How do you know if you need to be tested for gluten sensitivity? If you're breathing. We are all at risk for the emerging syndrome called Non-Celiac Gluten Sensitivity (NCGS). Even if you have been tested in the past for celiac disease, because of the limited ability of tests routinely used in clinical practice, you may still suffer from gluten mediated symptoms and conditions. Moreover, NCGS is frequently missed because it often shows up as extra-intestinal symptoms such as brain fog, depression, anxiety, pain, and headaches. Most importantly, newer generation testing technologies are finally sensitive enough to determine if your historically hard to diagnose symptoms might actually turn out to be due gluten and/or other dietary toxins. One such test, and the one we use most often at Health Remedies, is the Cyrex Array 3. Check, check, check it out.

1. Sensitivity to
Do You Need
to be
(Re)Tested?
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2. Probably.
Here’s why(in
case you’ve
missed the
news) -
Gluten
sensitivity/intolerance
(Non-Celiac Gluten
Sensitivity ((NCGS))) has
been associated with many
symptoms and conditions.

3. Non-Celiac Gluten Sensitivity
(NCGS)
• An emerging
syndrome in people
who have tested
negative for celiac
disease and wheat
allergy and who have
symptoms that are
evoked by ingestion
of gluten.
Effect of gluten free diet on immune response to gliadin in patients with non-celiac gluten
sensitivity. Caio G, Volta U, Tovoli F, De Giorgio R. BMC Gastroenterol. 2014 Feb 13;14(1):26.

4. Non-Celiac Gluten Sensitivity (NCGS)
• NCGS is characterized by gastro-intestinal
(GI)symptoms as well as symptoms that affect
other parts of your body and brain:
GI Symptoms
• GERD
• Irritable bowel
syndrome (IBS)
• Bloating
• Cramping
• Constipation
• Diarrhea
Systemic Symptoms
• “Fog brain”
• Headaches
• Fatigue
• Depression
• Anxiety
• Pain
• Eczema/rash
Effect of gluten free diet on immune response to gliadin in patients with non-celiac gluten
sensitivity. Caio G, Volta U, Tovoli F, De Giorgio R. BMC Gastroenterol. 2014 Feb 13;14(1):26.

5. Moreover, gluten has been implicated
in the rise of Diseases
of Civilization.

7. The Background
• Chronic degenerative conditions (Diseases
of Civilization – DOCs) are on the rise and
have overtaken infections as the major
source of death and illness in the world.
• This epidemiological transition is due, at
least in part, to environmental changes that
have increased the disease liability of
genetic profiles that were previously
benign.
Cordain L, Eaton SB, Sebastian A, Mann N, Lindeberg S, Watkins BA, O'Keefe JH, Brand-Miller J.. Am J Clin
Nutr. 2005 Feb;81(2):341-54. Raison CL, Lowry CA, Rook GA. Arch Gen Psychiatry. 2010 Dec;67(12):1211-24.

8. One of these
environmental
changes is

9. To Review:
Tight Junction (TJ) Disassembly
(“Leaky Gut Syndrome”)
leads to disruption of gut lining
allowing dietary and environmental
toxins to leak into your body.
(and other
dietary
compounds)
Increased Immune Surveillance
mistakes food for foreign invaders.
Antibodies,
Autoimmunity,
and Oxidative
Stress ensue.
Poor Absorption
of nutrient leads to
multiple deficiencies.
Altered Gut Microbial Ecology
causes an imbalance of microbial powers which:
• Magnifies life stressors
• Amplifies your immune response
• Inhibits corrective homeostatic measures.

10. I Can’t Say It Loudly
Enough:
JUST BECAUSE YOU
HAVE TESTED
NEGATIVE FOR CELIAC
AND WHEAT ALLERGY
IN THE PAST DOES NOT
MEAN YOU DO NOT
HAVE GLUTEN
SENSITIVITY!

11. Which is why, when we
test, we use the gold
standard: Cyrex Array 3 –
Wheat Gluten Autoimmunity
Reactivity Profile.
Routine tests for
“celiac disease” miss
too many case of NCGS.
Cyrex Array 3 – Wheat Gluten Autoimmunity Reactivity Profile is the most
sensitive test available for gluten reactivity. Measuring immune response to an
array of wheat antigens increases the sensitivity and specificity, and will provide
greater confidence in formulation of a diagnosis that allows for better patient
compliance with a gluten-free diet.

12. Available at
Healthremedies.com
Toll Free: (800) 385-7863
Fax: (941) 371-7667
info@healthremedies.com