Health Sciences South Carolina (HSSC) aims to improve the health of all South Carolinians through collaborative health sciences research, developing innovative health IT infrastructure, and catalyzing economic growth in the state. HSSC works with multiple research centers and hospitals to gather clinical data, identify best practices, and conduct research that benefits patients and leads to new treatments and economic opportunities. The organization strives to foster multidisciplinary research, implement new technologies like electronic health records, and translate scientific discoveries into improved health outcomes and jobs for South Carolinians.

1. Good Health Made Possible
Harnessing the Power of Research
Jay Moskowitz
SmartState James B. Duke Endowed Chair for HealthCare
Quality
President & CEO
Health Sciences South Carolina
Science Café
January 8, 2013

2. The Vision of Health Sciences
South Carolina is to conduct
collaborative health sciences
research to improve the health
status, education, workforce
development and economic well-
being of all South Carolinians.
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3. • Overview Health Sciences South Carolina
• Short & long term objectives of a Unique
Information Technology
• SmartState Centers of Economic Excellence
• Implementing Electronic Health Records
• Innovation for Patient Safety
• Conclusion
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4. 4

5. • The major program of the SmartState Center for HealthCare
Quality is Health Sciences South Carolina (HSSC)
• Established over 8 years ago, the goal of HSSC is, through
research, to improve and safeguard the health of all South
Carolinians
• Reflecting on a central tenet of our American Society, HSSC
fosters the belief in the value and sanctity of the individual
(patient-centered outcomes)
• HSSC is translating The Duke Endowment grants, Federal
grants, partner investments into biomedical discoveries and a
wealth of scientific knowledge that will:
• Improve the process of diagnosis, treatment and prevention
• Establish a unique and innovative infrastructure for twenty-first
century medicine
• Catalyze the creation of skilled jobs and economic productivity
• Accelerate the process of discovery, development, delivery, and
dissemination
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• Benefit all of humanity

6. Improve patient-centered health and
healthcare
• Foster and facilitate a multidisciplinary/multi-
institutional approach to clinical research to
ensure that recent advances in
neurosciences, molecular
biology, genetics, biotechnology are translated to
patients
• Develop new bio-statistical and epidemiological
(population-based) tools with improved outcome
measures and clinical outcomes targets to
enhance research, clinical observations and
patient outcomes
• Establish state-wide/national resources to offer 6
professional and patient guidance in study and

7. Supporting Affiliates
Organizations 7

8. 8

9. Unique and Innovative Infrastructure
• Developed a sound technology architecture and
data management process that delivers real time
protected clinical data and de-identified research
data from participating hospitals and clinics
• Integrates scalable clinical data from multiple
sources for research analytics by
community, region or as a state-wide registry
• Provide data services that include population
health, clinical decision support, comparative
analytics and benchmarking
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13. DATA FLOW AND DATA USAGE
Enterprise CLINICAL
Master Patient GUIDELINES
QUALITY METRICS Index eRX
Death PUBLIC HEALTH
IMPROVED UTILIZATION Registry Reconciliation
STANDARDS
Chronic Disease
Registries Care ACO
Coordination Management
Registry Research
CDW/i2b2
IMPROVED COLLECT AGGREGATE
OUTCOMES PRACTICE CLINICAL
PROVIDER POPULATION TRIALS
POSITIVE PATIENT HEALTH SYSTEM HEALTH
IMPACT CLINICAL
RESEARCH
Standardized GENOMICS
Reporting for
External All Claims Medicare/Medi-
Duplicate
Measures caid Data mart
Service Database and Bl
Reduction Comparative
Clinical Data Mart and Analytics/
Business Intelligence Benchmarking Clinical Decision
Tools Support
ANALYTICS
CLINICAL DECISION SUPPORT
BEST PRACTICES
BUSINESS INTELLIGENCE
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15. Catalyze economic productivity
• Supported the development of 12 SmartState
Centers of Economic Excellence contributing to
the total of over 8,000 high-paid, knowledge
economy jobs created by the program (48
Centers)
• Received over $50 million in grant funding over
the past 6 years (dollars from out-of-state)
• Directly employs over 30 people – (full and part
time)
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16. Centers • Molecular Proteomics
• Health Care Quality for Cardiovascular
• Clinical Effectiveness Disease Prevention
and Patient Safety and Treatment
• Brain Imaging • Regenerative
• Cancer Stem Cell Medicine
Biology and Therapy • SeniorSMART™
• Childhood • Stroke
Neurotherapeutics • Technology Center to
• Health Facilities Design Enhance Healthful
and Testing Lifestyles
• Medication Safety and
Efficacy Investment
• $18 Million
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19. Benefit All Humanity
• The HSSC budget and allocation of resources is
driven by focusing on science opportunities and
health needs of South Carolina and results are
made “portable” to benefit all humankind
• Exemplifying and promoting the highest level of
scientific integrity, public accountability and social
responsibility in what we do and teach this process
to future generations
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20. “To invest in the
infrastructure
necessary to
allow for and
promote the
electronic
exchange and
use of health
information for
each individual
in the United
States.”
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21. • Offer information about the effective strategies and
practices to select, implement, and meaningfully
use certified EHR technology to improve quality and
value of healthcare.
CITIA WILL: • Help in assessing the health IT needs of this
practice and help selecting an EHR vendor product.
• Offer information on a selection of preferred EHR
vendor products vetted by an expert committee and
negotiation of group pricing and purchase contracts
with preferred vendors.
• Help in the EHR implementation process in your
practice, including individualized and on-site
coaching and consultation.
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25. HAI: The Need
Healthcare-Associated Infections are a serious problem:
• Affect ~1 in 20 patients1
• Result in $28B-$45B per year in additional healthcare expenditures2,4
• In 2002 the estimated number of HAIs in U.S. hospitals was estimated to be
1.7M with nearly 100,000 of these HAIs resulting in death.3
• Average cost per HAI ~$20,000 -$26,000.4
• HAI has become such a significant expense that section 5001(c) of the Deficit
Reduction Act states that hospitals will no longer receive reimbursement from
CMS for selected conditions related to HAI, adding significant economic
burden to numerous U.S. hospitals.
• HAIs caused by infectious agents: bacteria, fungi, viruses or other pathogens
• HAIs are associated with a variety of risk factors, including:
• Indwelling medical devices such as bloodstream, endotracheal, and urinary
catheters
• Surgical procedures
• Injections
• Contamination of the healthcare environment
• Transmission of communicable diseases between patients and healthcare
1. http://www.hhs.gov/ash/initiatives/hai/index.html
2.
workers
Hospital acquired infections only: http://www.hhs.gov/ash/initiatives/hai/exec_summary.html
3. • Overuse or improper use of antibiotics
Klevins, et al. “Estimating Health Care-Associated Infections and Deaths in U.S. Hospitals, 2002
4. 25
Scott, “The Direct Medical Costs of Healthcare-Associated Infections in U.S. Hospitals and the Benefits of Prevention,” March 2009

