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Russian National Contact Point
           on «Food, Agriculture, Fisheries & Biotechnology»
     (Bio-NCP of Russia on FP6-FP7 Programmes of EC)




  Russian Approach and Experience as
Regards a Successful S&T Cooperation and
           Participation in FP7

                                                 Vladimir ERYOMIN
                                          Scientific Counsellor of Bio-NCP of Russia
                                              Bakh Institute of Biochemistry, RAS

Scientific Workshop: “Identification of concrete
sub-topics of the S&T EU-Ukraine cooperation: medium-
sub-                   EU-                    medium-
term outlook. Role of the Working Groups”
                                  Groups”
Kiev, Ukraine, 23 September 2009
                                                                                       1
OUTLINE of Presentation
  OUTLINE of Presentation
Bio-NCP of Russia
(Creation, objectives & tasks, main activities)

European and Russian Technology
Platforms on FAFB Priorities

EU-Russia Working Group on Agro-Food-
Biotech Priorities

EU-Russia Co-funded in Coordinated
Calls in FP7 Programme EC

                                                  2
Bio-NCP of Russia
          Bio-NCP of Russia
        A.N. BAKH
         A.N. BAKH
        INSTITUTE OF
         INSTITUTE OF
        BIOCHEMISTRY
         BIOCHEMISTRY
        RAS (INBI)
         RAS (INBI)


Bio-NCP of Russia (formerly - Food-NCP in FP6) was
established by the Ministry of Science and
Education of the RF on the basis of A.N. Bakh
Institute of Biochemistry of Russian Academy of
Sciences in May 2003
The main objective of Bio-NCP of Russia is
promotion of Russian science integration into the
European Research Area («ERA») by participation in
FP6-FP7 Programmes of EC
                                                 3
Bio-NCP of Russia
            Bio-NCP of Russia
Our activity is directed to:
  Increasing of Russian participation in EC FP7 Programme
  on FAFB priorities
  Consulting & training, information assurance and
  dissemination, accompanying projects, etc.
  Increasing capacity building for Russian R&TD community
  Consulting and direct contacts with Russian governing bodies
  (Government agencies, Ministry of Education &Science of the
  RF, stakeholders, multipliers, administration of scientific
  Centres and Institutes, SME representatives, etc.) (EU-Russia
  Working Group – Russian Policymakers and representatives
  of EC Directorate)
  Structuring of R&TD community in the Russian Federation
  Monitoring and coordination of participation activity in FP7 on
  FABF Priorities
                                                               4
Bio-NCP of Russia
                             Bio-NCP of Russia
                       Main Tasks and Activities
                       Main Tasks and Activities
Mapping                        Dissemination             All-round help to
Research activities            FPs rules, materials      EU-Russia Working Group
                               and activities and
                                                         on Agro-Food-Biotech
Revealing                      liaison building
Centres of excellence
                                                         priorities
(Laboratories, Institutes,     Training & Consulting     Communication
etc.) , Major R&TD             Researchers and            with EC Directorate
infrastructure in Russia       Multipliers               and European TP
                               Facilitation of
                               international contacts,   Coordination of R&TD
                               communications and        cooperation
Matching                                                 Ministry of Education and
                               cooperation with other
EU and Russia R&TD                                       Science RF
                               countries in FPs and
Priorities                                               Federal Agency for
                               bilateral collaboration
                                                         Science and Innovation
Structuring
R&TD Community                 Enhancing                 Participation and holding
                               Capacity building of      EU-Russia International
                               NCPs, and acting and      Symposiums, Forums, S&T Events
                               potential Russian
                               participants of FPs       Co-funded and Coordinated Calls

  Involvement and encouragement of acting and potential
  Russian participants into FP7 European R&TD Network
                                                                                          5
Bio-NCP of Russia
              Bio-NCP of Russia
Our activity is directed to:
  Studying of European Conception of Technology
  Platforms and relevant activity in FAFB Sector of FP7
  Revealing of Russian National Priorities in FAFB Sector
  of FP7
  Formation of Russian Technology Platforms in FAFB
  Sector of FP7
  Coupling of European Conception of Technology
  Platforms to development of Technology Platforms in
  Russia
  Coordination of efforts and activity for Russian participation
  in FP7 on FAFB Priorities (EU-Russia Working Groups)
  Development of joined mechanisms and new ways for R&TD
  collaboration between EU and Russia (e.g. Co-funded &
  coordinated Calls, EU-Russia Working Groups)
                                                             6
European Technology Platforms (TPs)

Technology Platforms (TPs) are the instruments for formation of
      priorities for International R&TD co-operation in countries of
      the European Union (MS and AC) and other 3-d INCO-
      countries co-operating with the EU.




Technology Platforms (TPs) are the practical tools for realization of
                     FP7 Programme of EC

                                                                        7
Conception of Technology Platforms
Selection of the most strategically important
applied scientific challenges for social and economical
development of EU-countries
Analysis of Market needs and available technology
transfers potential for production of consumer’s goods
and service enhancing
Active involvement of all EU-countries and INCO-
countries
Mobilization of public and private financial
resources for FP7 Programme realisation
Mobilization of human resources for implementation
of Projects
                                                          8
Conception of Technology Platforms
Taking into account all points of view:
(for all interested-in Sides)
Government Bodies
Regulatory Bodies
Representatives of Industry

Scientific Communities
SMEs
Multipliers
Consumers and Users

    The European Conception of
«KNOWLEDGE-BASED BIO-ECONOMY»
                                          9
The European Conception of
                                        The European Conception of
                                    «KNOWLEDGE-BASED BIO-ECONOMY»
                                    «KNOWLEDGE-BASED BIO-ECONOMY»
   QUALITY ASSURANCE
    QUALITY ASSURANCE                                                 STABILITY --
                                                                      STABILITY
 STRATEGIES TRACEABILITY,
 STRATEGIES TRACEABILITY,           SOCIETAL NEEDS
                                    SOCIETAL NEEDS                BIODEGRADABILITY
                                                                  BIODEGRADABILITY
    CONSUMER SCIENCE
    CONSUMER SCIENCE                                                FUNCTIONALITY
                                                                    FUNCTIONALITY


                                                                    Life Sciences &
  “Fork to Farm”                                                  Biotechnology for
   Food, health                                                      Sustainable
  and well-being                                                  non-food products
                                                                     + processes

