glial cells, astrocytes and oligodendrocytes. Tissue-specific stem cells have been found in several organs that need to continuously replenish themselves, such as the blood, skin and gut and have even been found in other, less regenerative, organs such as the brain. These types of stem cells represent a very small population and are often buried deep within a given tissue, making them difficult to identify, isolate and grow in a laboratory setting. Neuron – Dr. Gerry Shaw, EnCor Biotechnology Inc. Astrocyte – Abcam Inc. Oligodendrocyte – Dhaunchak and Nave (2007). Proc Natl Acad Sci USA 104:17813-8 www.isscr.org Embryonic stem cells Embryonic stem cells have been derived from a variety of species, including humans, and are described as “pluripotent,” meaning that they can generate all the different types of cells in the body. Embryonic stem cells can be obtained from the blastocyst, a very early stage of development that consists of a mostly hollow ball of approximately 150-200 cells and is barely visible to the naked eye. At this stage, there are no organs, not even blood, just an “inner cell mass” from which embryonic stem cells can be obtained. Human embryonic stem cells are derived primarily from blastocysts that were created by in vitro fertilization (IVF) for assisted reproduction but were no longer needed. The fertilized egg and the cells that immediately arise in the first few divisions are “totipotent.” This means that, under the right conditions, they can generate a viable embryo (including support tissues such as the placenta). Within a matter of days, however, these cells transition to become pluripote ...

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