SlideShare une entreprise Scribd logo
1  sur  43
M.Aqeel Maqsood
Roll# 146
Epidemiology , Etiology and Prevention
of Oral cancer
What is Cancer?
Defined as:_

• An uncontrolled,
uncoordinated, excessive
and abnormal growth of
cells is called cancer.
Benign Vs. Malignant
• Does not spread
• Rarely life threatening
• Can be removed

• Spreads to other parts
of the body
• Life threatening
• Can be removed, but
it may grow back
Types of Cancer
• Benign
• Malignant
– Carcinoma
• epithelial origin
• E.g. squamous cell carcinoma
– Sarcoma
• Mesenchymal origin
Oral cancer

• Defined as:_
Indurated, ulcerated lump or sore that
may or may not be painful and is often
associated cervical lymph adenopathy.
Why is it such an important public
health issue?
• Closely associated with tobacco and alcohol.
• 2nd most common cause of death
• In 2003-according to world health report 7.1
million deaths were reported.
• Estimated 50% increase in death rate in next 20
years.
• In Bangladesh, Sirilanka and Pakistan most
common type of cancer.
• And 1/3rd of all the cancers.
Signs and Symptoms
• Sores that do not heal
within 14 days
• Bleeding in mouth
• Lump in neck
• Earache
• Loose teeth
• Dentures will not fit
well

• Pain or numbness in
mouth
• Difficulty chewing or
swallowing
• Bad breath
• Patches on the lip or
in the mouth that are
red, white, or a
mixture of both
Epidemiology of oral cancer
Host factors
1. Age
– Incidence increases with age.
– 98% cases in the west are over 40yrs old.
– More than 50% of cases include ages above 50yrs.

2. Gender
– Incidence is more in
• Men
• Industrial areas
– Women have more incidence of lip carcinoma
– Men have high incidence of buccal carcinoma

3. Occupation
–

Textile workers and leather industries have high incidence of
buccal cavity and larynx carcinoma.
Host Factors
4. Immunity
– AIDS patients are prone to Kaposi carcinoma.
5. Social Class
6. Custom and habits
7. Race
Agent Factors
• Biological
– HIV
– Candida

• Chemical
– Arsenic,dyes,nickel,chromium

• Mechanical
– Ill fitting dentures
– Sores from jagged teeth
Agent factors
• Nutritional
–
–
–
–
–

Precarcinogens in food
Increase consumption of fat
Deficiency in folic acid
Deficiency of proteins
Increase in red chili
Environmental factors
• Water contamination
• Air pollution
• Geographic variation
– Netherland buccal mucosa
– Switzerland lip and tongue
– Canadian Eskimos salivary glands

• Solar heat
– Prolonged exposure causes melanoma
Etiology
• Due to
–
–
–
–
–
–
–

Tobacco
Unhealthy diet
Alcohol
Physical inactivity
Infection
Nutrients
Physical irritants
Risk Factors
• Tobacco is the main culprit
– Mainly chewing tobacco
– 75% of those diagnosed are tobacco users.

• Alcohol 2nd largest risk factor
• Combination of alcohol and tobacco use
– 15x greater risk for oral cancer

• Excessive sun exposure
– Lip cancer

1/24/2014

Oral Cancer

19
Risk Factors
• X-rays
– Cumulative exposure

• Other biological factors
– Viruses and fungus
– HPV 16
• Main agent in cervical cancer
• Now has been linked to oral cancer

1/24/2014

Oral Cancer

20
Tobacco
• Its an important risk factor of oral cancer.
• 90% of cancers are caused by tobacco
• Tobacco can be broadly classified into smokeless
and smoking forms.
Bidi
• Most popular
form of
tobacco
• Estimated
nictinic
content is
1.7-3mg
Cigar
• Cured
tobacco
wrapped in
dried tobacco
leaves.
Chilum
• Conical clay pipe
for smoking
tobacco
• Filed with coarsely
cut tobacco pieces
• Glowing charcoal
is kept on top of
tobacco
Hookah
• Indinan
origin
• Also
known as
water pipe.
Cigerrete
• 1gram tobacco
cured by sunlight
is coverred by
paper.
• 1-1.4mg Nicotinic
content.
• More common in
urban areas
Paan
• Most common
habit of smokeles
tobacco.
• May also include
•
•
•
•
•

