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CPAPs for Premature Infants
Report on:
Continuous Positive Airway Pressure (CPAPs)
For Premature infants
Submitted By:
Raheel Sayeed
Id# 16355047
Submitted To:
Prof.Paul Junor
Dated:July05,2012
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Table Of Contents
1.1.Introduction 4
1.2.Aim of the project 4
2.1.Basic Physiology of respiratory system 6-8
3.1.Artificial ventilators 10-12
4.1.Effect Of CPAP 12-14
5.1.Types of CPAP 14-15
6.1.Methods and Material 15-21
7.1.1. Procedure 21-22
8.1.1.Other Ideas 23
8.1.Discussion 24
Conclusion 24
References
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Acknowledgement
Success of any project largely depends on the peoples associated with it. Their
support, guidance and their encouragement bring up confidence in you. In
this regard I really appreciate and thankful to all my colleagues and teachers
who made me self confident and motivated for this project. My special thanks
to Prof. Paul Junor who gives me tremendous support and help throughout
this project .Without his support and guidelines I am never be able to
withstand and take this opportunity to express my ideas in accordance with
the project. The assistance and hold up acknowledged from all the members
who have a say to this project, was imperative for the accomplishment of the
project. I am indebted for their continuous support and help.
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1.1.Introduction
CPAPs (continuous positive air way pressure) is a mechanical mean to deliver air pressure to
those patients who feels problem in normal breathing. It is a noninvasive technique which has
been use for the decades of years. This technique of providing artificial breathing gives them an
ease to support in their daily life. It may also enhance their life to be living healthy. An
effective ,cheap and easy way to maintain a normal healthy life. This is not the limit, beyond it,
this technique may also be involved in life saving activity for the premature infants as their
immature lungs, sometime, are not capable to breath their own due to their weak intercostals
muscles. for a while, this technique is use to increase the oxygen level in their blood by given
them oxygen support with the same principle with a different source.[6]
So the CPAPs becomes
the multi diverse technique which not only helpful in adults but in preterm infants as well. It also
have some vital role in therapy of disorders like sleep apnea, respiratory distress
syndrome(RDS),dypnea and many more others.[3,4]
Since the gestation period the struggle for survival starts. It is the natures’ tendency to support
the one who struggles so as the theory of Darwin says “Survival of the fittest”. As soon the baby
is out of mother’s womb it starts it new journey of life. Many are lucky to be out by the normal
growth period but some aren’t; they face certain complications like chronic lung disease,
developmental delay, hearing impairment, intraventricular haemorrhage and respiratory distress
syndrome. These are some of the complication which is very high in neonates. As premature
have a smaller lungs their ability of breathing rate is much higher than adults. They need a
constant supply of air pressure depending on their gestation week / weight. To achieve this
constant air supply which can improve the mortality rate of the premature we can use
Ventilators, Continuous Positive Air Pressure’s and Bubble Continuous Positive Air Pressure’s.
[1, 2]
1.2.Aim of the project
Basically this project is design to minimize the complexity and the cost of the CPAPs so that it
can be easily used in the developing countries like Ghana a state of Africa where the mortality
rate is on increasing in preterm infants mostly because of respiratory problems and immature
lungs. So there is a need of cheap machines which can easily be affordable and even can
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eliminate the cost of hospital expenses, power consumptions and its mode of operation is as
simple as on one touch it can be operated. Considering all these options, we in Latrobe
University trying to make such type of device which can be simple in use and should be easy in
operation. The machine should be powered by any natural resource or a source which doesn’t
require any consumable expenses. In this regard we are trying to make a respiratory control
assit device called CPAPs (continuous positive airway pressure) which will work on Solar
Power energy or any other renewable resource which can creates its own energy by applying
any technology.
1.2.1.Why use CPAPs
Continuous positive airway pressure (CPAPs) has been used in patients which have some
particular respiratory problems, this included sleep apnea in which there is some disorders in
breathing during sleeping which includes pause in breath for some seconds[28]
, sleep disorders
associated with heart failure, restrictive pulmonary diseases (decrease in total pulmonary
capacity)[29]
, severe stable chronic obstructive pulmonary disease, and the obesity-
hypoventilation syndrome in which overweight people cannot breath well and this will cause
decrease in oxygen concentration in blood with an increase of CO2 concentration[30]
.In this
regard, CPAPs has given dramatic change in significant physiological reimbursement, by
improving the worth of life, and even longer survival in some of the cases. CPAPs with a nasal
mask is therefore broad way to balance the increase folding of the air way.[7]
CPAPs giving a constant positive air pressure to the patient during natural breathing by
decreasing the work of breathing (WOB). It is use in cure of cardiovascular problems by treating
in various obstructive disease of sleeping disorders. It also can be use for associated pulmonary
disorders with congestive heart failures. Role of CPAPs in case of sleep apnea is really effective
and even in case of premature infants is an undeniable fact. Because the lungs of preterm babies
are very delicate and even it is quite different in shape as compare to an adult person.
2.1.Basic Physiology of respiratory system
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Lungs are the main respiratory organ of the respiratory system where all the main function of
respiration has to be done. From exchange of gases to diffusion of gases into and from the blood,
all process is taking place in this organ. Two main phenomenons which involve in the respiration
process are;
• Inspiration
• Expiration
In the process of inspiration ,atmospheric air is taking in through the nasal cavity from where it
will enters into the pharynx. The pharynx has two openings or it has the common opening for
food and air. The pharynx open into the larynx and esophagus, the air will enter into the larynx
because the esophagus is the path of food. The larynx then enters into a long tube like structure
called the trachea. The trachea and bronchi further divided into two bronchioles each of which
enters in the two sets of lungs. This whole process is an active phenomenon while in case of
expiration which is a passive procedure during a quiet breathing; the air which was taken in will
be exhale out and gives the gas in return called CO2.
Actually, the lungs are elastic in nature which can expand and contract during the entire process
of respiration and the muscle involved in this mechanism are abdominal muscles called rectus
abdominis, the intercostals muscles and the diaphragm. The rectus abdominal muscle provide
support in a force breathing, mostly after a physical exercise or after doing some hard work.
As lungs inflate and deflate the ribcage and abdomen increase and decreases. As volume and
pressure are related, altering the lung volume changes the air pressure in lungs.
• Increasing lung volume lowers air pressure(pushes ribcages & abdomen Outwards)
• Decreasing lung volume higher air pressure(pulling ribcages & abdomen Inwards)
Air flows from the region of higher concentration to the region of lower concentration, so air
flows into lungs when pressure decreases below atmospheric level and out when pressure
increases above atmospheric level. During Inhalation contraction of external intercostals muscle
and diaphragm occurs and during Exhalation contraction of internal intercostals muscle occurs.
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Fig:1
Source: http://www.google.com.au/imgres?q=physiology+of+respiratory
Considering the premature babies the lung and chest wall develop till 2-8 years of age. Below are
the comparisons of the adult as well as healthy infant’s facts of lung state.
