Intravenous solutions market research

RITMIR015: Intravenous Solutions – A Market Insight Report, July 2013
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INTRAVENOUS SOLUTIONS MARKET SIZE
Scope of the Study
Intravenous Solutions report covers the types of Intravenous Solutions and the various nutrients present in
Intravenous Solutions in the market. The types of Intravenous Solutions covered include Partial Parenteral
Nutrition and Total Parenteral Nutrition. The nutrients present in Intravenous Solutions include
Carbohydrates, Salt and Electrolytes, Minerals and Vitamins, Amino Acids and Other (such as Fat Emulsions,
Plasma extenders, Antibiotics and IVIG). The report provides an in depth analysis of each of the types and
nutrients by their respective categories. The study includes estimates and projections for the total global
Intravenous Solutions market and also key regional markets that include North America, Europe, Asia-
Pacific and Rest of World. Estimates and projections are illustrated graphically.
Business profiles of 16 major companies are discussed in the report. The report serves as a guide to global
Intravenous Solutions industry, as it covers more than 140 companies that are engaged in the development
and supply of Intravenous Solutions products and services. Information related to recent product releases,
product developments, partnerships, collaborations, and mergers and acquisitions is also covered in the
report.
Intravenous Solutions report is an ideal research tool providing strategic business intelligence to the
corporate sector. This report may help strategists, investors, laboratories, pharmaceutical companies,
contract research organizations, biotechnology companies and drug approval authorities in –
 Gauging Competitive Intelligence
 Identifying Key Growth Areas and Opportunities
 Understanding Geographic Relevance to Product
 Knowing Regional Market Sizes and Growth Opportunities and Restraints
 Keeping Tab on Emerging Technologies
 Equity Analysis
 Tapping New Markets
Analytics and data presented in this report pertain to several parameters such as –
 Global and Regional Market Sizes, Market Shares, Market Trends
 Product (Global and Regional) Market Sizes, Market Shares, Market Trends
 Technology Trends
 Corporate Intelligence
 Key Companies By Sales, Brands, Products
 Consumer Behavioral Patterns
 Other Strategic Business Affecting Data

Research Methodology
RI Technologies publishes business intelligence reports by going through a cycle of diligent research and
analysis activity. Research is done using both online and offline resources. The study outline of this report is
sketched on the following lines – global market analysis, regional market analysis, product segmentation,
global and regional market analysis by product segment, market trends, M&A, R&D, competitive landscape,
technology trends, and other key drivers. Current data helps in analyzing the future of the industry and is
also helpful for doing market evaluations, and estimating the market size for the future.
This report is uniquely researched and the methodology includes:
 Need and Scope of Study
 Product Definitions
 Segmental Analysis
 Regional Analysis
 Exclusive Data Analytics
 Corporate Intelligence
 Feedback
Right from concept to final compilation of this report, both primary and secondary research methods are
applied. We have provided exclusive feedback forms/pre-release questionnaires for this report to use the
information for authentication of our own findings. Secondary research includes government publications,
investment research reports, web based surveys, website information of both companies and markets, and
other offline resources such as print publications and CDs.
Our compilation of easy to navigate PDF reports are essential value addition resources for leading and
growing companies.