                                                                  WHITE BIOTECH
      ADVANCED FOOD
TECHNOLOGIES, FOOD QUALITY             PROCESSING              CLEAN BIOPROCESSES
  DETERMINANTS, NUTRITION                                      RAW MATERIALS/WASTE


LOW INPUT FARMING -- BIODIVERSITY
LOW INPUT FARMING BIODIVERSITY                                 GREEN/BLUE BIOTECH
                                                                GREEN/BLUE BIOTECH
ANIMAL HEALTH -- RURAL DEVT.
ANIMAL HEALTH RURAL DEVT.              PRODUCTION            OPTIMISED RAW MATERIALS
                                                             OPTIMISED RAW MATERIALS


  Sustainable production and management of biological resources
             from land, forest, and aquatic environments
                                                                                            10
                                                 Compiled from Dr. Ch. Patermann presentation
European Technology Platforms (TPs)
From: http://cordis.europa.eu/technology-platforms/individual_en.html




                                                                        11
European Technology Platforms (TPs)

 TPs of EC are formed on the basis of European
Conception of «Knowledge-Based Bio-Economy»


                                    Food
                                   for Life

              Global Animal                          Bio-Fuels
                 Health

                             Knowledge-
                                Based
                             Bio-Economy
             Forestry                                      Farm Animal
                                                             Breeding




                           Industrial         Plants for
                        Bio-Technology        the Future

                                                                         12
Russian National Priorities
Russian National Priorities in Science, Technology and
Technique Areas:
  Biotechnology for life (Industrial Biotechnology for agriculture,
  food, forestry, fishery, bio-fuel, etc.)
  System Biology (all with –”omics” – genomics, proteomics,
  metabolomics, transcritomics, fluxomics, etc.)
  Bioengineering technologies
  Bio-informatics technologies
  Cell technologies including stem cells
  Bio-sensing technologies
  Biocatalysts and biosynthetic technologies, etc.
  Biotechnology for medicine (pharmaceutical, organ therapy, etc.)
  Health & Life Sciences (Critical Technologies of the live systems
  and in Life Science)
  Biomedical technologies for life support and human protection
  Genomic and post genomic technologies for drug development
  Nanotechnologies and materials
  Information- and telecommunication technologies and electronics
  Energy and energy-saving
  Advanced and special machinery and equipment
  Environment protection and rational nature management
  Security and anti-terrorism activities, etc., etc.                13
Main Activity of Bio-NCP of Russia
             in Formation of Russian TPs
Selection of National Thematic Priorities for
Formation of Russian TPs for Participation in FP7
Programme of EC
  Food Biotechnology
     MSU of Applied Biotechnology,
     Institute of Nutrition RAMS, etc.
  Industrial Biotechnology
     Institute Biochemistry RAS, MSU,
     Institute of Genetics, etc.
  Biotechnology of Plants
     Centre of Bio-engineering RAS, etc.
  Forestry
     MSU of Forest, Centre of Forest
     Ecology and Production RAS, etc.
  Animal Health
     State Institute of Animal Feed, etc.
                                                    14
Principles of Russian Technology
                   Platform Formation

                                                                 European
                                                                 European
                                    Coordinator
                                                                Biofuels TP
                                                                Biofuels TP
     Bio-NCP                          Centre
     of Russia


                    Management
                       Body




Scientific Centre
Scientific Centre     Scientific Centre
                      Scientific Centre     Scientific Centre
                                            Scientific Centre   Scientific Centre
                                                                Scientific Centre
    Experts
    Experts               Experts
                          Experts               Experts
                                                Experts             Experts
                                                                    Experts
                    Plants for the Future

                                                                             15
Russian Technology Platform
          “Food for Life”- STRUCTURE:

       Russian                                    Contacts with
     National FAFB                               governmental &
     Contact Point         Secretariat              legislative
         FP6/7           of the Platform              bodies
            20 members

   Research                           Unions of
                 Leading food      manufacturers      Associations
 institutions     enterprises     in different food   of consumers
& Universities                    industry sectors


                     Lines of activities:

Food industry        Food quality control        Healthy nutrition

                                                                     16
Russian Technology Platform
                           Russian Technology Platform
                       “Food for Life”- MAIN PARTICIPANTS:
                       “Food for Life”- MAIN PARTICIPANTS:
                                            MOSCOW STATE
                                             MOSCOW STATE
                 MOSCOW STATE UNIVERSITY
                  MOSCOW STATE UNIVERSITY     UNIVERSITY
                                               UNIVERSITY
                 OF APPLIED BIOTECHNOLOGY
                 OF APPLIED BIOTECHNOLOGY OF FOOD PRODUCTION
                                          OF FOOD PRODUCTION




Institute of                                                            MSUFP
Biological Industry


Institute of Fishery                                                Institute of
and Oceanography          INSTITUTE OF
                          INSTITUTE OF   A.N. BAKH INSTITUTE OF
                                         A.N. BAKH INSTITUTE OF     Childish Food
                            NUTRITION
                            NUTRITION      BIOCHEMISTRY RAS
                                           BIOCHEMISTRY RAS
Institute of                                                      Institute of Poultry
                                                                  Processing Industry
Dairy Industry
                                                                  Institute of Control,
Institute of                                                      Standardization, Certifica-
                                                                                    Certifica-
Meat Industry                                                     tion of Veterinary
                                                                  Preparations



                                                                                         17
Examples of Russian Consortia
          in Technology Platforms

 A.N. Bakh Institute     Moscow State
                                               GosGNIIgenetika
of Biochemistry, RAS      University
                                                   Institute
 Puschino Research
                        SME «VOSTOK»            of Microbiology
   Centre of RAS
                                                    of RAS

  SME «Rosalko»        Institute of Plastics        6 SMEs

     Institute of
                                               Centre of Cardiac
    Engineering          Textile Institute
                                                Surgery RAMS
      Ecology




                                                                   18
Structuring of Russian
 Biotech Community




                         19
Russian TPs on FAFB in FP7
   Russian TPs on FAFB in FP7
   Russian TPs on FAFB in FP7
Food Quality & Safety
Food Quality & Safety
Industrial Biotechnology
Industrial Biotechnology
Forestry
Forestry
Plants for the Future
Plants for the Future
Animal Health
Animal Health
Fisheries
Fisheries
Bio-fuel
Bio-fuel


