1. How does pus spread inside
the tissues?
By:
Calibo, Jansen S.

2. Pus
 Pus is an exudate, typically white-
yellow, yellow, or yellow-
brown, formed at the site of
inflammation during infection.
 An accumulation of pus in an
enclosed tissue space is known as
an abscess, whereas a visible
collection of pus within or beneath
the epidermis is known as a pustule
or pimple.

3.  An abscess (pus accumulation)
develops when the body's immune
system isolates an area of body tissue
that has been infected by an invading
microorganism * (usually bacteria) to
prevent the infection from spreading
further into the body.
 It does this by sending infection-
fighting leukocytes to the infected
area; leukocytes are specialized white
blood cells that can destroy infectious
microorganisms such as
bacteria, parasites, and viruses.

4. As the bacteria and white blood
cells clash at the site of infection:
 Pus begins to form within the
involved tissue.
 As the infection progresses, a wall
of tissue develops surrounding the
infection site.
 This area filled with pus and
becomes inflamed.

5.  When pus spread deeply into soft tissue
rather than exiting through oral or cutaneous
routes, fascial spaces may become involved
following path of least resistance.
 This path of least resistance is the so called
Fistula, the passageway of pus into the
surface. And later on will form boil on the
surface.
 A boil usually starts out within an area of
infection and inflammation.
 The growing pus inside the boil creates
pressure and swelling around the infected
spot, often forming a drainage point at the
surface of the skin called a head.

6. EXAMPLE

7.  Pulpitis >
Necrosis/Progresses
to apex > chronic
inflammation extends
to periapical and
periodontal
ligaments >
granulation tissue >
resorption > area of
inflammation >
formation of fistula >
gum boil