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The wonderful world of cells!



A fascinating insight into the world of
cells, who discovered them, the
different types and what they are
made up of.
Microscopes
    Light microscope         Electron microscope
Uses light rays           Uses electron ‘beams’
Magnification – x2000     Magnification – x500,000
Resolving power – 200nm Resolving power – 1nm
Focused by glass lenses   Focused by electromagnets
Specimens can be living or Specimens must be dead
dead
Small, portable and       Large, static and very
relatively inexpensive    expensive
Microscopes
   Magnification – to make an image appear bigger
   To calculate the magnifying power of a
    microscope:

eye piece lens magnification X objective lens

   Resolution – the minimum distance between 2
    points at which they are still visible as 2 separate
    points
Robert Hooke
He looked at cork
cells under a
microscope and
used the term
‘cell’. The holes
that he observed
where once filled
with living material
(cytoplasm)
Robert Hooke’s cells
Theodor Schwann
Matthias Schleiden
Cell theory with the cell
Schwann and Schleiden came up
  theory.
They proposed that all plants and animals
  were made up of cells and that cells were
  the basic units of life
Another scientist, Rudolf Virchow discovered
  that new cells can only arise from the
  division of pre-existing ones.
Prokaryotic and Eukaryotic cells
   No true nucleus                Distinct nucleus
   Few organelles except for       surrounded by a nuclear
                                    envelope
    small ribosomes
                                   Many membrane bound
   Single strand of genetic        organelles
    material free in the cell      Genetic material is stored
   Simple structure                in the nucleus
   Small in size                  Highly organized to carry
   Include bacteria and            out complex functions
    blue/green algae               Large in size
                                   Include plants, animals
                                    and fungi
Eukaryotic cell
Animal cells: these are cheek cells as
seen with a compound microscope,
compare these cells to the next ones
seen through an electron microscope.
Plant and animal cells
   Cellulose cell wall        No cell wall
   Chloroplasts               No chloroplasts
   Large permanent            Small, temporary
    vacuole with cell sap       vacuoles
   No centrioles              Centrioles present
   Starch grains for          Glycogen granules
    storage                     for storage
Plant cell
Animal cell
Cytoplasm

   Watery, jelly-like material

   Contains many substances for metabolism

   The other organelles are suspended in it
Cellulose cell wall
   Many cellulose fibers glued together
   Strong to resist expansion of the cell as
    water enters – this supports the cell
   Provides mechanical strength to the cell
   Freely permeable
Vacuole
   Large permanent vacuole in plant cells is
    called a central vacuole. It contains cell
    sap, a solution of sugar and minerals.
   They are food stores
   They accumulate waste products
   Some contain pigments to give color
   Vacuoles in animal cells are small and
    temporary
Nucleus
   Largest cell organelle
   Surrounded by a double membrane that
    allows materials to pass in and out
   Contains genetic material (DNA) which is
    used to make proteins
   Controls the metabolic activity of the cell
Nucleolus
   Found in the nucleus
   Dense, spherical structure
   Contains RNA for the production of
    ribosomes
Ribosomes

   Small, dense organelles
   Can be free in the cytoplasm or attached to
    rough endoplasmic reticulum
   They are made in the nucleolus
   They are the site of protein synthesis
Endoplasmic reticulum
   Complex system of double membranes with
    fluid-filled sacs in between called cisternae
   Connected with the nuclear membrane and the
    cell membrane
   It collects, stores and distributes materials
   Rough endoplasmic reticulum has ribosomes on
    it. It packages and transports proteins made by
    ribosomes
   Smooth endoplasmic reticulum is the site of lipid
    (fat) synthesis.
Golgi complex
   Also known as golgi body or apparatus
   Made from small pieces of rough ER
    pinched off at the end to form vesicles
    which fuse together
   Site of protein modification
   Vesicles pinch off at the ends to carry the
    new chemicals away (some vesicles
    become lysosomes)
Lysosomes
   Small vesicles formed when pieces of the golgi
    body pinch off
   Contain hydrolytic enzymes that can digest cell
    material
   They destroy worn out organelles
   They can destroy material brought into the cell
    (e.g. bacteria)
   They can release enzymes out of the cell to digest
    other cells
   They can cause the cell to self destruct
Mitochondria
   Has a double membrane. The outer one
    controls entry of materials and the inner
    one has many folds called cristae
   Has a matrix containing DNA, ribosomes
    and enzymes
   Site of aerobic respiration
   The more active the cell, the more
    mitochondria it has
Chloroplasts
   Found in plants cells that carry out
    photosynthesis
   They are the site of photosynthesis
   They have a double membrane filled with fluid
    (stroma) where the photosynthesis reactions take
    place
   The stroma contains piles of flattened scas
    (grana) where chlorophyll is found and light is
    absorbed
Cytoskeleton
   This is a network of fibrous proteins
   It allows movement and gives the cell
    shape and support
   It is made up of microtubules and
    microfilaments
Centrioles
   These are 2 short bundles of microtubules
    positioned at right angles to each other.
   They are found just outside the nucleus in
    animal cells
   During cell division, they move to opposite
    ends of the cell and produce the spindle
Flagella


