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Introduction to biophysics of receptors Biophysics of hearing and vestibular sense Lectures on Medical Biophysics Department of Biophysics, Medical Faculty,  Masaryk University in Brno
Lecture outline ,[object Object],[object Object],[object Object],[object Object],[object Object]
Biophysics of  sensory perception ,[object Object],[object Object],[object Object],[object Object]
Categorising receptors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Conversion function of receptors ,[object Object],[object Object],[object Object]
Sensory cell ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Biophysical relation between the stimulus and sensation ,[object Object],[object Object],[object Object],[object Object],[object Object]
Adaptation   ,[object Object],Adaptation time-course.  A - stimulus, B - receptor with slow adaptation, C - receptor with fast adaptation time time time Number of action potentials Stimulus intensity
Biophysics of sound perception ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
M ain characteristics of sound: (tone) pitch, colour and intensity ,[object Object],[object Object],[object Object]
Intensity level ,[object Object],[object Object],[object Object],[object Object]
Loudness, hearing field ,[object Object],[object Object],[object Object],[object Object]
Hearing field Intensity level intensity
Loudness level of some sounds 120 - 130 Jet propulsion 100 - 110 Pneumatic drill 60 - 90 Traffic noise 40 - 60 Normal speech 20 - 30 Forest silence 10 - 20 whispering Loudness level [Ph] Sort of sound
Sound spectrum ,[object Object],[object Object],[object Object],A E I O U ,[object Object]
Biophysical function of  the  ear The ear consists of outer, m i ddle and inner ear. ,[object Object],[object Object],[object Object],[object Object],[object Object]
Lever system of ossicles.   Maleus and incus form an unequal lever (force increases 1,3x). So-called  piston transmission. Protection against strong sounds:  Elastic connection of ossicles and reflex es  of muscles ( m m . stapedius, tensor tympani )  can  attenuate strong sounds by 15 dB.
Mechanism of reception of acoustic signals ,[object Object],[object Object],[object Object],[object Object],[object Object]
Organ of Corti ,[object Object],Lamina spiralis
www.sickkids.on.ca/auditorysciencelab/ pictures1.asp. Pictures obtained from SEM. Organ of Corti with rows of  hair- cells. Above general view after removal of vestibular (Reissner)  and tectorial membrane. Right a detail of  hair- cells.
Organ of Corti ,[object Object],[object Object],[object Object],[object Object]
Mechanism of sound perception: Békésy theory of travelling wave. ,[object Object],[object Object],[object Object]
Electric phenomena in sound reception: ,[object Object],[object Object],[object Object],[object Object],[object Object]
Biophysical function of vestibular system ,[object Object],[object Object]
[object Object],[object Object],Biophysical function of vestibular system
Vestibular  organ ,[object Object]
Function of crists and cupullae ,[object Object],[object Object]
Statoconia membrane in sacculus ,[object Object]
Author:  Vojtěch Mornstein Content collaboration and language revision:  Ivo Hrazdira,  Carmel J. Caruana  Presentation design:  - - - Last revision:  June 2009

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Hearing fin

  • 1. Introduction to biophysics of receptors Biophysics of hearing and vestibular sense Lectures on Medical Biophysics Department of Biophysics, Medical Faculty, Masaryk University in Brno
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  • 13. Hearing field Intensity level intensity
  • 14. Loudness level of some sounds 120 - 130 Jet propulsion 100 - 110 Pneumatic drill 60 - 90 Traffic noise 40 - 60 Normal speech 20 - 30 Forest silence 10 - 20 whispering Loudness level [Ph] Sort of sound
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  • 17. Lever system of ossicles. Maleus and incus form an unequal lever (force increases 1,3x). So-called piston transmission. Protection against strong sounds: Elastic connection of ossicles and reflex es of muscles ( m m . stapedius, tensor tympani ) can attenuate strong sounds by 15 dB.
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  • 20. www.sickkids.on.ca/auditorysciencelab/ pictures1.asp. Pictures obtained from SEM. Organ of Corti with rows of hair- cells. Above general view after removal of vestibular (Reissner) and tectorial membrane. Right a detail of hair- cells.
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  • 29. Author: Vojtěch Mornstein Content collaboration and language revision: Ivo Hrazdira, Carmel J. Caruana Presentation design: - - - Last revision: June 2009