Its rapid onset and severity of symptoms makes prompt and effective diagnosis and treatment nearly impossible. For these reasons the meningococcal disease space is dominated by vaccines. Currently, tetravalent conjugate vaccines, such as Sanofis Menactra and Novartis Menveo, account for the vast majority of global sales, with the US adolescent market being the key target segment. GlobalData expects growth in the meningococcal vaccines market to be primarily driven by the launch of serotype B vaccines, which address a critical unmet need in the treatment landscape. Vaccines that better protect infants and/or provide a longer duration of immunity also have an opportunity to seize market share during 2012-2022

1. PharmaPoint: Meningococcal Vaccines - Italy Drug Forecast and Market Analysis to 2022
GlobalData has released its new Country report, PharmaPoint: Meningococcal Vaccines Italy Drug Forecast
and Market Analysis to 2022. Meningococcal disease is an acute infection caused by the gram-negative
bacterium Neisseria meningitidis. Its rapid onset and severity of symptoms makes prompt and effective
diagnosis and treatment nearly impossible. For these reasons the meningococcal disease space is dominated by
vaccines. Currently, tetravalent conjugate vaccines, such as Sanofis Menactra and Novartis Menveo, account
for the vast majority of global sales, with the US adolescent market being the key target segment. GlobalData
expects growth in the meningococcal vaccines market to be primarily driven by the launch of serotype B
vaccines, which address a critical unmet need in the treatment landscape. Vaccines that better protect infants
and/or provide a longer duration of immunity also have an opportunity to seize market share during
2012-2022.
Total sales in this segment of the market will decline slightly due to a population decrease in the targeted age
group of 1224 months of age. GlobalData predicts that relative patient share for the three MenC conjugate
vaccines will remain unchanged for the duration of the forecast period because Nuron Biotechs Meningitec,
Novartis Menjugate, and Baxters NeisVac-C possess nearly identical clinical profiles and price points. The
MenC conjugate patient share is largely determined by prescriber preference in Italy and therefore is not
expected to change drastically during the forecast period.
Scope
Overview of Meningococcal Vaccines including epidemiology, etiology, symptoms, diagnosis, pathology
and treatment guidelines as well as an overview on the competitive landscape. Detailed information on the key
drugs in Italy including product description, safety and efficacy profiles as well as a SWOT analysis. Sales
forecast for the top drugs in Italy from 2012-2022. Analysis of the impact of key events as well the drivers and
restraints affecting Italy Meningococcal Vaccines market.
Reasons to buy
Understand and capitalize by identifying products that are most likely to ensure a robust return Stay ahead of
the competition by understanding the changing competitive landscape for Meningococcal Vaccines Effectively
plan your M&A and partnership strategies by identifying drugs with the most promising sales potential Make
more informed business decisions from insightful and in-depth analysis of drug performance Obtain sales
forecast for drugs from 2012-2022 in Italy
table Of Contents
1 Table Of Contents 1
1.1 List Of Tables 3
1.2 List Of Figures 3
2 Executve Summary 4
PharmaPoint: Meningococcal Vaccines - Italy Drug Forecast and Market Analysis to 2022

2. 2.1 Sales For Meningococcal Vaccine In Italy 4
2.2 What Do The Physicians Think? 5
3 Introduction 6
3.1 Catalyst 6
3.2 Related Reports 7
3.3 Upcoming Related Reports 9
4 Disease Overview 9
4.1 Etiology And Pathophysiology 10
4.1.1 Etiology 10
4.1.2 Pathophysiology 11
4.2 Symptoms 12
4.3 Prognosis 13
5 Disease Management 13
5.1 Meningococcal Immunization Policy 14
5.2 Italy 15
5.2.1 Meningococcal Immunization Recommendations And Policies 15
5.2.2 Clinical Practice 16
6 Competitive Assessment 16
6.1 Overview 16
6.2 Strategic Competitor Assessment 16
6.3 Product Profiles Major Brands 18
6.3.1 Menveo 18
6.3.2 Nimenrix 22
6.3.3 Meningitec 24
6.3.4 Menjugate 26
6.3.5 Neisvac-c 28
6.3.6 Bexsero 31
7 Opportunity And Unmet Need 33
7.1 Overview 33
7.2 Unmet Needs 34
7.2.1 Unmet Need: Protection Against Serogroup B Disease 34
7.2.2 Unmet Need: A Pentavalent (menabcwy) Vaccine 34
7.2.3 Unmet Need: More Cost-effective Vaccines 35
PharmaPoint: Meningococcal Vaccines - Italy Drug Forecast and Market Analysis to 2022

3. 7.2.4 Unmet Need: Improved Duration Of Immunity In Children And Adolescents 36
7.2.5 Unmet Need: Immunogenic Infant Vaccines 37
7.2.6 Unmet Need: Improved Vaccination Coverage Rates 38
7.2.7 Unmet Need: Increased Patient Awareness And Education 39
7.3 Unmet Needs Gap Analysis 40
7.4 Opportunities 41
7.4.1 Opportunity: Broadening Serogroup Protection With New And Existing Antigen Combinations 41
7.4.2 Opportunity: Improving Immune Response Duration With Adjuvants 42
7.4.3 Opportunity: Developing More Cost-effective Vaccines By Partnering With Manufacturers In Emerging
Markets 43
8 Pipeline Assessment 43
8.1 Overview 43
8.2 Promising Vaccines In Clinical Development 43
8.2.1 Mnb Rlp2086 47
8.3 Promising Vaccines In Early Clinical Development 51
8.3.1 Meninge Acyw Conj. 51
8.3.2 Menabcwy 55
8.3.3 Menc Conjugate 57
8.3.4 Heptavalent Dtp-hib-hepb-ipv-menc 60
9 Market Outlook 62
9.1 Italy 62
9.1.1 Forecast 62
9.1.2 Key Events 65
9.1.3 Drivers And Barriers 66
10 Appendix 68
10.1 Bibliography 68
10.2 Abbreviations 78
10.3 Methodology 81
10.4 Forecasting Methodology 81
10.4.1 Vaccine Coverage 82
10.4.2 Vaccine Approval Vs. Routine Schedule Inclusion 82
10.4.3 Vaccines Included 83
10.4.4 Key Launch Dates 84
10.4.5 General Pricing Assumptions 85
10.4.6 Individual Vaccine Assumptions 86
10.4.7 Pricing Of Pipeline Agents 91
10.5 Physicians And Specialists Included In This Study 92
PharmaPoint: Meningococcal Vaccines - Italy Drug Forecast and Market Analysis to 2022

4. 10.6 About The Authors 95
10.6.1 Authors 95
10.6.2 Reviewers 95
10.6.3 Global Head Of Healthcare 95
10.7 About Globaldata 96
10.8 Contact Us 96
10.9 Disclaimer 96
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PharmaPoint: Meningococcal Vaccines - Italy Drug Forecast and Market Analysis to 2022