Role of insulin & it's alteration in Diabetes Mellitus

1. Role of insulinand it’s alteration in DM. Prepared by: FahadAlHulaibi King Faisal University College of medicine

2. Role of insulin Insulin is protein hormone,secrated after male by B-cells. Response in rising of blood glucose (glycogenesis). Effect metabolism of CHO, fat & protein. < glucose production & > glucose uptake By translocation GLUT4. Stimulate lipogenesis in liver. And inhabit lipolysis (inhabit fat catabolism).

3. In Dm. In DM, insulin deficiency.. or insulin resistance.. Glucose level will be high. Hyperglycemia. Other complications