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بسم ال الرحمن الرحيم
INTERSEX 
By 
Mohamed El-Sawy 
Prof. in Pediatric Department 
Faculty of Medicine- Ain Shams University
Undifferntiated Gonad 
Wolffian duct system 
Mullerian duct system
GONADAL DEVELOPMENT 
INTERNAL GENITALIA 
7-8 
weeks
External Genitalia 
Normal Abnormal 
Intersex 
Hypogenitalism
Intersex 
True 
Pseudo: Female 
Male
True Hermaphroditism 
Definition • 
Types • 
Chromosomal Pattern •
DDeeffeecctt ooff TTeessttiiccuullaarr DDiiffffeerreennttiiaattiioonn 
Absent HY antigen 
Target Tissue Resistance 
Embryonic Testicular Regression Syndrome 
Bilateral Anorchia
DDyysshhoorrmmoonnooggeenneessiiss
UUtteerriinnee HHeerrnniiaa SSyynnddrroommee
DDeeffeecctt ooff AAnnddrrooggeenn AAccttiioonn 
Testicular Feminization 
Alpha-Reductase Deficiency-5
..PPaarrttiiaall TT..FF
..PPaarrttiiaall TT..FF
..PPaarrttiiaall TT..FF
αα RReedduuccttaassee DDeeffiicciieennccyy--55
αα RReedduuccttaassee DDeeffiicciieennccyy--55
DDSSDD TTEEAAMM 
Multidisciplinary 
Endocrine 
Genetics 
Urology 
Psychology/Psychiatry 
Religious counseling 
Gynecologist
SSEEXX AASSSSIIGGNNMMEENNTT 
Actual Anatomy 
Available surgical intervention 
Functionl Endocrinology 
Chromosomal Pattern 
Non functioning female better than non 
functioning male
Prader Willi Syndrome
PPuurree XXXX GGoonnaaddaall DDyyssggeenneessiiss
Thank You

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