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How to manage PCV2  in gilts? Dr Jean-Bernard HERIN,  Avian and Swine technical and marketing manager Dr Guillaume PERREUL, Swine technical  manager
Agenda ,[object Object],[object Object],[object Object],[object Object],[object Object]
Material and methods ,[object Object],[object Object],[object Object],[object Object],[object Object]
ELISA PCV2 SYNBIOTICS and interpretation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Forum d’Athènes
ELISA PCV2 SYNBIOTICS:  What kind of applications? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Forum d’Athènes
Results: company A 125 102 141 42 52 62 SD (%) 3163 4673 1624 11144 240 2077 PCV2 ELISA titre A6 A5 A4 A3 A2 A1 Farm
Results : company P 84 66 59 146 34 78 100 73 191 123 SD (%) 3145 6592 2429 1014 300 1216 100 1712 585 840 PCV2 ELISA titre P10 P9 P8 P7 P6 P5 P4 P3 P2 P1 Farm
Results: company C 138 139 63 65 66 188 114 144 SD (%) 1022 4457 3003 8949 6592 349 11 327 PCV2 ELISA titre C8 C7 C6 C5 C4 C3 C2 C1 Farm
Results: company D 0 88 104 94 187 SD (%) 15000 48 54 2611 3455 PCV2 ELISA titre D6 D5 D3 D2 D1 Farm
Low and heterogeneous titers: which consequences? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
* 3 fœtuses aborted before necropsy Sow 25 : the lowest titer and the biggest pcv2 contamination in genital tract 1/10 4 1/10 4 1/10 3 1/10 3 1/10 4 1/10 4 1/10 3 1/10 3 1/10 2 - - - - - - - - 1 Foetus and corresponding uterine tract (right) - - - + - - - - 7 Foetus and corresponding uterine tract  (left) - - - - - - - 1/11 - Amniotic fluids (positive/total litter) - - - - - - 3/7 - 10/16 Foetuses (positive/total litter) - - - - + - - - - Cervix - - - / - / - - + Tracheo-bronchial lymph node - - - - - + - - + Uterine right lymph node - - - - - - - - + Uterine left lymph node - - - - - + - - - Tonsil - - - - 28 7 21 - 21 - 35 PCR PCV2 in blood at  D+AI 8 0* 11 0 0 0 7 11 16 Pregnant : YES Pregnant : NO Pregnant : YES Négative sows Infected sows
[object Object],[object Object],[object Object],Pr Hans NAUWYNCK DVM, PhD – Laboratory of Virology –   Faculty of Veterinary Medicine – Ghent University - Belgium What should we do?
Agenda ,[object Object],[object Object],[object Object],[object Object],[object Object]
Vaccination study with Circovac at the experimental station of Guernevez Impact on acclimatization and performances of high health status gilts
[object Object],[object Object],[object Object],Gilt health status in quarantine
Material and methods   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],A B
Results: clinical monitoring in quarantine ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Non vaccinated Nothing Nothing Nothing Nothing Dia (1) Nothing Nothing Nothing 15 B 30 Nothing Anor (1) Nothing Nothing Nothing Nothing Anor (2) Nothing 15 B 29 ND ND ND Nothing Nothing Nothing Nothing Anor (1) 16 B 27 Nothing Anor (1) Nothing Nothing Nothing Nothing Nothing Nothing 18 B 26 Vaccinated 17 20 19 18 18 N Appe (1) Anor (2) Loss of weight Appe (1) Nothing Nothing Appe (2) Anor (3) B 24 Nothing Anor (4) Anor (1) Death (1) Anor (1) Nothing Appe (1) Anor (1) Appe (1) Death (1) H++ (1) Appe (1) B 23 Nothing Nothing Nothing Appe (1) Death (1) Nothing Anor (1) Appe (1) Nothing B 22 Appe (2) Anor (1) Appe (1) 5 Appe (2) Diar (2) Limp (1) 4 Appe (1) Nothing 2 Appe (1) Limp (3)  Appe (1)  Anor (2) 1 Appe(2) Appe (2) Diar (3) Appe (2) Appe (1) Anor (2) B 21 Anor (1) Anor (2) Nothing Appe (3) Anor (1) B 20 7 6 3 0 Week Less clinical signs in quarantine in the vaccinated batches!
Results: ADWG in quarantine Non vaccinated    ≈   325 g/d Vaccinated ≈  439 g/d p < 0,001 Improvement of ADWG of vaccinated gilts!
ADWG 3 weeks after insemination  g/day Better acclimatization of gilts at entry in farm
Results: weight at the first farrowing Weight  (kg) Vaccinated Non  vaccinated p < 0,05 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Total born piglets at 1 st  farrowing Non vaccinated Vaccinated +0.5 total born in  vaccinated group
Conclusion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Improvement all along the gilt life!
Improvement of reproductive parameters of gilts after Circovac vaccination Michel Noirrit DVM - France
Farm description ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Case description ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Case description ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PCV2 Circovac vaccination ,[object Object],[object Object],[object Object],[object Object],[object Object]
Reproductive parameters before and after Circovac Non vaccinated gilts Circovac vaccinated gilts p Gilts (number) 165 165 % return to oestrus 5.1 % 1.8 % 0.125 % abortion (n°) 7.3%  (12) 3.6%  (6) 0.146 % farrowing 83.9 % 90.5 % 0.072 Mummies/litter 0.3 0.3 Stillborn/litter 0.8 0.8 Weaning to Fecundation interval  8.7 days 5.5 days NA
Conception rate of young sows and immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],PCV2 vaccination seems necessary even without clinical signs of PMWS
Agenda ,[object Object],[object Object],[object Object],[object Object],[object Object]
PORFIMAD study ,[object Object],[object Object],[object Object],[object Object],[object Object],28x10 6 /year 18x10 6 /year 0,9x10 6 /year 1,2 10 6  800x10 3 44x10 3
Total born/litter  Born alive/litter Vaccinated Non vaccinated + 0,5   Parity + 0,4 Parity
Conclusion ,[object Object],[object Object],[object Object],[object Object],[object Object]
Discussion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]