1. Alveolisation continues beyond infant age.
• 20-50 million alveoli at birth in a healthy infant.
• 300 million by age 8 years.
2. Increase in alveoli tends to increase in alveoli surface area.
• 2.8 m2
at birth.
• 32m2
at 8 years of age.
• 75m2
at adulthood.
3. Ventilation through the pores of Kohn & Lambert Canal is not well developed in early
years.
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4. Lung matrix of the neonate contain small amount of collagen (elastin to collagen ratio
changes during the 1st
month & years of life which affects lung stiffness as well as
potential for over distension & recoil.
5. Lung recoil (elastin) increases with age in children over 6 years of age.
6. Elastin recoil of an infant’s chest wall is close to zero & with age increases, because of
progressive ossification of the ribcage & intercostal muscle tone.
7. Orientation of ribs is horizontal in infants & later by 10 years of age, the arrangement is
downward.
8. Tongue is disproportionately large related to mouth.
9. Larynx is higher in neck(above Cervical4) [5,6]
2.1.2. Mechanism of Breathing
The mechanism of breathing involves the process of diffusion. The phenomenons of diffusion
define as; the movement of molecules from a region of higher concentration to a region of lower
concentration and this is actually happening in case of breathing mechanism. The O2 is diffuses
into the blood when we breath in because the concentration of O2 is lower in the blood as in
alveoli so it will diffuse in the blood and the blood becomes oxygenated while the concentration
of CO2 is higher at the same time in blood then in alveoli so it will diffuse in alveoli. This whole
process is done by the breathing mechanism as we continuously taking in the fresh oxygen and
passively given out the carbon dioxide.
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Fig: 2
Source: http://www.google.com.au/imgres
In natural breathing, a pressure gradient is generated due to which the process of breathing
occurred. Figure 2 demonstrating a diagrammatic view of the breathing mechanism that when we
take air in, the volume of the lungs becomes increases which corresponds to the decrease of
pressure in thoracic cavity which in results contracts the diaphragm outwards and also the chest
becomes expended as demonstrated in Fig:2.Now due to low pressure inside the thoracic cavity
and high atmospheric pressure the passive phenomenon of expiration would be occur to maintain
the equilibrium condition and the diaphragm and chest would again be relax and the intra
thoracic pressure again increases and this cycle continues throughout the life.
2.1.3. Motor pathways
The diaphragm is the major muscle in the process of respiration which is creating the negative
pressure due to which, the process of inspiration would be taken place. It is a thin sheet of
muscle which will separate the thorax from the abdomen. Other muscles which are involve in the
respiration process are the internal and external intercostals muscles.[27]
3.1. Artificial ventilators:
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It consists of a mask, an oxygen source and an air bag. There is a valve to separates inhalation
and exhalation process. Air bag work as a manual pump for the continuous supply of oxygen. It
is use for the temporary purposes.
3.1.2. Ventilators:
They are usually design to work as human lungs or as an alternative of lung in case of
pulmonary disorders. Ventilators have different modes which can be run-in accordance with type
of disorder or according to the patient needs.
Two basic ventilations are:
Negative Pressure Ventilation: inspiration occurs because of negative pressure creates in
pleural cavity because there is low concentration of air inside the pleural cavity and high
concentration in the atmosphere. So –ve pressure ventilators are required.
Positive Pressure Ventilation: when the concentration is much higher inside the pleural cavity,
it will generate positive pressure in the pleural cavity so patient needs to expire.
Positive pressure ventilators are used in wide range of disorders. It is frequently use in
spontaneous mode where the patient required less effort to respire. While in case of compulsory
breaths, ventilators controlling all the parameters like tidal volume, respiration rates, etc.These
kind of breath are given to that patient who are unable to respire by their own efforts.
3.1.3.Types of Ventilator:
Two types of ventilator are:
Anesthetic Ventilator: It refers to use during operation or surgery when the patient is in
unconscious state.
Intensive Care Ventilator: In this air is delivering to the patient for inhalation. This type will
give the precise control for the respiration process.
Terminologies Used In ventilation:
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Fig:3
Source: http://www.google.com.breathing+mechanics+inspiration+and+expiration
3.1.4.Lung Compliance:
It is actually the ability of lungs and alveoli to expand on delivering a certain or required amount
of gas. It is usually in liter/cmH2O.It also refers to change in volume of the gas inside the lungs.
3.1.5.Airway Resistance:
It is resistance in flow of air during the entire process of respiration which will get increase in
bronchioles because of its smaller diameter.
3.1.6.Mean Airway Pressure:
It is basically the pressure of the air between aspiratory and expiratory phase.
Aspiratory Pause Time: This phase will occur when the alveolar pressure becomes equal to the
patient circuit. On that phase there is no flow of gas is taking place, so there is a time interval or
a pause state which is called as pause time.
3.1.7.Tidal Volume: It is the total time inspired and expired during each breathing cycle. It can
be calculated by getting the product of flow rate and inhalation time.
Respiratory rate: Number of breath per second.
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Assist control mode and SIMV mode: In these modes ventilator actually measures the breath
by taking an average of previous four breaths.
CMV: conventional mechanical ventilation is providing a forced ventilation to achieve normal
breathing. It determines the tidal volume at a respiratory frequency.
IMV: Time delay between each breath.
4.1.Effect of CPAP:
The CPAPs has been used to overcome the problems related with respiration process. It helps in
maintaining the oxygenation in blood and playing a vital role in decreasing the airway resistance
during the process of breathing mostly in premature infants. It also helps in increasing functional
residual capacity and has the tremendous effect on the immature lungs of preterm babies. CPAPs
maintain the air pressure in the lungs by giving a constant amount of pressure in accordance with
the required pressure. This is the beauty of this device that it has been designed as for the patient
needs. CPAPs therapy helps in maintaining the transpulmonary function of lungs by increasing
the functional residual capacity and thus by decreasing the bulk requirement of oxygen. It also
• recover lung compliance
• decrease airway resistance
• lessen the work of breathing
• enhance the ventilation-perfusion percentage.
4.1.2.Effect on Cardiovascular Stability:
High pressure of CPAPs can have a harmful effect on the cardiovascular system. The continuous
or high pressure of CPAPs results in compressing the heart vessels of right sides which in return,
will result in the decreased cardiac output due to which the amount of oxygen which is needed
by the tissues of different organs is not sufficiently supplied. The major problem is with the
decrease cardiac output which will then subjected towards acidosis and causing the problem with
low blood pressure[14]
.In this case , the practice with the low pressure of CPAPs is highly
recommendable[15]
.However, sometime even the lower pressure becomes the cause for distress in
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respiration and can cause some severe adverse effects. So it is quite necessary for the operator to
having a good familiarity with the level and standard pressure of CPAPs. In case of preterm
infants, one should have to be well known with limitations of their immature lungs otherwise it
may lead towards some severe degree of illness [14,17]
.
