2. How you would store
these products?
• Vaccine
• Tetracycline
• Penicillin/Streptomycin
• Eye drops
• Vitamins
• Anthelminthics
3. Potency
100
80
60
40
20
0
1st 3r d
Improper storage of products (vaccines) leads to
Q tr Q tr
loss of potency
Potency - induces a good immune response
Once potency is lost, it cannot be regained.
4. The Cold Chain
is the system that is used to ensure that
products that need special handling are kept
within the safe temperature range of +2°C
and +8°C.
6. Three key elements
• Personnel: to manage vaccine storage and
distribution.
• Equipment: to store and transport vaccine
• Procedures: to ensure that vaccines are stored
and transported at appropriate temperatures.
7. Key Points
• Maintain efficient cold chain from point of
manufacture to vaccine use.
• All vaccines are damaged by temperatures > +8°C: a
lot of heat x short time or small amount of heat x long
period.
• Loss of potency is permanent and irreversible.
• Failure in one link of cold chain will affect product
potency. Good handling after that will not restore lost
potency.
• Repeated cold chain failure has additive effect on
product potency.
• Physical appearance of damaged vaccine may remain
unchanged.
