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Journal of Medical Case Reports                                                                                                          BioMed Central



Case report                                                                                                                            Open Access
Bouveret's syndrome as an unusual cause of gastric outlet
obstruction: a case report
Deepak Joshi*1, Ali Vosough1, Tom M Raymond2, Chris Fox1 and
Arun Dhiman1

Address: 1Department of Gastroenterology, William Harvey Hospital, Ashford, Kent, UK and 2Department of Surgery, William Harvey Hospital,
Ashford, Kent, UK
Email: Deepak Joshi* - djosh78@hotmail.com; Ali Vosough - alireza_vosough@yahoo.co.uk; Tom M Raymond - tom.raymond@ekht.nhs.uk;
Chris Fox - christopher.fox@ekht.nhs.uk; Arun Dhiman - arun.dhiman@ekht.nhs.uk
* Corresponding author




Published: 30 August 2007                                                     Received: 16 January 2007
                                                                              Accepted: 30 August 2007
Journal of Medical Case Reports 2007, 1:73   doi:10.1186/1752-1947-1-73
This article is available from: http://www.jmedicalcasereports.com/content/1/1/73
© 2007 Joshi et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.




                 Abstract
                 An 83 year old caucasian gentleman presented with vomiting and left sided abdominal pain. A
                 subsequent upper GI endoscopy demonstrated a large smooth mass impacted within the
                 duodenum. A cholecysto-duodenal fistula was discovered at laparotomy, with a large gallstone
                 impacted in the duodenum. A diagnosis of Bouveret's syndrome was made. The management of this
                 rare cause of gastric outlet obstruction is discussed.




Background                                                                     dence of aerobilia or gallstones. A naso-gastric tube was
Gallstones, in the majority of patients remain asympto-                        inserted. The patient subsequently underwent an
matic. The commonest clinical manifestation is biliary                         oesophago-gastro-duodenoscopy (OGD) to exclude pos-
colic. Gallstone ileus occurs when a stone enters the intes-                   sible mechanical obstruction. At OGD, a mass was noted
tinal tract via a cholecysto-enteric fistula. The authors                      beyond the pylorus (Figure 1). In the first part of the duo-
present a case of Bouveret's syndrome, a rare complication                     denum, the large smooth mass was seen occupying the
of gallstone disease and rare cause of gastric outlet                          whole lumen with ulceration of the visible surrounding
obstruction.                                                                   mucosa (Figure 2). The mass was irretrievable endoscopi-
                                                                               cally.
Case presentation
An 83 year old gentleman was admitted with a one week                          Computed tomography (CT) of the abdomen demon-
history of vomiting after eating and left-sided upper quad-                    strated a large calcified mass in the first part of the duode-
rant abdominal pain. There was no history of dysphagia                         num (Figure 3). The patient underwent an open
or weights loss. The patient had suffered a similar episode                    laparotomy where a cholecysto-duodenal fistula was
the year previously which had resolved spontaneously.                          found with a large gallstone impacted in the duodenum.
Abdominal examination was unremarkable. No succes-                             No other synchronous gallstones were discovered. The
sion splash was evident. A full blood count, liver function                    gallstone was irretrievable and therefore a gastro-jejunos-
tests and urea and electrolytes were normal. No free air                       tomy was performed. A diagnosis of Bouveret's syndrome
under the right hemi-diaphragm was noted on a chest                            was made.
radiograph. A plain abdominal film was negative for evi-


                                                                                                                                         Page 1 of 3
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Journal of Medical Case Reports 2007, 1:73                                http://www.jmedicalcasereports.com/content/1/1/73




Figure the
bulb
View at 1 pylorus, demonstrating a mass in the duodenal
View at the pylorus, demonstrating a mass in the duodenal
bulb.                                                            Figure 3
                                                                 Abdominal CT demonstrating a calcified mass in duodenum
                                                                 Abdominal CT demonstrating a calcified mass in duodenum.

