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Emelie Bahamonde and Marybel Zabel
July 18, 2011
PHC 6000: Managerial Epidemiology
Methicillin-Resistant Staphylococcus Aureus
We did not plagiarized on any aspect of this assignment.
Emelie Bahamonde
Marybel Zabel
Epidemiology
PHC 6000
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Methicillin-Resistant Staphylococcus Aureus (MRSA)
Introduction
Methicillin-Resistant Staphylococcus Aureus, more commonly known as MRSA, is an
infectious disease that emerged due to the over and misuse of the antibiotic known as
“Methicillin”, MRSA is “commonly found on the skin of healthy individuals, but has the
potential to cause serious disease - About 20% of the population are long-term carriers; over
60% may carry S. aureus intermittently - Colonization is more common in people with greater
exposure to microbial agents and compromised immune systems - Colonized people are more
likely to develop infection” (Lesko, 2011).
MRSA Trends
MRSA developed after the introduction of the antibiotic known as “Methicillin”, in
England in 1959. In 1960, the first case of MRSA was detected in Great Britain, and then by
1967 it had spread to Western Europe and Australia through travelers (University of Chicago,
2011).
In 1968, the first outbreak of MRSA hit the United States, at the Boston City Hospital,
Massachusetts. From this point on MRSA spread gradually across the globe affecting hospitals,
prisons, schools, athletic faculties, and through communities, not only in the United State, but
through the globe. In 1982, the first MRSA case through intravenous drug users was reported in
Detroit, Michigan. After the introduction of policies in congress forcing hospitals to take control
of the epidemic, the Hospital-Acquired MRSA (HA-MRSA), began to stabilize; while the
number of Community-Acquired MRSA infections (CA-MRSA) began to increase at
astronomical rates. Data collected by the University of Chicago showed that by the Mid-1990’s
only “scattered reports of CA-MRSA infections in children in the United States” were present,
but after “comparing 2 periods—1993-1995 and 1995-1997—among children with no risk
factors for health care exposure, there was a 25-fold increase in the rate of hospitalizations due to
MRSA” (University of Chicago, 2010); including in 1999 when the first reports of “ healthy,
young children dying from severe MRSA infections” emerged (University of Chicago, 2010).
Surprisingly, until 2008, reporting of MRSA incidents had not been mandatory in most
the United States. Nevertheless, in 2008, many states, including the State of Florida, began
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requiring “labs participating in electronic reporting to submit all positive S. Aureus culture
results” (Lesko, 2011). Unfortunately, until this day reporting is only mandatory by commercial
labs, but not for hospitals or physicians (Lesko, 2011).
In 2009, CA-MRSA started causing “commonly cause infections in health care settings”
(University of Chicago, 2010). “CA-MRSA infections became more common in most U.S. cities,
while CA-MRSA infection and asymptomatic colonization remained less common outside the
U.S” (University of Chicago, 2010).
Since the Florida Department of Health (FLDOH) began requiring the reporting of
positive MRSA cases, the date collected revealed the number of hospitalization in Florida with
MRSA: “50,996 isolates in 2006, 53,131 in 2007, 61,083 in 2008, 63,427 in 2009, and 60,947 in
2010” (Lesko, 2011).
The data showed that the age groups most affected during the 2010 were from
individual’s age 25 to 64 years (44.0%). The age group with the highest proportion of S. aureus
isolates that were MRSA was the 1 to 4 year olds (62.9%). The age groups with the lowest
proportion of S. aureus isolates that were MRSA were the 5 to 14 year olds (45.7%) and the 15
to 24 year olds (47.9%). In all other age groups, the proportion of isolates that were MRSA was
close to 50%. “The proportion of S. Aureus isolates resistant to various antibiotics did not differ
substantially by age group, with a few exceptions” (Lesko, 2011).
In 2007, the county’s most affected by MRSA cases were located in the West and Central
part of Florida, with some high numbers in the counties such as Palm Beach County, Monroe
County, Martin County, and among others; however, Orange county had among the lowest cases
(see Figure 1). By 2010, the data showed that MRSA incidents where highest among Central
Florida counties all the way to West Florida counties; Orange county numbers were among the
highest - 50-60% (Lesko, 2011). (see Figure 2)
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Marybel Zabel
Epidemiology
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In 2010, the Northern part of the state had the highest proportion of S. aureus isolates that
were MRSA (61.1% in the North Central Region, followed by 56.8% in the North West Region
and 56.0% in the North East Region), while the lowest proportion of isolates that were MRSA
was seen in the South East Region (44.9%). Additionally, the data showed that between West
and East Central Florida the total number of MRSA infections in 2010 was equal to 21,922.
Orange County represented 12.93 percent (2,835) of those infected in East/West Central Florida
(Lesko, 2011).
MRSA Risk Factors
One out ten individuals carries MRSA, but the bacterium poses no harm unless it gets
inside the body of an individual (Sheen, 2010). MRSA is highly contagious and can be
transmitted quickly when individuals who have open wounds come in direct contact with
contaminated surfaces or skin-to-skin contact with individuals who are colonized or infected
with MRSA. An individual that is exposed to MRSA, but presents no signs or symptoms of
infection, is categorized as colonized; while an infected individual has all the clinical signs and
symptoms such as: fever, wound drainage, and lesions, such as carbuncles (Petersen, 2009).
There are two types of MRSA infections, with their own set of risk factors: CA-MRSA and HA-
MRSA.
HA-MRSA was first identified in persons in the 1960s and it is acquired in healthcare
settings including long-term care (LTC) facilities. Patients, LTC residents, and healthcare
workers who are at greater risk for acquiring HA-MRSA are show in Table 1 with their specific
risk factors. (see Table 1)
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Marybel Zabel
Epidemiology
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The most common risk factor in patients and LTC residents is having an open wound that
is exposed to MRSA. The patients and LTC residents listed in Table 1 have weaker immune
systems, which therefore increase their likelihood of acquiring a MRSA infection if exposed.
Environmental conditions within healthcare facilities also play great role in the transmission of
MRSA. Healthcare workers who are colonized by MRSA can contribute to the problem if they
do not take precautionary measures.
In a case study by Albrich and Harbarth, MRSA endemic healthcare facilities had high
incidences of being understaffed and overworked, which resulted in low compliance rates for
hand washing protocols and contact precautions guidelines (Albrich & Harbarth, 2008). In a
guideline published by the Society for Healthcare Epidemiology of America (SHEA), it was
shown that equipment, which was touched only by clinicians, was found to be contaminated with
MRSA; consequently, further studies showed that the hands of clinicians were contaminating
hard and soft surfaces within the hospital (Muto et al., 2003). The SHEA guideline also
discussed how the clothes of healthcare workers had been contaminated with MRSA 65% of the
time after “performing routine ‘morning care’ for patients with MRSA in a wound or urine”
(Muto et al., 2003, pp. 366-367).