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02 perreul relu 13 avril soir

  • 1. How to manage PCV2 in gilts? Dr Jean-Bernard HERIN, Avian and Swine technical and marketing manager Dr Guillaume PERREUL, Swine technical manager
  • 2.
  • 3.
  • 4.
  • 5.
  • 6. Results: company A 125 102 141 42 52 62 SD (%) 3163 4673 1624 11144 240 2077 PCV2 ELISA titre A6 A5 A4 A3 A2 A1 Farm
  • 7. Results : company P 84 66 59 146 34 78 100 73 191 123 SD (%) 3145 6592 2429 1014 300 1216 100 1712 585 840 PCV2 ELISA titre P10 P9 P8 P7 P6 P5 P4 P3 P2 P1 Farm
  • 8. Results: company C 138 139 63 65 66 188 114 144 SD (%) 1022 4457 3003 8949 6592 349 11 327 PCV2 ELISA titre C8 C7 C6 C5 C4 C3 C2 C1 Farm
  • 9. Results: company D 0 88 104 94 187 SD (%) 15000 48 54 2611 3455 PCV2 ELISA titre D6 D5 D3 D2 D1 Farm
  • 10.
  • 11. * 3 fœtuses aborted before necropsy Sow 25 : the lowest titer and the biggest pcv2 contamination in genital tract 1/10 4 1/10 4 1/10 3 1/10 3 1/10 4 1/10 4 1/10 3 1/10 3 1/10 2 - - - - - - - - 1 Foetus and corresponding uterine tract (right) - - - + - - - - 7 Foetus and corresponding uterine tract (left) - - - - - - - 1/11 - Amniotic fluids (positive/total litter) - - - - - - 3/7 - 10/16 Foetuses (positive/total litter) - - - - + - - - - Cervix - - - / - / - - + Tracheo-bronchial lymph node - - - - - + - - + Uterine right lymph node - - - - - - - - + Uterine left lymph node - - - - - + - - - Tonsil - - - - 28 7 21 - 21 - 35 PCR PCV2 in blood at D+AI 8 0* 11 0 0 0 7 11 16 Pregnant : YES Pregnant : NO Pregnant : YES Négative sows Infected sows
  • 12.
  • 13.
  • 14. Vaccination study with Circovac at the experimental station of Guernevez Impact on acclimatization and performances of high health status gilts
  • 15.
  • 16.
  • 17.
  • 18. Results: ADWG in quarantine Non vaccinated ≈ 325 g/d Vaccinated ≈ 439 g/d p < 0,001 Improvement of ADWG of vaccinated gilts!
  • 19. ADWG 3 weeks after insemination g/day Better acclimatization of gilts at entry in farm
  • 20.
  • 21. Total born piglets at 1 st farrowing Non vaccinated Vaccinated +0.5 total born in vaccinated group
  • 22.
  • 23. Improvement of reproductive parameters of gilts after Circovac vaccination Michel Noirrit DVM - France
  • 24.
  • 25.
  • 26.
  • 27.
  • 28. Reproductive parameters before and after Circovac Non vaccinated gilts Circovac vaccinated gilts p Gilts (number) 165 165 % return to oestrus 5.1 % 1.8 % 0.125 % abortion (n°) 7.3% (12) 3.6% (6) 0.146 % farrowing 83.9 % 90.5 % 0.072 Mummies/litter 0.3 0.3 Stillborn/litter 0.8 0.8 Weaning to Fecundation interval 8.7 days 5.5 days NA
  • 29.
  • 30.
  • 31.
  • 32. Total born/litter Born alive/litter Vaccinated Non vaccinated + 0,5 Parity + 0,4 Parity
  • 33.
  • 34.
  • 35.

Notes de l'éditeur

  1. A l’abattoir : ganglions + oviductes ligaturées L’occasion de faire aussi un diagnostic différentiel Virémie truie : détectable sur 4 truies parmi les 6 infectées (donc pas toutes) et que pendant 3 semaines environ Pour lecture de ce tableau : Les colonnes : on voit que dans le groupe témoin, on ne retrouve pas de pcv2 Les lignes : on voit une inconstance dans les zones où pcv2 est retrouvé, mais se dégagent majoritairement : ganglion et fœtus Immunité à évoquer