07 pathogenicity and_virulence

Institute for Microbiology, Medical Faculty of Masaryk University and St. Anna Faculty Hospital in Brno Miroslav Votava, Vladana Woznicová PATHOGENICITY AND VIRULENCE Lecture for 2nd-year students March 3 0 , 200 9

Pathogenicity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Ecological remark ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Infection ,[object Object],[object Object],[object Object]

History of infectious diseases ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Koch´s postulates ,[object Object],[object Object],[object Object],[object Object],[object Object]

Relationship between the microbe and the host ,[object Object],[object Object],[object Object],[object Object],[object Object]

Pathogenicity ,[object Object],[object Object],[object Object]

Primary and opportune pathogens ,[object Object],[object Object],[object Object],[object Object]

Natural and experimental pathogenicity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Opportunistic pathogens – I ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

S. aureus bacteria escaping destruction by human white blood cells http://www3.niaid.nih.gov http://www.podiatrytoday.com

Opportunistic pathogens – II ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Virulence ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Attenuation ,[object Object],[object Object],[object Object],[object Object],[object Object]

MICROBE obligately opportunistically Species: pathogenic pathogenic non-pathogenic Strain: virulent avirulent Individual: sensitive nonspecifically unresponsive or specifically immune Species: susceptible resistant HOST

Recommended reading material ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

07 pathogenicity and_virulence

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07 pathogenicity and_virulence