In LTC facilities, residents live close to each other and share communal spaces such as
the living room, bedrooms, and dining room. A MRSA carrier can contaminate objects that may
harbor MRSA for up to thirty-eight weeks (Sheen, 2010). The equipment that is used for medical
care is also shared within the LTC facilities. This equipment “may serve as a vehicle for
transferring infectious organisms” (Petersen, 2009).
Unlike HA-MRSA, CA-MRSA affects healthy individuals and it is a lot more virulent.
CA-MRSA infections occur outside of healthcare facilities and have different genetic strains.
Individuals who are at greater risk of getting a CA-MRSA infection are individuals who live in
close quarters where such as military personnel, prisoners, residents of college dormitories,
children attending day-care, and residents of homeless shelters (Sheen, 2010). Athletes also have
a greater risk factor for acquiring a CA-MRSA infection due to (a) close contact activities that
have a higher percentage of obtaining an open wound, such wrestling; (b) sharing of
contaminated items, such as towels, razors, gym equipment; and (c) unsanitary conditions or low
personal hygiene (CDC, 2011). These are the known as the 5 C’s: “Crowding, Contact (frequent
Emelie Bahamonde
Marybel Zabel
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skin-to-skin), Compromised skin (cuts/scrapes), Contaminated items and surfaces, and Lack of
Cleanliness” (CDC, 2011).
Environmental conditions that aid in the transmission of the bacterium is a “common”
risk factors of both types of MRSA. With this knowledge, healthcare organizations (HCO) and
the community can identify preventative strategies that will reduce the transmission and
infections rates of MRSA.
Preventive Strategies or Efforts
The study of the effectiveness of preventive strategies worldwide and in the United States
has been limited due to the lack of consistent data. Many studies on MRSA have had conflicting
results, such as effectiveness and efficiency of implementing a complete screening process
during admissions, some experts believe that it should only be implemented in high risk areas,
others believe that it should be implemented when cases occur in the environment (a reactive
approach), others believe the expense is to large in comparison to the benefits (cost-benefit
analysis), while a great majority believe it should be implemented everywhere, because it saves
lives and unnecessary expense in the long-run. However, many studies and journals have
published that “a program of universal surveillance, contact precautions, hand hygiene, and
institutional culture change was associated with a decrease in health care–associated
transmissions of and infections with MRSA” (Barclay, April 2011). MRSA preventive strategies
have evolved since its first appearance across the globe. Many believed that it was an Emergency
Care issue, but since data began emerging, it became clear that preventive measures had to be
taken across the entire healthcare organization, and now within our communities.
Globally, the World Health Organization has been a great influence on the preventive
strategies that many countries worldwide have been implementing in the control of MRSA.
Some of these strategies are: 1) improving antibiotic use in hospitals, by decreasing diagnostic
uncertainty; 2) heightening awareness of the vital role of hospitals in the control of MRSA, by
“Centralization of available laboratory resources in a few selected centers;” (source) 3)
monitoring and reporting of AB susceptibility data (WHOnet); 4) adapting empiric treatment
regimens; 5) reducing hospital stays to the minimum, but without sacrificing quality of care; 6)
improving peri-operative antibiotic prophylaxis (ABP); 7) “Improve antimicrobial prescribing,
through: a) education (pre- and postgraduate), b) practice guidelines, administrative means
Emelie Bahamonde
Marybel Zabel
Epidemiology
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(antibiotic order forms), and c) Feedback to prescribers” (Harbarth, 2010); 8) improving Out-
Patient Use of antibiotic use; 9) promote local guidelines; and 10) improve marketing strategies
to educate public and change consumer expectations (Harbarth, 2010). By 1999, Chile began to
improve on WHO guidelines by “educate physicians & the public, regulating the consumption of
antibiotics, and restrict over-the-counter antibiotic sales” (Harbarth, 2010). In addition, by 2000,
the Korean government implemented a new policy that “prohibited doctors from dispensing and
pharmacists from prescribing drugs by law” (Harbarth, 2010). Figure 4 below provides further
detail of the global compliance of WHO preventive strategies. (see Figure 4)
In the United States, three organizations have led the development of guidelines for
quality control of MRSA outbreaks in the United States. These are a) CDC’s Healthcare
Infection Control Practices Advisory Committee (HICPAC), b) the Society of Healthcare
Epidemiology of America (SHEA), and c) the Association for Professionals in Infection Control
and Epidemiology (APIC). HICPAC and SHEA have many similar guidelines, but differ in that
HICPAC guidelines utilize a two-tier approach. The first tier “includes general recommendations
for all healthcare settings, regardless of the prevalence of MultiDrug-Resistance Organisms
(MDRO) while the second tier includes recommendations for intensified interventions to prevent
MDRO transmission when prevalence is not decreasing despite routine control measures or when
the first case or outbreak of an MDRO is identified in a facility” (Eisenstein & Sanderson, 2008).
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Marybel Zabel
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“APIC’s guide builds upon these documents and provides more detail on how to implement the
strategies outlined in the HICPAC and SHEA guidelines” (Eisenstein & Sanderson, 2008).
These guidelines focus on preventive strategies or efforts through: a) surveillance; b)
hand-hygiene; c) personal protective equipment (PPE) for healthcare personnel; d) gloves; e)
isolation Gowns; f) face protection: masks, goggles, face shields; g) respiratory protection; h)
safe work practices to prevent HCW exposure to bloodborne pathogens; i) prevention of
needlesticks and other sharps-related injuries; j) prevention of mucous membrane contact; k)
precautions during aerosol-generating procedures; l) patient placement; m) chemoprophylaxis; n)
patient-care equipment and instruments/devices; o) care of the environment, and p) among others
(Siegel, Rhinehart, Jackson, Chiarello, 2006).
In the State of Florida, many hospitals have developed and implemented policies and
procedure, in addition to these guidelines in order to reduce the transmission of MRSA, such as
educating staff; however, there is “no systematic information available on what types of
initiatives have been implemented in Florida” (Eisenstein and Sanderson, October 2008). A
survey was conducted between 2007 and 2008, by the Florida Hospital Association, which
concluded that from all the data collected from the responding facilities, 50.8% were in
compliance with HICPAC tier two recommendations and about 53% for SHEA
recommendations, and 63.4% for HICPAC tier one recommendations” (Eisenstein and
Sanderson, October 2008).The recommendation with the most compliance for the State of
Florida was staff education, at 100%. The survey also revealed that the facilities with the most
compliance were those of mid-size (200-299 beds), and those with the least were the “smallest
facilities (<100 beds), and the largest facilities (400+), which were only slightly more compliant
than the smallest facilities” (Eisenstein and Sanderson, October 2008). The survey also revealed
that preventive measures are not being implemented effectively in the smaller facilities, perhaps
due to budget constraints, and in the larger facilities, perhaps due to lack of coordination and
consistency between the systems.
