1. Curriculum Vitae
Personal data
 Name: Sara Silvia Roscioni
 Date and place of birth: 26/09/1980, Garbagnate Milanese, Italy
 Nationality: Italian
 Professional address Institute of Diabetes and Regeneration Research
HelmholtzZentrum München
Parkring 11 D-85748 Garching
Germany
Office Phone: +49-89-3187-2064
E-mail: sara.roscioni@helmholtz-muenchen.de
 Private address: Alfred-Neumann-Anger 15
81737 München, Germany
Private Phone: +49-172-5383116
Education
 October 1999 - March 2005: Master degree in Pharmaceutical Chemistry and Technology,
Faculty of Pharmacy, University of Milan (IT). (Final mark:
110/110)
 November 2005 – December 2005: Pharmacist certification, Milan (IT)
 October 2006 – December 2010: PhD-study at the Department of Molecular Pharmacology,
University of Groningen (NL)
 September 2011: Pharmacologist certification from the Dutch Society of
Pharmacology (NL)
Relevant Courses
 March 2007 Safe Microbiological Techniques, Groningen (NL)
 July 2007 Models and Technologies for Defining Phenotypes (NIH),
Winston-Salem, NC (USA)
 August 2007 Molecular Mechanisms in Signal Transduction and Cancer,
(FEBS/EMBO), Spetses (GR)

2.  September 2007 Laboratory Animal Science Course (ex. Art. 9 Experiments on
Animals Act), Groningen (NL)
 June 2008 Statistics Course, Groningen (NL)
 August 2011 Regression analysis course, Erasmus summer programme,
Rotterdam (NL)
 March 2012 Good Research Practices: GLP/GCP, Groningen (NL)
 March 2013 Introductory Clinical Research Organization course and exam
(BROK): Groningen (NL)
 March 2014 Training in animal experimentation and procedures at the
Hemholtz Zentrum München
 January 2015 Real Time PCR training course by Life Technologies
 July 2015 FACS training course by BD
Working experiences
 March 2005 – September 2005: Pharmacist trainee in Carimate, Como (IT)
 September 2005 – March 2006: Internship trainee at R&D Department of Organon Schering-
Plough, Oss (NL)
 March 2006 - September 2006: Pharmaceutical developer of extended release formulations at
R&D Department of Organon Schering-Plough, Oss (NL)
 October 2006 – December 2010: PhD candidate at the Department of Molecular Pharmacology,
Rijksuniversiteit Groningen (NL).
 March 2011-September 2013: Post-Doctoral fellow at the Department of Clinical Pharmacology,
University Medical Centre Groningen (NL)
 August 2011-September 2013: National research coordinator of a multicentre clinical
prospective study (PROVALID) in Groningen (NL)
 From September 2013: Post-Doctoral fellow at the Institute of Diabetes and
Regeneration Research, Helmholtz Zentrum München (DE)
Languages
 Italian Mother tongue
 English Fluent
 Dutch Fluent
 German Basic
Skills & Expertise
 Cellular and Molecular biology: Primary cell and tissue cultures, qRT-PCR, gel electrophoresis,
western blotting and northern blotting

3.  Biochemistry: Subcellular fractionation, cellular transfections, caveolae
isolation, lipoprotein separation, immunoprecipitation, ELISA,
pull-down assay, [3
H]-thymidine incorporation.
 Microscopy: Optical microscopy: phase contrast, bright field, confocal and
fluorescence microscopy
 Animal work: Airway smooth muscle strip isolation from guinea pig and cows,
pancreatic islet isolation from mice
 Clinical Pharmacology: Clinical study design
 Clinical study management: Clinical study submissions and notifications to the Local Ethic
Committee, doctors and patient recruitment, laboratory site
management, patient registration/data management,
communication with other team members, recruitment status
report and budget control
 Statistical (and drawing) packages SPSS, Stata, Prism, Sigma plot
 MS office applications Word, Excel, Powerpoint
 Student supervision and teaching Pharmacotherapy lessons for medical students, seminar/lecture
organization
Grants & Awards
 May 2005 Selected candidate in the “Leonardo Da Vinci Research Program
– Unipharma Graduates”, organized by the University of Rome
“La Sapienza” (IT)
 October 2008 Best oral presentation at the Figon Dutch Medicine Days 2008,
Lunteren (NL)
 March 2012 Dutch Asthma Foundation press release:
(http://research.longfonds.nl/database/epac-kan-centrale-rol-
spelen-in-regulatie-van-luchtwegfunctie)
 2008-2010 Travel grants from the Nederlandse Stichting voor
Farmacologische Wetenschappen, the Stichting Astma
Bestrijding and Groningen Graduate School of Medical Sciences
participate to the American Thoracic Society meetings in Toronto
(2008), San Diego (2009) and New Orleans (2010)
 December 2010 Financial support from the pharmaceutical companies Chiesi
Pharmaceuticals BV and Nycomed for the printing of the PhD
thesis
 June 2013 Co-applicant in the research grant: “Urinary proteomics to
predict and unravel mechanisms of renal and cardiovascular
disease in diabetic nephropathy”, funded by the European
Foundation for the study of Diabetes and by Boehringer
Ingelheim for a total amount of 260,000.00 euro

