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evidence based medicine ( dr.moaweyah)
1. Evidence Based Medicine
AND
Statistical Significance
PREPARED BY :
DR.MOAWEYAH QASIM
SUPERVISED BY:
DR.HOSNI AL RAIES
PEDIATRIC ALLERGIST CONSULTANT
2.
3. What is the Evidence based
?medicine
• Evidence based medicine has been
defined by David Sackett as:
• The conscientious, explicit, and
judicious use of current best evidence
in making decisions about the care of
individual patients, to aid the delivery
of optimum clinical care to patients.
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6. ’Steps in Practicing EBM ‘5A 5
1. Ask: Asking answerable question
2. Acquire: searching for the best evidence
3. Appraise: Critically appraising the evidence
4. Apply: Applying the evidence to individual
patient care
5. Asses: Evaluating the process
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12. SYSTEMIC REVIEW
• Usually focus on a clinical topic and
answer a specific question
• The studies are reviewed, assessed,
and result summarized according to
criteria of the review question
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15. Meta-Analysis study
• When quantitative strategy for combining
the result of included studies into a single
pooled or summary estimated, it is called
a Meta-Analysis.
• Summarized a number of studies to report
the results.
• The Cochrane Collaboration has done a
lot of work of systematic reviews and
meta-analysis
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20. Randomized controlled trials
• Comparison between
intervention group (received
treatment, procedure) with
control group (no intervention).
• Follow the results and outcome
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26. Cohort study
• Cohort study are observational and not
randomized controlled studies
• Take a large number of population
• Already have same factors (treatment,
exposure, risk factors)
• Follow them for time to see the outcome
• Then compare with similar group has not
been affected by these factors
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30. Case control studies
• Patients already have specific condition
• Compared with people do not have this condition
• To look back to identify the factors or exposures
might be associated with this illness
• It is less reliable than randomized controlled and
cohort studies because statistical relationship
does not mean that the factors is are causing
the illness.
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34. Case series and reports
• Collections of reports for single case
(case report) or several cases (case
series).
• Including findings and treatment and
outcome