   Also made up of microtubules

   Often used to help cells move (e.g. sperm)
Cell membrane
   Made up of a bilayer of phospholipids that
    allows some materials through but not
    others (semi-permeable)
   Contains proteins that can act as pores,
    carriers or be involved in cell recognition
   The main function is to regulate the
    movement of molecules and ions
Cell membrane structure
   Made up of a bilayer of phospholipids.
    They have a polar end (water liking) and a
    non-polar end (water hating)

   Protein carrier molecules are found
    embedded in the cell membrane; these
    molecules form specific bridges allowing
    specific molecules to pass through
Transport across membranes
   The cell membrane is thin and provides a large
    surface area for diffusion to occur
   Diffusion is the movement of molecules or ions
    from a region of high concentration to a region of
    low concentration until they are spread out evenly
    (down a concentration gradient)
   A big difference in concentration, an increase in
    temperature, small molecules and a short
    diffusion distance makes the rate of diffusion
    faster
Facilitated diffusion
   This allows faster movement
   It involves the use of proteins to assist (facilitate)
    diffusion
   Specific channel proteins form pores for specific
    molecules
   Carrier molecules bind to specific molecules,
    change shape and deliver the molecule to the
    other side of the membrane
Osmosis
   This is the diffusion of water molecules
   They move from where they are in a high
    concentration (a dilute solution) to where
    they are in a low concentration (a
    concentrated solution)
Osmosis in plant cells
   As water enters a plant cell, the cell starts to
    swell. The cell wall starts to resist the stretching
    which creates pressure
   When no more water can enter the cell, it is said
    to be TURGID. This provides strength and
    support to the cell
   If water leaves a cell, the membrane can pull
    away from the cell wall. This causes a plant to
    wilt
Different solutions
   Solution – a mixture of 2 or more substances
   Solvent – the liquid that a substance dissolves in
   Solute – the substance that dissolves in a solvent
   Hypotonic – a weak solution: weaker in solute
    concentration than cell
   Hypertonic – a strong solution: stronger in solute
    concentration than cell
   Isotonic – a solution with the same concentration
    as cell.
Active transport
   Moving molecules
    against a
    concentration gradient
    (from low to high
    concentration)
   It requires special
    carrier proteins called
    membrane pumps
   It uses energy in the
    form of ATP
Endocytosis and exocytosis
   For molecules too large to pass through the
    membrane
   Endocytosis – taking materials into the cell by
    closing the cell membrane around it to form a
    vesicle (There are 2 types, pincytosis and
    phagocytosis)
   Exocytosis – material in vesicles in the cell fuse
    with the cell membrane and are released
Wonderful world of cells

