3. What I IWill Cover
What Will Cover
1 Enterprise Ireland’s Role
Agenda
2 Support for Industry
3 Support for Start-ups
3
4. Supporting Innovation in Pharma
and Lifesciences
• Innovation-Led High Potential Start-ups
• Client company investment in R&D
• Commercial return from state research
• Collaboration between industry and academia
• Drawdown by industry and academia from FP7 etc
• Seed and Venture Funds
5.
6. Commercialisation Fund
Support for commercialisation of
research from third-level institutions
Commercialisation Fund C Plus
CF feasibility
- Stages/ Go-No Go
Bench Market
Typically 2- 5 YEARS
8. Date for your diary;
Wednesday 28th November
Aviva Stadium
9. Innovation Support for industry
Technology Centres
(~€2 million p.a. over 5 years)
EU FP7, ESA
Industry Led Research projects
(~€2-3 million over 2-3 years)
Innovation Partnerships Collaboration
(up to €300k over 18 months) Complexity
Number
R&D Fund: Small Projects [<€150k] Partners
Large Projects [<€650k]
Innovation Vouchers ( €5K)
Budget
10. Technology Centres
• Irish companies, multinationals, research institutions
• Undertake market-focussed strategic R&D
• Industry led
• Enterprise Ireland and IDA Ireland
Usually based in a University with
support from partner colleges to deliver
on the research needs of the
companies
11. Technology Centres
Biorefining & Bioenergy Food for Health
IT Innovation Manufacturing Research
Applied Nanotechnology Energy Efficiency
Composite Materials International Energy Centre
Microelectronics Learning Innovation
Connected Health
Financial Services
Cloud Computing
Data Analytics
Pharmaceutical Manufacturing
12. Pharmaceutical Manufacturing PMTC
• Improve manufacturing competitiveness of Irish sites and
companies
• Undertake research in advanced manufacturing
technology with application to Irish pharma industry.
• Source additional funding through company projects and
EU programmes .
• Showcase advanced pharmaceutical manufacturing
expertise
• Support academic-industry collaboration
13. Pharmaceutical Manufacturing PMTC
Initial research focus
Process Analytical Technology (PAT) to improve cost
competitiveness through
• Rapid Microbiological assays
• Continuous Processing – as opposed to batch
• Soft sensors for process monitoring and control
• API-Real Time Release
• Packaging/authenticate/trace and security.
Brendan Lawlor, Interim Research Manager
Brendan.Lawlor@Enterprise-Ireland.com
14. Industry-led Research Networks (ILRP)
• Medium-term 'shared agenda' research by groups of
companies
• Research contracted to a publicly-funded research
institution with funding from Enterprise Ireland
Animal Health
Finished Medical Devices & Medical Aids
Diagnostics
15. Innovation Partnerships
• Typically individual collaborative projects between
companies and researchers
• Up to €300k
• Up to 80% funding from Enterprise Ireland
16. R&D Fund
Small company 45%
Medium Company 35%
Large Company 25%
Simplified Application for Small R&D Fund
<€150k
17. So you want to start a technology business;
How can we help?
18. 100 new HPSUs per year,
20% Life-science
Background of Promoters
Other 5%
Serial Promoter
Indigenous
16%
37%
3rd Level 10%
MNC 32%
Most HPSU Entrepreneurs were managers in
Indigenous Companies or Multinationals
22. EI Assistance
The support you can get from us depends on where you
are.
1. Get to Investor Readiness
• Build Business Plan
We’re a
1. Raising investment Development
Agency
2. Growing the Business
23. Get to Investor Readiness
A Range of Supports
Investor Ready Workshops
Mentor
Market information Pitch preparation
New Frontiers Programme Trade Fairs
Seed Capital
Technology Assessment Certification
Innovation Voucher Value Proposition Workshop
Business Angels
Introduction to VCs
Feasibility Study
24. What we look for at Seed Stage
Large Market Opportunity [especially if VC needed]
Barriers to Entry [current, future?]
High Growth, Scalable
25. HPSU Investment
Due Diligence - the Business Plan
• Market Risks
• Execution Risks
• Financial Risks
EI funding depends on exports, jobs & cash
need
EI Investment is in equity [CCRPs]
Minimum of matching external funding
Average initial investment €250k
Our mission We partner with entrepreneurs, Irish businesses, and the research and investment communities to develop Ireland’s international trade, innovation, leadership and competitiveness The ultimate objective is increased exports, employment and prosperity in Ireland.
Driving the establishment of Innovation-Led High Potential Start-ups Stimulating and supporting product and process R&D in EI client companies ultimately leading to export growth Stimulating collaboration between the existing industry base (Overseas and Irish) and Third Level in Ireland and overseas Maximising the drawdown by Irish researchers (industry and academia) from Framework 7 and European Space Agency (ESA) Maximising the commercial return from national investment in state funded research
Collaborate with companies/research institutes Access EU and ESA Research Supports Source / licence new technologies R&D and Innovation Funding Access EU and ESA Research and Innovation Supports Share: Share on facebook Share on twitter More Sharing Services Enterprise Ireland can introduce you to many international programmes that stimulate and improve collaboration between companies in different EU member states. We can also help you to tender for contracts from prestigious EU agencies.