Cardamom
Cocnut
Clove
Sugar
Tobacco wraped
in beetle leave
Snuff
• Finely
powdered air
cured and fire
cured tobacco
leaves.
Mishri
• Prepared by
roasting
tobacco on hot
metal plate then
powdered
• Also used to
clean the teeth
Khaini
• Powdered
sundried
tobacco.
• Simply placed
in mouth and
chewed
Mainpuri
Tobacco
• Ingredients
include
•
•
•
•

Tobacco
Slaked lime
Camphor
cloves
Primary

Program to
educate
adolescence

Program for
tobacco
users

Regular
check up

good oral
hygiene
Secondary

Screening

Referral

Early
detection
Tertiary
• Surgery
• Chemotherapy
– Cytotoxic drugs

• Radiotherapy
What you can do:
•
•
•
•
•

Make yourself aware or your mouth
Stop smoking and drinking excessively
Be informed
Have a good diet and stay healthy
Behavioural modification
Prevention as a dentist
• Regular check up
• Suspected patients be thoroughly checked
• Patient should be educated about the preventive
aspects of oral cancers including
– Behavioral
– Physical
– community
Oral cancer
Oral cancer
Oral cancer

Contenu connexe

Tendances

Management of oral cavity cancer 23072018
Management of oral cavity cancer 23072018Management of oral cavity cancer 23072018
Management of oral cavity cancer 23072018
Varshu Goel
 
Oral cancer pwr.pnt.
Oral cancer pwr.pnt.Oral cancer pwr.pnt.
Oral cancer pwr.pnt.
kamalaiims
 
Overview of head & neck cancer
Overview of head & neck cancerOverview of head & neck cancer
Overview of head & neck cancer
Vinin Narayan
 
Cancer of head & neck - basics
Cancer of head & neck - basicsCancer of head & neck - basics
Cancer of head & neck - basics
Dr. SHEETAL KAPSE
 

Tendances (20)

Oral Cancer
Oral CancerOral Cancer
Oral Cancer
 
Management of oral cavity cancer 23072018
Management of oral cavity cancer 23072018Management of oral cavity cancer 23072018
Management of oral cavity cancer 23072018
 
Oral malignancy
Oral malignancyOral malignancy
Oral malignancy
 
oral cancer
oral cancer oral cancer
oral cancer
 
Oral cancer
Oral cancerOral cancer
Oral cancer
 
Oral precancerous lesions
Oral precancerous lesionsOral precancerous lesions
Oral precancerous lesions
 
Oral cancer
Oral cancerOral cancer
Oral cancer
 
Oral cancer
Oral cancerOral cancer
Oral cancer
 
Oral cancer pwr.pnt.
Oral cancer pwr.pnt.Oral cancer pwr.pnt.
Oral cancer pwr.pnt.
 
Premalignant conditions of oral cavity
Premalignant conditions of oral cavityPremalignant conditions of oral cavity
Premalignant conditions of oral cavity
 
Oral cancer
Oral cancerOral cancer
Oral cancer
 
Salivary gland Tumors
Salivary gland TumorsSalivary gland Tumors
Salivary gland Tumors
 
Cancers of the Oral Cavity
Cancers of the Oral CavityCancers of the Oral Cavity
Cancers of the Oral Cavity
 
Overview of head & neck cancer
Overview of head & neck cancerOverview of head & neck cancer
Overview of head & neck cancer
 
Premalignant condition of oral cavity.pptx
Premalignant condition of oral cavity.pptxPremalignant condition of oral cavity.pptx
Premalignant condition of oral cavity.pptx
 
Oral squamous cell carcinoma
Oral squamous cell carcinomaOral squamous cell carcinoma
Oral squamous cell carcinoma
 
Leukoplakia
LeukoplakiaLeukoplakia
Leukoplakia
 
oral cancer
oral canceroral cancer
oral cancer
 
Cancer of head & neck - basics
Cancer of head & neck - basicsCancer of head & neck - basics
Cancer of head & neck - basics
 
Role of radiotherapy and chemotherapy in oral cavity cancer
Role of radiotherapy and chemotherapy in oral cavity cancerRole of radiotherapy and chemotherapy in oral cavity cancer
Role of radiotherapy and chemotherapy in oral cavity cancer
 

En vedette (10)