4.1.3.Effect of CPAP in Pulmonary Function:
Heart is the main pumping organ of the body through which the blood pumps throughout the
body. The heart will serves as a motor which plays an important role to maintain homeostasis of
the blood flow. When this pumping organ becomes unable to pump blood due to any disorder,
this will cause heart failure or congestive heart failure (CHF). Contrary of advancement in
medical sciences, this problem will remain the major cause of increasing mortality rate related
with the failure of heart. One of the major effect of CHF is because of lungs dysfunction in
which the fluidic concentration (lung edema) becomes increases which in turn will give rise to
muscles fatigue in performing routine exercises.[21]
One of the way to reduce or to control the pulmonary edema is by giving the relatives drugs or
by supplying forced Oxygen to patient in order to improve the performance of myocardial
muscles followed by the oxygenation. But sometime the crucial respiratory failure would be
occur and the only chance for survival will be the mechanical ventilation. The other way to get
avoided with these kind of disease in a very initial stage is by providing the CONTINOUS
POSITIVE AIRWAY PRESSURE which has been used from a long time to those
patients[13,17].
.By applying a constant positive air pressure will help to sustain oxygen
concentration in the blood and helps to improves the lungs edema and the pulmonary function.
This will also cause to decrease in respiratory work and work of breathing by decreasing in left
ventricle preload and after load.[23,24]
So the CPAPs may also be beneficial in use to increase the physical exercise capacity of the
patients having congestive heart failures. Constant use of CPAP for two weeks enhances the
stability of the pulmonary function with an increase stability of the regular exercise. CPAPs
therapy is helpful in maintaining the cardiac output in consideration with the treatment of CHF
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patients it shows a favorable result which implies that CPAP may not only use for the cure of
disease with heart and lung but it may also increase the tolerance associated with the physical
exercise.
In a nutshell, it is quite clear that CPAP therapy not only enhances the cardiopulmonary
functions but it is equally helpful in increasing the capability of regular exercise.[23]
4.1.4.Effect On Central Nervous System
CPAPs therapy as in relation with their effects on nervous system reveals some adverse effects.
It may increase the intracranial pressure which may results to decrease in arterial pressure or the
blood pressure and this will cause to reduce the cerebral perfusion pressure. Intracranial pressure
is actually the pressure gradient of the brain tissues. In a supine position this pressure is 7 to 10
mmHg while in vertical position it becomes -10mmHg.As in case of CPAPs therapy the
intracranial pressure shows some variation with the type of CPAPs delivered i.e. in HeadBox
type it is showing a higher pressure rather in nasal prong or endotracheal one. It has been proved
that the high pressure of CPAPs influence the central venous pressure by increasing it and this
will cause an increase concentration of CO2 with a decrease level of O2 in blood, particularly
when it comes near to 8cmH2O.[31]
5.1.Types of CPAP :
5.1.2.Critical care ventilators.
This type of CPAPs have a high capacity to produce air flow as required by the patient. It may
really helpful for the cure of acute respiratory distress as compare to the portable CPAPs but the
problem with this type is its large size and complications in operation because even its
monitoring console is quite complicated as the basic aim of CPAPs is its ease of use, particularly
in the noninvasive techniques. Moreover, the device is quite expensive as compare to portable
one and heavy in weight which may interfere in handling.[32]
5.1.3.Boussignac CPAP system
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This type of CPAPs system consists of a valve which controls the pressure of air flow. It is
comprises of a plastic tube on-face mask valve which controls the air pressure, ranging from
2.5cmH2O to 10cmH2O.The valve itself control the flow without using any flow generator. The
valve consist of a plastic tube with a length of 5.5cm and the internal diameter is about
1.3cm.This valve is attached to a face mask which then attach to the patients nasal cavity and
mouth. The basic principle of this device works on the low pressure and high speed of oxygen
molecules which then transformed into the high pressure flow and thus maintain the required
pressure to be given. The device is user friendly and easy to use in operation, so it can be taken
in an emergency procedure.[32]
6.1.Methods and Material
The basic designing of this project is based on the following;
6.2.Power Source:
The power source is the basic part of this project because we have to use the source other then
the electrical; this means that whatever be the source it must have to be generating the power
itself. It must not be the conventional which usually powered our homes. In this regard we were
trying to use “Solar Power” in order to drive the rest of the circuit or may be some other
mechanical or chemical energy of source.
6.2.1.Solar Power:
Solar energy are the rays of sunlight which can be use to produce electrical energy by means of a
device called the solar cell. This form of energy can be converted into electrical form by using
photoelectric effect or photovoltaic effect. We can also concentrate this solar energy by using
convex lenses so the resulted beam of solar energy is denser and thus generate more power.
The two ways to create electric current and voltage is;
• Photovoltaic effect
• Photoelectric effect
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Sometime these two different processes will be considered as same but there is a slight
difference in their generation of voltage. In Photovoltaic effect, using a semiconductor material
which when placed in sunlight will direct emit the voltages. On the other hand, in photoelectric
effect, transfer of electrons would be occur from the valence band to the conduction band and
due to this change in energy level from higher to lower it will emits electron and thus the
generation of voltage between two electrodes will be occur.
Fig:4
Source:http://photovoltaics.sandia.gov/docs/PVFEffIntroduction.htm
6.2.2.How to build a solar module:
Actually we can have directly purchase a solar module according to our required output. But we
can also make a solar module by having assemblies of solar cells which are grouped together in
series can make a solar module. This array or solar module can convert the sunlight energy into
the electrical energy, as one solar cell can generate approx 0.5 mV of voltage so we can organize
it as our required output which is about 12V.
6.3.DC Motor:
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Fig:5
Source: http://gilbertojunqueira.com/quick-motor-tip-of-the-day#more-51
A 12V DC motor with a wing will produce air which will then be passed to the pressure sensor
through a small pipe commonly called as Neonates Cannula. The rotating speed of the motor is
directly proportional to the voltage supplied. So we can also control the pressure of the air by
controlling the rotational speed of the motor.[10]
6.4.1.Pressure Sensor
This is the most important part of the project or the key area for the required output. Pressure
sensor detects the current pressure of the air that is supplied from the fan through this we can
control the pressure according to a preset value or can be programmed in either way. After the
pressure is regulated, air is supplied to the tubing from which it will flow to the patient nostrils
through nasal cannula or a breathing mask.