Industry-led research is a collaborative effort, where companies that might ordinarily be competitors agree to share knowledge, risk and the rewards of pooling their research resources. There are two programmes that support industry-led research in Ireland Technology Centres Initiative joint initiative between Enterprise Ireland and IDA Ireland allowing Irish companies and multinationals to work together on research projects in collaboration with research institutions. Technology Centres are collaborative entities established and led by industry. They are resourced by highly-qualified researchers associated with research institutions who are empowered to undertake market focussed strategic R&D for the benefit of industry. For more information, go to Technology Centres Initiative. Industry-led Research Networks Programme (ILRP) This programme supports medium-term 'shared agenda' research activity among groups of companies that could not afford to fund such research on their own. The model used engages a wide spectrum of companies with a common interest. This leads to success because the risks and benefits associated with large research projects are shared as are the skills and knowledge built up through working with academic researchers. Projects generally take between 9 months and 2 years to complete and the research is contracted out to a publicly-funded research institution with significant funding available from Enterprise Ireland. For more information, go to Industry-led Research Networks Programme.
The PMTC will conduct and coordinate research in advanced pharmaceutical manufacturing technologies which have a wide application across the Irish pharmaceutical industry. The PMTC will assist in the coordination and be an easy access point for the Irish pharmaceutical industry to pharmaceutical related research facilities in Ireland including HEI facilities, Institutes and other Research Centres. The PTMC will work closely with other Irish research centres and academic institutions to source additional funding for Pharmaceutical Manufacturing related research through company specific projects, IDA research funding and EU framework programmes . The PTMC will be a one stop shop to showcase advanced pharmaceutical manufacturing expertise and support academic-industry collaboration in relation to advanced pharmaceutical manufacturing technologies and know-how for manufacturing industry and related service providers.
A challenge to a group of Irish based companies to develop a medium term research vision of common commercial interest An opportunity for “self selecting”, interested academic researchers to win funding for executing research projects in response to that vision The research is typically conducted over a 2 year period, and funding is typically in the region of €2M Finished Medical Devices & Medical Aids High tech end-product design, development, manufacture and own IP. This sector has an increasing number of companies in the peripheral-, cardiac- and GI markets which are globally competitive. Many client working with leading academic and clinical expertise and have FDA, NSAI approvals Medical Sub-Supply This sub-sector is experiencing growth at present. Increasing number of precision engineering companies moved into this sub-sector and Companies are backwardly integrating into design and development service and becoming end-to-end ‘solution providers’ rather than component suppliers Diagnostics Genomics, proteomics, microarray, biomarker technology now allow for earlier, faster, more accurate diagnosis
A Small Enterprise is defined as : an enterprise that has fewer than 50 employees and has either an annual turnover and/or an annual Balance Sheet total not exceeding €10m A Medium Sized Enterprise is defined as: an enterprise that has between 50 employees and 249 employees and has either an annual turnover not exceeding €50m or an annual Balance Sheet total not exceeding €43m A large company is a company that employs greater than 250 employees, has either an annual turnover of greater than €50m or an annual balance sheet of greater than €43m.
Projects we invest in Eligible Manufacture or internationally tradable service Management control in Ireland High Potential Usually based on technological innovation Export oriented 10 employees within 3/4 yrs, Sales > €1m [but life-science is different!]
A process to identify entrepreneurs with strong commercial backgrounds An opportunity to link entrepreneurs to the State Funded Research assets with a view to leading new spin outs A connected up strategy within EI to bring several aspects of the organisation to bear on successful cases Commercialisation Specialists Client Knowledge Services High Potential Start-up Unit Investment Services & Growth Capital
Developments in the US have created higher hurdles for Med device companies FDA has made approval process more difficult and less transparent 7 months for a CE approval vs 31 months for FDA Ongoing FDA review of its regulatory process Increase costs , greater uncertainty re approval and reimbursement Europe is seen as a more attractive location for a medical device company CE mark is faster and a more transparent process than FDA Growing reputation in industry Companies get access to EU markets and build commercial and clinical awareness
Don’t need complete teams or even complete plans, but must Identify key technology risks of the project and how to overcome Validate hunches about the market and steps needed Economic benefits if is successful Plan for risk elimination at lowest possible cost .
Commercial opportunity Quality and innovative aspects of the business plan Return to Irish economy (jobs, exports, cost/benefit) Growth potential Level of risk Achievement of previous milestones or Enterprise Ireland investment targets ( for subsequent rounds of funding)
Innovation fund Ireland [additional €250million – half from EI, half from National Pension Reserve Fund] three announced [Polaris Ventures, DJF Esprit, Soffinova Ventures] Tax Based schemes Employment and Investment Incentive Scheme (EII) Max investment in any one company is €10m (max. of €2.5 m in any 12 month period) Income tax relief initially at 30% of amount invested with further 11% tax relief when proven that employment levels have increased by the end of the 3 year holding period. Maximum tax relief in any one tax year is €150,000 Seed Capital Scheme Provides refund (under certain conditions) for PAYE paid over previous 6 years Refund capped on tax actually paid, upper limit on any year of the tax paid on €100k income. Check with your tax advisor and www.revenue.ie