Chuyen de 1 qlda (sua theo nd12)
Chuyen de 1   qlda (sua theo nd12)Chuyen de 1   qlda (sua theo nd12)
Chuyen de 1 qlda (sua theo nd12)
 
Cancer of the oral cavity
Cancer of the oral cavityCancer of the oral cavity
Cancer of the oral cavity
 
Oral Cancer Exam
Oral Cancer ExamOral Cancer Exam
Oral Cancer Exam
 
Oral cancer
Oral cancerOral cancer
Oral cancer
 
Oral cancer
Oral cancerOral cancer
Oral cancer
 
Oral Cancer Stage and Grade
Oral Cancer Stage and GradeOral Cancer Stage and Grade
Oral Cancer Stage and Grade
 
Oral cancer by Dr Amol Dumbre
Oral cancer  by Dr Amol DumbreOral cancer  by Dr Amol Dumbre
Oral cancer by Dr Amol Dumbre
 
Oral cancers
Oral cancersOral cancers
Oral cancers
 
Oral Cancer
Oral CancerOral Cancer
Oral Cancer
 
Oral cancer
Oral cancerOral cancer
Oral cancer
 

Similaire à Oral cancer

Neoplasia Etiology and pathogenesis of cancer
Neoplasia Etiology and pathogenesis of cancerNeoplasia Etiology and pathogenesis of cancer
Neoplasia Etiology and pathogenesis of cancer
Subramani Parasuraman
 
Oncology ppt Zahra niegza tul Iuk ism the best ppt ever of Oncology
Oncology ppt Zahra niegza tul Iuk ism the best ppt ever of OncologyOncology ppt Zahra niegza tul Iuk ism the best ppt ever of Oncology
Oncology ppt Zahra niegza tul Iuk ism the best ppt ever of Oncology
SyedNoor53
 
Aetiology of human cancer
Aetiology of human cancerAetiology of human cancer
Aetiology of human cancer
Dr./ Ihab Samy
 

Similaire à Oral cancer (20)

EPIDEMIOLOGY OF ORAL CANCER
EPIDEMIOLOGY OF ORAL CANCEREPIDEMIOLOGY OF ORAL CANCER
EPIDEMIOLOGY OF ORAL CANCER
 
cancer2.pptx
cancer2.pptxcancer2.pptx
cancer2.pptx
 
Cancer Risk Factors
Cancer Risk FactorsCancer Risk Factors
Cancer Risk Factors
 
Epidemiology of oral cancer
Epidemiology of oral cancerEpidemiology of oral cancer
Epidemiology of oral cancer
 
1 Head and Neck. - CANCER algo epidemilogy .pdf
1 Head and  Neck. - CANCER algo epidemilogy .pdf1 Head and  Neck. - CANCER algo epidemilogy .pdf
1 Head and Neck. - CANCER algo epidemilogy .pdf
 
1. CANCER Epidemiology head and neck.pdf
1. CANCER Epidemiology head and neck.pdf1. CANCER Epidemiology head and neck.pdf
1. CANCER Epidemiology head and neck.pdf
 
Epedemiology, etiology of cancer and occupational cancers
Epedemiology, etiology of cancer and occupational cancersEpedemiology, etiology of cancer and occupational cancers
Epedemiology, etiology of cancer and occupational cancers
 
Premalignantlesions
PremalignantlesionsPremalignantlesions
Premalignantlesions
 
Head and Neck CANCER - epidemiology .pdf
Head and Neck CANCER -  epidemiology .pdfHead and Neck CANCER -  epidemiology .pdf
Head and Neck CANCER - epidemiology .pdf
 
ORAL CANCER.pptx
ORAL CANCER.pptxORAL CANCER.pptx
ORAL CANCER.pptx
 
SQUAMOUS CELL CARCINOMA - ORAL CANCER PPT
SQUAMOUS CELL CARCINOMA - ORAL CANCER PPTSQUAMOUS CELL CARCINOMA - ORAL CANCER PPT
SQUAMOUS CELL CARCINOMA - ORAL CANCER PPT
 
Neoplasia Etiology and pathogenesis of cancer
Neoplasia Etiology and pathogenesis of cancerNeoplasia Etiology and pathogenesis of cancer
Neoplasia Etiology and pathogenesis of cancer
 
Cancer & its prevention
Cancer & its preventionCancer & its prevention
Cancer & its prevention
 
