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The MIGHTY Greater
Saphenous Vein
Abbas A. Chamsuddn, M.D.
1-Clinical Associate Professor, Department of Radiology
AlBalamand University-School of Medicine
Beirut, Lebanon
2-Chief, IR Service, Quantum Medical Radiology
Atlanta, GA
3-Director, The Center for Laser and Interventional Surgery,
Beirut, Lebanon
Disclosure:
 Bard:
– Honoraria
– Research Grant
 Angiodynamics:
– Honoraria
 Abbott:
– Research Grant
Background
VENOUS ANATOMY:
SUPERFICIAL VEINS
• The veins of the lower extremity
that are superficial to the muscular
compartment
• Include innumerable draining
veins as well as the GSV and LSV
Lower Extremity Venous
Anatomy
 Superficial Veins
 Deep veins
 Great Saphenous Vein: Replaces “Greater”
or “Long”
 Small Saphenous Vein: Replaces “Lesser”
or “Short”
 Anterior and Posterior Accessory GSVs
 Giacomini Veins
 Truncal veins
Varicose Veins: Venous
Anatomy
 SFJ: Saphenofemoral
junction
 SPJ: Saphenopopliteal
junction
The Great Saphenous Vein
 Begins on the dorsum of
the foot
 Ascends along the medial
aspect of the leg
 Drains in the femoral vein
 Resides in a space deep to
the superficial fascia and
superficial to the deep
fascia
The Small Saphenous Vein
 Begins along the lateral aspect
of the foot
 Ascends up the midline of the
calf
 In 2/3rd of cases drains in the
popliteal vein
 In 1/3rd of cases it drains more
cephalad in the posterior thigh
 Also resides in the saphenous
space
Anterior and Posterior
Accessory GSVs
 Located in the
saphenous space
and travel parallel
anterior/porterior to
the GSV
 Anterior AGSV is
more common
Giacomini Vein
 The intersaphenous
vein
 A communication
between GSV and
SSV
Perforators
Venous Anatomy
 Deep Veins:
– Femoral and Popliteal Tibial Veins
 Superficial Veins
– Small Saphenous Vein
– Great Saphenous Vein
 Perforators: Connectors of the deep veins to the
superficial veins
 Reticular Veins: Tributaries to the saphenous
vein-connecting branch veins to deep, superficial
or perforators
 Telangiectasia: Spider Veins
Venous Anatomy
How Do Leg Veins Work?
 Blood Travels Easily
downhill!
– pumped by the
powerful action of
the heart from above
– aided by the elastic
recoil of the artery
walls
– and of course, by the
effect of gravity
How do Veins Work?
 In the standing position:
– blood has to be actively
pumped up the column of
veins
– this is achieved with our
calf muscles which
squeeze the venous
sinuses
– when the muscles relax,
the blood tends to rush
back into the leg
Venous Insufficiency
 Occur because:
1-Problem with the veins
themselves
2-Weakness of the pumping
mechanism of the calf:
 Reflux of the column of
blood through the leaky
valve
 Strain on the vein wall
 Stretching and weakness at
various points
 End result: Varicose veins!
Venous Insufficiency
 Varicose Veins:
– Dilated, protruding, tortuous saccular superficial veins.
– Develop in the superficial veins of the leg and mainly affect the long
saphenous vein
– Are higgledy-piggledy, dilated veins whose valves have failed allowing
increasing amounts of blood to reflux the wrong way down the limb
 Reticular Veins: Dilated, tortuous, non-protruding superficial veins
 Telangiectasia: Spider appearing, tortuous, non-protruding or dilated
Varicose Veins
 Symptoms:
– Often unrecognized by patients and physicians
– Aching pain
– Night cramps
– Fatigue
– Heaviness
– Restlesness
Varicose Veins
 A health issue: Left untreated:
– 50% will develop symptoms of severe venous
insufficiency:
 lower-extremity swelling
 eczema
 pigmentation
 hemorrhage
 ulceration
Venous Insufficiency
 As the vein dilates the wall
stretches in both width and
length so that the vein becomes
tortuous
 As the situation gets worse the
veins become so dilated that
large sacs form at the bends
 Turbulent flow occurs with
areas of stagnation like extreme
bends…
 …in an otherwise fast running
river and the vein can
sometimes thrombose leading
to inflammation called
