Bionanotechnology market research report

RITMIR011: Bionanotechnology – A Market Insight Report, July 2013
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BIONANOTECHNOLOGY MARKET SIZE
Scope of the Study
Bionanotechnology report gives an insight into the global market for the rapidly growing industry of
Bionanotechnology, the science of the future. The study provides global market analysis for
bionanotechnology by application in Food, Drug Discovery & Development, Diagnostics Tools & Devices,
and Other. The study includes estimates and projections (2005-2012) for the global Bionanotechnology
market. Projections and estimates are also illustrated by geographic region encompassing North America,
Europe, Japan, Asia-Pacific, Israel and Rest of World.
Business profiles of 40 major companies are discussed in the report. The report serves as a guide to global
Bionanotechnology industry, as it covers more than 522 companies that are engaged in Bionanotechnology
R&D, discovery, testing and supply of products and services. Major Contract Research Organizations and
Universities serving Bionanotechnology industry are also covered in the Corporate Directory section of this
report. Information related to recent product releases, product developments, partnerships, collaborations,
and mergers and acquisitions is also covered in the report.
Bionanotechnology report is an ideal research tool providing strategic business intelligence to the
corporate sector. This report may help strategists, investors, laboratories, pharmaceutical companies,
contract research organizations, biotechnology companies and drug approval authorities in-
 Gauging Competitive Intelligence
 Identifying Key Growth Areas and Opportunities
 Understanding Geographic Relevance to Product
 Knowing Regional Market Sizes and Growth Opportunities and Restraints
 Keeping Tab on Emerging Technologies
 Equity Analysis
 Tapping New Markets
Analytics and data presented in this report pertain to several parameters such as -
 Global And Regional Market Sizes, Market Shares, Market Trends
 Product (Global And Regional) Market Sizes, Market Shares, Market Trends
 Technology Trends
 Corporate Intelligence
 Key Companies By Sales, Brands, Products
 Consumer Behavioral Patterns

 Other Strategic Business Affecting Data
Research Methodology
RI Technologies publishes business intelligence reports by going through a cycle of diligent research and
analysis activity. Research is done using both online and offline resources. The study outline of this report is
sketched on the following lines - global market analysis, regional market analysis, product segmentation,
global and regional market analysis by product segment, market trends, M&A, R&D, competitive landscape,
technology trends, and other key drivers. Current data helps in analyzing the future of the industry and is
also helpful for doing market evaluations, and estimating the market size for the future.
This report is uniquely researched and the methodology includes:
 Need and Scope of Study
 Product Definitions
 Segmental Analysis
 Regional Analysis
 Exclusive Data Analytics
 Corporate Intelligence
 Feedback
Right from concept to final compilation of this report, both primary and secondary research methods are
applied. We have provided exclusive feedback forms/pre-release questionnaires for this report to use the
information for authentication of our own findings. Secondary research includes government publications,
investment research reports, web based surveys, website information of both companies and markets, and
other offline resources such as print publications and CDs.
Our compilation of easy to navigate PDF reports are essential value addition resources for leading and
growing companies.

II. REPORT SYNOPSIS
Nanotechnology
Nanotechnology is the technology that deals with minute matter – nanometers, that measure to 1 billionth
of a meter. The technology is developed at the atomic, molecular, or macromolecular range (1-100
nanometers) for creation of novel products. The word “nano” originates from the Greek word - nãnos that
means “dwarf”. Any technology that deals with nanometers is called as nanotechnology.
Bionanotechnology
Bionanotechnology is the interface between the chemical, biological and the physical sciences. It is
concerned with nanometer scale systems that may be produced from a top down approach, where larger
units are disassembled, or a bottom up approach involving component assembly. Utilizing nanofabrication
and or processes of molecular self-assembly, nanotechnology allows the preparation of a range of materials
and devices including tissue and cellular engineering scaffolds, molecular motors, and arrays of
biomolecules for sensor, drug delivery and mechanical applications.
Bionanotechnology is a branch of biotechnology that uses nano-sized tools and templates for executing
some biological function. A process that uses biological systems for developing nano-sized systems is also
referred to as nanobiotechnology. Therefore, Bionanotechnology can be said to be use of nanotechnology
in biological processes, and use of biological processes in nanotechnology.
The technology integrates the underlying concepts of physics, chemistry, and biology in molecular and cell
biology. There are two ways of devising Bionanotechnology tools. Larger sized biological systems can be
broken down to their nano-sized levels. Alternately, atomic and molecular matter may be fabricated or
assembled into a biological tool that is confined to a size of 1-100 nanometers.
Such fabrication or self-assembly of atoms and molecules are molecular nanotechnology processes. These
processes are used to create a wide range of materials and devices such as cellular engineering scaffolds,
cell membranes, drug delivery tools, virus particles, and arrays of biomolecules identifiable by sensor, etc.
Some of these devices help in understanding the complexity in biosystems.
Bionanotechnology, a science of the future, is a major research area in recent times and for the future as
well, gaining importance in medicine and to an extent in other areas of research. It is a science which deals
with operations at a scale which is billionth of a meter. These nano machines are modified biological
entities which are driven by a motor (for energy). These nanomotors fetch various uses for our body like,
the identification of pathogens, activating the immune system, automatic drug delivery system, fixing the
host cells, destroying the infected and the injured cells etc,. Some machines are fitted with high intensity
lasers to destroy the infected cells (like the RBC in case of malaria).
This technology is now a major research field for medical doctors, biologists, chemists, physicists, and
engineers. Researchers are hopeful that Bionanotechnology will someday help in creating biological systems.
Nanobiomechanics
Nanobiomechanics is that branch of biomedical technology that evaluates the mechanical qualities of each