Oncology ppt Zahra niegza tul Iuk ism the best ppt ever of Oncology
Oncology ppt Zahra niegza tul Iuk ism the best ppt ever of OncologyOncology ppt Zahra niegza tul Iuk ism the best ppt ever of Oncology
Oncology ppt Zahra niegza tul Iuk ism the best ppt ever of Oncology
 
cancer intro and pathogenesis
 cancer intro and pathogenesis cancer intro and pathogenesis
cancer intro and pathogenesis
 
Aetiology of human cancer
Aetiology of human cancerAetiology of human cancer
Aetiology of human cancer
 
Cancer- myths
Cancer- myths Cancer- myths
Cancer- myths
 
onclogy.pptx
onclogy.pptxonclogy.pptx
onclogy.pptx
 
Cancer Biology bbbbbnnnnbbbbjnbbbbbbbbbh
Cancer Biology bbbbbnnnnbbbbjnbbbbbbbbbhCancer Biology bbbbbnnnnbbbbjnbbbbbbbbbh
Cancer Biology bbbbbnnnnbbbbjnbbbbbbbbbh
 
Prevention and early detection of cancer ver 3.0
Prevention and early detection of cancer ver 3.0Prevention and early detection of cancer ver 3.0
Prevention and early detection of cancer ver 3.0
 

Dernier

Jigani Call Girls Service: 🍓 7737669865 🍓 High Profile Model Escorts | Bangal...
Jigani Call Girls Service: 🍓 7737669865 🍓 High Profile Model Escorts | Bangal...Jigani Call Girls Service: 🍓 7737669865 🍓 High Profile Model Escorts | Bangal...
Jigani Call Girls Service: 🍓 7737669865 🍓 High Profile Model Escorts | Bangal...
amitlee9823
 
FULL ENJOY Call Girls In Mahipalpur Delhi Contact Us 8377877756
FULL ENJOY Call Girls In Mahipalpur Delhi Contact Us 8377877756FULL ENJOY Call Girls In Mahipalpur Delhi Contact Us 8377877756
FULL ENJOY Call Girls In Mahipalpur Delhi Contact Us 8377877756
dollysharma2066
 
Verified Trusted Call Girls Adugodi💘 9352852248 Good Looking standard Profil...
Verified Trusted Call Girls Adugodi💘 9352852248  Good Looking standard Profil...Verified Trusted Call Girls Adugodi💘 9352852248  Good Looking standard Profil...
Verified Trusted Call Girls Adugodi💘 9352852248 Good Looking standard Profil...
kumaririma588
 
Peaches App development presentation deck
Peaches App development presentation deckPeaches App development presentation deck
Peaches App development presentation deck
tbatkhuu1
 
➥🔝 7737669865 🔝▻ dehradun Call-girls in Women Seeking Men 🔝dehradun🔝 Escor...
➥🔝 7737669865 🔝▻ dehradun Call-girls in Women Seeking Men  🔝dehradun🔝   Escor...➥🔝 7737669865 🔝▻ dehradun Call-girls in Women Seeking Men  🔝dehradun🔝   Escor...
➥🔝 7737669865 🔝▻ dehradun Call-girls in Women Seeking Men 🔝dehradun🔝 Escor...
amitlee9823
 
Anamika Escorts Service Darbhanga ❣️ 7014168258 ❣️ High Cost Unlimited Hard ...
Anamika Escorts Service Darbhanga ❣️ 7014168258 ❣️ High Cost Unlimited Hard  ...Anamika Escorts Service Darbhanga ❣️ 7014168258 ❣️ High Cost Unlimited Hard  ...
Anamika Escorts Service Darbhanga ❣️ 7014168258 ❣️ High Cost Unlimited Hard ...
nirzagarg
 
➥🔝 7737669865 🔝▻ Bokaro Call-girls in Women Seeking Men 🔝Bokaro🔝 Escorts S...
➥🔝 7737669865 🔝▻ Bokaro Call-girls in Women Seeking Men  🔝Bokaro🔝   Escorts S...➥🔝 7737669865 🔝▻ Bokaro Call-girls in Women Seeking Men  🔝Bokaro🔝   Escorts S...
➥🔝 7737669865 🔝▻ Bokaro Call-girls in Women Seeking Men 🔝Bokaro🔝 Escorts S...
amitlee9823
 
ab-initio-training basics and architecture
ab-initio-training basics and architectureab-initio-training basics and architecture
ab-initio-training basics and architecture
saipriyacoool
 