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Wonderful world of cells

  • 1. The wonderful world of cells! A fascinating insight into the world of cells, who discovered them, the different types and what they are made up of.
  • 2. Microscopes Light microscope Electron microscope Uses light rays Uses electron ‘beams’ Magnification – x2000 Magnification – x500,000 Resolving power – 200nm Resolving power – 1nm Focused by glass lenses Focused by electromagnets Specimens can be living or Specimens must be dead dead Small, portable and Large, static and very relatively inexpensive expensive
  • 3. Microscopes  Magnification – to make an image appear bigger  To calculate the magnifying power of a microscope: eye piece lens magnification X objective lens  Resolution – the minimum distance between 2 points at which they are still visible as 2 separate points
  • 4. Robert Hooke He looked at cork cells under a microscope and used the term ‘cell’. The holes that he observed where once filled with living material (cytoplasm)
  • 8. Cell theory with the cell Schwann and Schleiden came up theory. They proposed that all plants and animals were made up of cells and that cells were the basic units of life Another scientist, Rudolf Virchow discovered that new cells can only arise from the division of pre-existing ones.
  • 9. Prokaryotic and Eukaryotic cells  No true nucleus  Distinct nucleus  Few organelles except for surrounded by a nuclear envelope small ribosomes  Many membrane bound  Single strand of genetic organelles material free in the cell  Genetic material is stored  Simple structure in the nucleus  Small in size  Highly organized to carry  Include bacteria and out complex functions blue/green algae  Large in size  Include plants, animals and fungi
  • 10.
  • 11.
  • 13. Animal cells: these are cheek cells as seen with a compound microscope, compare these cells to the next ones seen through an electron microscope.
  • 14.
  • 15. Plant and animal cells  Cellulose cell wall  No cell wall  Chloroplasts  No chloroplasts  Large permanent  Small, temporary vacuole with cell sap vacuoles  No centrioles  Centrioles present  Starch grains for  Glycogen granules storage for storage
  • 18. Cytoplasm  Watery, jelly-like material  Contains many substances for metabolism  The other organelles are suspended in it
  • 19. Cellulose cell wall  Many cellulose fibers glued together  Strong to resist expansion of the cell as water enters – this supports the cell  Provides mechanical strength to the cell  Freely permeable
  • 20. Vacuole  Large permanent vacuole in plant cells is called a central vacuole. It contains cell sap, a solution of sugar and minerals.  They are food stores  They accumulate waste products  Some contain pigments to give color  Vacuoles in animal cells are small and temporary
  • 21. Nucleus  Largest cell organelle  Surrounded by a double membrane that allows materials to pass in and out  Contains genetic material (DNA) which is used to make proteins  Controls the metabolic activity of the cell
  • 22. Nucleolus  Found in the nucleus  Dense, spherical structure  Contains RNA for the production of ribosomes
  • 23. Ribosomes  Small, dense organelles  Can be free in the cytoplasm or attached to rough endoplasmic reticulum  They are made in the nucleolus  They are the site of protein synthesis
  • 24. Endoplasmic reticulum  Complex system of double membranes with fluid-filled sacs in between called cisternae  Connected with the nuclear membrane and the cell membrane  It collects, stores and distributes materials  Rough endoplasmic reticulum has ribosomes on it. It packages and transports proteins made by ribosomes  Smooth endoplasmic reticulum is the site of lipid (fat) synthesis.
  • 25.
  • 26. Golgi complex  Also known as golgi body or apparatus  Made from small pieces of rough ER pinched off at the end to form vesicles which fuse together  Site of protein modification  Vesicles pinch off at the ends to carry the new chemicals away (some vesicles become lysosomes)
  • 27. Lysosomes  Small vesicles formed when pieces of the golgi body pinch off  Contain hydrolytic enzymes that can digest cell material  They destroy worn out organelles  They can destroy material brought into the cell (e.g. bacteria)  They can release enzymes out of the cell to digest other cells  They can cause the cell to self destruct
  • 28. Mitochondria  Has a double membrane. The outer one controls entry of materials and the inner one has many folds called cristae  Has a matrix containing DNA, ribosomes and enzymes  Site of aerobic respiration  The more active the cell, the more mitochondria it has
  • 29. Chloroplasts  Found in plants cells that carry out photosynthesis  They are the site of photosynthesis  They have a double membrane filled with fluid (stroma) where the photosynthesis reactions take place  The stroma contains piles of flattened scas (grana) where chlorophyll is found and light is absorbed
  • 30. Cytoskeleton  This is a network of fibrous proteins  It allows movement and gives the cell shape and support  It is made up of microtubules and microfilaments
  • 31. Centrioles  These are 2 short bundles of microtubules positioned at right angles to each other.  They are found just outside the nucleus in animal cells  During cell division, they move to opposite ends of the cell and produce the spindle
  • 32. Flagella  Also made up of microtubules  Often used to help cells move (e.g. sperm)
  • 33. Cell membrane  Made up of a bilayer of phospholipids that allows some materials through but not others (semi-permeable)  Contains proteins that can act as pores, carriers or be involved in cell recognition  The main function is to regulate the movement of molecules and ions
  • 34.
  • 35. Cell membrane structure  Made up of a bilayer of phospholipids. They have a polar end (water liking) and a non-polar end (water hating)  Protein carrier molecules are found embedded in the cell membrane; these molecules form specific bridges allowing specific molecules to pass through
  • 36. Transport across membranes  The cell membrane is thin and provides a large surface area for diffusion to occur  Diffusion is the movement of molecules or ions from a region of high concentration to a region of low concentration until they are spread out evenly (down a concentration gradient)  A big difference in concentration, an increase in temperature, small molecules and a short diffusion distance makes the rate of diffusion faster
  • 37.
  • 38. Facilitated diffusion  This allows faster movement  It involves the use of proteins to assist (facilitate) diffusion  Specific channel proteins form pores for specific molecules  Carrier molecules bind to specific molecules, change shape and deliver the molecule to the other side of the membrane
  • 39.
  • 40. Osmosis  This is the diffusion of water molecules  They move from where they are in a high concentration (a dilute solution) to where they are in a low concentration (a concentrated solution)
  • 41. Osmosis in plant cells  As water enters a plant cell, the cell starts to swell. The cell wall starts to resist the stretching which creates pressure  When no more water can enter the cell, it is said to be TURGID. This provides strength and support to the cell  If water leaves a cell, the membrane can pull away from the cell wall. This causes a plant to wilt
  • 42.
  • 43. Different solutions  Solution – a mixture of 2 or more substances  Solvent – the liquid that a substance dissolves in  Solute – the substance that dissolves in a solvent  Hypotonic – a weak solution: weaker in solute concentration than cell  Hypertonic – a strong solution: stronger in solute concentration than cell  Isotonic – a solution with the same concentration as cell.
  • 44.
  • 45. Active transport  Moving molecules against a concentration gradient (from low to high concentration)  It requires special carrier proteins called membrane pumps  It uses energy in the form of ATP
  • 46. Endocytosis and exocytosis  For molecules too large to pass through the membrane  Endocytosis – taking materials into the cell by closing the cell membrane around it to form a vesicle (There are 2 types, pincytosis and phagocytosis)  Exocytosis – material in vesicles in the cell fuse with the cell membrane and are released