                                20
EU-Russia Working Group on
     Agro-Food-Biotech Priorities
                    (Proposed Structure)
    From Russia                            From EU
Representatives of Ministry
                                  Representatives of EC
of Education and Science of
                                  Directorate on FAFB priorities
the RF
Representatives of Russian        Representatives of EU
Federal Agency for Science        Technology Platforms
and Innovation
                                  Heads of EU FP6-FP7
Representatives of Bio-NCP
                                  Megaprojects
of Russia
Representatives of Russian        Representatives of European
Technology Platforms              Bio-NCPs
Russian R&TD Experts
                                  European R&TD Experts
(Usually Directors of RTD
Centres)
                        Secretariat                             21
Prospects for Future EU-Russia Cooperation




    Inna Bilenkina,                                               Christian Patermann,
    Deputy Head of Russia's Federal Agency for                    Director of EC Directorate for
    Science and Innovation,                                       «Biotechnologies, Agriculture, Fisheries &
    CORDIS News interview – «EU and Russia Strengthen             Food»
    Research Ties»                                                CORDIS Video interview - «Talking about
    (http://cordis.europa.eu/fetch?CALLER=KBBENEWS&)              FP7» Prospects for Future EU-Russia
                                                                  Cooperation Initiatives
From 2008, scientific research in Russia will be
                                                                  Mr. Patermann met his Russian colleagues of
supported from Government by two large scale                      the EC-Russia Working Group on Agro-Bio-
programmes:                                                       Food in Suzdal, Russia and talks about new
First programme is dedicated to the                               ways in EU-Russia cooperation.
New Materials and Nanotechnologies (~ 40% of the Russian funds)   (http://cordis.europa.eu/fp7/kbbe/interview_en.
Life Sciences and Biotechnology – (~25%)                          html)
Energy and Energy Efficiency
Rational Nature Use
Information and Communication Technologies (ICTs).

The second programme is dedicated to the
Industrial Development of Nanotechnologies and New
Materials.                                                                                                          22
EU-Russia Working Group on
«Health and Life Sciences» Priorities
Co-funded and Coordinated Calls on «Health»




 Working Group Meeting on «Heath and Life Sciences» at the
 Federal Agency for Science and Innovation, Moscow, 12-th
 of March 2009,
                        For more details see, http://www.fasi.gov.ru/news/press-c/1636/
                                              http://www.fasi.gov.ru/news/press-
                                                                                          23
EU-Russia Working Group on
       Agro-Food-Biotech Priorities
       (Scheme of decision making and basic documents)

       EU-RF Declaration of Collaboration

RF Topics of Interest             EU Topics of Interest


           Mutual Topics of Interest

          Minutes of WG Meetings

      Co-funded and Coordinated Calls
                                                         24
EC-Russia Coordinated Calls in FP7-TP-FABF
•   Date of publication: 30 November 2007                          FP7 Call KBBE-2008-2B
•   Deadline: 26 February 2008                                    In Coordination with Russia
•   Total budget of call FP7-KBBE-2008-2B: 96.85M€
•   Indicative budget dedicated to the coordination activity with Russia: 2+2 M€ (EC+Russia
    contribution)
         Topic KBBE-2008-3-1-04: Plant-produced vaccines
        Topic KBBE-2008-3-2-01: Molecular modelling for rational design of
        industrial enzymes
                                                                                   KBBE- Activity 2.3
                                                                                   KBBE-
                                KBBE- Activity 2.2
                                KBBE-                                          Biotechnologies 17,56 M €
                                 Food 25,58 M €



              KBBE- Activity 2.1
              KBBE-                                                              KBBE- Activity 2.3
          Sustainable Production and                                             Biotechnologies 4 M €
           Management of Biological                                              Coordinated & co-funded
           Resources      48,21 M €
                                                                                 SCP with Russian
                                                                                 participants
                                                                                Activity 2.4 - Network of Third
                                                                                     Countries National Information
                                           www.cordis.europa.eu/fp7/kbbe/home_en.htm Points

                                                                                                                    25
                                                                            Compiled from Dr. Elisabetta BALZI presentation
FABF-TP EC-Russia Coordinated Calls

Date of publication: 30 November 2007
Deadline: 26 February 2008
Indicative budget: 4 M€ (contribution: 2 M€ Russia                 +2 M€ EC)
Funding Scheme: Small Collaborative Project (SCP)

    Topic KBBE-2008-3-1-04:
    Plant-Produced Vaccines
    (Продуцируемые растениями вакцины)
    Topic KBBE-2008-3-2-01:
    Molecular Modelling for Rational Design of Industrial
    Enzymes (Молекулярное моделирование для рационального дизайна
    промышленных ферментов)

All specific arrangements for this particular Call is set out in the relevant Guide
for Applicants
                                                                                      26
FABF-TP EC Russia Coordinated Calls
           KBBE-2008-3-1-04 : Plant        - produced Vaccines
This project will focus on the development of innovative vaccines using plants as
production systems.
Plants offer many advantages over current production platforms by combining the benefits of
traditional fermentor systems (containment, precise growth conditions) with those of plants
(economy, safety, scalability). Specific technologies have been developed recently for the
production of high-value recombinant proteins in plants. Remaining bottlenecks for these
technologies include low yield of recombinant proteins, high production costs and lengthy
development and testing of the plants.
The overall aim of the project will be to identify and establish higher antigen yields
production systems, which are highly controllable and reproducible. This includes the
selection of the most suitable plant species and culture conditions, improved understanding
of antigen presentation and immunity, rapid screening and up-scaling, rapid development of
vaccine variants and novel technologies for improved vaccine production.

Expected impact: High efficiency and low cost production of vaccines. The project is
expected to contribute to the "EU-Russia Common Space for Education and Research" and
to the S&T bilateral agreement between the European Community and the Russian
Federation and to the EU-South Africa dialogue on KBBE on the basis of mutual interest and
shared benefits.
Scientific Officer: Tomasz Calikowski, email: Tomasz.Calikowski@ec.europa.eu           27
FABF-TP EC Russia Coordinated Calls
                                    KBBE-2008-3-2-01:
     Molecular Modelling for Rational Design of Industrial
                          Enzymes
Enzymes are increasingly used in the chemical industry. Computational chemistry,
bioinformatics, enzyme structure modelling, molecular docking and dynamics, quantum
chemistry and corresponding hybrid methods have been developed to describe the intimate
details of the bio-catalytic mechanisms.
The objective of the topic is to develop rational enzyme design methods based on molecular
(in-silico) modelling in order to produce a next generation of highly efficient biocatalysts
with an expanded range of substrates, improved enantio-selectivity and enhanced catalytic
activity for industrially important conversions. Optimization of multi-enzyme complexes
should also be considered. Research should address the development of quantitative
parameters which adequately describe the efficiency of the biocatalysts under development.
Improved enzymes are particularly required in certain technological areas, such as fine
organic synthesis, bio-transformations, biomass conversion and the food industry.