From a CA-MRSA perspective, there is a lack of preventative strategies, especially from
facilities that are at high-risk. There are no mandatory reporting that would allow health agency
or the public to be informed of MRSA incidents in their community. This could be a contributing
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factor to why in 2007 out of the 48,043 cases of hospitalization with positive MRSA in Florida,
34,674 (72%) where diagnosed positive at the emergency room (AHCA, July 2009).
In Central Florida and including Orange County, the preventive guidelines for HA-
MRSA has improved the reduction of MRSA –incidents within the hospital setting, through the
use of HICPAC, SHEA and APIC guidelines; however, the number of CA-Incidents remain on
the rise due to lack of preventive strategies being implemented at a State, Region and County
level. Ms. Catherine Lesko stated in her report that in order to reduce the number of CA-MRSA
incidents three main preventive strategies should be executed: “Primary Prevention Strategy:
Self-enhanced surveillance, Self education on the importance of frequent hand washing and good
hygiene, Prohibit sharing of any personal hygiene items reporting of skin lesions). Secondary
Prevention Strategy: Education of cases on how to contain their infection, Interview cases on
potential sources of infection, including recent hospitalizations, sharing of personal hygiene
items, injection drug use, unauthorized tattooing, participation in contact sports, and exposure to
other people with draining wounds or skin infections. Physician Preventive Contribution
Strategy: Treatment decisions should be made by physicians, and should be customized to
patients needs, taking into consideration all empirical data. We also recommend FDOH requiring
physicians to report any cases of MRSA incidents” (Lesko, 2011).
Additional to this, Florida HCOs are now participating in ongoing survey of MRSA
preventive strategies in collaboration with Florida Hospital Association. The survey analyzes
active surveillance cultures, contact precautions, education, antibiotic utilization, incidence
surveillance, adherence to hygiene protocols, plans, and potential barriers (Eisenstein &
Sanderson, 2006).
Lastly, locally, the Seminole County MRSA Project is working with local HCOs,
Seminole county schools, patients, and the community to address issues relating to MRSA. They
educate on the importance of preventative measures and education geared towards health clubs,
schools, clinics, nursing homes, and local hospitals. This ongoing project will eventually lead to
the reduction of MRSA cases in local hospitals and the community as well as research
opportunities UCF graduate students (The Seminole County Patient Safety Council, 2007).
Emelie Bahamonde
Marybel Zabel
Epidemiology
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Implications for Public Health Interventions
There are various levels of public health interventions that are being implemented in
order to reduce the transmission of MRSA. The patterns, trends, risk factors, and preventive
strategies at the various levels are able to have an impact on the implications of public health
interventions. Globally many countries conduct their own studies on MRSA since the pathogens
are genetically different where they are resistant to different types of antibiotics. The preventive
strategies in other countries also vary. The Netherlands, for example has taken aggressive
screening and infection control measures, which have resulted in MRSA infection rate of 1-3%.
Other European countries, such as Belgium and Denmark, are trying to implement the same
screening and infection control guidelines (Siegel, Rhinehart, Jackson, & Chiarello, 2006).
In the United States, HICPAC lists multiple studies in which seven types of public health
interventions for MRSA prevention are categorized: 1) administrative support, 2) education, 3)
judicious use of antimicrobials, 4) MDRO surveillance, 5) infection control precautions, 6)
environmental measures, and 7) decolonization.
1) Administrative support increases a) implementation, adherence, and feedback of
surveillance programs and infection control programs; b) communication; and c)
collaboration between other parties at the local, state, and national levels (Siegel,
Rhinehart, Jackson, & Chiarello, 2006).
2) Educational public health interventions were noted to have increased the awareness of
infection control issues that in turn decreased transmission rates (Siegel, Rhinehart,
Jackson, & Chiarello, 2006).
3) Public health interventions involving the use of antimicrobials include updating practice
guidelines that limits the use of a) broad spectrum antibiotics, b) limiting the influence of
pharmaceutical companies on the patterns of prescribing medicine, and c) using social
marketing to increase consumer information about antibiotic use Siegel, Rhinehart,
Jackson, & Chiarello, 2006).
4) MDRO surveillance programs have the potential to identify emerging trends and patterns
of MRSA. States are adopting new laws that require the reporting of MDRO infections.
HCOs use various ways to screen their patients such as using risk factors, using lab tests,
Emelie Bahamonde
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and isolation precautions. These interventions were shown to decrease MRSA infection
rates (Siegel, Rhinehart, Jackson, & Chiarello, 2006).
5) Infection control interventions for MRSA patients include standard precautions, contact
precautions, and grouping patients into the same area of a healthcare facility. Implications
for these interventions had mixed results in various research studies and it was shown that
patients who were in isolation for longer periods had higher rates of depression and patient
satisfaction (Siegel, Rhinehart, Jackson, & Chiarello, 2006).
6) Environmental conditions greatly affect the transmission of MDROs. A couple of research
studies were documented to decrease the transmission rate of MRSA and included using
educational tools geared towards the housekeeping staff, increased disinfection of objects
with high rates of contamination, and assigning cleaning teams to high endemic areas.
7) Decolonization of patients before they were admitted to a hospital has proven to eradicate
MRSA colonization, which in turn decreases the infection rate of patients after medical
procedures. HCOs screen patients via risk factors and lab tests, if the test results are
positive, patients are treated with nasal muciprocin, oral antibiotics, and three days of
antimicrobial baths (Siegel, Rhinehart, Jackson, & Chiarello, 2006).
Preventive measures not only have the potential to eliminate MRSA, but also to save lives.
The implications of these measures mean that the additional costs of treating patients with
MRSA would be eliminated. The average cost of non-MRSA hospitalizations in the U.S. is
$33,687, while the average for MRSA hospitalization is $70,644 (110% more); and the ones
picking up the majority of the tab are taxpayers, as 71% ($2.591.292.8886) of MRSA
hospitalization charges where paid by Medicare, Medicaid and other government agencies in
2007 (AHCA, July 2009).
Conclusion
MRSA is a highly infectious disease that is dangerous and prevalent both globally and
locally. Although studies are being conducted and new preventative strategies implemented,
understanding MRSA and how it is evolving will take more resources and commitment from all
health and public organizations. Leaders must put forward preventive measures in an aggressive
proactive approach. Consequently, it will save lives, improve the quality of care and taxpayers
money.
Emelie Bahamonde
Marybel Zabel
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References
AHCA. (July 2009). MRSA in 2007 Florida hospitalizations. Statistical Brief. Florida Center for
Health Information and Policy Analysis. Florida Agency for Health Care Administration
(AHCA). Retrieved July 5, 2011 from URL:
https://floridahealthfinderstore.blob.core.windows.net/documents/researchers/documents/
MRSAbrieffinal.pdf
Albrich, W. C., & Harbarth, S. (2008). Health-care workers: Source, vector, or victim of
MRSA? The Lancet Infectious Diseases, 8(5), 289-301. doi: 10.1016/S0140-
6736(08)61345-8
Barclay, L. (April 2011). MRSA prevention effective in large healthcare system.