26. HAI: Solutions
Contamination of the healthcare environment and Transmission of
communicable diseases between patients and healthcare workers are two
of the major sources of HAI.1
• Usually addressed by masks, stringent hand washing, and facilities
cleaning protocols
• Highly dependent upon the diligence of those washing their hands and
those cleaning healthcare environment
• Universally applied protocols do not exist for healthcare environment
cleaning
• Hospital privacy curtains have been identified as a significant
source2 and transference mechanism3 for infectious agents
• No recognized protocols for change out or cleaning of privacy
curtains
• There has been a call for new technologies to help prevent
infections, like microbial resistant curtains.4
1. •
http://www.hhs.gov/ash/initiatives/hai/index.html cost effective, better solution than microbial
Clean Shield : a more
2. M. Ohl, et al., , “Hospital Privacy Curtains are Frequently and Rapidly Contaminated with Potentially Pathogenic Bacteria,” 51st
resistant curtains.
ICAAC, Presentation Number K-1463, Chicago IL, Sept. 19, 2011
3. http://www.cbsnews.com/8301-504763_162-20110737-10391704.html
4. Dr. Peter Pronovost, Professor of Critical Care Medicine at Johns Hopkins University, http://www.cbsnews.com/8301-
504763_162-20110737-10391704.html
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27. Clean Shield…the better solution
• Low cost and cost effective way to
reduce HAI and Contamination
Transference
• Pays for itself: Save $$$ through
reduction of HAIs
• Easy & quick & inexpensive
installation and maintenance
• Intuitive, easy to use
• Fresh, contamination free surface
with each use
• Alerts when maintenance is needed
• A better way to reduce HAI
• Strong and positive Economic
Impact for South Carolina (Almost
$10M over 6 years projected for
USC, CU, MSUC, PH, CMs, GOV’T. 27

28. Clean Shield…the better solution
Patent-Pending, touch point dispenser ensures a clean, contamination free
contact surface with each use of the privacy curtain.
An example:
Clean shield arrives as a box Clean shield dispenser is opened
Clean shield dispenser is easily
installed on a curtain
Goals
• Low cost and cost effective means of
contamination transference
reduction/elimination
• Potential to save $ through reduction of
HAIs
• Easy & quick installation/maintenance
• Easy and intuitive to use
• Fresh, contamination free surface with
each use
Clean shield in Clean shield alerts • Alerts when maintenance is needed
hospital application when attention is
needed
• Other examples covered in patent 28

29. “…to intervene, even briefly, between our fellow
creatures and their suffering or death, is our most
authentic answer to the question of our humanity.”
Howard Sackler,
American Playwright
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