living cell. For such measurement, instruments that detect, produce, and gauge forces as faint as few
piconewtons (1 picotnewton = Newton/trillion) are used.
Nanobiomechanics have become a very important aspect of nanotechnology related biomedical research.
The technology is used for diagnosing a disease, and developing new types of treatment for the disease.
The process entails identification of physiological changes in individual cells caused by the disease, and
finding ways and means to correct these changes. For example, Malaria is caused by a parasite, which
reduces the flexibility of red blood cells in patients. As of now, the disease is only treated, but there are no
cures. Nanobiomechanics may show new method for treating such diseases.
Biomolecular Nano Technology
Definition: Synthetic technology based on the chemical pathways and principles that govern living
organisms is known as Biomolecular Nanotechnology. The said living organisms could range from genetic-
engineered microbes to even custom-made organic molecules. The scope of Biomolecular Nanotechnology
covers the study, creation, and illumination of the connections between structural molecular biology and
molecular nanotechnology. This is because the development of nano-machinery may be guided by studying
the function and structure of the natural nano-machines which are present in living cells.
Bionanotechnology attempts to modify and search for technological uses of natural nano-components like
the nano-motors of ATP synthase and develop the use of scaffolds of the enzyme complex of cellulosomes
for the addition of new enzymes to produce nanosomes.
An astounding prediction was made in 1965 that the number of transistors that could be placed in a given
area would double every eighteen months for the next ten years. The trend has passed the ten years mark
and this phenomenon known as The Moore’s Law still continues. In 1971 there were 2,000 transistors in
the original 4004 processors. Now in the Pentium 4 there are 40 million transistors. There has been a
corresponding decrease in the size of individual electronic elements. In the 1960s the size was in
millimeters whereas in present-day electronic circuitry it is measured in hundreds of nanometers. The
person who propounded the Moore’s Law was none other than Gordon Moore who was one of the
founders of Intel Corporation.
The trend goes in the opposite direction when it comes to chemistry, biochemistry and molecular genetics
communities. In the same time period, it is seen that it is possible to direct the synthesis of larger and more
complex structures up to tens or hundreds of nanometers in size. This holds true irrespective of whether it
is in the test tube or in modified living organisms. Enzymes are the molecular devices which is the driving
force behind life. Presently the manipulation of the structures and functions of these systems in vivo is
possible and the building of complex biomimetic analogues in vitro has also become viable.
During the last quarter of the century enormous advances have been made in the ability to control and
manipulate light. Light can be measured for size and this size is on the hundred nanometer scale. The easy
availability of solid state lasers has seen the costs of the same coming down drastically. The generation of
light pulses as short as a few femtoseconds is now possible. The imaging of light is possible through the use
of computers. Through fiber optics the noiseless sending of information at bandwidths of many gigabytes is
now a reality.
With the dawning of a new century, three powerful technologies have been brought together on a
common scale which is called the nanoscale. This promises to cause a revolution in the fields of biology and
electronics. This new field which is known as biomolecular nanotechnology holds a promise of many

possibilities from fundamental research in molecular biology and biophysics to the innumerable
applications in medicine, computing, information storage, energy conversion, biosensing, biocontrol and
genomics.
The ultimate example of nanotech is life itself. Considering this fact the possibilities of what lies ahead is
truly exciting.
Segmentation of Bionanotechnology
Global Bionanotechnology market is segmented by application area into Food, Drug Discovery and Delivery,
Diagnostics, Devices and Tools, Bionanosensors, and Other.
Exhibit 1. Segmentation of Global Bionanotechnology Market by Application
Application
Food
Drug Discovery and Delivery
Diagnostics
Devices and Tools
Bionanosensors
*Other
© RIT, 2013