MedscapeToday News. Medscape Medical News. Retrieved July 7, 2011 from URL:
http://www.medscape.com/viewarticle/740863
CDC. (2011). MRSA and the workplace. Workplace Safety & Health Topics. NIOSH. Centers
for Disease Control and Prevention (CDC). Retrieved July 1, 2011 from URL:
http://www.cdc.gov/niosh/topics/mrsa/
Eisenstein, L., & Sanderson, R. (October 2008). MRSA Infection Control Practices in Florida
Hospitals in Comparison to Published Guidelines (Tech.) EpiUpdate. Bureau of
Epidemiology. Florida Department of Health. Retrieved July 10, 2011, from Florida
Professionals in Infection Control website:
http://www.flpic.com/MRSA_Infection_Control_Practices_in_Florida_Hospitals_in_Co
mparison_to_Published_Guidelines.pdf
Harbarth, S. (2010). Strategies to control antibiotic resistance (low-and middle-income
countries). Hopitaux Universitaires de Geneva. World Health Organization (WHO).
Retrieved July 12, 2011 from URL:
http://www.who.int/gpsc/5may/news/webinars/ps_webinar_slides_23sept2010.pdf
Lesko, C. (2011, April). A Community Antibiogram for Community-Associated Staphylococcus
Aureus in Florida, 2006-2010 (United States, Florida Department of Health, Bureau of
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Epidemiology). Retrieved July 5, 2011, from
http://www.doh.state.fl.us/disease_ctrl/epi/htopics/anti_res/MRSA_StatewideSummary_
CHDs.pdf
Lesko, C. (2011, April). A community antibiogram for Community-Associated Staphylococcus
Aureus in Florida, 2006-2010. Staphylococcus Aureus. Retrieved July 05, 2011, from
http://www.doh.state.fl.us/Disease_ctrl/epi/htopics/anti_res/Antibiogram_CA-
Saureus_FL06-10.pdf
Muto, C. A., Jernigan, J. A., Ostrowsky, B. E., Richet, H. M., Jarvis, W. R., Boyce, J. M., &
Farr, B. M. (2003). SHEA guidelines for preventing nosocomial transmission of
multidrug-resistant strains of Staphylococcus aureus and Enterococcus. Infection Control
and Hospital Epidemiology, 24(5), 362-378. Retrieved July 6, 2011, from
http://www.shea-online.org/Assets/files/position_papers/SHEA_MRSA_VRE.PDF
Petersen, E. (2009). Ftag 441, infection control. In Infection control for nursing homes: a guide
to government standards. Retrieved July 6, 2011, from
http://www.hcmarketplace.com/supplemental/8274_browse.pdf
The Seminole County Patient Safety Council. (2007, September 28). MRSA committee
report (Rep.). Retrieved July 16, 2011, from
http://scmsociety.typepad.com/patient_safety/files/mrsa_committee_report_092807.pdf
Sheen, B. (2010). MRSA. Detroit, MI: Lucent Books.
Siegel, J. D., Rhinehart, E., Jackson, M., & Chiarello, L. (2006). (Unites States, Centers for
Disease Control and Prevention, Healthcare Infection Control Practices Advisory
Committee). Retrieved July 10, 2011, from
http://www.cdc.gov/ncidod/dhqp/pdf/ar/MDROGuideline2006.pdf
University of Chicago. (2010). MRSA history timeline: The first half century, 1959-2009.
MRSA Research Center. The University of Chicago Medical Center. Retrieved June 27,
2011 from URL: http://mrsa-research-center.bsd.uchicago.edu/timeline.html
Emelie Bahamonde
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Appendix
Benefits
As future healthcare administrators, it is extremely important to learn how to work with
colleagues to reach goals and objectives. Our goal and objective in this case was to a) research
MRSA, b) communicate to each other findings, c) write about MRSA, and d) review each other’s
work to turn in the best MRSA epidemiology paper. Working together we were able to retrieve
more sources of information, especially when either one of us was busy. We were also able to
communicate to each other research findings that we felt were extremely important. When
writing our paper, we were able to correct each other’s errors or make suggestions that would
improve the paper. Working as a team allowed us to have creative ideas on how to increase the
quality on the paper, such as deciding to add CA-MRSA to the paper and adding financial
information on the implications section.
In a world where time is limited, splitting up the sections evenly allowed us to focus our
research on the various sections. Many times, we were both working on paper in the middle of
the night due to our parental, work, and school responsibilities. Because we both understood
each other’s personal life, we were both able to work together well.
Synergy
During the first class meeting, we decided that we wanted to do our epidemiology paper
on MRSA. We had previously worked together on a previous project about hospital-acquired
infections and felt that MRSA was a topic we were familiar with. We quickly turned in our
choice of working together and our topic. We were very excited that we were chosen to write
about the topic as a team. We were familiar with each other’s work and knew each other
strengths and weaknesses.
After receiving notice that we would work together on the topic of MRSA, we talked
about how we would communicate with each other. We decided that we would mainly
communicate by cell phone, text messages, and wiki-spaces. We also agreed that we would take
turns posting the updates on the discussion boards. Working on wiki-spaces was new for the two
of us but we managed to add a page for every section where we inserted our references and any
information. In our early discussions of MRSA, we also agreed to concentrate on HA-MRSA
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since at the time we were not that familiar with the topic. We felt it was important to include CA-
MRSA due to the high transmission rates within the community therefore decided to add it to the
paper.
Early in the semester, Emelie was able to contact Catherine Lesko from the Florida
Department of Health. Catherine was able to provide us with information that she worked on
relating to MRSA and the information greatly enhanced our paper. We were also able to find a
local source who wants to work with UCF graduate students on the topic of MRSA.
Contributions
The epidemiology paper was divided evenly between both team members. We both
reviewed each other’s work and made suggestions for improvements.
 Section 1: Emelie was responsible for researching and writing about the patterns and
trends of MRSA. She was also able to contact Catherine Lesko from FLDOH.
Various figures were added to the paper to add graphical representation of the
information presented.
 Section 2: The research and writing of risk factors was completed by Marybel. Table
1 was created from a variety of references. Wiki-spaces was updated regularly to
show the references that were being used in the writing process. Summaries of the
references were also shown with the appropriate links.
 Section 3: Emelie worked on the MRSA preventive strategies and efforts. Wiki-
spaces were updated with the links that were used on this section.
 Section 4: Marybel was responsible for the research and writing of the implications
for public health interventions. Many of the references that were used were the same
ones that Emelie used in section 3.
 Discussion Board: We both took turns every week posting the progress reports on the
discussion board.
 Miscellaneous: During the review process some of the paragraphs that were written
in Section 1, were shifted into Section 2. Additionally, some paragraphs from Section
4 were shifted into Section 3. We both decided that the paragraphs flowed better in
the sections in which they were ultimately placed.

