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Overview of Michigan State University
Brucellosis Research in Africa
Professor John B. Kaneene
DVM, MPH, PhD, FAES
Center for Comparative Epidemiology
Michigan State University
Workshop: An Integrated Approach to Controlling
Brucellosis in Africa, Addis Ababa, 29-31 January 2013
Ghana
Tanzania
Uganda
2
Countries of Study
 Comparative Study of Brucellosis in Livestock
and Humans in Southwestern Uganda
 Collaborating Universities
Michigan State University, College of Veterinary
Medicine
 Prof. John B. Kaneene
Makerere University, College of Veterinary
Medicine, Animal Resources, and Biosecurity
 Dr. Jesca L. Nakavuma
3
Research in Uganda
 Comparative Study of Brucellosis in Livestock
and Humans in Southwestern Uganda
 Hypotheses
Brucellosis is prevalent in cattle, goats, and humans in
rural Uganda
Both Brucella abortus and Brucella melitensis are present
in cattle, goats and humans, and is circulating between
cattle and goats
4
Research in Uganda
 Comparative Study of Brucellosis in Livestock
and Humans in Southwestern Uganda
 Hypotheses (cont.)
Human brucellosis is associated with interaction with
infected livestock, and consumption of undercooked dairy
products from infected livestock
5
Research in Uganda
 Comparative Study of Brucellosis in Livestock
and Humans in Southwestern Uganda
 Study Sites
Kiruhura District
Old Bushenyi District
6
Research in Uganda
 The Prevalence of Brucellosis in
Cattle, Goats, and Humans in
Naitolia, Northern Tanzania
 Collaborating Universities
Michigan State University, College of Veterinary
Medicine
 Prof. John B. Kaneene
Sokoine University of Agriculture, School of Veterinary
Medicine
 Dr. S.I Kimera
7
Research in Tanzania
 The Prevalence of Brucellosis in
Cattle, Goats, and Humans in
Naitolia, Northern Tanzania
 Hypotheses
Brucellosis is prevalent in cattle, goats, and humans in
Naitolia and likely higher (15 – 25%) than what has been
reported in many rural communities in East Africa
Both Brucella abortus and Brucella melitensis are present
in cattle, goats, and humans in Naitolia
8
Research in Tanzania
 The Prevalence of Brucellosis in
Cattle, Goats, and Humans in
Naitolia, Northern Tanzania
Study Site
9
Research in Tanzania
 A Comparative Study of Brucellosis in Local and
Imported Cattle Breeds
 Collaborating Universities
Michigan State University, College of Veterinary Medicine
 Prof. John B. Kaneene
University of Ghana, Noguchi Memorial Institute for
Medical Research
 Dr. Benjamin Adu-Addai
 Dr. Dr. E.B.M. Koney
10
Research in Ghana
 Dr. Dalen Agnew
 Dr. Phyllis Addo
 A Comparative Study of Brucellosis in Local
and Imported Cattle Breeds
 Hypothesis
The prevalence of Brucellosis in local breeds of cattle is
higher than in imported breeds, due to differences in
breeding practices
11
Research in Ghana
 A Comparative Study of Brucellosis in Local
and Imported Cattle Breeds
 Study Sites
Village of Apolonia
12
Research in Ghana

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Overview of Michigan State University Brucellosis Research in Africa

  • 1. Overview of Michigan State University Brucellosis Research in Africa Professor John B. Kaneene DVM, MPH, PhD, FAES Center for Comparative Epidemiology Michigan State University Workshop: An Integrated Approach to Controlling Brucellosis in Africa, Addis Ababa, 29-31 January 2013
  • 3.  Comparative Study of Brucellosis in Livestock and Humans in Southwestern Uganda  Collaborating Universities Michigan State University, College of Veterinary Medicine  Prof. John B. Kaneene Makerere University, College of Veterinary Medicine, Animal Resources, and Biosecurity  Dr. Jesca L. Nakavuma 3 Research in Uganda
  • 4.  Comparative Study of Brucellosis in Livestock and Humans in Southwestern Uganda  Hypotheses Brucellosis is prevalent in cattle, goats, and humans in rural Uganda Both Brucella abortus and Brucella melitensis are present in cattle, goats and humans, and is circulating between cattle and goats 4 Research in Uganda
  • 5.  Comparative Study of Brucellosis in Livestock and Humans in Southwestern Uganda  Hypotheses (cont.) Human brucellosis is associated with interaction with infected livestock, and consumption of undercooked dairy products from infected livestock 5 Research in Uganda
  • 6.  Comparative Study of Brucellosis in Livestock and Humans in Southwestern Uganda  Study Sites Kiruhura District Old Bushenyi District 6 Research in Uganda
  • 7.  The Prevalence of Brucellosis in Cattle, Goats, and Humans in Naitolia, Northern Tanzania  Collaborating Universities Michigan State University, College of Veterinary Medicine  Prof. John B. Kaneene Sokoine University of Agriculture, School of Veterinary Medicine  Dr. S.I Kimera 7 Research in Tanzania
  • 8.  The Prevalence of Brucellosis in Cattle, Goats, and Humans in Naitolia, Northern Tanzania  Hypotheses Brucellosis is prevalent in cattle, goats, and humans in Naitolia and likely higher (15 – 25%) than what has been reported in many rural communities in East Africa Both Brucella abortus and Brucella melitensis are present in cattle, goats, and humans in Naitolia 8 Research in Tanzania
  • 9.  The Prevalence of Brucellosis in Cattle, Goats, and Humans in Naitolia, Northern Tanzania Study Site 9 Research in Tanzania
  • 10.  A Comparative Study of Brucellosis in Local and Imported Cattle Breeds  Collaborating Universities Michigan State University, College of Veterinary Medicine  Prof. John B. Kaneene University of Ghana, Noguchi Memorial Institute for Medical Research  Dr. Benjamin Adu-Addai  Dr. Dr. E.B.M. Koney 10 Research in Ghana  Dr. Dalen Agnew  Dr. Phyllis Addo
  • 11.  A Comparative Study of Brucellosis in Local and Imported Cattle Breeds  Hypothesis The prevalence of Brucellosis in local breeds of cattle is higher than in imported breeds, due to differences in breeding practices 11 Research in Ghana
  • 12.  A Comparative Study of Brucellosis in Local and Imported Cattle Breeds  Study Sites Village of Apolonia 12 Research in Ghana