6.4.2.MPX2010 Pressure Sensor(COMPENSATED PRESSURE SENSOR)
In this regard we find the MPX2010 pressure sensor is the most appropriate and its output
voltage is directly proportional to the applied pressure. This pressure sensor will convert the air
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pressure into the voltage and we can easily manage the required air pressure by checking the
output volts.[11]
Characteristics and features
• 0 to 10 kPa (0 to 1.45 psi)
• FULL SCALE SPAN: 25 mV
• Temperature Compensated over 0°C to + 85°C
• Unique Silicon Shear Stress Strain Gauge
• Ratiometric to Supply Voltage
• Differential and Gauge Options
Fig:6
Source: http://www.google.com.au/imgres?q=MPX2010
Application Examples
• In Respiratory Diagnostics
• Air Movement Control
• Controllers
• Pressure Switching
Pin Configuration:
1 2 3 4
Ground +Vout Vs -Vout
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Where Pin 1 is a notched pin.
Voltage Output V/s Applied Differential Pressure
The output voltage is increase with an increase in pressure side P1 in relation with pressure side
P2.likewise by raising the vacuum side P2 the voltage is also increases.
The other characteristics of the device is mentioned in the data sheet which is not necessary to
include in the report.[11]
6.5.1.Pressure ranges according to their Use:
Low Pressure
2-3 cmH2O
• Maintenance of lung Volume in very low birth weight infants
• During weaning
Medium Pressure
4-7 cmH2O
• Increasing lung volume in surfactant deficiency
• Stabilizing areas of Atelectasis
• Stabilizing obstructive airway
High pressure
8-10 cmH2O
• Preventing lungs Collapse with poor lung volume
• Improving distribution of ventilation
Ultra High
11-14 cmH2O
• Tracheal or bronchial collapse
• In severe obstruction
• Reestablishing lung volume during ECHO
Table:1
So there are specific pressure ranges of air for the specified problems in the infants according to
their difficulty need. These pressure are given to the patient according to the circumstances or in
accordance with the degree of severances of disease.[12]
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6.6.Flow Sensor:
Flow sensor serves as an emergency signal to alert for a problem condition in air pressure. It
monitors the air flow that is supplied to the patient, and outputs an emergency signal if the air
pressure is not in the desired range. This terminal can be a enhancement for the project if we get
the desired output.
Fig:7 Schematic circuit of flow detector
Source: http://www.google.com.au/imgres?q=air+flow+detector+circuit+diagram
The Figure 7 shows the circuit of air flow detector. This circuit can give a visual indication of the
rate of air flow. It can be also used to check whether there is air flow in a given space.
According to the circuit in figure 7, we can use a filament of the bulb which can sense the air
flow. When air is flowing through the filament the resistance will go on increasing because the
passing air creates heat resistance, and when the flow of air will be stop the resistance across the
resistor will be drop down because the air flowing will also removes the heat from the filament
and this variation of drop voltage can be detected by the opam (LM339) and we can generate
alarm or LED blinking as a signal in failure of air flow.
6.7.1.Nasal Prongs
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This device is consisting of plastic tube which will attach to the patient. It consist of two small
tube called the prongs which will place in the patients nostrils as shown in the figure 8.The other
tubular shape structured is connected to the air supply. Air flows from these prongs and the nasal
cannula is connected to the supplied air by the dc motor. The nasal cannula carries 1–5 liters of
air per minute or as desired.
The nasal prongs are a device used to deliver supplemental airflow to the person in need of
respiratory help. This device consists of a plastic tube which fits behind the ears, and a set of two
prongs which are placed in the nostrils.
Fig:8
Source: http://www.google.com.au/imgres?q=nasal+prongs
The figure 8 show the typical Nasal Prong which is used in CPAP system. But some time it is not
user friendly and some other kind of prongs are also be used.
6.8.Tubing:
The tubing used to deliver air is about 10mm in diameter with a very low resistance in flow of
air. This tubing is about 5 to 6 meter in length or depends on the circuit requirement.
7.1.1Procedure
Power will be given to the DC motor in order to create air flow which will then be passed to
nasal prong via tubing. There is a pressure sensor which control will monitor the pressure of the
air. This pressure sensor shows the pressure of the air flow in volts and through this sensors
output we will control the air flow by controlling the speed of the motor. Now this air is passing
through the tubing supply to the patients nostrils via nasal prongs. A beaker with water with a
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graduated glass tube is connected to the expiratory tube ,which comes from the patient nostrils
.The function of this expiratory tube is to control the air pressure. The graduation is marked in
cmH2O.T his metal tube allows gas to exhaust into the water, and pressure will assorted by
adjusting the depth of the tube in water.
The Flow sensor circuit is continuously monitoring the air flow to the patient and in case of
failure of air flow it gives an alarm to check out the problem.
8.1.1.Cost Evaluation
The total cost which is given by the university is about 400$.i.e 200$ for each student. The
approximate cost for this project if it is undertaken in the present circumstances is given below.
Component Price in AUD$
DC Motor ~16.00$
Solar Pannel ~40.00$
Rechargeable Battery ~ 25.00$
Tubing Giving by the hospital
Nasal Prongs Giving by the hospital
Flow Sensor ~34.00$
Air Detector Circuit ~12.00$
Other cost ~30.00$
Table:2
8.1.2Other Ideas:
During this project I have went through some other interesting ideas which can make this project
simpler and easier in use but most of them are quite unprofessional and may kill the idea of
cheap cost. So I don’t discuss about those ideas. But one idea that clicks to my mind and is quite
good in my perspective is;
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• A simple way to charge the battery is by using a small dynamo, turned by the DC Fan
motor through a belt.
Fig:9
Source: http://www.google.com.au/imgres?q=Dc+motor+use+to+charge+the+12v+battery
The Figure 9 depicts one of my idea to generate the voltages through the same DC motor which
we will use to generate the air flow for the patient. In this, we can use two sets of DC motor and
by using a belt we can attach the axle of both the motors with each other. The one which will
take the power from the battery will generate the air flow and through this the axle of the other
motor will also be rotate creating the voltage on its input. Now this voltage can be use to charge
the same battery which is giving power to the first motor.
8.1.3.Discusssion:
The CPAP system which we want to design and implemented is a feasible project to design. But
it may take some more time and enhancements in its features and cost. Approximately the
research work has been done to implement the idea. In the report all the physiological and
technical parameter has been discussed. It is better to implement the idea in consideration with
the basic aim of this project which is the cost effectiveness and the simplicity. Because as we
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know this is not a new invention but the same invention and basic principle with some new
advancement so that it can be use to lower down the mortality rate of premature infants in some
developing countries. One other aspect of this project is that it must be user friendly and the
operation of the system must be simple so that it can easily operated even at home without any
hesitation.
Conclusion
In a nutshell, the idea is ready to implement with some more advancement. The hardware is not
completed yet. This project is quite useful as it is power saving and regardless of expenses. The
natural resources are use to power the module and can easily be use in developing countries.