Expected impact: Enhance industry's capabilities for rational design of biocatalysts and
their fast quantitative evaluation. The project is expected to contribute to the "EU-Russia
Common Space for Education and Research" and to the bilateral S&T agreement between
the European Community and the Russian Federation, on the basis of mutual interest and     28
shared benefits
TP-ENERGY EC-Russia Coordinated Calls

Date of publication: 30 November 2007
Deadline: 26 February 2008
Indicative budget: 4 M€ (contribution: 2 M€ Russia +2 M€ EC)

    Topic ENERGY.2008.2.2.1:
    Enhancing strategic international cooperation
    with Russia in the field of power generation from
    biomass (Производство электроэнергии из биомассы)
    Topic ENERGY.2008.7.2.3:
    Innovative operational and monitoring tools for
    large power systems (Системы управления и оборудование
    для крупных энергетических сетей)

All specific arrangements for this particular Call is set out in the relevant
Guide for Applicants
                                                                                29
ENERGY: EC-Russia Coordinated Calls
Enhancing strategic international cooperation with
Russia in the field of power generation from biomass

Content/scope: Research and technology development in the
field of power generation from biomass. The co-operation activity
should be based on an assessment of ongoing research, the
identification of best practices, gaps in knowledge and barriers to
implementation in both, the EU and Russia, and propose
direction for a collaborative research project in the area.
Funding scheme: Collaborative Project (the project duration is
normally 3 years)
Expected impact: Effective cooperation between key
researchers and industries in the field of power generation from
biomass should foster the development and uptake of innovative
methods and technologies to expand the use of biomass in
power generation.
                                                                  30
Indicative Time Table
                     for EC-Russia Coordinated Calls

                                       EU                     Russia
Launch of the EC Call           30 November 2007

Launch of the RU Call                                   End of January 2008

Submission deadline EU Call     26 February 2008

Submission Deadline RU Call                              End of April 2008

Completion of EU evaluation   Beginning of April 2008

Completion of RU evaluation                               Mid of May 2008

End of EU negotiations          Mid of July 2008

Signature of EC GA             By September 2008

Signature of RU contracts                               By end of June 2008

Start of projects                  Starting around the end of 2008

                                                                              31
Call principles
                           for EC-Russia Coordinated Calls
                           SMALL COLLABORATIVE PROJECT
 Corresponding                                                                            Joint technical
Russian part in                                                                               Annex
                                       Integrated
the joint project
                           Min. 2 RU activities Min. 2-3 MS
                          participants               or AS
                                                  participants
  Submission
                                                                                            Submission of
  of tender to
                                                                                                a Joint
  the Russian
                                                        < 5%              All                proposals to
      Call               RU                            of TEC        participants           FP7 EU-Russia
  according to      participants                                     sign the EU            Call according
   FASI rules          sign a                                          FP7 GA
                     contract                                                                to FP7 rules
                     with FASI

                             FASI                           EC
                            Budget:                       Budget:
   Evaluation                                                                            EC
                            Max. 2M€                      Max. 2M€
  according RU                                                                        Evaluation
      rules                                EU-RU                                      according
                                         concerted
                                          dialogue
                                                                                      FP7 rules

                              Compiled from presentation of Gilles Lequeux, European Commission, DG Research
                                                                                                               32
Overview of the Evaluation Process
                           EU-RUSSIA Co-ordinated and Co-funded Projects
                    be ”
                ay ote
               M m
                “re

                       Individual
Submission                                 Consensus      Panel          Finalisation
                         reading


                                                                           Final
                           Evaluators      Evaluators   Evaluators         ranking
 Full Proposal                                                             list

 Proposal                                                                 Rejection list
                           Criteria        Criteria     Criteria
 forms
                                                        Proposals in
 Eligibility                                            suggested
                                                        priority order
COMMISSION                                                               COMMISSION


                                      Role of experts                                33
FABF-TP EC Russia Coordinated Calls

Minimum Number of Participants:

2 from different EU Member States or FP-Associated
   Countries* and
 2 from different Federal units (provinces, oblasts,
republics,
   territories, districts, Federal cities) from Russia.
* FP-Associated Countries: Croatia, Turkey, Serbia, FYROM, Iceland, Israel, Liechtenstein, Norway,
Switzerland, and as from 01/01/08 Montenegro and Albania


In addition, this research area is particularly well suited for cooperation with other ICPC
countries with bilateral S&T agreements with the European Community** such as South
Africa, and this will be reflected in the evaluation

** ICPC countries with bilateral S&T agreements with the European Community:
Argentina, Brazil, Chile, China, Egypt, India, Mexico, Morocco, Russia, South Africa, Tunisia and Ukraine
                                                                                                      34
FP7 Funding rules for Collaborative Projects

R&D Activities:
- EU grant up to 50% of the total eligible cost.
- Certain legal entities can receive up to 75% (non-profit
public bodies, Small and Medium Size Enterprises / SMEs,
higher education establishments).
Demonstration Activities:
 - the reimbursement rate may reach 50% of the total eligible cost.
Other activities (consortium management, networking, training,
coordination, dissemination etc. )
- the reimbursement can be up to 100% of the
eligible cost.