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MRSA Epidemiology Paper

  • 1. Emelie Bahamonde and Marybel Zabel July 18, 2011 PHC 6000: Managerial Epidemiology Methicillin-Resistant Staphylococcus Aureus We did not plagiarized on any aspect of this assignment.
  • 2. Emelie Bahamonde Marybel Zabel Epidemiology PHC 6000 2 Methicillin-Resistant Staphylococcus Aureus (MRSA) Introduction Methicillin-Resistant Staphylococcus Aureus, more commonly known as MRSA, is an infectious disease that emerged due to the over and misuse of the antibiotic known as “Methicillin”, MRSA is “commonly found on the skin of healthy individuals, but has the potential to cause serious disease - About 20% of the population are long-term carriers; over 60% may carry S. aureus intermittently - Colonization is more common in people with greater exposure to microbial agents and compromised immune systems - Colonized people are more likely to develop infection” (Lesko, 2011). MRSA Trends MRSA developed after the introduction of the antibiotic known as “Methicillin”, in England in 1959. In 1960, the first case of MRSA was detected in Great Britain, and then by 1967 it had spread to Western Europe and Australia through travelers (University of Chicago, 2011). In 1968, the first outbreak of MRSA hit the United States, at the Boston City Hospital, Massachusetts. From this point on MRSA spread gradually across the globe affecting hospitals, prisons, schools, athletic faculties, and through communities, not only in the United State, but through the globe. In 1982, the first MRSA case through intravenous drug users was reported in Detroit, Michigan. After the introduction of policies in congress forcing hospitals to take control of the epidemic, the Hospital-Acquired MRSA (HA-MRSA), began to stabilize; while the number of Community-Acquired MRSA infections (CA-MRSA) began to increase at astronomical rates. Data collected by the University of Chicago showed that by the Mid-1990’s only “scattered reports of CA-MRSA infections in children in the United States” were present, but after “comparing 2 periods—1993-1995 and 1995-1997—among children with no risk factors for health care exposure, there was a 25-fold increase in the rate of hospitalizations due to MRSA” (University of Chicago, 2010); including in 1999 when the first reports of “ healthy, young children dying from severe MRSA infections” emerged (University of Chicago, 2010). Surprisingly, until 2008, reporting of MRSA incidents had not been mandatory in most the United States. Nevertheless, in 2008, many states, including the State of Florida, began
  • 3. Emelie Bahamonde Marybel Zabel Epidemiology PHC 6000 3 requiring “labs participating in electronic reporting to submit all positive S. Aureus culture results” (Lesko, 2011). Unfortunately, until this day reporting is only mandatory by commercial labs, but not for hospitals or physicians (Lesko, 2011). In 2009, CA-MRSA started causing “commonly cause infections in health care settings” (University of Chicago, 2010). “CA-MRSA infections became more common in most U.S. cities, while CA-MRSA infection and asymptomatic colonization remained less common outside the U.S” (University of Chicago, 2010). Since the Florida Department of Health (FLDOH) began requiring the reporting of positive MRSA cases, the date collected revealed the number of hospitalization in Florida with MRSA: “50,996 isolates in 2006, 53,131 in 2007, 61,083 in 2008, 63,427 in 2009, and 60,947 in 2010” (Lesko, 2011). The data showed that the age groups most affected during the 2010 were from individual’s age 25 to 64 years (44.0%). The age group with the highest proportion of S. aureus isolates that were MRSA was the 1 to 4 year olds (62.9%). The age groups with the lowest proportion of S. aureus isolates that were MRSA were the 5 to 14 year olds (45.7%) and the 15 to 24 year olds (47.9%). In all other age groups, the proportion of isolates that were MRSA was close to 50%. “The proportion of S. Aureus isolates resistant to various antibiotics did not differ substantially by age group, with a few exceptions” (Lesko, 2011). In 2007, the county’s most affected by MRSA cases were located in the West and Central part of Florida, with some high numbers in the counties such as Palm Beach County, Monroe County, Martin County, and among others; however, Orange county had among the lowest cases (see Figure 1). By 2010, the data showed that MRSA incidents where highest among Central Florida counties all the way to West Florida counties; Orange county numbers were among the highest - 50-60% (Lesko, 2011). (see Figure 2)
  • 4. Emelie Bahamonde Marybel Zabel Epidemiology PHC 6000 4 In 2010, the Northern part of the state had the highest proportion of S. aureus isolates that were MRSA (61.1% in the North Central Region, followed by 56.8% in the North West Region and 56.0% in the North East Region), while the lowest proportion of isolates that were MRSA was seen in the South East Region (44.9%). Additionally, the data showed that between West and East Central Florida the total number of MRSA infections in 2010 was equal to 21,922. Orange County represented 12.93 percent (2,835) of those infected in East/West Central Florida (Lesko, 2011). MRSA Risk Factors One out ten individuals carries MRSA, but the bacterium poses no harm unless it gets inside the body of an individual (Sheen, 2010). MRSA is highly contagious and can be transmitted quickly when individuals who have open wounds come in direct contact with contaminated surfaces or skin-to-skin contact with individuals who are colonized or infected with MRSA. An individual that is exposed to MRSA, but presents no signs or symptoms of infection, is categorized as colonized; while an infected individual has all the clinical signs and symptoms such as: fever, wound drainage, and lesions, such as carbuncles (Petersen, 2009). There are two types of MRSA infections, with their own set of risk factors: CA-MRSA and HA- MRSA. HA-MRSA was first identified in persons in the 1960s and it is acquired in healthcare settings including long-term care (LTC) facilities. Patients, LTC residents, and healthcare workers who are at greater risk for acquiring HA-MRSA are show in Table 1 with their specific risk factors. (see Table 1)
  • 5. Emelie Bahamonde Marybel Zabel Epidemiology PHC 6000 5 The most common risk factor in patients and LTC residents is having an open wound that is exposed to MRSA. The patients and LTC residents listed in Table 1 have weaker immune systems, which therefore increase their likelihood of acquiring a MRSA infection if exposed. Environmental conditions within healthcare facilities also play great role in the transmission of MRSA. Healthcare workers who are colonized by MRSA can contribute to the problem if they do not take precautionary measures. In a case study by Albrich and Harbarth, MRSA endemic healthcare facilities had high incidences of being understaffed and overworked, which resulted in low compliance rates for hand washing protocols and contact precautions guidelines (Albrich & Harbarth, 2008). In a guideline published by the Society for Healthcare Epidemiology of America (SHEA), it was shown that equipment, which was touched only by clinicians, was found to be contaminated with MRSA; consequently, further studies showed that the hands of clinicians were contaminating hard and soft surfaces within the hospital (Muto et al., 2003). The SHEA guideline also discussed how the clothes of healthcare workers had been contaminated with MRSA 65% of the time after “performing routine ‘morning care’ for patients with MRSA in a wound or urine” (Muto et al., 2003, pp. 366-367). In LTC facilities, residents live close to each other