Post operatively the patient continued to produce large
gastric aspirates via a naso-gastric tube. A repeat OGD          spontaneously. Obstruction most commonly occurs in
demonstrated that both afferent and efferent loops were          the terminal ileum (90%) and less often in the duodenum
patent. The large gallstone was noted once again but this        (3%) [2]. The differential diagnosis of gastric outlet
time in the second part of the duodenum. The patient             obstruction includes diverticulae, foreign bodies, fibrotic
returned to theatre where this time the gallstone (Figure        ulcers and neoplasia Gastric outlet obstruction secondary
4) was successfully milked into the distal jejunum and           to an impacted gallstone in the pyloric region or duodenal
removed via an enterotomy. The patient made an une-              bulb is known as Bouveret's syndrome. More common in
ventful recovery.                                                elderly women, Bouveret's syndrome presents with a non
                                                                 specific triad of epigastric pain, nausea and vomiting.
Case discussion                                                  Abdominal and chest radiographs should be performed
Gallstone ileus is rare [1]. The majority of gallstones that     looking for evidence of aerobilia, bowel obstruction and
enter the GI tract via a cholecysto-enteric fistula are passed   ectopic gallstones. Abdominal CT should also be per-




Figure 2
associated ulceration
A large smooth mass in the first part of the duodenum with
A large smooth mass in the first part of the duodenum with       Figure 4
                                                                 Removed gallstone
associated ulceration.                                           Removed gallstone.




                                                                                                                      Page 2 of 3
                                                                                              (page number not for citation purposes)
Journal of Medical Case Reports 2007, 1:73                                              http://www.jmedicalcasereports.com/content/1/1/73



formed. Typical findings on OGD include a dilated stom-
ach and a hard non-fleshy mass at the obstruction [3].

Treatment options include endoscopic and surgical man-
agement. Endoscopic removal should always be
attempted first, but lithotripsy and stone extraction is
rarely successful [4]. Intracorporeal endoscopic electrohy-
draulic lithotripsy has been used successfully in the treat-
ment of Bouveret's syndrome [5] Surgical options include
enterotomy and removal of the stones (enterolithotomy),
enterolithotomy plus cholecystectomy and repair of the
fistula, or gastric bypass surgery. The decision to use min-
imal invasive surgery versus laparotomy should be made
on an individual patient basis and operator experience.
Fistula repair is unnecessary due to spontaneous closure
especially if the cystic duct is patent and no residual stones
are present. Post operative mortality rates are high, and
may reflect the older subgroup of patients affected [6].

Conclusion
The authors present a case of Bouveret's syndrome in an
83 year old gentleman. The diagnosis should be consid-
ered in patients with symptoms of gastric outlet obstruc-
tion with or without a history of gallstones or aerobilia
and typical endoscopic findings of a dilated stomach and
a hard non-fleshy mass at the obstruction.

Competing interests
The author(s) declare that they have no competing inter-
ests.

Authors' contributions
DJ, AV and TR were involved in writing of the case report.
CF and AD were involved in the review and re-writing of
the case report. All five authors were involved in the
patient's care.

Acknowledgements
Written consent was obtained from the patient prior to submission.

References
1.   Bhama JK, Ogren JW, Lee T, Fisher WE: Bouveret's syndrome.
     Surgery 2002, 131:104-5.
2.   Clavien PA, Richon J, Burgan S, Rohner A: Gallstone ileus. Br J Surg
     1990, 77:737-42.
3.   Capell MS, Davis M: Characterisation of Bouveret's syndrome:                    Publish with Bio Med Central and every
     a comprehensive review of 128 cases. Am J Gastro 2006,                         scientist can read your work free of charge
     101(9):2139-46.
4.   Marchall J, Hayton S: Bouveret's syndrome. The American Journal            "BioMed Central will be the most significant development for
     of Surgery 2004, 187:547-548.                                              disseminating the results of biomedical researc h in our lifetime."
5.   Huebner ES, DuBois S, Lee SD, Saunders MD: Successful endo-                     Sir Paul Nurse, Cancer Research UK
     scopic treatment of Bouveret's syndrome with Intracorpor-
     eal endoscopic electrohydraulic lithotripsy. Gastrointestinal                 Your research papers will be:
     endoscopy 2007, 66(1):183-184.
                                                                                     available free of charge to the entire biomedical community
6.   Schweiger FJ, Shinder R: Duodenal obstruction by a gallstone
     (Bouveret's syndrome) managed by endoscopic stone                               peer reviewed and published immediately upon acceptance
     extraction: a case report and review. Can J Gastroenterol 1997,                 cited in PubMed and archived on PubMed Central
     11:493-6.
                                                                                     yours — you keep the copyright

