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Neuropathic Pain
  Etiology and Treatment
Pain Concepts
Characteristic    Acute Pain    Chronic Pain


Cause            Generally      Often
                 known          unknown

Duration of      Short, well-  Persists after
                 characterized healing, ≥3
Pain
                               months
Treatment        Underlying     Underlying
approach         disease        disease and
                                pain disorder
Pain Concepts
• Types of Neuropathies
  – Focal
    • Mononeuritis
    • Entrapment
  – Diffuse
    • Proximal
    • Distal
       – Large fiber
       – Small fiber
Pain Concepts
• Problems in Neuropathic Pain
  – Many patient with neuropathic pain
    continue to suffer, despite optimal therapy
  – Development of rationally based, novel
    treatments has been slow
  – Neural mechanism for ‘pain’ is unproven
    for the common syndromes (DM Peripheral
    neuropathy/Postherpetic neuralgia)
Thank You

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Neuropathic Pain Lecture

  • 1. Neuropathic Pain Etiology and Treatment
  • 2. Pain Concepts Characteristic Acute Pain Chronic Pain Cause Generally Often known unknown Duration of Short, well- Persists after characterized healing, ≥3 Pain months Treatment Underlying Underlying approach disease disease and pain disorder
  • 3. Pain Concepts • Types of Neuropathies – Focal • Mononeuritis • Entrapment – Diffuse • Proximal • Distal – Large fiber – Small fiber
  • 4. Pain Concepts • Problems in Neuropathic Pain – Many patient with neuropathic pain continue to suffer, despite optimal therapy – Development of rationally based, novel treatments has been slow – Neural mechanism for ‘pain’ is unproven for the common syndromes (DM Peripheral neuropathy/Postherpetic neuralgia)
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