Whitefield Call Girls Service: 🍓 7737669865 🍓 High Profile Model Escorts | Ba...
Whitefield Call Girls Service: 🍓 7737669865 🍓 High Profile Model Escorts | Ba...Whitefield Call Girls Service: 🍓 7737669865 🍓 High Profile Model Escorts | Ba...
Whitefield Call Girls Service: 🍓 7737669865 🍓 High Profile Model Escorts | Ba...
amitlee9823
 
Escorts Service Basapura ☎ 7737669865☎ Book Your One night Stand (Bangalore)
Escorts Service Basapura ☎ 7737669865☎ Book Your One night Stand (Bangalore)Escorts Service Basapura ☎ 7737669865☎ Book Your One night Stand (Bangalore)
Escorts Service Basapura ☎ 7737669865☎ Book Your One night Stand (Bangalore)
amitlee9823
 

Dernier (20)

Jigani Call Girls Service: 🍓 7737669865 🍓 High Profile Model Escorts | Bangal...
Jigani Call Girls Service: 🍓 7737669865 🍓 High Profile Model Escorts | Bangal...Jigani Call Girls Service: 🍓 7737669865 🍓 High Profile Model Escorts | Bangal...
Jigani Call Girls Service: 🍓 7737669865 🍓 High Profile Model Escorts | Bangal...
 
Pooja 9892124323, Call girls Services and Mumbai Escort Service Near Hotel Hy...
Pooja 9892124323, Call girls Services and Mumbai Escort Service Near Hotel Hy...Pooja 9892124323, Call girls Services and Mumbai Escort Service Near Hotel Hy...
Pooja 9892124323, Call girls Services and Mumbai Escort Service Near Hotel Hy...
 
FULL ENJOY Call Girls In Mahipalpur Delhi Contact Us 8377877756
FULL ENJOY Call Girls In Mahipalpur Delhi Contact Us 8377877756FULL ENJOY Call Girls In Mahipalpur Delhi Contact Us 8377877756
FULL ENJOY Call Girls In Mahipalpur Delhi Contact Us 8377877756
 
8377087607, Door Step Call Girls In Kalkaji (Locanto) 24/7 Available
8377087607, Door Step Call Girls In Kalkaji (Locanto) 24/7 Available8377087607, Door Step Call Girls In Kalkaji (Locanto) 24/7 Available
8377087607, Door Step Call Girls In Kalkaji (Locanto) 24/7 Available
 
Sweety Planet Packaging Design Process Book.pptx
Sweety Planet Packaging Design Process Book.pptxSweety Planet Packaging Design Process Book.pptx
Sweety Planet Packaging Design Process Book.pptx
 
Verified Trusted Call Girls Adugodi💘 9352852248 Good Looking standard Profil...
Verified Trusted Call Girls Adugodi💘 9352852248  Good Looking standard Profil...Verified Trusted Call Girls Adugodi💘 9352852248  Good Looking standard Profil...
Verified Trusted Call Girls Adugodi💘 9352852248 Good Looking standard Profil...
 
call girls in Vaishali (Ghaziabad) 🔝 >༒8448380779 🔝 genuine Escort Service 🔝✔️✔️
call girls in Vaishali (Ghaziabad) 🔝 >༒8448380779 🔝 genuine Escort Service 🔝✔️✔️call girls in Vaishali (Ghaziabad) 🔝 >༒8448380779 🔝 genuine Escort Service 🔝✔️✔️
call girls in Vaishali (Ghaziabad) 🔝 >༒8448380779 🔝 genuine Escort Service 🔝✔️✔️
 
Jordan_Amanda_DMBS202404_PB1_2024-04.pdf
Jordan_Amanda_DMBS202404_PB1_2024-04.pdfJordan_Amanda_DMBS202404_PB1_2024-04.pdf
Jordan_Amanda_DMBS202404_PB1_2024-04.pdf
 
Peaches App development presentation deck
Peaches App development presentation deckPeaches App development presentation deck
Peaches App development presentation deck
 
❤Personal Whatsapp Number 8617697112 Samba Call Girls 💦✅.
❤Personal Whatsapp Number 8617697112 Samba Call Girls 💦✅.❤Personal Whatsapp Number 8617697112 Samba Call Girls 💦✅.
❤Personal Whatsapp Number 8617697112 Samba Call Girls 💦✅.
 
