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Edmonton Obesity Staging
    System (EOSS)
         Arya M Sharma, MD, FRCP(C)
               Professor of Medicine
    Chair in Obesity Research & Management
                University of Alberta
              Edmonton, AB, Canada
                 www.drsharma.ca
www.drsharma.ca
Edmonton Obesity Staging System (EOSS)

                   Stage 2
                   co-morbidity

                    moderate
    Stage 1                                    Stage 3
                    moderate




Stage 0                                             Stage 4
                    Obesity




www.drsharma.ca        Sharma AM & Kushner RF, Int J Obes 2009
Edmonton Obesity Staging System (EOSS)

                            Hypertension

                                 Stage 2

                                 Hypertension

    Stage 1           Pre-                       LVH         Stage 3
                  hypertension                   CHD


Stage 0      Normal                                     Heart    Stage 4
          blood pressure                               Failure




www.drsharma.ca                     Sharma AM & Kushner RF, Int J Obes 2009
Edmonton Obesity Staging System (EOSS)

                           Type 2 Diabetes

                              Stage 2

                                Type 2
                               Diabetes
    Stage 1         IFT/                  Micro-/macro-   Stage 3
                    IGT                     vascular
                                               disease

Stage 0       Normal
           blood glucose                           Blindness   Stage 4
                                                    ESRD




www.drsharma.ca                  Sharma AM & Kushner RF, Int J Obes 2009
www.drsharma.ca
EOSS Predicts Mortality in NHANES III




www.drsharma.ca         Padwal R, Sharma AM et al. CMAJ 2011
EOSS Predicts Mortality at Every Level of BMI
NHANES III




                                           Overweight




www.drsharma.ca           Padwal R, Sharma AM et al. CMAJ 2011
www.drsharma.ca
Association Between EOSS and Mortality Risk in
Aerobics Center Longitudinal Study (n = 29 533)




www.drsharma.ca    Kuk JL, et al. Appl. Physiol. Nutr. Metab. 2011;36: 570
EOSS Distribution Across BMI Categories
NHANES III (1988-1994)

                                                     14%            8%


                                                                         19%


           10%
                   15%
                                                         Class I

                                                      59%
                                        5%
                                 14%

          Overweight                         17%
                                                    23 million
                         28%
                                  Class II
    47%

                                  64%
                                                         5%              EOSS Stage
                                                   14%
                                                              14%
                                                                         0
                                 10 million         Class
                                                                         EOSS Stage
                                                      III
                                                                         1
          50 million                                 67%
                                                                         EOSS Stage
                                                   6 million             2

www.drsharma.ca                Padwal R, Sharma AM et al. CMAJ 2011
EOSS Case 1

          24 year-old physically active female,
                     BMI of 32 Kg/m2
        no demonstrable risk factors, no functional
           limitations, or mental health issues

                  Class I, Stage 0 Obesity

      - Focus on prevention of further weight gain
      - Health benefits of more aggressive obesity
                treatment likely marginal

www.drsharma.ca            Sharma AM & Kushner RF, Int J Obes 2009
EOSS Case 2

                    32 year-old male
                    BMI of 36 Kg/m2
          hypertension, sleep apnea, depression

                  Class 2, Stage 2 Obesity

            - Clear benefits of obesity treatment




www.drsharma.ca             Sharma AM & Kushner RF, Int J Obes 2009
EOSS Case 3

                   63 year-old male
                   BMI of 74 Kg/m2
         disabling osteoarthritis (wheel chair)
   severe hypoventilation, fibromyalgia, generalized
                   anxiety disorder

                  Class 3, Stage 4 Obesity

     - Aggressive obesity treatment unless deemed
                       palliative

www.drsharma.ca             Sharma AM & Kushner RF, Int J Obes 2009
www.drsharma.ca
www.drsharma.ca
www.drsharma.ca
Key Points

• EOSS provides a rational framework for clinical
  prioritization and management
• EOSS stage is a better predictor of obesity risk
  than BMI or waist circumference
• Assessing EOSS stage should be part of the
  clinical assessment of obesity
• Management strategies should be based on
  EOSS stage




www.drsharma.ca
www.DrSharma.ca

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Edmonton obesity staging system

  • 1. Edmonton Obesity Staging System (EOSS) Arya M Sharma, MD, FRCP(C) Professor of Medicine Chair in Obesity Research & Management University of Alberta Edmonton, AB, Canada www.drsharma.ca
  • 3. Edmonton Obesity Staging System (EOSS) Stage 2 co-morbidity moderate Stage 1 Stage 3 moderate Stage 0 Stage 4 Obesity www.drsharma.ca Sharma AM & Kushner RF, Int J Obes 2009
  • 4. Edmonton Obesity Staging System (EOSS) Hypertension Stage 2 Hypertension Stage 1 Pre- LVH Stage 3 hypertension CHD Stage 0 Normal Heart Stage 4 blood pressure Failure www.drsharma.ca Sharma AM & Kushner RF, Int J Obes 2009
  • 5. Edmonton Obesity Staging System (EOSS) Type 2 Diabetes Stage 2 Type 2 Diabetes Stage 1 IFT/ Micro-/macro- Stage 3 IGT vascular disease Stage 0 Normal blood glucose Blindness Stage 4 ESRD www.drsharma.ca Sharma AM & Kushner RF, Int J Obes 2009
  • 7. EOSS Predicts Mortality in NHANES III www.drsharma.ca Padwal R, Sharma AM et al. CMAJ 2011
  • 8. EOSS Predicts Mortality at Every Level of BMI NHANES III Overweight www.drsharma.ca Padwal R, Sharma AM et al. CMAJ 2011
  • 10. Association Between EOSS and Mortality Risk in Aerobics Center Longitudinal Study (n = 29 533) www.drsharma.ca Kuk JL, et al. Appl. Physiol. Nutr. Metab. 2011;36: 570
  • 11. EOSS Distribution Across BMI Categories NHANES III (1988-1994) 14% 8% 19% 10% 15% Class I 59% 5% 14% Overweight 17% 23 million 28% Class II 47% 64% 5% EOSS Stage 14% 14% 0 10 million Class EOSS Stage III 1 50 million 67% EOSS Stage 6 million 2 www.drsharma.ca Padwal R, Sharma AM et al. CMAJ 2011
  • 12. EOSS Case 1 24 year-old physically active female, BMI of 32 Kg/m2 no demonstrable risk factors, no functional limitations, or mental health issues Class I, Stage 0 Obesity - Focus on prevention of further weight gain - Health benefits of more aggressive obesity treatment likely marginal www.drsharma.ca Sharma AM & Kushner RF, Int J Obes 2009
  • 13. EOSS Case 2 32 year-old male BMI of 36 Kg/m2 hypertension, sleep apnea, depression Class 2, Stage 2 Obesity - Clear benefits of obesity treatment www.drsharma.ca Sharma AM & Kushner RF, Int J Obes 2009
  • 14. EOSS Case 3 63 year-old male BMI of 74 Kg/m2 disabling osteoarthritis (wheel chair) severe hypoventilation, fibromyalgia, generalized anxiety disorder Class 3, Stage 4 Obesity - Aggressive obesity treatment unless deemed palliative www.drsharma.ca Sharma AM & Kushner RF, Int J Obes 2009
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  • 19. Key Points • EOSS provides a rational framework for clinical prioritization and management • EOSS stage is a better predictor of obesity risk than BMI or waist circumference • Assessing EOSS stage should be part of the clinical assessment of obesity • Management strategies should be based on EOSS stage www.drsharma.ca