superficial thrombophlebitis
Complications
 Skin discoloration
 Hemosiderin deposition
 Edema
 Lipodermatosclerosis
 Skin ulceration
 DVT
 SVT
 Thrombophlebitis
 Hemorrhage
Complications: Skin discoloration
Complications: edema,
“corona phlebectasia”
Venous Ulcers
 constitute 90% of
the ulcers seen in a
busy specialist clinic
 ulcer will never heal
unless the chain of
events which led to
it are reversed
Complications of Venous
Insufficiency
Indications for Treatment
 Absolute Indications:
– Complications from venous reflux
 Relative Indications:
– Desire to have legs without blemish
– Personal body image
– Sexual motives
Evaluation for Venous Reflux
Evaluation for Venous Reflux
Evaluation for Venous Reflux
Evaluation for Venous Reflux
Evaluation for Venous Reflux
Current Treatments
 I-Ultrasound guided sclerotherapy:
– Effective short term but no long term
durability:
 Neglen P, et al: J cardiovascular surgery 1993;
34(4): 295-301:
– Compression Slerotherapy (CST): 5 year failure rate: 51%
– Stripping: 5 years: 60% “cured”, 35% “improved”
– High ligation and CST: 5 years failure rate: 84%
Current Treatments
 II-Surgical Treatment:
– High ligation
– High ligation and stripping
Surgical Treatment
Surgical Treatment:
Stripping/SEPS
Surgical Treatment
 Dwerryhouse S et al, J Vasc Surg, April
1999; 29(4): 589-592:
– 100 pts randomized to ligation or stripping
– After 5 years, 78 pts available for duplex scan:
 29% SFJ incompetence in the stripping group
 71% SFJ incompetence in the high ligation group
Surgical Treatment
 Fisher R, et al, J Vasc Surg 2001; 34
(2):236-40
– 602 pts underwent high ligation and stripping
– 125 limbs in 77 pts available for duplex scan 34
years after ligation and stripping
– 60% limbs showed SFJ reflux by US
– Neovascularization accounted for identified
failure
Varicose Veins: Venous
Anatomy
 AL: AAGSV
 PM: PAGSV
 SEP: Superficial
External Pudendal
 SE: Superficial
Epigastric
 SCI: Superficial
circumflex iliac
“Mini” Surgical: Ambulatory
Phlebectomy
 Permits removal of nearly any incompetent
vein below the saphenofemoral and
saphenopopliteal junctions
 Major tributaries; perforators; and reticular
veins, including small reticular veins
associated with telangiectasias
 The procedure is well tolerated by patients
and produces good cosmetic results
Ambulatory Phlebectomy
Ambulatory Phlebectomy
Cyanoacrylate glue for
saphenous ablation
Nick Morrison
 Approved in Europe
 Not FDA approved
 92% GSV occlusion at
1 month
 Clot extension to SFJ
in 21%
Other Techniques:
 Coil Embolization
 Combined Coil/Foam embolization
Current Treatments
 III-Endovascular ablation of saphenous
vein:
– New treatment out of necessity:
 Trauma of surgical treatment
 High morbidity of surgical treatment
 Minimally invasive treatment
 A new “gold standard”??.....YES!
Endovascular ablation of
saphenous vein:
Radiofrequency Closure
 Received FDA clearance in 3/99
 Largest collection of published data
 Longuest F/U regarding endovenous
therapy
Radiofrequency Closure
Radiofrequency Closure
Covidien ClosureFast™
RF Closure of the GSV:
Dr Rosenblatt
 139 limbs treated in 124 patients
 Mean F/U 17.5 months (34-854 days)
 Symptomatic improvement in 97%
 Persistent and complete occlusion of the
vein in 132 limb (95%) by duplex U/S
RF Closure of the GSV:
Dr Rosenblatt
 Complications:
– 12.4%
– Transient paresthesia 11% (resolved in all by 4
months)
– Focal skin burn 1.4%
 No DVT
Endovenous Laser Therapy
 FDA Clearance:
– Diomed Jan 02
– Biolitech Jun 02
– Angiodynamics Nov 02
– Dornier Nov 02
Precision980
Diode Laser
980nm Diode Laser
Wavelength
How it works
 Water makes up over 80% of blood & Endothelial Cells
 The precision of the 980 Wavelength Targets the water to create
a “Steam Bubble”
 Resulting Heat Destroys
endothelial wall to cause
Thrombosis & Vessel
Occlusion
 Safer more precise treatment
with less chance of collateral
damage to surrounding
tissue or nerves