                                                                      35
EU‐RUSSIA Symposia
                                  on FP6/7 BIO Priorities
   Important instruments to strengthen EU‐
    Russian сo‐operation in BIO‐TPs of FP7
‐ I Moscow                                                  2004
‐ II Moscow                                                 2005
‐ III St. Petersburg                                        2006
‐ IV Suzdal                                                 2007
‐ V Pushchino                                               2008
‐ German‐Russian Forum in Moscow     2009




                                                                   36
OUTCOMES of EU-RUSSIA Symposium
        “Prospects for R&TD Co-operation in
        Biotechnology in FP7”
        5-8 June 2006 St. Petersburg

Objectives:
 Public establishing EU-Russia Working
Group on Agro-Food-Biotech priorities
 Discussion of key issues and prospective of
R&TD cooperation between Russia and EU in
Biotechnology in FP7
 Discussion of Russian participation in FP7
European Technology Platforms
 Presentation of Russian Technology
Platforms                                      37
OUTCOMES of EU-RUSSIA Symposium
          “Prospects for R&TD Co-operation in
          Biotechnology in FP7”
          5-8 June 2006 St. Petersburg

Main results:
Adopting Joint Declaration of the EU-Russia Working
Group on «Agro-Bio-Food»

  More than 200 scientists, SME representatives and multipliers from
Russia and NIS countries
  About 50 experts from EU
  International School of Young Scientists «Biotechnology for the
Future»
  More than 60 young scientists from EU and NIS
  Brokerage Events and Poster Sections
  «InJoy&Train» Meeting
  Posted Catalogue of Profile Forms (119 proposals) for participation
in EC FP7 FAFB priorities
  Russian-German Satellite Symposium on Bioinformatics Network
                                                                   38
Results of 3 First Calls in FP7 EC
        Funded Projects on FAFB Priorities
          for 3‐d Countries Participation
11 Projects with Russian Participation
23 Entities from Russia
among them:
2 SICA Calls for Russian Participation
2 EU‐Russia Coordinated Projects




                                         2007‐2008
                                                     39
Russian National Contact Point
             on «Food, Agriculture, Fisheries & Biotechnology»
        (Bio-NCP of Russia on FP6-FP7 Programmes of EC)
                                                         Institute of
                                                         Biochemistry




                   Thank you for your attention
                         Good Luck in FP7!
Vladimir ERYOMIN
Scientific Counsellor
(Bio-NCP of Russia)
Institute of Biochemistry, RAS
Leninsky Prospect, 33, 119071 Moscow, RUSSIA
Tel.: +7 (495) 954 44 74
eryomin@inbi.ras.ru
http://www.fp7-bio.ru
                                                                        40

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Vladimir Eryomin, Russ S&T-Cooperation-in-FP7, Kiev-Ukraine, 23-September-2009