Global Market Analysis
Global Bionanotechnology market is projected to reach about US$XX.XX billion by 2020 from an estimated
US$ XX.XX billion in 2012, growing at a compounded annual growth rate (CAGR) of XX.XX % during the
analysis period 2005-2020.
Exhibit 2. Bionanotechnology – Global Value Market Estimations & Predictions (2005-2020) in US$ Million
Year Value
2005 XX.XX
2006 XX.XX
2007 XX.XX
2008 XX.XX
2009 XX.XX
2010 XX.XX
2011 XX.XX
2012 XX.XX
2013 XX.XX
2014 XX.XX
2015 XX.XX
2016 XX.XX
2017 XX.XX
2018 XX.XX
2019 XX.XX
2020 XX.XX
CAGR% XX.XX
© RIT Figures, 2013
2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020
US$ Million

III. MARKET DYNAMICS
Market Overview
Bionanotechnology has its major role in the nanomedicine field, i.e. drug delivery process. In disease
diagnosis, the growth is driven by the use of nanoparticles in different areas, for example, in the
identification of the affected cells as in cancer and during the chemotherapy process nano particles are
used to treat only the affected cells without affecting the normal ones.
Bionanotechnology helps to reduce the hospitalization stay and cost burden on the patient. By introduction
of novel products, newer designs and devices-all aimed to offer better healthcare to patient.
Bionanotechnology is playing a key role in clinical diagnosis i.e. they help in diagnosis of disease even
before the symptoms are observed. Bionanotechnology helps to treat only the affected cells without
affecting the normal cells.
There is wide scope for Bionanotechnology in developing implantable devices suitable for in vivo diagnosis,
a few of which are mentioned below.
 A tablet like device that can be swallowed will transmit the internal images as it passes through the
food tube. This will replace the conventional endoscope.
 A nanosensor implanted into catheters can transmit valuable data to the doctor performing surgery.
 A miniature device implanted into the blood vessel will continuously monitor the blood glucose level in
the diabetic patients.
 A nanodevice that will respond to the extraneous molecules circulating in the blood will help early
detection of diseases like AIDS.
Such nanodevices will have tremendous market value, provided, they are compatible with the tissues
where they are implanted, capable of transmitting data and amenable to remote control. Future research
in Bionanotechnology should focus on engineering these devices to diagnose pathological tissues as well as
remove or rectify them. Invention of such devices would make invasive surgery a practice of the past.
Global Market Analysis
Global market for Bionanotechnology is projected to reach about US$ XX.XX billion by 2020 from an
estimated US$ XX.XX billion in 2012, growing at a Compounded Annual Growth Rate (CAGR) of XX.XX %
during the analysis period, 2005-2020. North America is the largest market for Bionanotechnology and is
projected to reach US$ XX.XX billion by 2020 to retain its lead position with a market share of XX.XX %.
Europe is projected to be the second largest (XX.XX % of market share in 2020) and second fastest growing
(XX.XX % during 2005-2020) market during the same analysis period, while Israel is projected to be the
fastest growing (XX.XX % during 2005-2020) market. In 2012, the market for Bionanotechnology in Europe
and Asia-Pacific was estimated at US$ XX.XX billion and US$ XX.XX million respectively.

Exhibit 3. Bionanotechnology - Global Value Market Estimations & Predictions (2005-2020) by
Geographic Region for North America, Europe, Japan, Asia-Pacific, Israel, Rest of World in US$ Million
Year/Region North America Europe Japan Asia-Pacific Israel RoW Total
2005 XX.XX XX.XX XX.XX XX.XX XX.XX XX.XX XX.XX
CAGR% XX.XX XX.XX XX.XX XX.XX XX.XX XX.XX XX.XX
2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020
US$ Million
North America Europe Japan Asia-Pacific Israel RoW

Global Market for Bionanotechnology Applications
Global market for Bionanotechnology applications market is projected to grow at a CAGR of XX.XX % during
2005-2020 to reach US$ XX.XX billion by 2020 from a reported US$ XX.XX billion in 2012.
The market for Devices and Tools market is projected to be the fastest growing segment during the period
2005-2020 with a CAGR of XX.XX %, while Drug Discovery and Delivery is estimated as the largest segment
in terms of market value in 2012 at US$ XX.XX billion.
Exhibit 4. Bionanotechnology – Global Value Market Estimations & Predictions (2005-2020) in US$ Million
for Food, Drug Discovery and Delivery, Diagnostics, Bionanosensors, Devices and Tools, and Other
Year/Application Food
Drug Discovery
& Delivery
Diagnostics Bionanosensors
Devices &
Tools
Other Total
CAGR% XX.XX XX.XX XX.XX XX.XX XX.XX XX.XX XX.XX
2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020
US$ Million
Food Drug Discovery & Delivery Diagnostics Bionanosensors Devices & Tools Other