24 | P a g e

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Final Report_05july_2012docs

  • 1. CPAPs for Premature Infants Report on: Continuous Positive Airway Pressure (CPAPs) For Premature infants Submitted By: Raheel Sayeed Id# 16355047 Submitted To: Prof.Paul Junor Dated:July05,2012 1 | P a g e
  • 2. CPAPs for Premature Infants Table Of Contents 1.1.Introduction 4 1.2.Aim of the project 4 2.1.Basic Physiology of respiratory system 6-8 3.1.Artificial ventilators 10-12 4.1.Effect Of CPAP 12-14 5.1.Types of CPAP 14-15 6.1.Methods and Material 15-21 7.1.1. Procedure 21-22 8.1.1.Other Ideas 23 8.1.Discussion 24 Conclusion 24 References 2 | P a g e
  • 3. CPAPs for Premature Infants Acknowledgement Success of any project largely depends on the peoples associated with it. Their support, guidance and their encouragement bring up confidence in you. In this regard I really appreciate and thankful to all my colleagues and teachers who made me self confident and motivated for this project. My special thanks to Prof. Paul Junor who gives me tremendous support and help throughout this project .Without his support and guidelines I am never be able to withstand and take this opportunity to express my ideas in accordance with the project. The assistance and hold up acknowledged from all the members who have a say to this project, was imperative for the accomplishment of the project. I am indebted for their continuous support and help. 3 | P a g e
  • 4. CPAPs for Premature Infants 1.1.Introduction CPAPs (continuous positive air way pressure) is a mechanical mean to deliver air pressure to those patients who feels problem in normal breathing. It is a noninvasive technique which has been use for the decades of years. This technique of providing artificial breathing gives them an ease to support in their daily life. It may also enhance their life to be living healthy. An effective ,cheap and easy way to maintain a normal healthy life. This is not the limit, beyond it, this technique may also be involved in life saving activity for the premature infants as their immature lungs, sometime, are not capable to breath their own due to their weak intercostals muscles. for a while, this technique is use to increase the oxygen level in their blood by given them oxygen support with the same principle with a different source.[6] So the CPAPs becomes the multi diverse technique which not only helpful in adults but in preterm infants as well. It also have some vital role in therapy of disorders like sleep apnea, respiratory distress syndrome(RDS),dypnea and many more others.[3,4] Since the gestation period the struggle for survival starts. It is the natures’ tendency to support the one who struggles so as the theory of Darwin says “Survival of the fittest”. As soon the baby is out of mother’s womb it starts it new journey of life. Many are lucky to be out by the normal growth period but some aren’t; they face certain complications like chronic lung disease, developmental delay, hearing impairment, intraventricular haemorrhage and respiratory distress syndrome. These are some of the complication which is very high in neonates. As premature have a smaller lungs their ability of breathing rate is much higher than adults. They need a constant supply of air pressure depending on their gestation week / weight. To achieve this constant air supply which can improve the mortality rate of the premature we can use Ventilators, Continuous Positive Air Pressure’s and Bubble Continuous Positive Air Pressure’s. [1, 2] 1.2.Aim of the project Basically this project is design to minimize the complexity and the cost of the CPAPs so that it can be easily used in the developing countries like Ghana a state of Africa where the mortality rate is on increasing in preterm infants mostly because of respiratory problems and immature lungs. So there is a need of cheap machines which can easily be affordable and even can 4 | P a g e
  • 5. CPAPs for Premature Infants eliminate the cost of hospital expenses, power consumptions and its mode of operation is as simple as on one touch it can be operated. Considering all these options, we in Latrobe University trying to make such type of device which can be simple in use and should be easy in operation. The machine should be powered by any natural resource or a source which doesn’t require any consumable expenses. In this regard we are trying to make a respiratory control assit device called CPAPs (continuous positive airway pressure) which will work on Solar Power energy or any other renewable resource which can creates its own energy by applying any technology. 1.2.1.Why use CPAPs Continuous positive airway pressure (CPAPs) has been used in patients which have some particular respiratory problems, this included sleep apnea in which there is some disorders in breathing during sleeping which includes pause in breath for some seconds[28] , sleep disorders associated with heart failure, restrictive pulmonary diseases (decrease in total pulmonary capacity)[29] , severe stable chronic obstructive pulmonary disease, and the obesity- hypoventilation syndrome in which overweight people cannot breath well and this will cause decrease in oxygen concentration in blood with an increase of CO2 concentration[30] .In this regard, CPAPs has given dramatic change in significant physiological reimbursement, by improving the worth of life, and even longer survival in some of the cases. CPAPs with a nasal mask is therefore broad way to balance the increase folding of the air way.[7] CPAPs giving a constant positive air pressure to the patient during natural breathing by decreasing the work of breathing (WOB). It is use in cure of cardiovascular problems by treating in various obstructive disease of sleeping disorders. It also can be use for associated pulmonary disorders with congestive heart failures. Role of CPAPs in case of sleep apnea is really effective and even in case of premature infants is an undeniable fact. Because the lungs of preterm babies are very delicate and even it is quite different in shape as compare to an adult person. 2.1.Basic Physiology of respiratory system 5 | P a g e
  • 6. CPAPs for Premature Infants Lungs are the main respiratory organ of the respiratory system where all the main function of respiration has to be done. From exchange of gases to diffusion of gases into and from the blood, all process is taking place in this organ. Two main phenomenons which involve in the respiration process are; • Inspiration • Expiration In the process of inspiration ,atmospheric air is taking in through the nasal cavity from where it will enters into the pharynx. The pharynx has two openings or it has the common opening for food and air. The pharynx open into the larynx and esophagus, the air will enter into the larynx because the esophagus is the path of food. The larynx then enters into a long tube like structure called the trachea. The trachea and bronchi further divided into two bronchioles each of which enters in the two sets of lungs. This whole process is an active phenomenon while in case of expiration which is a passive procedure during a quiet breathing; the air which was taken in will be exhale out and gives the gas in return called CO2. Actually, the lungs are elastic in nature which can expand and contract during the entire process of respiration and the muscle involved in this mechanism are abdominal muscles called rectus abdominis, the intercostals muscles and the diaphragm. The rectus abdominal muscle provide support in a force breathing, mostly after a physical exercise or after doing some hard work. As lungs inflate and deflate the ribcage and abdomen increase and decreases. As volume and pressure are related, altering the lung volume changes the air pressure in lungs. • Increasing lung volume lowers air pressure(pushes ribcages & abdomen Outwards) • Decreasing lung volume higher air pressure(pulling ribcages & abdomen Inwards) Air flows from the region of higher concentration to the region of lower concentration, so air flows into lungs when pressure decreases below atmospheric level and out when pressure increases above atmospheric level. During Inhalation contraction of external intercostals muscle and diaphragm occurs and during Exhalation contraction of internal intercostals muscle occurs. 6 | P a g e