  • 1. Russian National Contact Point on «Food, Agriculture, Fisheries & Biotechnology» (Bio-NCP of Russia on FP6-FP7 Programmes of EC) Russian Approach and Experience as Regards a Successful S&T Cooperation and Participation in FP7 Vladimir ERYOMIN Scientific Counsellor of Bio-NCP of Russia Bakh Institute of Biochemistry, RAS Scientific Workshop: “Identification of concrete sub-topics of the S&T EU-Ukraine cooperation: medium- sub- EU- medium- term outlook. Role of the Working Groups” Groups” Kiev, Ukraine, 23 September 2009 1
  • 2. OUTLINE of Presentation OUTLINE of Presentation Bio-NCP of Russia (Creation, objectives & tasks, main activities) European and Russian Technology Platforms on FAFB Priorities EU-Russia Working Group on Agro-Food- Biotech Priorities EU-Russia Co-funded in Coordinated Calls in FP7 Programme EC 2
  • 3. Bio-NCP of Russia Bio-NCP of Russia A.N. BAKH A.N. BAKH INSTITUTE OF INSTITUTE OF BIOCHEMISTRY BIOCHEMISTRY RAS (INBI) RAS (INBI) Bio-NCP of Russia (formerly - Food-NCP in FP6) was established by the Ministry of Science and Education of the RF on the basis of A.N. Bakh Institute of Biochemistry of Russian Academy of Sciences in May 2003 The main objective of Bio-NCP of Russia is promotion of Russian science integration into the European Research Area («ERA») by participation in FP6-FP7 Programmes of EC 3
  • 4. Bio-NCP of Russia Bio-NCP of Russia Our activity is directed to: Increasing of Russian participation in EC FP7 Programme on FAFB priorities Consulting & training, information assurance and dissemination, accompanying projects, etc. Increasing capacity building for Russian R&TD community Consulting and direct contacts with Russian governing bodies (Government agencies, Ministry of Education &Science of the RF, stakeholders, multipliers, administration of scientific Centres and Institutes, SME representatives, etc.) (EU-Russia Working Group – Russian Policymakers and representatives of EC Directorate) Structuring of R&TD community in the Russian Federation Monitoring and coordination of participation activity in FP7 on FABF Priorities 4
  • 5. Bio-NCP of Russia Bio-NCP of Russia Main Tasks and Activities Main Tasks and Activities Mapping Dissemination All-round help to Research activities FPs rules, materials EU-Russia Working Group and activities and on Agro-Food-Biotech Revealing liaison building Centres of excellence priorities (Laboratories, Institutes, Training & Consulting Communication etc.) , Major R&TD Researchers and with EC Directorate infrastructure in Russia Multipliers and European TP Facilitation of international contacts, Coordination of R&TD communications and cooperation Matching Ministry of Education and cooperation with other EU and Russia R&TD Science RF countries in FPs and Priorities Federal Agency for bilateral collaboration Science and Innovation Structuring R&TD Community Enhancing Participation and holding Capacity building of EU-Russia International NCPs, and acting and Symposiums, Forums, S&T Events potential Russian participants of FPs Co-funded and Coordinated Calls Involvement and encouragement of acting and potential Russian participants into FP7 European R&TD Network 5
  • 6. Bio-NCP of Russia Bio-NCP of Russia Our activity is directed to: Studying of European Conception of Technology Platforms and relevant activity in FAFB Sector of FP7 Revealing of Russian National Priorities in FAFB Sector of FP7 Formation of Russian Technology Platforms in FAFB Sector of FP7 Coupling of European Conception of Technology Platforms to development of Technology Platforms in Russia Coordination of efforts and activity for Russian participation in FP7 on FAFB Priorities (EU-Russia Working Groups) Development of joined mechanisms and new ways for R&TD collaboration between EU and Russia (e.g. Co-funded & coordinated Calls, EU-Russia Working Groups) 6
  • 7. European Technology Platforms (TPs) Technology Platforms (TPs) are the instruments for formation of priorities for International R&TD co-operation in countries of the European Union (MS and AC) and other 3-d INCO- countries co-operating with the EU. Technology Platforms (TPs) are the practical tools for realization of FP7 Programme of EC 7
  • 8. Conception of Technology Platforms Selection of the most strategically important applied scientific challenges for social and economical development of EU-countries Analysis of Market needs and available technology transfers potential for production of consumer’s goods and service enhancing Active involvement of all EU-countries and INCO- countries Mobilization of public and private financial resources for FP7 Programme realisation Mobilization of human resources for implementation of Projects 8
  • 9. Conception of Technology Platforms Taking into account all points of view: (for all interested-in Sides) Government Bodies Regulatory Bodies Representatives of Industry Scientific Communities SMEs Multipliers Consumers and Users The European Conception of «KNOWLEDGE-BASED BIO-ECONOMY» 9
  • 10. The European Conception of The European Conception of «KNOWLEDGE-BASED BIO-ECONOMY» «KNOWLEDGE-BASED BIO-ECONOMY» QUALITY ASSURANCE QUALITY ASSURANCE STABILITY -- STABILITY STRATEGIES TRACEABILITY, STRATEGIES TRACEABILITY, SOCIETAL NEEDS SOCIETAL NEEDS BIODEGRADABILITY BIODEGRADABILITY CONSUMER SCIENCE CONSUMER SCIENCE FUNCTIONALITY FUNCTIONALITY Life Sciences & “Fork to Farm” Biotechnology for Food, health Sustainable and well-being non-food products + processes WHITE BIOTECH ADVANCED FOOD TECHNOLOGIES, FOOD QUALITY PROCESSING CLEAN BIOPROCESSES DETERMINANTS, NUTRITION RAW MATERIALS/WASTE LOW INPUT FARMING -- BIODIVERSITY LOW INPUT FARMING BIODIVERSITY GREEN/BLUE BIOTECH GREEN/BLUE BIOTECH ANIMAL HEALTH -- RURAL DEVT. ANIMAL HEALTH RURAL DEVT. PRODUCTION OPTIMISED RAW MATERIALS OPTIMISED RAW MATERIALS Sustainable production and management of biological resources from land, forest, and aquatic environments 10 Compiled from Dr. Ch. Patermann presentation
  • 11. European Technology Platforms (TPs) From: http://cordis.europa.eu/technology-platforms/individual_en.html 11
  • 12. European Technology Platforms (TPs) TPs of EC are formed on the basis of European Conception of «Knowledge-Based Bio-Economy» Food for Life Global Animal Bio-Fuels Health Knowledge- Based Bio-Economy Forestry Farm Animal Breeding Industrial Plants for Bio-Technology the Future 12
  • 13. Russian National Priorities Russian National Priorities in Science, Technology and Technique Areas: Biotechnology for life (Industrial Biotechnology for agriculture, food, forestry, fishery, bio-fuel, etc.) System Biology (all with –”omics” – genomics, proteomics, metabolomics, transcritomics, fluxomics, etc.) Bioengineering technologies Bio-informatics technologies Cell technologies including stem cells Bio-sensing technologies Biocatalysts and biosynthetic technologies, etc. Biotechnology for medicine (pharmaceutical, organ therapy, etc.) Health & Life Sciences (Critical Technologies of the live systems and in Life Science) Biomedical technologies for life support and human protection Genomic and post genomic technologies for drug development Nanotechnologies and materials Information- and telecommunication technologies and electronics Energy and energy-saving Advanced and special machinery and equipment Environment protection and rational nature management Security and anti-terrorism activities, etc., etc. 13
  • 14. Main Activity of Bio-NCP of Russia in Formation of Russian TPs Selection of National Thematic Priorities for Formation of Russian TPs for Participation in FP7 Programme of EC Food Biotechnology MSU of Applied Biotechnology, Institute of Nutrition RAMS, etc. Industrial Biotechnology Institute Biochemistry RAS, MSU, Institute of Genetics, etc. Biotechnology of Plants Centre of Bio-engineering RAS, etc. Forestry MSU of Forest, Centre of Forest Ecology and Production RAS, etc. Animal Health State Institute of Animal Feed, etc. 14
