Tuesday, May 20, 2014 | 6:00-9:00 pm Westin Boston Waterfront, Boston, MA This course will reveal design strategies that led to drugs currently in the clinic and on the market. An emphasis will be made on the exploitation of the bioactive ligand conformations using combinations of NMR, X-ray, calculations and SAR. Rational design and the implications of other properties will be addressed which include atropisomer chirality, drug self-aggregation and ADMET. This course will be held prior to the start of the 14th annual “Structure-Based Drug Design (SBDD)” conference being held on May 21-22.

1. Dinner Short Course: Organized by Cambridge Healthtech Institute
Structure- and Dynamics-Based Design Strategies
Tuesday, May 20, 2014 | 6:00-9:00 pm
Westin Boston Waterfront, Boston, MA
This course will reveal design strategies that led to drugs currently in the clinic and on the market. An
emphasis will be made on the exploitation of the bioactive ligand conformations using combinations of
NMR, X-ray, calculations and SAR. Rational design and the implications of other properties will be
addressed which include atropisomer chirality, drug self-aggregation and ADMET. This course will be
held prior to the start of the 14th
annual “Structure-Based Drug Design (SBDD)” conference being held
on May 21-22.
Instructors:
Steven LaPlante, Ph.D., Founder & CEO, NMX Research & Solutions; Adjunct Professor, Institut
National de la Recherche Scientifique (INRS)
Chris Williams, Ph.D., Principal Scientist, Chemical Computing Group
Detailed Agenda:
6:00 Dinner Served
6:15 Strategies for Drug Design Starting from Peptides, HTS Hits and Small-Molecule Fragments
Steven LaPlante, Ph.D., Founder & CEO, NMX Research & Solutions; Adjunct Professor, Institut
National de la Recherche Scientifique (INRS)
7:15 Coffee Break
7:45 Designing Inhibitors with MOE Structure-Based Drug Design Tools
Chris Williams, Ph.D., Principal Scientist, Chemical Computing Group
8:45 Q&A with Speakers
9:00 Close of Course.
How to Register:
Web: https://chidb.com/register/2014/sbd/reg.asp
Call: 781-972-5400
Email: reg@healthtech.com
www.healthtech.com/structure-based-drug-design