4. List of Publications
1. S.S.Roscioni, C.R.S.Elzinga, M.Schmidt. Naunyn-Schmiedeberg’s Arch Pharmacol (2008), 377: 345–357.*
2. R.Gosens, S.S.Roscioni, B.G.J.Dekkers, T.Pera, M. Schmidt, D.Schaafsma, J.Zaagsma, H.Meurs. Eur J
Pharmac (2008), 585: 385–397.
3. D.Schaafsma, S.S.Roscioni, M.Schmidt, H.Meurs. Cell Sign (008), 20: 1705–1714.
4. S.S.Roscioni, L.E.M.Kistemaker, M.H.Menzen, C.R.S.Elzinga, R.Gosens, A.J.Halayko, H.Meurs, M.Schmidt.
Respir Res (2009), 10:88.
5. M.Grandoch, S.S.Roscioni, M.Schmidt. Br J Pharmacol (2010), 159: 265-284.
6. S.S.Roscioni, H.Maarsingh, C.R.S.Elzinga, L.J.Schuur, M.H.Menzen, A.J.Halayko, H.Meurs, M.Schmidt. J Cell
Mol Med (2010), 15: 1151-63.
7. S.S.Roscioni, B.G.J.Dekkers, A.G.Prins, M.H.Menzen, H.Meurs, M.Schmidt, H.Maarsingh. Br J Pharmacol
(2010), 162: 193-209.
8. S.S.Roscioni, A.G.Prins, C.R.S.Elzinga, M.H.Menzen, B.G.J.Dekkers, A.J.Halayko, H.Meurs, H.Maarsingh,
M.Schmidt. Br J Pharmacol (2011), 164 (3): 958-69.
9. S.S.Roscioni & A.Oldenburger, E.Jansen, M.H.Menzen, A.J.Halayko, W.Timens, H.Meurs, H.Maarsingh,
M.Schmidt. PloS One (2012), 7(2):e31574.
10. S.S.Roscioni, H.J.Lambers Heerspink, D.deZeeuw. Nat Rev Nephrol (2011), 7: 427-8.
11. S.S.Roscioni, Y.Miao, D.deZeeuw, H.J.Lambers Heerspink. Diabetologia (2011), 54: 2965-67.
12. S.S.Roscioni, D.deZeeuw, S.J.L.Bakker, H.J.Lambers Heerspink. Nat Rev Nephrol (2012), 8(12):691-9.
13. S.S.Roscioni, D.de Zeeuw, M.E.Hellemons, H.Mischak, P.Zürbig, S.J.Bakker, R.T.Gansevoort, H.Reinhard,
F.Persson, M.Lajer, P.Rossing, H.J.Lambers Heerspink. Diabetologia (2013), 56(2):259-67.
14. M.J.Pena, H.J.Lambers Heerspink, M.E.Hellemons, T.Friedrich, G.Dallmann, M.Lajer, S.J.L.Bakker,
R.T.Gansevoort, P.Rossing, D.deZeeuw, S.S.Roscioni. Diabet Med (2014) Sep;31(9):1138-47.
15. S.S.Roscioni, H.J.Lambers Heerspink, D.deZeeuw. Kidney Int (2014) Jul;86(1):40-9.
16. S.S.Roscioni, H.J.Lambers Heerspink, D.deZeeuw. Nat Rev Nephrol (2014) Feb;10(2):77-87.
17. F.Schmitz, S.S.Roscioni, H.Lickert. Cell Metab (2015) Jul, 22(1): 58-59.
Personal description and future vision
Personally, I am a dynamic, ambitious and hard-working person with a wide and international pharmaceutical,
pharmacological and clinical background. I am flexible and enthusiast, a good team player but also a creative
leader. I possess optimal organizational, communicative and social skills. My drive and ambition have so far
helped me to achieve the most important targets in my scientific career and personal development.
As a pharmacist and pharmacologist my ultimate aim is to improve the patient quality of life and ameliorate
disease treatment by optimizing drug discovery and/or development. I believe that pharmaceutical/clinical
research offers the best platform to my scope due to its closer proximity to the patient setting and its relevant
impact on society.
I am interested in all therapeutic areas although my main expertise is in the fields of diabetes (with focus on
kidney and pancreas pathophysiology) and respirarory diseases.