  • 15. Principles of Russian Technology Platform Formation European European Coordinator Biofuels TP Biofuels TP Bio-NCP Centre of Russia Management Body Scientific Centre Scientific Centre Scientific Centre Scientific Centre Scientific Centre Scientific Centre Scientific Centre Scientific Centre Experts Experts Experts Experts Experts Experts Experts Experts Plants for the Future 15
  • 16. Russian Technology Platform “Food for Life”- STRUCTURE: Russian Contacts with National FAFB governmental & Contact Point Secretariat legislative FP6/7 of the Platform bodies 20 members Research Unions of Leading food manufacturers Associations institutions enterprises in different food of consumers & Universities industry sectors Lines of activities: Food industry Food quality control Healthy nutrition 16
  • 17. Russian Technology Platform Russian Technology Platform “Food for Life”- MAIN PARTICIPANTS: “Food for Life”- MAIN PARTICIPANTS: MOSCOW STATE MOSCOW STATE MOSCOW STATE UNIVERSITY MOSCOW STATE UNIVERSITY UNIVERSITY UNIVERSITY OF APPLIED BIOTECHNOLOGY OF APPLIED BIOTECHNOLOGY OF FOOD PRODUCTION OF FOOD PRODUCTION Institute of MSUFP Biological Industry Institute of Fishery Institute of and Oceanography INSTITUTE OF INSTITUTE OF A.N. BAKH INSTITUTE OF A.N. BAKH INSTITUTE OF Childish Food NUTRITION NUTRITION BIOCHEMISTRY RAS BIOCHEMISTRY RAS Institute of Institute of Poultry Processing Industry Dairy Industry Institute of Control, Institute of Standardization, Certifica- Certifica- Meat Industry tion of Veterinary Preparations 17
  • 18. Examples of Russian Consortia in Technology Platforms A.N. Bakh Institute Moscow State GosGNIIgenetika of Biochemistry, RAS University Institute Puschino Research SME «VOSTOK» of Microbiology Centre of RAS of RAS SME «Rosalko» Institute of Plastics 6 SMEs Institute of Centre of Cardiac Engineering Textile Institute Surgery RAMS Ecology 18
  • 19. Structuring of Russian Biotech Community 19
  • 20. Russian TPs on FAFB in FP7 Russian TPs on FAFB in FP7 Russian TPs on FAFB in FP7 Food Quality & Safety Food Quality & Safety Industrial Biotechnology Industrial Biotechnology Forestry Forestry Plants for the Future Plants for the Future Animal Health Animal Health Fisheries Fisheries Bio-fuel Bio-fuel 20
  • 21. EU-Russia Working Group on Agro-Food-Biotech Priorities (Proposed Structure) From Russia From EU Representatives of Ministry Representatives of EC of Education and Science of Directorate on FAFB priorities the RF Representatives of Russian Representatives of EU Federal Agency for Science Technology Platforms and Innovation Heads of EU FP6-FP7 Representatives of Bio-NCP Megaprojects of Russia Representatives of Russian Representatives of European Technology Platforms Bio-NCPs Russian R&TD Experts European R&TD Experts (Usually Directors of RTD Centres) Secretariat 21
  • 22. Prospects for Future EU-Russia Cooperation Inna Bilenkina, Christian Patermann, Deputy Head of Russia's Federal Agency for Director of EC Directorate for Science and Innovation, «Biotechnologies, Agriculture, Fisheries & CORDIS News interview – «EU and Russia Strengthen Food» Research Ties» CORDIS Video interview - «Talking about (http://cordis.europa.eu/fetch?CALLER=KBBENEWS&) FP7» Prospects for Future EU-Russia Cooperation Initiatives From 2008, scientific research in Russia will be Mr. Patermann met his Russian colleagues of supported from Government by two large scale the EC-Russia Working Group on Agro-Bio- programmes: Food in Suzdal, Russia and talks about new First programme is dedicated to the ways in EU-Russia cooperation. New Materials and Nanotechnologies (~ 40% of the Russian funds) (http://cordis.europa.eu/fp7/kbbe/interview_en. Life Sciences and Biotechnology – (~25%) html) Energy and Energy Efficiency Rational Nature Use Information and Communication Technologies (ICTs). The second programme is dedicated to the Industrial Development of Nanotechnologies and New Materials. 22
  • 23. EU-Russia Working Group on «Health and Life Sciences» Priorities Co-funded and Coordinated Calls on «Health» Working Group Meeting on «Heath and Life Sciences» at the Federal Agency for Science and Innovation, Moscow, 12-th of March 2009, For more details see, http://www.fasi.gov.ru/news/press-c/1636/ http://www.fasi.gov.ru/news/press- 23
  • 24. EU-Russia Working Group on Agro-Food-Biotech Priorities (Scheme of decision making and basic documents) EU-RF Declaration of Collaboration RF Topics of Interest EU Topics of Interest Mutual Topics of Interest Minutes of WG Meetings Co-funded and Coordinated Calls 24
  • 25. EC-Russia Coordinated Calls in FP7-TP-FABF • Date of publication: 30 November 2007 FP7 Call KBBE-2008-2B • Deadline: 26 February 2008 In Coordination with Russia • Total budget of call FP7-KBBE-2008-2B: 96.85M€ • Indicative budget dedicated to the coordination activity with Russia: 2+2 M€ (EC+Russia contribution) Topic KBBE-2008-3-1-04: Plant-produced vaccines Topic KBBE-2008-3-2-01: Molecular modelling for rational design of industrial enzymes KBBE- Activity 2.3 KBBE- KBBE- Activity 2.2 KBBE- Biotechnologies 17,56 M € Food 25,58 M € KBBE- Activity 2.1 KBBE- KBBE- Activity 2.3 Sustainable Production and Biotechnologies 4 M € Management of Biological Coordinated & co-funded Resources 48,21 M € SCP with Russian participants Activity 2.4 - Network of Third Countries National Information www.cordis.europa.eu/fp7/kbbe/home_en.htm Points 25 Compiled from Dr. Elisabetta BALZI presentation
  • 26. FABF-TP EC-Russia Coordinated Calls Date of publication: 30 November 2007 Deadline: 26 February 2008 Indicative budget: 4 M€ (contribution: 2 M€ Russia +2 M€ EC) Funding Scheme: Small Collaborative Project (SCP) Topic KBBE-2008-3-1-04: Plant-Produced Vaccines (Продуцируемые растениями вакцины) Topic KBBE-2008-3-2-01: Molecular Modelling for Rational Design of Industrial Enzymes (Молекулярное моделирование для рационального дизайна промышленных ферментов) All specific arrangements for this particular Call is set out in the relevant Guide for Applicants 26
  • 27. FABF-TP EC Russia Coordinated Calls KBBE-2008-3-1-04 : Plant - produced Vaccines This project will focus on the development of innovative vaccines using plants as production systems. Plants offer many advantages over current production platforms by combining the benefits of traditional fermentor systems (containment, precise growth conditions) with those of plants (economy, safety, scalability). Specific technologies have been developed recently for the production of high-value recombinant proteins in plants. Remaining bottlenecks for these technologies include low yield of recombinant proteins, high production costs and lengthy development and testing of the plants. The overall aim of the project will be to identify and establish higher antigen yields production systems, which are highly controllable and reproducible. This includes the selection of the most suitable plant species and culture conditions, improved understanding of antigen presentation and immunity, rapid screening and up-scaling, rapid development of vaccine variants and novel technologies for improved vaccine production. Expected impact: High efficiency and low cost production of vaccines. The project is expected to contribute to the "EU-Russia Common Space for Education and Research" and to the S&T bilateral agreement between the European Community and the Russian Federation and to the EU-South Africa dialogue on KBBE on the basis of mutual interest and shared benefits. Scientific Officer: Tomasz Calikowski, email: Tomasz.Calikowski@ec.europa.eu 27
