It is estimated that 10 million people are infected with Chagas worlwide. Most of them don't receive appropiate medical care. The Barcelona Institute for Global Health works to reduce the impact of this forgotten disease and to secure adequate treatments for those who suffer this scourge.
3. These diseases, also known as forgotten,
affect the most vulnerable populations who have limited public voice
NTDs have an ENORMOUS
impact on individuals, families
and communities in low-income
countries
4. One in 6 people on the
planet... suffers from
some kind of NTD...”
Joaquim Gascon, Director of the Neglected Tropical Diseases Initiatives, ISGlobal
7. Chagas is caused
by a parasite The Trypanosoma cruzi
(T. cruzi)
and transmitted to people
via the vector insect:
the vinchuca bug or
barbeiro, chinche,
chipo, pito
15. The Chagas Cycle :
TRANSMISSION
ACUTE
PHASE
CHRONIC
PHASE
WITHOUT DIAGNOSIS
OR TREATMENT
2 Months
Period of 20-30 years
without symptoms
25-30%
of those chronically infected develop
heart complications
10-20% of those
chronically infected develop
digestive
complications
60% of those
infected by the T.
cruzi parasite are
asymptomatic
Their entire lives
Vector
Transfusions/
transplants
Congenital
Oral
10,000 deaths from Chagas each
year
16. Economic
Impact
in Latin America:
The World Bank has classified
Chagas disease as one of the
main public health problems of
the Latin America region, where
it is more prevalent than Malaria
or Dengue
In Brasil, absence of workers with Chagas has caused losses of 5.6 million
USD.
752,000 workdays are lost due to premature deaths
There is a loss of 1,200 million USD in productivity within the 7 countries of the
southern cone
Each year:
19. Prevention
& Control
A vaccine to prevent Chagas doesn’t exist. That’s why it is so
important to know the methods of prevention:
Vector Control
Fumigation of houses where there are vinchuca bugs;
Modification and renovation of the house structure;
Conditioning and reordering of the house interior
Transfusion Control
Risk prevention measures for blood banks to eliminate
the transmission of infected blood
Mother-child transmission Control
Protocols for screening pregnant women, diagnosis and
treatment for children.
20. Treatment
ACUTE PHASE CHRONIC PHASE
In adults and children
over one year, the
disease may be cured
if treated within the first
two months of
infection
With specialized attention, patients may
maintain a better quality of life
Although less effective, the treatment helps
stop the development of the disease’s
complications
And in some cases
may be able to
eliminate the
parasite
In children under one
year, treatment results
in a complete cure
21. 2 Medicines
There are only
TO TREAT CHAGAS:
But they’re not perfect:
TREATMENT MUST BE DONE UNDER A
DOCTOR’S SUPERVISION FOR TWO MONTHS
OF LIMITED ACCESS
NOT VERY EFFECTIVE IN THE CHRONIC PHASE
MAY CAUSE SERIOUS ADVERSE SIDE EFFECTS
22. R + D
WITH MORE RESEARCH AND DEVELOPMENT
WE COULD OFFER BETTER:
Medical
Assistance Pharmaceuticals
23. Research & Development
WE NEED MORE
...even though approx.
100 million people are
at risk
Out of the
total 3.063
million US$
only 20 million
are spent on
Chagas
Chagas receives less than
1% of the total budget for the
research of NTD…