  • 7. CPAPs for Premature Infants Fig:1 Source: http://www.google.com.au/imgres?q=physiology+of+respiratory Considering the premature babies the lung and chest wall develop till 2-8 years of age. Below are the comparisons of the adult as well as healthy infant’s facts of lung state. 1. Alveolisation continues beyond infant age. • 20-50 million alveoli at birth in a healthy infant. • 300 million by age 8 years. 2. Increase in alveoli tends to increase in alveoli surface area. • 2.8 m2 at birth. • 32m2 at 8 years of age. • 75m2 at adulthood. 3. Ventilation through the pores of Kohn & Lambert Canal is not well developed in early years. 7 | P a g e
  • 8. CPAPs for Premature Infants 4. Lung matrix of the neonate contain small amount of collagen (elastin to collagen ratio changes during the 1st month & years of life which affects lung stiffness as well as potential for over distension & recoil. 5. Lung recoil (elastin) increases with age in children over 6 years of age. 6. Elastin recoil of an infant’s chest wall is close to zero & with age increases, because of progressive ossification of the ribcage & intercostal muscle tone. 7. Orientation of ribs is horizontal in infants & later by 10 years of age, the arrangement is downward. 8. Tongue is disproportionately large related to mouth. 9. Larynx is higher in neck(above Cervical4) [5,6] 2.1.2. Mechanism of Breathing The mechanism of breathing involves the process of diffusion. The phenomenons of diffusion define as; the movement of molecules from a region of higher concentration to a region of lower concentration and this is actually happening in case of breathing mechanism. The O2 is diffuses into the blood when we breath in because the concentration of O2 is lower in the blood as in alveoli so it will diffuse in the blood and the blood becomes oxygenated while the concentration of CO2 is higher at the same time in blood then in alveoli so it will diffuse in alveoli. This whole process is done by the breathing mechanism as we continuously taking in the fresh oxygen and passively given out the carbon dioxide. 8 | P a g e
  • 9. CPAPs for Premature Infants Fig: 2 Source: http://www.google.com.au/imgres In natural breathing, a pressure gradient is generated due to which the process of breathing occurred. Figure 2 demonstrating a diagrammatic view of the breathing mechanism that when we take air in, the volume of the lungs becomes increases which corresponds to the decrease of pressure in thoracic cavity which in results contracts the diaphragm outwards and also the chest becomes expended as demonstrated in Fig:2.Now due to low pressure inside the thoracic cavity and high atmospheric pressure the passive phenomenon of expiration would be occur to maintain the equilibrium condition and the diaphragm and chest would again be relax and the intra thoracic pressure again increases and this cycle continues throughout the life. 2.1.3. Motor pathways The diaphragm is the major muscle in the process of respiration which is creating the negative pressure due to which, the process of inspiration would be taken place. It is a thin sheet of muscle which will separate the thorax from the abdomen. Other muscles which are involve in the respiration process are the internal and external intercostals muscles.[27] 3.1. Artificial ventilators: 9 | P a g e
  • 10. CPAPs for Premature Infants It consists of a mask, an oxygen source and an air bag. There is a valve to separates inhalation and exhalation process. Air bag work as a manual pump for the continuous supply of oxygen. It is use for the temporary purposes. 3.1.2. Ventilators: They are usually design to work as human lungs or as an alternative of lung in case of pulmonary disorders. Ventilators have different modes which can be run-in accordance with type of disorder or according to the patient needs. Two basic ventilations are: Negative Pressure Ventilation: inspiration occurs because of negative pressure creates in pleural cavity because there is low concentration of air inside the pleural cavity and high concentration in the atmosphere. So –ve pressure ventilators are required. Positive Pressure Ventilation: when the concentration is much higher inside the pleural cavity, it will generate positive pressure in the pleural cavity so patient needs to expire. Positive pressure ventilators are used in wide range of disorders. It is frequently use in spontaneous mode where the patient required less effort to respire. While in case of compulsory breaths, ventilators controlling all the parameters like tidal volume, respiration rates, etc.These kind of breath are given to that patient who are unable to respire by their own efforts. 3.1.3.Types of Ventilator: Two types of ventilator are: Anesthetic Ventilator: It refers to use during operation or surgery when the patient is in unconscious state. Intensive Care Ventilator: In this air is delivering to the patient for inhalation. This type will give the precise control for the respiration process. Terminologies Used In ventilation: 10 | P a g e
  • 11. CPAPs for Premature Infants Fig:3 Source: http://www.google.com.breathing+mechanics+inspiration+and+expiration 3.1.4.Lung Compliance: It is actually the ability of lungs and alveoli to expand on delivering a certain or required amount of gas. It is usually in liter/cmH2O.It also refers to change in volume of the gas inside the lungs. 3.1.5.Airway Resistance: It is resistance in flow of air during the entire process of respiration which will get increase in bronchioles because of its smaller diameter. 3.1.6.Mean Airway Pressure: It is basically the pressure of the air between aspiratory and expiratory phase. Aspiratory Pause Time: This phase will occur when the alveolar pressure becomes equal to the patient circuit. On that phase there is no flow of gas is taking place, so there is a time interval or a pause state which is called as pause time. 3.1.7.Tidal Volume: It is the total time inspired and expired during each breathing cycle. It can be calculated by getting the product of flow rate and inhalation time. Respiratory rate: Number of breath per second. 11 | P a g e
  • 12. CPAPs for Premature Infants Assist control mode and SIMV mode: In these modes ventilator actually measures the breath by taking an average of previous four breaths. CMV: conventional mechanical ventilation is providing a forced ventilation to achieve normal breathing. It determines the tidal volume at a respiratory frequency. IMV: Time delay between each breath. 4.1.Effect of CPAP: The CPAPs has been used to overcome the problems related with respiration process. It helps in maintaining the oxygenation in blood and playing a vital role in decreasing the airway resistance during the process of breathing mostly in premature infants. It also helps in increasing functional residual capacity and has the tremendous effect on the immature lungs of preterm babies. CPAPs maintain the air pressure in the lungs by giving a constant amount of pressure in accordance with the required pressure. This is the beauty of this device that it has been designed as for the patient needs. CPAPs therapy helps in maintaining the transpulmonary function of lungs by increasing the functional residual capacity and thus by decreasing the bulk requirement of oxygen. It also • recover lung compliance • decrease airway resistance • lessen the work of breathing • enhance the ventilation-perfusion percentage. 4.1.2.Effect on Cardiovascular Stability: High pressure of CPAPs can have a harmful effect on the cardiovascular system. The continuous or high pressure of CPAPs results in compressing the heart vessels of right sides which in return, will result in the decreased cardiac output due to which the amount of oxygen which is needed by the tissues of different organs is not sufficiently supplied. The major problem is with the decrease cardiac output which will then subjected towards acidosis and causing the problem with low blood pressure[14] .In this case , the practice with the low pressure of CPAPs is highly recommendable[15] .However, sometime even the lower pressure becomes the cause for distress in 12 | P a g e
