This document summarizes various pathologies that can affect the female genital tract, including infections, inflammatory conditions, benign and malignant tumors of the ovaries, fallopian tubes, uterus, cervix, vagina and vulva. It describes common sexually transmitted infections and endogenous infections that can involve the lower or entire genital tract. Causes of female infertility are outlined. Benign and malignant tumor types are enumerated for each organ with a focus on histopathological classification. Pre-malignant conditions like cervical intraepithelial neoplasia are also discussed in relation to HPV infection and progression risk.

1. Female genital tract

6. Causes of female infertility

7. HSV

8. Syphilitic chancre

10. Acute salpingoophoritis

12. PID - torsion

17. Follicle cyst

23. Endometriosis

28. Ovarian tumors

29. Serous cystadenoma

30. Serous cystadenoma

31. Serous papillary cystadenoma

32. Serous papillary tumor of low malignant potential (papillary cystadenoma of borderline malignancy)

37. serous cystadenocarcinoma

39. ovarian adenocarcinoma – stromal invasion

40. Malignant cell clusters in ascites

41. Mucinous cystadenoma

43. Mucinous papillary cystadenoma

52. Mucinous cystic tumor of low malignant potential

58. Embryonal carcinoma

59. Choriocarcinoma

63. Dermoid cyst

70. Granulosa cell tumor

71. Granulosa cell tumor

73. Ovarian fibroma

75. Sertoli-Leydig cell tumor

80. Krukenberg tumor

86. Chronic salpingitis

88. Hydrosalpinx

96. Uterus bicornis

97. Uterus didelphys

98. Uterus unicornis with rudimentary horn

100. Acute endometritis

101. Chronic endometritis

107. Disordered early secretion - ovulation

108. Hypersecretion

109. Stromoglandular dissociation

111. Epithelial changes – metaplasia squamous cell

112. Epithelial changes – metaplasia

113. Epithelial changes – metaplasia

115. Endometrial polyp

116. Endometrial polyp

117. Endometrial polyp

118. Atypical polypoid adenomyoma Mixed tumor, stromal smooth muscle + glands (appearance of complex hyperplasia, epithelial atypias)

120. Adenomyosis

121. Adenomyosis

122. Adenomyosis + leiomyoma

129. Classification of endometrial hyperplasis Simple Complex Atypical (specify architecture: simple or complex)

131. Simple hyperplasia

132. Complex hyperplasia

135. Endometrioid carcinoma

139. Endometrioid. ca – cervical invasion

140. EIN in polyp

143. Metaplastic carcinoma

144. Carcinosarcoma = metaplastic carcinoma

151. ESS - HG

154. Leiomyoma

156. Leiomyosarcoma

158. Adenosarcoma

159. Breast ca metastasis

162. Endocervical polyp

163. Endocervical polyp with squamous metaplasia

165. Sexual activity ↓ HPV exposure ↓ cervical transformation zone ↓ ↓ squamous differentiation glandular ↓ ↓ ↓ CIN low grade high ECCIN, AIS (low- or high-risk HPV) (high-risk HPV) (low- or high-risk HPV) ↓ ↓ ↓ ↓ ↓ ↓ ↓ regression progression progression regression progression (rare) smoking, high parity, oral contraceptives, immunity, time ↓ ↓ ↓ invasive squamous ca invasive adenoca

168. HPV – koilocytosis - LSIL

169. HPV - immunohistochemistry

172. HPV CIN II.

174. Invasive squamous cell carcinoma

178. Cervical squamous cell carcinoma

179. Endocervical (glandular) intraepithelial neoplasia – ECCIN

183. Adenosquamous carcinoma – alcian blue staining

189. vaginal adenosis

196. Extensive HPV condylomatosis

202. Lichen sclerosus

204. Vulvar squamous carcinoma