II. REPORT SYNOPSIS
At times, patients may suffer from severe loss of acids, salts, vitamins, and other nutrients. In such cases, it
is essential to correct such losses through direct infusion of these elements into the blood stream, a
process referred to as intravenous feeding. In most cases, IV infusion is used for short periods of time. It
may be used to help a patient recover from injuries or surgeries involving the face, mouth, esophagus,
stomach, and small intestine. During intravenous feeding, fluids containing vital nutrients are infused into a
peripheral vein (usually in the arm) via the drip mode. The bottle of fluid is placed on a stand above the
patient and connected via a plastic tube to a needle inserted in the vein. However, if this procedure is used
for longer periods in patients who are incapable of food intake via the mouth or a stomach tube, it may
prove to be dangerous, expensive, and time consuming. Intravenous feeding on a long-term basis is
possible if the plastic tube is inserted into one of the larger central veins of the patient. A wide variety of
intravenous solutions are available containing essential fats, amino acids, and glucose. They can provide
sustenance for weeks on end and even for years if required.
Intravenous feeding is the short-term administration of supplementary nutrients through a solution that is
introduced into the vein. Peripheral intravenous feeding refers to infusion of the fluid in a small vein on the
surface of an arm, leg or the scalp. On the other hand, central venous feeding refers to infusion into a large
vein which is embedded deep within a body. Only limited quantities of nutrients can be administered
through peripheral intravenous feeding as there is the danger of incurring phlebitis and/or clots (thrombi) if
concentrated solutions are used. However, in central venous feeding it is possible to infuse concentration
nutrient solutions as the rapid blood flow in the central veins can promptly dilute the solution thereby
minimizing the possibility of causing irritation to the vein.
Definitions
Intravenous
When a needle is inserted into a vein in the back of the hand, inside the elbow, or some other location on
the body such that fluids, nutrients, and drugs can be injected it is known as Intravenous administration.
Intravenous Infusions
Intravenous infusions are Solutions which consist of water of the highest quality, purity and sterility, to
which specific additives such as sugar, saline, medication, etc are added for medicinal purposes.
Intravenous infusions are also known as intravenous drips, intravenous Solutions or IVs, or Large Parental
Volume Solutions (LPVS).
Intravenous infusions are used in hospitals and clinics worldwide to provide patients with a constant source
of fluids, medication or nutrition intravenously. In most countries Intravenous Solutions are used as the
first course of action on injured or ill patients in the hospital.
Parenteral
Parenteral nutrition is the nutrition administered through the veins of the circulatory system, rather than
through the digestive system.
Enteral
Enteral Nutrition is a way to provide nutrition through a tube placed in the nose, the stomach, or the small

intestine.
Home Parenteral Nutrition (HPN)
When long-term parenteral nutrition, is given through a central venous catheter and is administered in the
patient's home it is known as Home Parenteral Nutrition
Partial Parenteral Nutrition (PPN)
A solution, containing some essential nutrients, is injected into a vein to supplement other means of
nutrition, usually a partially normal diet of food.
Total Parenteral Nutrition (TPN)
A solution containing all the required nutrients including protein, fat, calories, vitamins, and minerals, is
injected over the course of several hours, into a vein. TPN provides a complete and balanced source of
nutrients for patients who cannot consume a normal diet.
Benefits:
The main benefits of administering intravenous solutions through the peripheral veins are:
 Solutions can be customized to meet the requirements of the patient.
 The requisite nutrients are quickly administered directly into the bloodstream. Thus the patient is sure
of getting the nutrients in the required areas. The uncertainties governing the appetite of the patient
and the ingestion, digestion and absorption of the intravenous feed are no longer matters of concern
in this case.
 Nurses and paramedics are qualified to administer peripheral vein infusions. However, only a doctor
can administer total parenteral feeding through a central vein.
Hazards of Intravenous Feeding
The main hazard posed by supplementary intravenous feeding infused through a peripheral vein is when
the feed is administered in large quantities too rapidly without assessing the patients’ condition.
Intravenous feeding administered through a peripheral vein should be avoided in the following cases:
1) If feeding either orally or via a tube satisfies the nutritional requirements of the patient
2) If intravenous administration is required on a long-term basis and TPN is available.
3) If the patient’s condition is unstable and the risks involved in intravenous feeding are far more than the
benefits that can be derived from it. In such cases, intravenous feeding can be started as soon as there
is stabilization in the patient’s condition.

Segmentation of Intravenous Solutions
Exhibit 1. Segmentation of Intravenous Solutions Market by Type (Partial Parenteral Nutrition and Total
Parenteral Nutrition) and Nutrients (Carbohydrates, Salt & Electrolytes, Minerals & Vitamins, Amino
Acids and Other)
Type Nutrients
Partial Parenteral Nutrition Carbohydrates
Total Parenteral Nutrition Salt and Electrolytes
Minerals and Vitamins
Amino Acids
*Other
*Other includes Fat Emulsions, Plama Extenders, Antibiotics and IVIG
© RIT, 2013

