The continual evolution of compound management labs in terms of sample capacity and capabilities provides opportunities to improve the associated QA and QC operations. As new technologies enable support of greater plate densities and library sizes, new approaches to QA and QC must follow suit.
• Review of potential for error in compound management labs and impact of new technology on QA/QC efficiency
• Leveraging sample color to quickly identify problems
• Novel methods for monitoring the health of large sample libraries over time
• Correlating visual properties of solubilized samples to experimental results and calculated properties
Accumulation of error causes failure:Liquid handler slightly off + plate slightly off = errorWells are 10% off spec (2.25mm distance center to center = 40 pixels, wells are off by 4 pixels in both cases)