1. Cysts

2. Pathology Lab
Amin Abusallamh

3. goblet
stratified
Cystic cavity
squamous
epithelium
BM
CT
Dentigerous cyst
1. Stratified squamous epithelium with goblet & mucous cells .
2. C.T. conatining numerous fibroblasts & collagen fibers

4. stratified squamous
epithelium
Cystic cavity fill
with keratin
Junction between
epith. And CT is flat
Keratocyst:
- stratified squamous epithelium .
- corregated epithelial lining .
- polarized basal cell with tomb stone pattern .

5. stratified squamous epithelium
tall columnar epithelium B M
CT
keratinized
epithelium
(ghost cell)
Calcifying Epithelial Odontogenic Cyst
- tall columnar epithelium .
- hyperchromatic nucleous away from the basal cells .
- stellate reticulum containig ameloblastic-like cells between the inner
and outer enamel epithelium ,

6. Cyst cavity
stratified squamous
epithelium eosinophilic bodies
Basement membrane C.T containing
lymphocytes +
inflammatory cells
Radicular cyst:
- thick stratified squamous epithelium because of chronic inflammation .
- C.T containing lymphocytes + inflammatory cells .
- characteristis feature is >>> eosinophilic bodies ( rashtom's )

7. Cyst cavity
RBC
giant cells
reactive osteoid tissue
Aneurysmal bone cyst
- pseudocyst .
- neumerous blood sinusoids with RBCs .
- multinucleated giant cells in C.T. stroma .
- reactive osteoid tissue .

8. granulation tissue
mucous secretion
minro salivary glands
Mucocele (Mucous extravasation Phenomenon
- mucous secretion located in the center .
- it has a granulation tissue .
- numerous minro salivary glands .

9. Odontogenic tumors

10. follicle epithelium
C.T
central cells
pripheral columnar Ameloblastoma
Picture 1 : Follicular ameloblastoma . Picture 2 : Plyxiform ameloblastoma .
- epithelial follicles in C.T stroma . - pripheral tall columnar cells ( ameloblast like
cells ) .
- in the follicle : - central cells ( stellate reticulum like cells ) .
* pripheral columnar cells ( ameloblast like cells ) . - C.T. stroma in between .
* central cells ( stellate reticulum like cells ) .

11. Cannulated tubule Tall columnar
Adenomatoid Odontogenic Tumors (AOT)
Basal cell
-sheets of polyhidral odontogenic epithelium .
-- duct like structures lined by one or two layers of columnar cells
( ameloblast like cells ) with band of eosinophilic material in between .

12. cementum or
bone trabeculae
Cementoifying fibroma
-mesenchymal odontogenic tumor ,
-fibrous proliferating delicate C.T. ( fibers + fibroblasts ) scattered with
numerous calcification which either cementum or bone trabeculae .

13. cementume
Fibrous stroma Cementoblastoma
-proliferating cementume-like structures .
--masses of cementum formed by cementoblasts in priphery with
fibroblast in the center .

14. islands of epithelial
columnar cells
C.T
stellate reticulum-
Ameloblastic Fibroma like cells
rosets/islands of epithelial tissue in proliferating neoplastic delicated
fibrous C.T .
- in the priphery : columnar cells ( ameloblast-like cells ) .
- in the center : stellate reticulum-like cells .

15. Bone Diseases

16. Incearse number of oteocyte and osteoblast
woven bone
Osteoid non
mineralization
Osteogenesis Imperfecta (OI)
1. Replacing of bone with irregular ammature woven bone
2. Incearse number of oteocyte and osteoblast
3. Osteoid non mineralization

17. multinucleated
osteoclast
Osteopetrosis
1. dense thick bone trabeculae with numerous inactive
multinucleated osteoclast
2. Decease the bone marrow and its fiber

18. multinucleated giant blood vessels ossteoed tissue)
Cherubism fibrous tissue
1. Replacing of bone by fibrous tissue
2. (Highly fibroblast + blood vessels + collagen fiber + multinucleated giant
cells + ossteoed tissue)

19. Thin slender
irregular bone
trabeculae
fibrous tissue
Fibrous dysplasia of bone (FD
1. Thin slender irregular bone trabeculae in fibrous tissue stroma take
the shape of Chinese letter.
2. Replacing of bone with fibrous tissue.

20. giant cell
connective tissue
BV
hemosiderin
Brown node of hyperparathyroidism
Replacing of bone with highly cellular connective tissue with numerous
multinucleated giant cell + BV + pigment hemosiderin

21. giant cell
reversal line
prominent osteoblast
and osteoclast
Paget’s disease of bone
1. High dense thick irregular bone trabeculae with numerous
multinucleated giant cell + BV + prominent reversal line + prominent
osteoblast and osteoclast
1. The marrow has been replaced by fibrous tissue

22. BV
chronic
inflammatory giant cell
cells
reversal line
empty lacuna of
death osteocyte
Chronic focal sclerosing osteomyelitis
1. thick irregular bone trabeculae with multinucleated giant cell + BV
+ reversal line + empty lacuna of death osteocyte
2. Fibrotic Bone marrow with chronic inflammatory cells