BIONANOTECHNOLOGY – MARKET OUTLOOK
Global Bionanotechnology market is projected to grow at 35.75%, compounded annually from 2005
through 2020. This growth would be driven especially by application of bionanotechnlogy in Diagnostics,
Food, and Drug Discovery & Development.
Nanotechnology is expected to help in the early diagnosis of different diseases such as in the diagnosis of
the individual cancer cells than using other conventional methods of diagnosis that usually require
hundreds of cells to be present. Targeted drug delivery systems, an improved method of drug delivery using
nanotechnology, have the advantage of being able to administer drugs more easily and effectively. This in
turn not only extends the life of the drug, but also improves patient compliance while reducing healthcare
costs. Usage of nanotechnology in food packing not only increases the shelf life of food material but also
helps the retail owners and customers in evaluating the quality of the product. Asia-Pacific with more than
50% of world population is expected to become the biggest market for nano food with China in the leading
position.

IV. PRODUCT/TECHNOLOGY RESEARCH
The progress in Nanotechnology has been leading to the development of super-high-density data storage
and super-high-speed microprocessors, memory chips and novel nanodevices. Apart from
micro/nanoelectronics, nanotechnology is also finding a wide range of applications in many other areas
such as medical industry, clean chemistry and the aerospace industry. Nanoscience concerns a basic
understanding of physical, chemical, and biological properties on atomic and near-atomic scales.
Nanotechnology, narrowly defined, employs controlled manipulation of these properties to create
materials and functional systems with unique capabilities.
Definition
Nanotechnology can be broadly defined as a tool for engineering the matter at atom level or designing a
device with atomic precision. However, the definition may vary depending on the field of application.
Any device measuring below 100 nm falls under nano category. The properties of a material drastically
change when reduced to nanoscale below its critical size, and it marks a transition from classical to
quantum-mechanical range.
A nanodevice can be produced either by reducing a large structure step by step into smaller and smaller
one to achieve the nanoscale, or starting from atoms or molecules it can be gradually built up. The former
‘top down’ approach utilizes etching and machining methodologies. The latter ‘bottom up’ approach
involves nanomanipulation and directing the building blocks to undergo self-assembly in the desired
pattern. The central theme of nanotechnology is that any chemically stable structure can be built according
to the desired specifications.
The History of Nanotechnology
The word ‘Nano’ refers to midget in Greek, meaning, extremely small measuring one billionth. The term
‘nanotechnology’ was coined by Norio Taniguchi of the University of Tokyo in 1974 to signify the
technology pertaining to submicron size. The idea was developed by Richard Feynman much earlier in 1959
itself. He perceived the feasibility of manipulating matter atom by atom. Though it can be appreciated as
the first ever scientific thought on nanotechnology, the credit goes to Eric Drexler, who made Molecular
nanotechnology popular in his book entitled “Engines of Creation” written in 1986.
By this time, Richard Smalley and Harold Kroto of Rice University synthesized a molecule made up of sixty
carbon atoms. Its structure resembled a soccer ball simulating the geodesic domes built by R.Buckminister
Fuller. Hence this molecule was named as Buckminsterfullerene, shortly designated as “fullerene” or
“buckyball”. This strange molecule was produced by Richard Smalley and his coworkers by condensing
carbon vapors in an inert gas, and this work won them the coveted Nobel Prize for Chemistry in 1996.
Meanwhile, in 1991, Sumio Iijima discovered a nanotube made of carbon atoms exclusively. It looked as
though a sheet of carbon hexagons is rolled into a tube or the buckyball is pulled into a cylinder. The
nanotube possessed the properties of either a metal or a semiconductor depending upon the way the
edges of this sheet are joined to form a tube. It should be mentioned here that it is this discovery of
nanotube that revolutionized the designing of nanodevices at a later stage.

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 Identifying Key Growth Areas and Opportunities
 Understanding Geographic Relevance to Product
 Knowing Regional Market Sizes and Growth Opportunities and Restraints
 Keeping Tab on Emerging Technologies
 Equity Analysis
 Tapping New Markets
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