Global Market Analysis
Global Intravenous Solutions market is projected to reach about US$ XX.XX billion by 2020 from an
estimated US$ XX.XX billion in 2012, growing at a compounded annual growth rate (CAGR) of XX.XX %
during the analysis period 2005-2020.
Exhibit 2. Intravenous Solutions– Global Historic Value Market (2000-2005) in US$ Billion
Year Total
2000 XX.XX
2001 XX.XX
2002 XX.XX
2003 XX.XX
2004 XX.XX
2005 XX.XX
%CAGR XX.XX
© RIT Figures, 2013
2000 2001 2002 2003 2004 2005
US$ Billion

Exhibit 3. Intravenous Solutions – Global Value Market Estimations & Predictions (2005-2020) in US$
Billion
Year Value
2005 XX.XX
2006 XX.XX
2007 XX.XX
2008 XX.XX
2009 XX.XX
2010 XX.XX
2011 XX.XX
2012 XX.XX
2013 XX.XX
2014 XX.XX
2015 XX.XX
2016 XX.XX
2017 XX.XX
2018 XX.XX
2019 XX.XX
2020 XX.XX
CAGR% XX.XX
2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020
US$ Billion

III. MARKET DYNAMICS
MARKET OVERVIEW
Economic Profile
When IV solutions are produced locally in medically emerging countries, the resulting return on initial
investments can be quite small. It is estimated that profitability would stand at only 50% of the total
production capacity.
The production costs that are incurred in developing IV solutions are 45% to 65% lower than the existing
market price for primary product lines. These estimates are based on U.S. cost figures. When the U.S.
system of calculation is used, both direct and indirect labor costs are the largest cost factors. However, in
developing nations, the labor cost is relatively low and the cost of IV solutions is much higher. Therefore,
the actual production cost can be estimated to be 60% to 90% lower than the market price of the product.
There is a very high demand for IV solutions. Therefore, even if a situation arises in which production is
more than the local demand, there are still excellent prospects of making national sales as well as sales
through exports.
The raw materials that are required to produce IV solutions are easy to procure as they are readily available
in local markets.

Global Market Analysis
The Intravenous Solutions market in North America is projected to garner the largest market of US$
XX.XX billion by 2020 and is anticipated to attain a value of US$ XX.XX billion by 2012. Europe is the second
largest market with a projected value of US$ XX.XX billion by 2020. Asia-Pacific is projected to have the
highest CAGR of XX.XX % through 2020.
Exhibit 4. Intravenous Solutions– Global Value Market Estimations & Predictions (2000-2005) by
Geographic Region for North America, Europe, Asia-Pacific and Rest of World in US$ Billion
Year /Region North America Europe Asia-Pacific Rest of World Total
2000 XX.XX XX.XX XX.XX XX.XX XX.XX
CAGR% XX.XX XX.XX XX.XX XX.XX XX.XX
2000 2001 2002 2003 2004 2005
US$ Billion
North America Europe Asia-Pacific Rest of World

Exhibit 5. Intravenous Solutions– Global Value Market Estimations & Predictions (2005-2020) by
Geographic Region for North America, Europe, Asia-Pacific and Rest of World in US$ Billion
2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020
US$ Billion
North America Europe Asia-Pacific Rest of World