and share communal spaces such as the living room, bedrooms, and dining room. A MRSA carrier can contaminate objects that may harbor MRSA for up to thirty-eight weeks (Sheen, 2010). The equipment that is used for medical care is also shared within the LTC facilities. This equipment “may serve as a vehicle for transferring infectious organisms” (Petersen, 2009). Unlike HA-MRSA, CA-MRSA affects healthy individuals and it is a lot more virulent. CA-MRSA infections occur outside of healthcare facilities and have different genetic strains. Individuals who are at greater risk of getting a CA-MRSA infection are individuals who live in close quarters where such as military personnel, prisoners, residents of college dormitories, children attending day-care, and residents of homeless shelters (Sheen, 2010). Athletes also have a greater risk factor for acquiring a CA-MRSA infection due to (a) close contact activities that have a higher percentage of obtaining an open wound, such wrestling; (b) sharing of contaminated items, such as towels, razors, gym equipment; and (c) unsanitary conditions or low personal hygiene (CDC, 2011). These are the known as the 5 C’s: “Crowding, Contact (frequent
  • 6. Emelie Bahamonde Marybel Zabel Epidemiology PHC 6000 6 skin-to-skin), Compromised skin (cuts/scrapes), Contaminated items and surfaces, and Lack of Cleanliness” (CDC, 2011). Environmental conditions that aid in the transmission of the bacterium is a “common” risk factors of both types of MRSA. With this knowledge, healthcare organizations (HCO) and the community can identify preventative strategies that will reduce the transmission and infections rates of MRSA. Preventive Strategies or Efforts The study of the effectiveness of preventive strategies worldwide and in the United States has been limited due to the lack of consistent data. Many studies on MRSA have had conflicting results, such as effectiveness and efficiency of implementing a complete screening process during admissions, some experts believe that it should only be implemented in high risk areas, others believe that it should be implemented when cases occur in the environment (a reactive approach), others believe the expense is to large in comparison to the benefits (cost-benefit analysis), while a great majority believe it should be implemented everywhere, because it saves lives and unnecessary expense in the long-run. However, many studies and journals have published that “a program of universal surveillance, contact precautions, hand hygiene, and institutional culture change was associated with a decrease in health care–associated transmissions of and infections with MRSA” (Barclay, April 2011). MRSA preventive strategies have evolved since its first appearance across the globe. Many believed that it was an Emergency Care issue, but since data began emerging, it became clear that preventive measures had to be taken across the entire healthcare organization, and now within our communities. Globally, the World Health Organization has been a great influence on the preventive strategies that many countries worldwide have been implementing in the control of MRSA. Some of these strategies are: 1) improving antibiotic use in hospitals, by decreasing diagnostic uncertainty; 2) heightening awareness of the vital role of hospitals in the control of MRSA, by “Centralization of available laboratory resources in a few selected centers;” (source) 3) monitoring and reporting of AB susceptibility data (WHOnet); 4) adapting empiric treatment regimens; 5) reducing hospital stays to the minimum, but without sacrificing quality of care; 6) improving peri-operative antibiotic prophylaxis (ABP); 7) “Improve antimicrobial prescribing, through: a) education (pre- and postgraduate), b) practice guidelines, administrative means
  • 7. Emelie Bahamonde Marybel Zabel Epidemiology PHC 6000 7 (antibiotic order forms), and c) Feedback to prescribers” (Harbarth, 2010); 8) improving Out- Patient Use of antibiotic use; 9) promote local guidelines; and 10) improve marketing strategies to educate public and change consumer expectations (Harbarth, 2010). By 1999, Chile began to improve on WHO guidelines by “educate physicians & the public, regulating the consumption of antibiotics, and restrict over-the-counter antibiotic sales” (Harbarth, 2010). In addition, by 2000, the Korean government implemented a new policy that “prohibited doctors from dispensing and pharmacists from prescribing drugs by law” (Harbarth, 2010). Figure 4 below provides further detail of the global compliance of WHO preventive strategies. (see Figure 4) In the United States, three organizations have led the development of guidelines for quality control of MRSA outbreaks in the United States. These are a) CDC’s Healthcare Infection Control Practices Advisory Committee (HICPAC), b) the Society of Healthcare Epidemiology of America (SHEA), and c) the Association for Professionals in Infection Control and Epidemiology (APIC). HICPAC and SHEA have many similar guidelines, but differ in that HICPAC guidelines utilize a two-tier approach. The first tier “includes general recommendations for all healthcare settings, regardless of the prevalence of MultiDrug-Resistance Organisms (MDRO) while the second tier includes recommendations for intensified interventions to prevent MDRO transmission when prevalence is not decreasing despite routine control measures or when the first case or outbreak of an MDRO is identified in a facility” (Eisenstein & Sanderson, 2008).
  • 8. Emelie Bahamonde Marybel Zabel Epidemiology PHC 6000 8 “APIC’s guide builds upon these documents and provides more detail on how to implement the strategies outlined in the HICPAC and SHEA guidelines” (Eisenstein & Sanderson, 2008). These guidelines focus on preventive strategies or efforts through: a) surveillance; b) hand-hygiene; c) personal protective equipment (PPE) for healthcare personnel; d) gloves; e) isolation Gowns; f) face protection: masks, goggles, face shields; g) respiratory protection; h) safe work practices to prevent HCW exposure to bloodborne pathogens; i) prevention of needlesticks and other sharps-related injuries; j) prevention of mucous membrane contact; k) precautions during aerosol-generating procedures; l) patient placement; m) chemoprophylaxis; n) patient-care equipment and instruments/devices; o) care of the environment, and p) among others (Siegel, Rhinehart, Jackson, Chiarello, 2006). In the State of Florida, many hospitals have developed and implemented policies and procedure, in addition to these guidelines in order to reduce the transmission of MRSA, such as educating staff; however, there is “no systematic information available on what types of initiatives have been implemented in Florida” (Eisenstein and Sanderson, October 2008). A survey was conducted between 2007 and 2008, by the Florida Hospital Association, which concluded that from all the data collected from the responding facilities, 50.8% were in compliance with HICPAC tier two recommendations and about 53% for SHEA recommendations, and 63.4% for HICPAC tier one recommendations” (Eisenstein and Sanderson, October 2008).The recommendation with the most compliance for the State of Florida was staff education, at 100%. The survey also revealed that the facilities with the most compliance were those of mid-size (200-299 beds), and those with the least were the “smallest facilities (<100 beds), and the largest facilities (400+), which were only slightly more compliant than the smallest facilities” (Eisenstein and Sanderson, October 2008). The survey also revealed that preventive measures are not being implemented effectively in the smaller facilities, perhaps due to budget constraints, and in the larger facilities, perhaps due to lack of coordination and consistency between the systems. From a CA-MRSA perspective, there is a lack of preventative strategies, especially from facilities that are at high-risk. There are no mandatory reporting that would allow health agency or the public to be informed of MRSA incidents in their community. This could be a contributing
