I ran this as a 4 hour tutorial at EuroPython 2011 to teach High Performance Python coding. Techniques covered include bottleneck analysis by profiling, bytecode analysis, converting to C using Cython and ShedSkin, use of the numerical numpy library and numexpr, multi-core and multi-machine parallelisation and using CUDA GPUs. Write-up with 49 page PDF report: http://ianozsvald.com/2011/06/29/high-performance-python-tutorial-v0-1-from-my-4-hour-tutorial-at-europython-2011/