Exhibit 6. Intravenous Solutions– Global Value Market Shares (2000, 2015 & 2020) by Geographic Region
for North America, Europe, Asia-Pacific and Rest of World in US$ Billion
IV SOLUTIONS – THE OUTLOOK
The United States is the largest market for Intravenous Solutions. Due to the cost advantage and rapid
increase in population, Asia-Pacific is the fastest growing (14.49% during 2005-2015) market for
Intravenous Solutions. Asia-Pacific and Rest of World are expected to gain market shares while the US may
lose market dominance by the end of the analysis period (2005-2020).
The alterations in the Government’s reimbursement policy have motivated hospitals to explore more
effective methods of administering drugs via the intravenous route. Several companies that supply
intravenous solutions have come up with innovations in their product lines. An industry leader in this field,
Baxter International, rapidly expanded its product line of pre-mixed frozen intravenous solutions. Abbot
Labs designed a system in which bottles of powdered drugs could be directly introduced into the bag of
intravenous fluid as required. The lids of these bottles are screwed open inside the sterile bags and the
drugs are subsequently introduced into the solution and mixed by shaking.
Key suppliers of nutritional intravenous solutions in international markets have also developed techniques
of pre-mixing nutrients that were formerly given separately to patients. Earlier pre-mixed intravenous
solutions were developed for the convenience they offered. Now the question of cost has been brought
into the equation. While such products appear quite simple, their development requires the use of some
advanced material such as new plastics that protect the solutions from heat, light, and contaminants.
The changes in Government policies have also facilitated the development of light and portable injection
devices. These are handy as patients can now receive intravenous treatments in doctor’s clinics or even in
their own homes. It is estimated that globally, about US$2 billion is spent on intravenous solutions
annually, of which almost 90% is used by hospitals. Despite this, it is estimated by industry sources that the
annual growth rate of the use of intravenous applications by hospitals stands at a mere 5-6%....

IV. PRODUCT TECHNOLOGY/RESEARCH
Intravenous Solutions
Parenteral nutrition refers to the delivery of nutrients into the patient’s body through a route other than
digestive system. Intravenous solution [IV] is considered as a kind of parenteral nutrition. IV means
intravenous or into a vein. It is a method of introducing the fluids, essential nutrients, and drugs into the
patient’s bloodstream. IV solutions are sterile nutrient solutions used for treating patients as a temporary
measure or for prolonged period. IV solution is introduced into the patient’s vein as drips via a tube and
passing through a needle inserted into the vein at the back of the hand, or inside the elbow, or some
suitable location in the body.
Composition
Basically, IV solution is sterilized water containing appropriate quantity of sodium [salt] or dextrose [sugar].
It is packed in bottle or thick plastic bag that can be hung from a stand placed on one side of the patient’s
bed. Additional mineral nutrients [potassium, calcium], vitamins, or drugs, as required, can be injected into
the bottle/bag with a needle. The basic sugar and salt solution can meet the calorie and electrolyte
requirements of the patient for a brief duration. But, when the patient has to be administered IV feeding
for a prolonged period, proteins and fats will also be included. The quantity of the nutrients is determined
based on the age, physiological condition, and special nutritional requirements of the patients.
Exhibit 7. Daily Electrolyte Requirement
Element Daily Requirement (meq/kg) for 70-KG Adult (meq/day)
Sodium 1.0-2.0 70-140
Potassium 0.5-1.0 35-70
Calcium 0.2-0.3 1.4-2.1
Magnesium 0.35-0.45 24.5-31.5
Chloride 1.0-2.0 70-140
Bicarbonate Acetate Use with chloride to balance cations and help pH Use with chloride to balance cations and help pH
Source : www.med.mun.ca
An IV solution is prepared according to the prescription given by the physician. The physician, pharmacist,
or nurse supervises the preparation of the IV solution adhering to strict aseptic techniques so that bacterial
contamination is avoided. The bag/bottle should contain the label pasted on it indicating the contents and
additives. The flow rate is also specified by the physician attending on the patient. The area of the patient’s
skin where the needle has to be inserted is wiped with a sanitizer. After inserting the needle into the vein, it
is securely fastened to prevent dislodging.

Exhibit 8. Electrolyte Contents for Common Fluids (mmol/litre)
Fluid/Content Na K Cl Mg Ca Lactate Osmolality
0.9%NaCI 154 0 154 0 0 0 308
0.18%saline 4%dextrose 30 0 30 0 0 0 284
0.45%saline 5%dextrose 77 0 77 0 0 0 406
Gelofusine 154 0 154 0 0 0 274
Hartmann’s 131 5 111 0 2 29 278
PlasmaLyte 148 140 5 98 1.2 0 Acetate 27 297
5%dextrose 0 0 0 0 0 190Kcal/I 278
Source : NHS
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 Identifying Key Growth Areas and Opportunities
 Understanding Geographic Relevance to Product
 Knowing Regional Market Sizes and Growth Opportunities and Restraints
 Keeping Tab on Emerging Technologies
 Equity Analysis
 Tapping New Markets
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