1470nm Diode Laser
Wavelength
Endovascular Laser
Treatment
Endovenous Laser Therapy
 Robert J. Min et al, J Vasc Interv
Radiol 2003; 14:991–996
– Large published series to date
– 499 limb in 423 patients
– Successful occlusion of GSV in 490
patients (absence of flow by duplex U/S),
98.2%
Procedure Steps:
1-Vein Puncture
Procedure Steps:
2-Placement of Vascular
Sheath
Procedure Steps:
3-Positioning of Vascular
Sheath
Procedure Steps:
4-Placement of Laser Fiber
Procedure Steps:
5-Tumescent Anesthesia
Procedure Steps:
5-Laser on, Pull Back at 3-
4mm/sec
Procedure Steps:
Final Touch
Before/After
Procedure Comparison
 Vein Stripping
– Overnight Hospital stay
– Significant Patient discomfort
– Risk of Infection and Complications of Surgical
– Long Recovery time
– Surgical Suite cost
 Laser/RFA (Minimally Invasive)
– 45min out patient procedure
– Minimal Patient Discomfort
– Minimal Complications
– 95% Efficacy
– Radiology/Office Suite Cost
Conclusion:
Beware The Power of Her
Majesty
The Mighty GSV…
Thank you for attending
PAIRS 2014
See you at PAIRS 2015,
March 12-15, Dubai UAE

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THE MIGHTY GSV2

  • 1. The MIGHTY Greater Saphenous Vein Abbas A. Chamsuddn, M.D. 1-Clinical Associate Professor, Department of Radiology AlBalamand University-School of Medicine Beirut, Lebanon 2-Chief, IR Service, Quantum Medical Radiology Atlanta, GA 3-Director, The Center for Laser and Interventional Surgery, Beirut, Lebanon
  • 2. Disclosure:  Bard: – Honoraria – Research Grant  Angiodynamics: – Honoraria  Abbott: – Research Grant
  • 4. VENOUS ANATOMY: SUPERFICIAL VEINS • The veins of the lower extremity that are superficial to the muscular compartment • Include innumerable draining veins as well as the GSV and LSV
  • 5. Lower Extremity Venous Anatomy  Superficial Veins  Deep veins  Great Saphenous Vein: Replaces “Greater” or “Long”  Small Saphenous Vein: Replaces “Lesser” or “Short”  Anterior and Posterior Accessory GSVs  Giacomini Veins  Truncal veins
  • 6. Varicose Veins: Venous Anatomy  SFJ: Saphenofemoral junction  SPJ: Saphenopopliteal junction
  • 7. The Great Saphenous Vein  Begins on the dorsum of the foot  Ascends along the medial aspect of the leg  Drains in the femoral vein  Resides in a space deep to the superficial fascia and superficial to the deep fascia
  • 8. The Small Saphenous Vein  Begins along the lateral aspect of the foot  Ascends up the midline of the calf  In 2/3rd of cases drains in the popliteal vein  In 1/3rd of cases it drains more cephalad in the posterior thigh  Also resides in the saphenous space
  • 9. Anterior and Posterior Accessory GSVs  Located in the saphenous space and travel parallel anterior/porterior to the GSV  Anterior AGSV is more common
  • 10. Giacomini Vein  The intersaphenous vein  A communication between GSV and SSV
  • 12. Venous Anatomy  Deep Veins: – Femoral and Popliteal Tibial Veins  Superficial Veins – Small Saphenous Vein – Great Saphenous Vein  Perforators: Connectors of the deep veins to the superficial veins  Reticular Veins: Tributaries to the saphenous vein-connecting branch veins to deep, superficial or perforators  Telangiectasia: Spider Veins
  • 14. How Do Leg Veins Work?  Blood Travels Easily downhill! – pumped by the powerful action of the heart from above – aided by the elastic recoil of the artery walls – and of course, by the effect of gravity
  • 15. How do Veins Work?  In the standing position: – blood has to be actively pumped up the column of veins – this is achieved with our calf muscles which squeeze the venous sinuses – when the muscles relax, the blood tends to rush back into the leg
  • 16. Venous Insufficiency  Occur because: 1-Problem with the veins themselves 2-Weakness of the pumping mechanism of the calf:  Reflux of the column of blood through the leaky valve  Strain on the vein wall  Stretching and weakness at various points  End result: Varicose veins!