                                                                            Submit your manuscript here:                                BioMedcentral
                                                                            http://www.biomedcentral.com/info/publishing_adv.asp




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Bouveret's syndrome as an unusual cause of gastric outlet

  • 1. Journal of Medical Case Reports BioMed Central Case report Open Access Bouveret's syndrome as an unusual cause of gastric outlet obstruction: a case report Deepak Joshi*1, Ali Vosough1, Tom M Raymond2, Chris Fox1 and Arun Dhiman1 Address: 1Department of Gastroenterology, William Harvey Hospital, Ashford, Kent, UK and 2Department of Surgery, William Harvey Hospital, Ashford, Kent, UK Email: Deepak Joshi* - djosh78@hotmail.com; Ali Vosough - alireza_vosough@yahoo.co.uk; Tom M Raymond - tom.raymond@ekht.nhs.uk; Chris Fox - christopher.fox@ekht.nhs.uk; Arun Dhiman - arun.dhiman@ekht.nhs.uk * Corresponding author Published: 30 August 2007 Received: 16 January 2007 Accepted: 30 August 2007 Journal of Medical Case Reports 2007, 1:73 doi:10.1186/1752-1947-1-73 This article is available from: http://www.jmedicalcasereports.com/content/1/1/73 © 2007 Joshi et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract An 83 year old caucasian gentleman presented with vomiting and left sided abdominal pain. A subsequent upper GI endoscopy demonstrated a large smooth mass impacted within the duodenum. A cholecysto-duodenal fistula was discovered at laparotomy, with a large gallstone impacted in the duodenum. A diagnosis of Bouveret's syndrome was made. The management of this rare cause of gastric outlet obstruction is discussed. Background dence of aerobilia or gallstones. A naso-gastric tube was Gallstones, in the majority of patients remain asympto- inserted. The patient subsequently underwent an matic. The commonest clinical manifestation is biliary oesophago-gastro-duodenoscopy (OGD) to exclude pos- colic. Gallstone ileus occurs when a stone enters the intes- sible mechanical obstruction. At OGD, a mass was noted tinal tract via a cholecysto-enteric fistula. The authors beyond the pylorus (Figure 1). In the first part of the duo- present a case of Bouveret's syndrome, a rare complication denum, the large smooth mass was seen occupying the of gallstone disease and rare cause of gastric outlet whole lumen with ulceration of the visible surrounding obstruction. mucosa (Figure 2). The mass was irretrievable endoscopi- cally. Case presentation An 83 year old gentleman was admitted with a one week Computed tomography (CT) of the abdomen demon- history of vomiting after eating and left-sided upper quad- strated a large calcified mass in the first part of the duode- rant abdominal pain. There was no history of dysphagia num (Figure 3). The patient underwent an open or weights loss. The patient had suffered a similar episode laparotomy where a cholecysto-duodenal fistula was the year previously which had resolved spontaneously. found with a large gallstone impacted in the duodenum. Abdominal examination was unremarkable. No succes- No other synchronous gallstones were discovered. The sion splash was evident. A full blood count, liver function gallstone was irretrievable and therefore a gastro-jejunos- tests and urea and electrolytes were normal. No free air tomy was performed. A diagnosis of Bouveret's syndrome under the right hemi-diaphragm was noted on a chest was made. radiograph. A plain abdominal film was negative for evi- Page 1 of 3 (page number not for citation purposes)
  • 2. Journal of Medical Case Reports 2007, 1:73 http://www.jmedicalcasereports.com/content/1/1/73 Figure the bulb View at 1 pylorus, demonstrating a mass in the duodenal View at the pylorus, demonstrating a mass in the duodenal bulb. Figure 3 Abdominal CT demonstrating a calcified mass in duodenum Abdominal CT demonstrating a calcified mass in duodenum. Post operatively the patient continued to produce large gastric aspirates via a naso-gastric tube. A repeat OGD spontaneously. Obstruction most commonly occurs in demonstrated that both afferent and efferent loops were the terminal ileum (90%) and less often in the duodenum patent. The large gallstone was noted once again but this (3%) [2]. The differential diagnosis of gastric outlet