  • 28. FABF-TP EC Russia Coordinated Calls KBBE-2008-3-2-01: Molecular Modelling for Rational Design of Industrial Enzymes Enzymes are increasingly used in the chemical industry. Computational chemistry, bioinformatics, enzyme structure modelling, molecular docking and dynamics, quantum chemistry and corresponding hybrid methods have been developed to describe the intimate details of the bio-catalytic mechanisms. The objective of the topic is to develop rational enzyme design methods based on molecular (in-silico) modelling in order to produce a next generation of highly efficient biocatalysts with an expanded range of substrates, improved enantio-selectivity and enhanced catalytic activity for industrially important conversions. Optimization of multi-enzyme complexes should also be considered. Research should address the development of quantitative parameters which adequately describe the efficiency of the biocatalysts under development. Improved enzymes are particularly required in certain technological areas, such as fine organic synthesis, bio-transformations, biomass conversion and the food industry. Expected impact: Enhance industry's capabilities for rational design of biocatalysts and their fast quantitative evaluation. The project is expected to contribute to the "EU-Russia Common Space for Education and Research" and to the bilateral S&T agreement between the European Community and the Russian Federation, on the basis of mutual interest and 28 shared benefits
  • 29. TP-ENERGY EC-Russia Coordinated Calls Date of publication: 30 November 2007 Deadline: 26 February 2008 Indicative budget: 4 M€ (contribution: 2 M€ Russia +2 M€ EC) Topic ENERGY.2008.2.2.1: Enhancing strategic international cooperation with Russia in the field of power generation from biomass (Производство электроэнергии из биомассы) Topic ENERGY.2008.7.2.3: Innovative operational and monitoring tools for large power systems (Системы управления и оборудование для крупных энергетических сетей) All specific arrangements for this particular Call is set out in the relevant Guide for Applicants 29
  • 30. ENERGY: EC-Russia Coordinated Calls Enhancing strategic international cooperation with Russia in the field of power generation from biomass Content/scope: Research and technology development in the field of power generation from biomass. The co-operation activity should be based on an assessment of ongoing research, the identification of best practices, gaps in knowledge and barriers to implementation in both, the EU and Russia, and propose direction for a collaborative research project in the area. Funding scheme: Collaborative Project (the project duration is normally 3 years) Expected impact: Effective cooperation between key researchers and industries in the field of power generation from biomass should foster the development and uptake of innovative methods and technologies to expand the use of biomass in power generation. 30
  • 31. Indicative Time Table for EC-Russia Coordinated Calls EU Russia Launch of the EC Call 30 November 2007 Launch of the RU Call End of January 2008 Submission deadline EU Call 26 February 2008 Submission Deadline RU Call End of April 2008 Completion of EU evaluation Beginning of April 2008 Completion of RU evaluation Mid of May 2008 End of EU negotiations Mid of July 2008 Signature of EC GA By September 2008 Signature of RU contracts By end of June 2008 Start of projects Starting around the end of 2008 31
  • 32. Call principles for EC-Russia Coordinated Calls SMALL COLLABORATIVE PROJECT Corresponding Joint technical Russian part in Annex Integrated the joint project Min. 2 RU activities Min. 2-3 MS participants or AS participants Submission Submission of of tender to a Joint the Russian < 5% All proposals to Call RU of TEC participants FP7 EU-Russia according to participants sign the EU Call according FASI rules sign a FP7 GA contract to FP7 rules with FASI FASI EC Budget: Budget: Evaluation EC Max. 2M€ Max. 2M€ according RU Evaluation rules EU-RU according concerted dialogue FP7 rules Compiled from presentation of Gilles Lequeux, European Commission, DG Research 32
  • 33. Overview of the Evaluation Process EU-RUSSIA Co-ordinated and Co-funded Projects be ” ay ote M m “re Individual Submission Consensus Panel Finalisation reading Final Evaluators Evaluators Evaluators ranking Full Proposal list Proposal Rejection list Criteria Criteria Criteria forms Proposals in Eligibility suggested priority order COMMISSION COMMISSION Role of experts 33
  • 34. FABF-TP EC Russia Coordinated Calls Minimum Number of Participants: 2 from different EU Member States or FP-Associated Countries* and 2 from different Federal units (provinces, oblasts, republics, territories, districts, Federal cities) from Russia. * FP-Associated Countries: Croatia, Turkey, Serbia, FYROM, Iceland, Israel, Liechtenstein, Norway, Switzerland, and as from 01/01/08 Montenegro and Albania In addition, this research area is particularly well suited for cooperation with other ICPC countries with bilateral S&T agreements with the European Community** such as South Africa, and this will be reflected in the evaluation ** ICPC countries with bilateral S&T agreements with the European Community: Argentina, Brazil, Chile, China, Egypt, India, Mexico, Morocco, Russia, South Africa, Tunisia and Ukraine 34
  • 35. FP7 Funding rules for Collaborative Projects R&D Activities: - EU grant up to 50% of the total eligible cost. - Certain legal entities can receive up to 75% (non-profit public bodies, Small and Medium Size Enterprises / SMEs, higher education establishments). Demonstration Activities: - the reimbursement rate may reach 50% of the total eligible cost. Other activities (consortium management, networking, training, coordination, dissemination etc. ) - the reimbursement can be up to 100% of the eligible cost. 35
  • 36. EU‐RUSSIA Symposia on FP6/7 BIO Priorities Important instruments to strengthen EU‐ Russian сo‐operation in BIO‐TPs of FP7 ‐ I Moscow 2004 ‐ II Moscow  2005 ‐ III St. Petersburg  2006 ‐ IV Suzdal 2007 ‐ V Pushchino                                               2008 ‐ German‐Russian Forum in Moscow     2009 36
  • 37. OUTCOMES of EU-RUSSIA Symposium “Prospects for R&TD Co-operation in Biotechnology in FP7” 5-8 June 2006 St. Petersburg Objectives: Public establishing EU-Russia Working Group on Agro-Food-Biotech priorities Discussion of key issues and prospective of R&TD cooperation between Russia and EU in Biotechnology in FP7 Discussion of Russian participation in FP7 European Technology Platforms Presentation of Russian Technology Platforms 37
  • 38. OUTCOMES of EU-RUSSIA Symposium “Prospects for R&TD Co-operation in Biotechnology in FP7” 5-8 June 2006 St. Petersburg Main results: Adopting Joint Declaration of the EU-Russia Working Group on «Agro-Bio-Food» More than 200 scientists, SME representatives and multipliers from Russia and NIS countries About 50 experts from EU International School of Young Scientists «Biotechnology for the Future» More than 60 young scientists from EU and NIS Brokerage Events and Poster Sections «InJoy&Train» Meeting Posted Catalogue of Profile Forms (119 proposals) for participation in EC FP7 FAFB priorities Russian-German Satellite Symposium on Bioinformatics Network 38
  • 39. Results of 3 First Calls in FP7 EC Funded Projects on FAFB Priorities for 3‐d Countries Participation 11 Projects with Russian Participation 23 Entities from Russia among them: 2 SICA Calls for Russian Participation 2 EU‐Russia Coordinated Projects 2007‐2008 39
  • 40. Russian National Contact Point on «Food, Agriculture, Fisheries & Biotechnology» (Bio-NCP of Russia on FP6-FP7 Programmes of EC) Institute of Biochemistry Thank you for your attention Good Luck in FP7! Vladimir ERYOMIN Scientific Counsellor (Bio-NCP of Russia) Institute of Biochemistry, RAS Leninsky Prospect, 33, 119071 Moscow, RUSSIA Tel.: +7 (495) 954 44 74 eryomin@inbi.ras.ru http://www.fp7-bio.ru 40