  • 13. CPAPs for Premature Infants respiration and can cause some severe adverse effects. So it is quite necessary for the operator to having a good familiarity with the level and standard pressure of CPAPs. In case of preterm infants, one should have to be well known with limitations of their immature lungs otherwise it may lead towards some severe degree of illness [14,17] . 4.1.3.Effect of CPAP in Pulmonary Function: Heart is the main pumping organ of the body through which the blood pumps throughout the body. The heart will serves as a motor which plays an important role to maintain homeostasis of the blood flow. When this pumping organ becomes unable to pump blood due to any disorder, this will cause heart failure or congestive heart failure (CHF). Contrary of advancement in medical sciences, this problem will remain the major cause of increasing mortality rate related with the failure of heart. One of the major effect of CHF is because of lungs dysfunction in which the fluidic concentration (lung edema) becomes increases which in turn will give rise to muscles fatigue in performing routine exercises.[21] One of the way to reduce or to control the pulmonary edema is by giving the relatives drugs or by supplying forced Oxygen to patient in order to improve the performance of myocardial muscles followed by the oxygenation. But sometime the crucial respiratory failure would be occur and the only chance for survival will be the mechanical ventilation. The other way to get avoided with these kind of disease in a very initial stage is by providing the CONTINOUS POSITIVE AIRWAY PRESSURE which has been used from a long time to those patients[13,17]. .By applying a constant positive air pressure will help to sustain oxygen concentration in the blood and helps to improves the lungs edema and the pulmonary function. This will also cause to decrease in respiratory work and work of breathing by decreasing in left ventricle preload and after load.[23,24] So the CPAPs may also be beneficial in use to increase the physical exercise capacity of the patients having congestive heart failures. Constant use of CPAP for two weeks enhances the stability of the pulmonary function with an increase stability of the regular exercise. CPAPs therapy is helpful in maintaining the cardiac output in consideration with the treatment of CHF 13 | P a g e
  • 14. CPAPs for Premature Infants patients it shows a favorable result which implies that CPAP may not only use for the cure of disease with heart and lung but it may also increase the tolerance associated with the physical exercise. In a nutshell, it is quite clear that CPAP therapy not only enhances the cardiopulmonary functions but it is equally helpful in increasing the capability of regular exercise.[23] 4.1.4.Effect On Central Nervous System CPAPs therapy as in relation with their effects on nervous system reveals some adverse effects. It may increase the intracranial pressure which may results to decrease in arterial pressure or the blood pressure and this will cause to reduce the cerebral perfusion pressure. Intracranial pressure is actually the pressure gradient of the brain tissues. In a supine position this pressure is 7 to 10 mmHg while in vertical position it becomes -10mmHg.As in case of CPAPs therapy the intracranial pressure shows some variation with the type of CPAPs delivered i.e. in HeadBox type it is showing a higher pressure rather in nasal prong or endotracheal one. It has been proved that the high pressure of CPAPs influence the central venous pressure by increasing it and this will cause an increase concentration of CO2 with a decrease level of O2 in blood, particularly when it comes near to 8cmH2O.[31] 5.1.Types of CPAP : 5.1.2.Critical care ventilators. This type of CPAPs have a high capacity to produce air flow as required by the patient. It may really helpful for the cure of acute respiratory distress as compare to the portable CPAPs but the problem with this type is its large size and complications in operation because even its monitoring console is quite complicated as the basic aim of CPAPs is its ease of use, particularly in the noninvasive techniques. Moreover, the device is quite expensive as compare to portable one and heavy in weight which may interfere in handling.[32] 5.1.3.Boussignac CPAP system 14 | P a g e
  • 15. CPAPs for Premature Infants This type of CPAPs system consists of a valve which controls the pressure of air flow. It is comprises of a plastic tube on-face mask valve which controls the air pressure, ranging from 2.5cmH2O to 10cmH2O.The valve itself control the flow without using any flow generator. The valve consist of a plastic tube with a length of 5.5cm and the internal diameter is about 1.3cm.This valve is attached to a face mask which then attach to the patients nasal cavity and mouth. The basic principle of this device works on the low pressure and high speed of oxygen molecules which then transformed into the high pressure flow and thus maintain the required pressure to be given. The device is user friendly and easy to use in operation, so it can be taken in an emergency procedure.[32] 6.1.Methods and Material The basic designing of this project is based on the following; 6.2.Power Source: The power source is the basic part of this project because we have to use the source other then the electrical; this means that whatever be the source it must have to be generating the power itself. It must not be the conventional which usually powered our homes. In this regard we were trying to use “Solar Power” in order to drive the rest of the circuit or may be some other mechanical or chemical energy of source. 6.2.1.Solar Power: Solar energy are the rays of sunlight which can be use to produce electrical energy by means of a device called the solar cell. This form of energy can be converted into electrical form by using photoelectric effect or photovoltaic effect. We can also concentrate this solar energy by using convex lenses so the resulted beam of solar energy is denser and thus generate more power. The two ways to create electric current and voltage is; • Photovoltaic effect • Photoelectric effect 15 | P a g e
  • 16. CPAPs for Premature Infants Sometime these two different processes will be considered as same but there is a slight difference in their generation of voltage. In Photovoltaic effect, using a semiconductor material which when placed in sunlight will direct emit the voltages. On the other hand, in photoelectric effect, transfer of electrons would be occur from the valence band to the conduction band and due to this change in energy level from higher to lower it will emits electron and thus the generation of voltage between two electrodes will be occur. Fig:4 Source:http://photovoltaics.sandia.gov/docs/PVFEffIntroduction.htm 6.2.2.How to build a solar module: Actually we can have directly purchase a solar module according to our required output. But we can also make a solar module by having assemblies of solar cells which are grouped together in series can make a solar module. This array or solar module can convert the sunlight energy into the electrical energy, as one solar cell can generate approx 0.5 mV of voltage so we can organize it as our required output which is about 12V. 6.3.DC Motor: 16 | P a g e
  • 17. CPAPs for Premature Infants Fig:5 Source: http://gilbertojunqueira.com/quick-motor-tip-of-the-day#more-51 A 12V DC motor with a wing will produce air which will then be passed to the pressure sensor through a small pipe commonly called as Neonates Cannula. The rotating speed of the motor is directly proportional to the voltage supplied. So we can also control the pressure of the air by controlling the rotational speed of the motor.[10] 6.4.1.Pressure Sensor This is the most important part of the project or the key area for the required output. Pressure sensor detects the current pressure of the air that is supplied from the fan through this we can control the pressure according to a preset value or can be programmed in either way. After the pressure is regulated, air is supplied to the tubing from which it will flow to the patient nostrils through nasal cannula or a breathing mask. 6.4.2.MPX2010 Pressure Sensor(COMPENSATED PRESSURE SENSOR) In this regard we find the MPX2010 pressure sensor is the most appropriate and its output voltage is directly proportional to the applied pressure. This pressure sensor will convert the air 17 | P a g e