  • 9. Emelie Bahamonde Marybel Zabel Epidemiology PHC 6000 9 factor to why in 2007 out of the 48,043 cases of hospitalization with positive MRSA in Florida, 34,674 (72%) where diagnosed positive at the emergency room (AHCA, July 2009). In Central Florida and including Orange County, the preventive guidelines for HA- MRSA has improved the reduction of MRSA –incidents within the hospital setting, through the use of HICPAC, SHEA and APIC guidelines; however, the number of CA-Incidents remain on the rise due to lack of preventive strategies being implemented at a State, Region and County level. Ms. Catherine Lesko stated in her report that in order to reduce the number of CA-MRSA incidents three main preventive strategies should be executed: “Primary Prevention Strategy: Self-enhanced surveillance, Self education on the importance of frequent hand washing and good hygiene, Prohibit sharing of any personal hygiene items reporting of skin lesions). Secondary Prevention Strategy: Education of cases on how to contain their infection, Interview cases on potential sources of infection, including recent hospitalizations, sharing of personal hygiene items, injection drug use, unauthorized tattooing, participation in contact sports, and exposure to other people with draining wounds or skin infections. Physician Preventive Contribution Strategy: Treatment decisions should be made by physicians, and should be customized to patients needs, taking into consideration all empirical data. We also recommend FDOH requiring physicians to report any cases of MRSA incidents” (Lesko, 2011). Additional to this, Florida HCOs are now participating in ongoing survey of MRSA preventive strategies in collaboration with Florida Hospital Association. The survey analyzes active surveillance cultures, contact precautions, education, antibiotic utilization, incidence surveillance, adherence to hygiene protocols, plans, and potential barriers (Eisenstein & Sanderson, 2006). Lastly, locally, the Seminole County MRSA Project is working with local HCOs, Seminole county schools, patients, and the community to address issues relating to MRSA. They educate on the importance of preventative measures and education geared towards health clubs, schools, clinics, nursing homes, and local hospitals. This ongoing project will eventually lead to the reduction of MRSA cases in local hospitals and the community as well as research opportunities UCF graduate students (The Seminole County Patient Safety Council, 2007).
  • 10. Emelie Bahamonde Marybel Zabel Epidemiology PHC 6000 10 Implications for Public Health Interventions There are various levels of public health interventions that are being implemented in order to reduce the transmission of MRSA. The patterns, trends, risk factors, and preventive strategies at the various levels are able to have an impact on the implications of public health interventions. Globally many countries conduct their own studies on MRSA since the pathogens are genetically different where they are resistant to different types of antibiotics. The preventive strategies in other countries also vary. The Netherlands, for example has taken aggressive screening and infection control measures, which have resulted in MRSA infection rate of 1-3%. Other European countries, such as Belgium and Denmark, are trying to implement the same screening and infection control guidelines (Siegel, Rhinehart, Jackson, & Chiarello, 2006). In the United States, HICPAC lists multiple studies in which seven types of public health interventions for MRSA prevention are categorized: 1) administrative support, 2) education, 3) judicious use of antimicrobials, 4) MDRO surveillance, 5) infection control precautions, 6) environmental measures, and 7) decolonization. 1) Administrative support increases a) implementation, adherence, and feedback of surveillance programs and infection control programs; b) communication; and c) collaboration between other parties at the local, state, and national levels (Siegel, Rhinehart, Jackson, & Chiarello, 2006). 2) Educational public health interventions were noted to have increased the awareness of infection control issues that in turn decreased transmission rates (Siegel, Rhinehart, Jackson, & Chiarello, 2006). 3) Public health interventions involving the use of antimicrobials include updating practice guidelines that limits the use of a) broad spectrum antibiotics, b) limiting the influence of pharmaceutical companies on the patterns of prescribing medicine, and c) using social marketing to increase consumer information about antibiotic use Siegel, Rhinehart, Jackson, & Chiarello, 2006). 4) MDRO surveillance programs have the potential to identify emerging trends and patterns of MRSA. States are adopting new laws that require the reporting of MDRO infections. HCOs use various ways to screen their patients such as using risk factors, using lab tests,
  • 11. Emelie Bahamonde Marybel Zabel Epidemiology PHC 6000 11 and isolation precautions. These interventions were shown to decrease MRSA infection rates (Siegel, Rhinehart, Jackson, & Chiarello, 2006). 5) Infection control interventions for MRSA patients include standard precautions, contact precautions, and grouping patients into the same area of a healthcare facility. Implications for these interventions had mixed results in various research studies and it was shown that patients who were in isolation for longer periods had higher rates of depression and patient satisfaction (Siegel, Rhinehart, Jackson, & Chiarello, 2006). 6) Environmental conditions greatly affect the transmission of MDROs. A couple of research studies were documented to decrease the transmission rate of MRSA and included using educational tools geared towards the housekeeping staff, increased disinfection of objects with high rates of contamination, and assigning cleaning teams to high endemic areas. 7) Decolonization of patients before they were admitted to a hospital has proven to eradicate MRSA colonization, which in turn decreases the infection rate of patients after medical procedures. HCOs screen patients via risk factors and lab tests, if the test results are positive, patients are treated with nasal muciprocin, oral antibiotics, and three days of antimicrobial baths (Siegel, Rhinehart, Jackson, & Chiarello, 2006). Preventive measures not only have the potential to eliminate MRSA, but also to save lives. The implications of these measures mean that the additional costs of treating patients with MRSA would be eliminated. The average cost of non-MRSA hospitalizations in the U.S. is $33,687, while the average for MRSA hospitalization is $70,644 (110% more); and the ones picking up the majority of the tab are taxpayers, as 71% ($2.591.292.8886) of MRSA hospitalization charges where paid by Medicare, Medicaid and other government agencies in 2007 (AHCA, July 2009). Conclusion MRSA is a highly infectious disease that is dangerous and prevalent both globally and locally. Although studies are being conducted and new preventative strategies implemented, understanding MRSA and how it is evolving will take more resources and commitment from all health and public organizations. Leaders must put forward preventive measures in an aggressive proactive approach. Consequently, it will save lives, improve the quality of care and taxpayers money.