time in the second part of the duodenum. The patient obstruction includes diverticulae, foreign bodies, fibrotic returned to theatre where this time the gallstone (Figure ulcers and neoplasia Gastric outlet obstruction secondary 4) was successfully milked into the distal jejunum and to an impacted gallstone in the pyloric region or duodenal removed via an enterotomy. The patient made an une- bulb is known as Bouveret's syndrome. More common in ventful recovery. elderly women, Bouveret's syndrome presents with a non specific triad of epigastric pain, nausea and vomiting. Case discussion Abdominal and chest radiographs should be performed Gallstone ileus is rare [1]. The majority of gallstones that looking for evidence of aerobilia, bowel obstruction and enter the GI tract via a cholecysto-enteric fistula are passed ectopic gallstones. Abdominal CT should also be per- Figure 2 associated ulceration A large smooth mass in the first part of the duodenum with A large smooth mass in the first part of the duodenum with Figure 4 Removed gallstone associated ulceration. Removed gallstone. Page 2 of 3 (page number not for citation purposes)
  • 3. Journal of Medical Case Reports 2007, 1:73 http://www.jmedicalcasereports.com/content/1/1/73 formed. Typical findings on OGD include a dilated stom- ach and a hard non-fleshy mass at the obstruction [3]. Treatment options include endoscopic and surgical man- agement. Endoscopic removal should always be attempted first, but lithotripsy and stone extraction is rarely successful [4]. Intracorporeal endoscopic electrohy- draulic lithotripsy has been used successfully in the treat- ment of Bouveret's syndrome [5] Surgical options include enterotomy and removal of the stones (enterolithotomy), enterolithotomy plus cholecystectomy and repair of the fistula, or gastric bypass surgery. The decision to use min- imal invasive surgery versus laparotomy should be made on an individual patient basis and operator experience. Fistula repair is unnecessary due to spontaneous closure especially if the cystic duct is patent and no residual stones are present. Post operative mortality rates are high, and may reflect the older subgroup of patients affected [6]. Conclusion The authors present a case of Bouveret's syndrome in an 83 year old gentleman. The diagnosis should be consid- ered in patients with symptoms of gastric outlet obstruc- tion with or without a history of gallstones or aerobilia and typical endoscopic findings of a dilated stomach and a hard non-fleshy mass at the obstruction. Competing interests The author(s) declare that they have no competing inter- ests. Authors' contributions DJ, AV and TR were involved in writing of the case report. CF and AD were involved in the review and re-writing of the case report. All five authors were involved in the patient's care. Acknowledgements Written consent was obtained from the patient prior to submission. References 1. Bhama JK, Ogren JW, Lee T, Fisher WE: Bouveret's syndrome. Surgery 2002, 131:104-5. 2. Clavien PA, Richon J, Burgan S, Rohner A: Gallstone ileus. Br J Surg 1990, 77:737-42. 3. Capell MS, Davis M: Characterisation of Bouveret's syndrome: Publish with Bio Med Central and every a comprehensive review of 128 cases. Am J Gastro 2006, scientist can read your work free of charge 101(9):2139-46. 4. Marchall J, Hayton S: Bouveret's syndrome. The American Journal "BioMed Central will be the most significant development for of Surgery 2004, 187:547-548. disseminating the results of biomedical researc h in our lifetime." 5. Huebner ES, DuBois S, Lee SD, Saunders MD: Successful endo- Sir Paul Nurse, Cancer Research UK scopic treatment of Bouveret's syndrome with Intracorpor- eal endoscopic electrohydraulic lithotripsy. Gastrointestinal Your research papers will be: endoscopy 2007, 66(1):183-184. available free of charge to the entire biomedical community 6. Schweiger FJ, Shinder R: Duodenal obstruction by a gallstone (Bouveret's syndrome) managed by endoscopic stone peer reviewed and published immediately upon acceptance extraction: a case report and review. Can J Gastroenterol 1997, cited in PubMed and archived on PubMed Central 11:493-6. yours — you keep the copyright Submit your manuscript here: BioMedcentral http://www.biomedcentral.com/info/publishing_adv.asp Page 3 of 3 (page number not for citation purposes)