  • 18. CPAPs for Premature Infants pressure into the voltage and we can easily manage the required air pressure by checking the output volts.[11] Characteristics and features • 0 to 10 kPa (0 to 1.45 psi) • FULL SCALE SPAN: 25 mV • Temperature Compensated over 0°C to + 85°C • Unique Silicon Shear Stress Strain Gauge • Ratiometric to Supply Voltage • Differential and Gauge Options Fig:6 Source: http://www.google.com.au/imgres?q=MPX2010 Application Examples • In Respiratory Diagnostics • Air Movement Control • Controllers • Pressure Switching Pin Configuration: 1 2 3 4 Ground +Vout Vs -Vout 18 | P a g e
  • 19. CPAPs for Premature Infants Where Pin 1 is a notched pin. Voltage Output V/s Applied Differential Pressure The output voltage is increase with an increase in pressure side P1 in relation with pressure side P2.likewise by raising the vacuum side P2 the voltage is also increases. The other characteristics of the device is mentioned in the data sheet which is not necessary to include in the report.[11] 6.5.1.Pressure ranges according to their Use: Low Pressure 2-3 cmH2O • Maintenance of lung Volume in very low birth weight infants • During weaning Medium Pressure 4-7 cmH2O • Increasing lung volume in surfactant deficiency • Stabilizing areas of Atelectasis • Stabilizing obstructive airway High pressure 8-10 cmH2O • Preventing lungs Collapse with poor lung volume • Improving distribution of ventilation Ultra High 11-14 cmH2O • Tracheal or bronchial collapse • In severe obstruction • Reestablishing lung volume during ECHO Table:1 So there are specific pressure ranges of air for the specified problems in the infants according to their difficulty need. These pressure are given to the patient according to the circumstances or in accordance with the degree of severances of disease.[12] 19 | P a g e
  • 20. CPAPs for Premature Infants 6.6.Flow Sensor: Flow sensor serves as an emergency signal to alert for a problem condition in air pressure. It monitors the air flow that is supplied to the patient, and outputs an emergency signal if the air pressure is not in the desired range. This terminal can be a enhancement for the project if we get the desired output. Fig:7 Schematic circuit of flow detector Source: http://www.google.com.au/imgres?q=air+flow+detector+circuit+diagram The Figure 7 shows the circuit of air flow detector. This circuit can give a visual indication of the rate of air flow. It can be also used to check whether there is air flow in a given space. According to the circuit in figure 7, we can use a filament of the bulb which can sense the air flow. When air is flowing through the filament the resistance will go on increasing because the passing air creates heat resistance, and when the flow of air will be stop the resistance across the resistor will be drop down because the air flowing will also removes the heat from the filament and this variation of drop voltage can be detected by the opam (LM339) and we can generate alarm or LED blinking as a signal in failure of air flow. 6.7.1.Nasal Prongs 20 | P a g e
  • 21. CPAPs for Premature Infants This device is consisting of plastic tube which will attach to the patient. It consist of two small tube called the prongs which will place in the patients nostrils as shown in the figure 8.The other tubular shape structured is connected to the air supply. Air flows from these prongs and the nasal cannula is connected to the supplied air by the dc motor. The nasal cannula carries 1–5 liters of air per minute or as desired. The nasal prongs are a device used to deliver supplemental airflow to the person in need of respiratory help. This device consists of a plastic tube which fits behind the ears, and a set of two prongs which are placed in the nostrils. Fig:8 Source: http://www.google.com.au/imgres?q=nasal+prongs The figure 8 show the typical Nasal Prong which is used in CPAP system. But some time it is not user friendly and some other kind of prongs are also be used. 6.8.Tubing: The tubing used to deliver air is about 10mm in diameter with a very low resistance in flow of air. This tubing is about 5 to 6 meter in length or depends on the circuit requirement. 7.1.1Procedure Power will be given to the DC motor in order to create air flow which will then be passed to nasal prong via tubing. There is a pressure sensor which control will monitor the pressure of the air. This pressure sensor shows the pressure of the air flow in volts and through this sensors output we will control the air flow by controlling the speed of the motor. Now this air is passing through the tubing supply to the patients nostrils via nasal prongs. A beaker with water with a 21 | P a g e
  • 22. CPAPs for Premature Infants graduated glass tube is connected to the expiratory tube ,which comes from the patient nostrils .The function of this expiratory tube is to control the air pressure. The graduation is marked in cmH2O.T his metal tube allows gas to exhaust into the water, and pressure will assorted by adjusting the depth of the tube in water. The Flow sensor circuit is continuously monitoring the air flow to the patient and in case of failure of air flow it gives an alarm to check out the problem. 8.1.1.Cost Evaluation The total cost which is given by the university is about 400$.i.e 200$ for each student. The approximate cost for this project if it is undertaken in the present circumstances is given below. Component Price in AUD$ DC Motor ~16.00$ Solar Pannel ~40.00$ Rechargeable Battery ~ 25.00$ Tubing Giving by the hospital Nasal Prongs Giving by the hospital Flow Sensor ~34.00$ Air Detector Circuit ~12.00$ Other cost ~30.00$ Table:2 8.1.2Other Ideas: During this project I have went through some other interesting ideas which can make this project simpler and easier in use but most of them are quite unprofessional and may kill the idea of cheap cost. So I don’t discuss about those ideas. But one idea that clicks to my mind and is quite good in my perspective is; 22 | P a g e
  • 23. CPAPs for Premature Infants • A simple way to charge the battery is by using a small dynamo, turned by the DC Fan motor through a belt. Fig:9 Source: http://www.google.com.au/imgres?q=Dc+motor+use+to+charge+the+12v+battery The Figure 9 depicts one of my idea to generate the voltages through the same DC motor which we will use to generate the air flow for the patient. In this, we can use two sets of DC motor and by using a belt we can attach the axle of both the motors with each other. The one which will take the power from the battery will generate the air flow and through this the axle of the other motor will also be rotate creating the voltage on its input. Now this voltage can be use to charge the same battery which is giving power to the first motor. 8.1.3.Discusssion: The CPAP system which we want to design and implemented is a feasible project to design. But it may take some more time and enhancements in its features and cost. Approximately the research work has been done to implement the idea. In the report all the physiological and technical parameter has been discussed. It is better to implement the idea in consideration with the basic aim of this project which is the cost effectiveness and the simplicity. Because as we 23 | P a g e
  • 24. CPAPs for Premature Infants know this is not a new invention but the same invention and basic principle with some new advancement so that it can be use to lower down the mortality rate of premature infants in some developing countries. One other aspect of this project is that it must be user friendly and the operation of the system must be simple so that it can easily operated even at home without any hesitation. Conclusion In a nutshell, the idea is ready to implement with some more advancement. The hardware is not completed yet. This project is quite useful as it is power saving and regardless of expenses. The natural resources are use to power the module and can easily be use in developing countries. 24 | P a g e