  • 12. Emelie Bahamonde Marybel Zabel Epidemiology PHC 6000 12 References AHCA. (July 2009). MRSA in 2007 Florida hospitalizations. Statistical Brief. Florida Center for Health Information and Policy Analysis. Florida Agency for Health Care Administration (AHCA). Retrieved July 5, 2011 from URL: https://floridahealthfinderstore.blob.core.windows.net/documents/researchers/documents/ MRSAbrieffinal.pdf Albrich, W. C., & Harbarth, S. (2008). Health-care workers: Source, vector, or victim of MRSA? The Lancet Infectious Diseases, 8(5), 289-301. doi: 10.1016/S0140- 6736(08)61345-8 Barclay, L. (April 2011). MRSA prevention effective in large healthcare system. MedscapeToday News. Medscape Medical News. Retrieved July 7, 2011 from URL: http://www.medscape.com/viewarticle/740863 CDC. (2011). MRSA and the workplace. Workplace Safety & Health Topics. NIOSH. Centers for Disease Control and Prevention (CDC). Retrieved July 1, 2011 from URL: http://www.cdc.gov/niosh/topics/mrsa/ Eisenstein, L., & Sanderson, R. (October 2008). MRSA Infection Control Practices in Florida Hospitals in Comparison to Published Guidelines (Tech.) EpiUpdate. Bureau of Epidemiology. Florida Department of Health. Retrieved July 10, 2011, from Florida Professionals in Infection Control website: http://www.flpic.com/MRSA_Infection_Control_Practices_in_Florida_Hospitals_in_Co mparison_to_Published_Guidelines.pdf Harbarth, S. (2010). Strategies to control antibiotic resistance (low-and middle-income countries). Hopitaux Universitaires de Geneva. World Health Organization (WHO). Retrieved July 12, 2011 from URL: http://www.who.int/gpsc/5may/news/webinars/ps_webinar_slides_23sept2010.pdf Lesko, C. (2011, April). A Community Antibiogram for Community-Associated Staphylococcus Aureus in Florida, 2006-2010 (United States, Florida Department of Health, Bureau of
  • 13. Emelie Bahamonde Marybel Zabel Epidemiology PHC 6000 13 Epidemiology). Retrieved July 5, 2011, from http://www.doh.state.fl.us/disease_ctrl/epi/htopics/anti_res/MRSA_StatewideSummary_ CHDs.pdf Lesko, C. (2011, April). A community antibiogram for Community-Associated Staphylococcus Aureus in Florida, 2006-2010. Staphylococcus Aureus. Retrieved July 05, 2011, from http://www.doh.state.fl.us/Disease_ctrl/epi/htopics/anti_res/Antibiogram_CA- Saureus_FL06-10.pdf Muto, C. A., Jernigan, J. A., Ostrowsky, B. E., Richet, H. M., Jarvis, W. R., Boyce, J. M., & Farr, B. M. (2003). SHEA guidelines for preventing nosocomial transmission of multidrug-resistant strains of Staphylococcus aureus and Enterococcus. Infection Control and Hospital Epidemiology, 24(5), 362-378. Retrieved July 6, 2011, from http://www.shea-online.org/Assets/files/position_papers/SHEA_MRSA_VRE.PDF Petersen, E. (2009). Ftag 441, infection control. In Infection control for nursing homes: a guide to government standards. Retrieved July 6, 2011, from http://www.hcmarketplace.com/supplemental/8274_browse.pdf The Seminole County Patient Safety Council. (2007, September 28). MRSA committee report (Rep.). Retrieved July 16, 2011, from http://scmsociety.typepad.com/patient_safety/files/mrsa_committee_report_092807.pdf Sheen, B. (2010). MRSA. Detroit, MI: Lucent Books. Siegel, J. D., Rhinehart, E., Jackson, M., & Chiarello, L. (2006). (Unites States, Centers for Disease Control and Prevention, Healthcare Infection Control Practices Advisory Committee). Retrieved July 10, 2011, from http://www.cdc.gov/ncidod/dhqp/pdf/ar/MDROGuideline2006.pdf University of Chicago. (2010). MRSA history timeline: The first half century, 1959-2009. MRSA Research Center. The University of Chicago Medical Center. Retrieved June 27, 2011 from URL: http://mrsa-research-center.bsd.uchicago.edu/timeline.html
  • 14. Emelie Bahamonde Marybel Zabel Epidemiology PHC 6000 14 Appendix Benefits As future healthcare administrators, it is extremely important to learn how to work with colleagues to reach goals and objectives. Our goal and objective in this case was to a) research MRSA, b) communicate to each other findings, c) write about MRSA, and d) review each other’s work to turn in the best MRSA epidemiology paper. Working together we were able to retrieve more sources of information, especially when either one of us was busy. We were also able to communicate to each other research findings that we felt were extremely important. When writing our paper, we were able to correct each other’s errors or make suggestions that would improve the paper. Working as a team allowed us to have creative ideas on how to increase the quality on the paper, such as deciding to add CA-MRSA to the paper and adding financial information on the implications section. In a world where time is limited, splitting up the sections evenly allowed us to focus our research on the various sections. Many times, we were both working on paper in the middle of the night due to our parental, work, and school responsibilities. Because we both understood each other’s personal life, we were both able to work together well. Synergy During the first class meeting, we decided that we wanted to do our epidemiology paper on MRSA. We had previously worked together on a previous project about hospital-acquired infections and felt that MRSA was a topic we were familiar with. We quickly turned in our choice of working together and our topic. We were very excited that we were chosen to write about the topic as a team. We were familiar with each other’s work and knew each other strengths and weaknesses. After receiving notice that we would work together on the topic of MRSA, we talked about how we would communicate with each other. We decided that we would mainly communicate by cell phone, text messages, and wiki-spaces. We also agreed that we would take turns posting the updates on the discussion boards. Working on wiki-spaces was new for the two of us but we managed to add a page for every section where we inserted our references and any information. In our early discussions of MRSA, we also agreed to concentrate on HA-MRSA
  • 15. Emelie Bahamonde Marybel Zabel Epidemiology PHC 6000 15 since at the time we were not that familiar with the topic. We felt it was important to include CA- MRSA due to the high transmission rates within the community therefore decided to add it to the paper. Early in the semester, Emelie was able to contact Catherine Lesko from the Florida Department of Health. Catherine was able to provide us with information that she worked on relating to MRSA and the information greatly enhanced our paper. We were also able to find a local source who wants to work with UCF graduate students on the topic of MRSA. Contributions The epidemiology paper was divided evenly between both team members. We both reviewed each other’s work and made suggestions for improvements.  Section 1: Emelie was responsible for researching and writing about the patterns and trends of MRSA. She was also able to contact Catherine Lesko from FLDOH. Various figures were added to the paper to add graphical representation of the information presented.  Section 2: The research and writing of risk factors was completed by Marybel. Table 1 was created from a variety of references. Wiki-spaces was updated regularly to show the references that were being used in the writing process. Summaries of the references were also shown with the appropriate links.  Section 3: Emelie worked on the MRSA preventive strategies and efforts. Wiki- spaces were updated with the links that were used on this section.  Section 4: Marybel was responsible for the research and writing of the implications for public health interventions. Many of the references that were used were the same ones that Emelie used in section 3.  Discussion Board: We both took turns every week posting the progress reports on the discussion board.  Miscellaneous: During the review process some of the paragraphs that were written in Section 1, were shifted into Section 2. Additionally, some paragraphs from Section 4 were shifted into Section 3. We both decided that the paragraphs flowed better in the sections in which they were ultimately placed.