  • 17. Venous Insufficiency  Varicose Veins: – Dilated, protruding, tortuous saccular superficial veins. – Develop in the superficial veins of the leg and mainly affect the long saphenous vein – Are higgledy-piggledy, dilated veins whose valves have failed allowing increasing amounts of blood to reflux the wrong way down the limb  Reticular Veins: Dilated, tortuous, non-protruding superficial veins  Telangiectasia: Spider appearing, tortuous, non-protruding or dilated
  • 18. Varicose Veins  Symptoms: – Often unrecognized by patients and physicians – Aching pain – Night cramps – Fatigue – Heaviness – Restlesness
  • 19. Varicose Veins  A health issue: Left untreated: – 50% will develop symptoms of severe venous insufficiency:  lower-extremity swelling  eczema  pigmentation  hemorrhage  ulceration
  • 20. Venous Insufficiency  As the vein dilates the wall stretches in both width and length so that the vein becomes tortuous  As the situation gets worse the veins become so dilated that large sacs form at the bends  Turbulent flow occurs with areas of stagnation like extreme bends…  …in an otherwise fast running river and the vein can sometimes thrombose leading to inflammation called superficial thrombophlebitis
  • 21. Complications  Skin discoloration  Hemosiderin deposition  Edema  Lipodermatosclerosis  Skin ulceration  DVT  SVT  Thrombophlebitis  Hemorrhage
  • 24. Venous Ulcers  constitute 90% of the ulcers seen in a busy specialist clinic  ulcer will never heal unless the chain of events which led to it are reversed
  • 26. Indications for Treatment  Absolute Indications: – Complications from venous reflux  Relative Indications: – Desire to have legs without blemish – Personal body image – Sexual motives
  • 32. Current Treatments  I-Ultrasound guided sclerotherapy: – Effective short term but no long term durability:  Neglen P, et al: J cardiovascular surgery 1993; 34(4): 295-301: – Compression Slerotherapy (CST): 5 year failure rate: 51% – Stripping: 5 years: 60% “cured”, 35% “improved” – High ligation and CST: 5 years failure rate: 84%
  • 33. Current Treatments  II-Surgical Treatment: – High ligation – High ligation and stripping
  • 36. Surgical Treatment  Dwerryhouse S et al, J Vasc Surg, April 1999; 29(4): 589-592: – 100 pts randomized to ligation or stripping – After 5 years, 78 pts available for duplex scan:  29% SFJ incompetence in the stripping group  71% SFJ incompetence in the high ligation group
  • 37. Surgical Treatment  Fisher R, et al, J Vasc Surg 2001; 34 (2):236-40 – 602 pts underwent high ligation and stripping – 125 limbs in 77 pts available for duplex scan 34 years after ligation and stripping – 60% limbs showed SFJ reflux by US – Neovascularization accounted for identified failure
  • 38. Varicose Veins: Venous Anatomy  AL: AAGSV  PM: PAGSV  SEP: Superficial External Pudendal  SE: Superficial Epigastric  SCI: Superficial circumflex iliac
  • 39. “Mini” Surgical: Ambulatory Phlebectomy  Permits removal of nearly any incompetent vein below the saphenofemoral and saphenopopliteal junctions  Major tributaries; perforators; and reticular veins, including small reticular veins associated with telangiectasias  The procedure is well tolerated by patients and produces good cosmetic results
  • 42. Cyanoacrylate glue for saphenous ablation Nick Morrison  Approved in Europe  Not FDA approved  92% GSV occlusion at 1 month  Clot extension to SFJ in 21%
  • 43. Other Techniques:  Coil Embolization  Combined Coil/Foam embolization
  • 44. Current Treatments  III-Endovascular ablation of saphenous vein: – New treatment out of necessity:  Trauma of surgical treatment  High morbidity of surgical treatment  Minimally invasive treatment  A new “gold standard”??.....YES!
  • 46. Radiofrequency Closure  Received FDA clearance in 3/99  Largest collection of published data  Longuest F/U regarding endovenous therapy
  • 50. RF Closure of the GSV: Dr Rosenblatt  139 limbs treated in 124 patients  Mean F/U 17.5 months (34-854 days)  Symptomatic improvement in 97%  Persistent and complete occlusion of the vein in 132 limb (95%) by duplex U/S
  • 51. RF Closure of the GSV: Dr Rosenblatt  Complications: – 12.4% – Transient paresthesia 11% (resolved in all by 4 months) – Focal skin burn 1.4%  No DVT
  • 52. Endovenous Laser Therapy  FDA Clearance: – Diomed Jan 02 – Biolitech Jun 02 – Angiodynamics Nov 02 – Dornier Nov 02
  • 54. 980nm Diode Laser Wavelength How it works  Water makes up over 80% of blood & Endothelial Cells  The precision of the 980 Wavelength Targets the water to create a “Steam Bubble”  Resulting Heat Destroys endothelial wall to cause Thrombosis & Vessel Occlusion  Safer more precise treatment with less chance of collateral damage to surrounding tissue or nerves
  • 57. Endovenous Laser Therapy  Robert J. Min et al, J Vasc Interv Radiol 2003; 14:991–996 – Large published series to date – 499 limb in 423 patients – Successful occlusion of GSV in 490 patients (absence of flow by duplex U/S), 98.2%
  • 63. Procedure Steps: 5-Laser on, Pull Back at 3- 4mm/sec
  • 66. Procedure Comparison  Vein Stripping – Overnight Hospital stay – Significant Patient discomfort – Risk of Infection and Complications of Surgical – Long Recovery time – Surgical Suite cost  Laser/RFA (Minimally Invasive) – 45min out patient procedure – Minimal Patient Discomfort – Minimal Complications – 95% Efficacy – Radiology/Office Suite Cost
  • 67. Conclusion: Beware The Power of Her Majesty The Mighty GSV…
  • 68. Thank you for attending PAIRS 2014 See you at PAIRS 2015, March 12-15, Dubai UAE