➥🔝 7737669865 🔝▻ dehradun Call-girls in Women Seeking Men 🔝dehradun🔝 Escor...
➥🔝 7737669865 🔝▻ dehradun Call-girls in Women Seeking Men  🔝dehradun🔝   Escor...➥🔝 7737669865 🔝▻ dehradun Call-girls in Women Seeking Men  🔝dehradun🔝   Escor...
➥🔝 7737669865 🔝▻ dehradun Call-girls in Women Seeking Men 🔝dehradun🔝 Escor...
 
Anamika Escorts Service Darbhanga ❣️ 7014168258 ❣️ High Cost Unlimited Hard ...
Anamika Escorts Service Darbhanga ❣️ 7014168258 ❣️ High Cost Unlimited Hard  ...Anamika Escorts Service Darbhanga ❣️ 7014168258 ❣️ High Cost Unlimited Hard  ...
Anamika Escorts Service Darbhanga ❣️ 7014168258 ❣️ High Cost Unlimited Hard ...
 
Pooja 9892124323, Call girls Services and Mumbai Escort Service Near Hotel Gi...
Pooja 9892124323, Call girls Services and Mumbai Escort Service Near Hotel Gi...Pooja 9892124323, Call girls Services and Mumbai Escort Service Near Hotel Gi...
Pooja 9892124323, Call girls Services and Mumbai Escort Service Near Hotel Gi...
 
➥🔝 7737669865 🔝▻ Bokaro Call-girls in Women Seeking Men 🔝Bokaro🔝 Escorts S...
➥🔝 7737669865 🔝▻ Bokaro Call-girls in Women Seeking Men  🔝Bokaro🔝   Escorts S...➥🔝 7737669865 🔝▻ Bokaro Call-girls in Women Seeking Men  🔝Bokaro🔝   Escorts S...
➥🔝 7737669865 🔝▻ Bokaro Call-girls in Women Seeking Men 🔝Bokaro🔝 Escorts S...
 
ab-initio-training basics and architecture
ab-initio-training basics and architectureab-initio-training basics and architecture
ab-initio-training basics and architecture
 
call girls in Vasundhra (Ghaziabad) 🔝 >༒8448380779 🔝 genuine Escort Service 🔝...
call girls in Vasundhra (Ghaziabad) 🔝 >༒8448380779 🔝 genuine Escort Service 🔝...call girls in Vasundhra (Ghaziabad) 🔝 >༒8448380779 🔝 genuine Escort Service 🔝...
call girls in Vasundhra (Ghaziabad) 🔝 >༒8448380779 🔝 genuine Escort Service 🔝...
 
VIP Model Call Girls Kalyani Nagar ( Pune ) Call ON 8005736733 Starting From ...
VIP Model Call Girls Kalyani Nagar ( Pune ) Call ON 8005736733 Starting From ...VIP Model Call Girls Kalyani Nagar ( Pune ) Call ON 8005736733 Starting From ...
VIP Model Call Girls Kalyani Nagar ( Pune ) Call ON 8005736733 Starting From ...
 
Whitefield Call Girls Service: 🍓 7737669865 🍓 High Profile Model Escorts | Ba...
Whitefield Call Girls Service: 🍓 7737669865 🍓 High Profile Model Escorts | Ba...Whitefield Call Girls Service: 🍓 7737669865 🍓 High Profile Model Escorts | Ba...
Whitefield Call Girls Service: 🍓 7737669865 🍓 High Profile Model Escorts | Ba...
 
Booking open Available Pune Call Girls Nanded City 6297143586 Call Hot India...
Booking open Available Pune Call Girls Nanded City  6297143586 Call Hot India...Booking open Available Pune Call Girls Nanded City  6297143586 Call Hot India...
Booking open Available Pune Call Girls Nanded City 6297143586 Call Hot India...
 
Escorts Service Basapura ☎ 7737669865☎ Book Your One night Stand (Bangalore)
Escorts Service Basapura ☎ 7737669865☎ Book Your One night Stand (Bangalore)Escorts Service Basapura ☎ 7737669865☎ Book Your One night Stand (Bangalore)
Escorts Service Basapura ☎ 7737669865☎ Book Your One night Stand (Bangalore)
 

Oral cancer