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European Vaccine Markets
November 1, 2010
Countries covered: Europe
The European vaccines market has demonstrated growth even through tough economic
times. This has mainly been due to the introduction of vaccines in untapped disease
markets and government’s acceptance and willingness to pay for new products. This
has encouraged market participants to increase spending in research and development.
This report, European Vaccine Markets, examines the market for vaccines used in
humans for various types of disease. It covers only commercialized vaccines and
developmental vaccines for diseases that are already vaccine-preventable; it does not
cover emerging vaccines for diseases that are not currently vaccine-preventable, such
as Alzheimer’s disease, diabetes, Ebola infection, Epstein-Barr virus (EBV) infection,
ETEC infection, heart attack, Helicobacter pylori infection, multiple sclerosis,
Parkinson’s disease, West Nile virus (WNV) infection, etc.; vaccines that address these
conditions are discussed in Kalorama’s new report, “Emerging Vaccines: The World
Market.” The report includes vaccine market stats for:
Adult Vaccines-Estimates and Forecasts for
o Influenza
o Pneumococcal
o Meningitis/Pneumonia
o DTaP
o Hepatitis
o HPV
o Travel and Endemic
o Others
Pediatric Vaccines-Estimates and Forecasts for:
o Haemophilus influenzae type b (Hib)
o Pneumococcal infection
o Diphtheria
o Tetanus
o Pertussis (whooping cough)
o Hepatitis A and B

2. o Rotavirus
o Polio
o Measles
o Mumps and Rubella
o Varicella (chicken pox)
o Influenza
o Meningitis
o Human papillomavirus (HPV)
o Combination Vaccines
o Others
The report also contains adult and pediatric vaccine regional market shares for the
following countries:
United Kingdom
Germany
Spain
France
Italy
Rest of Europe*
*In this Kalorama Information Report "Rest of Europe" is broken down in the total
market summary (adult and pediatric combined) to include regional market share of the
total European Vaccine market for Benelux, Scandinavia, Switzerland, Russia, Poland,
Balkans, Baltic Countries, Hungary and Other
The report also includes company market shares for European adult and pediatric
vaccine markets, key issues and trend affecting the industry, and detailed profiles of
major vaccine competitors, including:
Bavarian Nordic A/S
Baxter International
Crucell
Emergent Biosolutions
GlaxoSmithKline
Novartis
Pfizer Inc.
Sanofi Pasteur

3. Table of Contents
TABLE OF CONTENTS CHAPTER ONE: EXECUTIVE SUMMARY
THE EUROPEAN VACCINES MARKET
o Scope and Methodology
o Overview
o Pediatric Preventative Vaccines
Adult Preventative Vaccines
Total Market
Issues and Trends
CHAPTER TWO: INTRODUCTION TO VACCINES
A Brief History: The Development of Vaccines
The Immune Response
Mechanism of Action
Types of Vaccines
o Attenuated (Weakened) Live Viruses
o Killed (Inactivated) Viruses
o Toxoid Vaccines
Genetically Engineered/Modified Vaccines
o Subunit Vaccines
o Conjugate Vaccines
o DNA Vaccination
Vaccine Approval Process
CHAPTER THREE: PEDIATRIC PREVENTIVE VACCINES
Introduction
o United Nations Initiatives
Pediatric Vaccine Products
o BCG
o Diphtheria, Tetanus, Pertussis, Hepatitis B and Polio
o Diphtheria
o Pertussis
o Tetanus
o Hepatitis B
o Poliomyelitis
o Haemophilus Influenzae Type B
o Hepatitis A
o Measles, Mumps and Rubella

4. o Measles
o Mumps
o Rubella
o Meningococcal Disease
o Pneumococcal Conjugate
o Rotavirus
o Varicella
Pediatric Vaccines in Development
The European Market for Pediatric Preventive Vaccines
o Total European Market Size and Forecast
o European Market by Product Type
o Haemophilus Influenzae Type B (Hib)
o Pneumococcal
o DTaP
o Hepatitis A & B
o Rotavirus
o Polio
o MMR
o Varicella
o Influenza
o Menigococcal
o HPV
o Combinations
o Others
o Major Manufacturer’s Market Share—Pediatric Vaccines
CHAPTER FOUR: ADULT PREVENTIVE VACCINES
Introduction
Adult Vaccine-Preventable Diseases: Facts and Figures
Recommendations for Adult Immunization
o WHO International Health Regulations
Adult Vaccine Products
o BCG
o Cervical Cancer
o Cholera
o Diphtheria-Tetanus
o Hepatitis
o Hepatitis A
o Hepatitis B
o Influenza
o Pneumococcal Disease
o Rabies
o Shingles
o Typhoid Fever
Adult Vaccines in Development

5. The European Market for Adult Preventive Vaccines
o Total European Market Size and Forecast
o European Market by Product Type
o Influenza
o DTaP Booster
o HPV
o Hepatitis
o Meningitis/Pneumonia
o Travel/Endemic Vaccines
o Others
o Major Manufacturer’s Market Share—Adult Vaccines
CHAPTER FIVE: VACCINES MARKET SUMMARY
Trends Driving the Vaccines Market
Market Size and Forecast
Vaccine Sales by Region
Vaccine Market Competitors
CHAPTER SIX: ISSUES AND TRENDS
Vaccine Safety
o Refusal to Immunize
o Obesity
o World Health Organization
o The Future of Vaccine Safety
Vaccine Shortages
o Financial incentives
o Equitable pricing
o Vaccine stockpiles
o Smallpox
o Tularemia
o Viral Hemorrhagic Fevers
DNA Vaccination
Innovations in Vaccine Delivery Systems
o Edible Vaccines
o Mucosal Delivery
o Intranasal Delivery
o Vaccine Patches
o Vaccine Chips
Innovations in Vaccine Production
o Tobacco Plant
o Insects
o Nanoparticle Systems
CHAPTER SEVEN: COMPANY PROFILES

6. Bavarian Nordic A/S
o History and Lines of Business
o Strategic Alliances
o Vaccine Products
o Financial Information
Baxter International
o History and Lines of Business
o Vaccine Products
o Financial Information
Crucell
o History and Lines of Business
o Strategic Alliances
o Vaccine Products
o Financial Information
Emergent Biosolutions
o History and Lines of Business
o Strategic Acquisition and Alliance
o Vaccine Products
o Financial
GlaxoSmithKline
o History and Lines of Business
o Strategic Alliances
o Vaccine Products
o Financial Information
Novartis
o History and Lines of Business
o Strategic Alliances
o Vaccine Products
o Financial Information
Pfizer Inc.
o History and Lines of Business
o Strategic alliances
o Vaccine Products
o Financial Information
Sanofi Pasteur
o History and Lines of Business
o Strategic Alliances
o Vaccine Products
o Financial Information

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