Q3 2015 continues to demonstrate a trend towards digital health market maturity with an increase of investment dollars combined with larger, less frequent deals. ~ Benefits and insurance solutions remain at the top of the deals list for 2015, particularly as these businesses become more capital intensive. Genomics companies are also beginning to attract funding as the line between biotech and consumer health blurs. ~ While it’s no surprise that the Bay Area continues to bring in the most funding YTD, newer markets are also growing. With Chicago, Salt Lake City and South Florida each taking in over $125M, it’s clear that investment opportunities are everywhere. ~ Keeping with last year’s trend, seed and series A rounds comprise 64% of funding activity this quarter. Meanwhile, series B and C rounds are continuing to increase their share of the total 2015 deals, demonstrating the maturation of the market. ~ Investments relevant to the 50+ market have contributed to nearly half the funding in the last five years, with the number of deals as a percent of all digital health steadily increasing.

1. © 2015 StartUp Health, LLC
Published: April 1, 2015
TM
A StartUp Health InsightsTM Report
Published October 1, 2015 | Report data through September 30, 2015
Report is inclusive of seed, venture, corporate venture and private equity funding
Sign up to receive weekly funding insights at startuphealth.com
StartUp Health Insights
Digital Health Funding Rankings
Q3 2015 Report
INCLUDING 50+ MARKET FUNDING SPONSORED BY

2. Source: StartUp Health Insights | www.startuphealth.com/insights • Disclosure: Information, data and figures represent only publicly available data. © 2015 StartUp Health, LLC
Note: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding.
Overall 2015 funding year to date is slightly behind that of the same time last year. After a slower start to the year, Q3
funding increased and is on par with Q3 2014.
2
2015 Year to Date and Q3 Summary
1
Signs of a Maturing Market: The market continues to see a steady increase in mid stage (Series B and C) deals with 31%, as
early stage deals hold strong with 64% of this year’s volume. With the continued growth of Series A rounds, we predict that
follow-on rounds will increase in pace as entrepreneurs are able to prove significant traction to gain investors’ confidence.
2
A Diverse Investor Landscape: A few years ago, it was incredibly rare to see traditional tech VCs and corporate VCs
investing in healthcare. Today, both of these groups are integral in the market. This quarter, however, saw the advent of a
non-venture investment firm and a holding company entering the ranks of top investors for the year.
3
Personalized Medicine Gains Traction: Genomics and diagnostics as subsectors make up a large portion of both early and
late stage deals. As cancer paves the way for personalized DNA-based therapies, we expect to see opportunities focused
on newborns, immunology and infectious disease begin to gain steam.
4
Wellness and Patient / Consumer Experience Sectors Are on Top: Although big data still continues to garner a lot
of interest from investors, wellness solutions and patient / consumer experience companies have picked up
momentum.
5
Global Innovation: More than 7,700 startups around the world are developing solutions in digital health, based on StartUp
Health Insights data. Innovation continues to thrive as borders between technologies, talent and nations blur to spur
real change in medical systems at home and abroad.
DEALS & FUNDING INVESTORS 50+ MARKET

3. Source: StartUp Health Insights | www.startuphealth.com/insights • Disclosure: Information, data and figures represent only publicly available data. © 2015 StartUp Health, LLC
Note: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding.
151
279
468
616
559
312
3
Digital Health Funding Snapshot Year Over Year
Funding($B)
$2
$4
$6
$8
2010 2011 2012 2013 2014 2015 YTD
Q1 Q2 Q3 Q4
$1.2B
$2.0B
$2.5B
$2.9B
$6.9B
$1.89B
$646M
$1.85B
$821M
$681M
$265M
Q3 2015 continues to demonstrate a trend towards digital health market maturity with an increase of investment dollars
combined with larger, less frequent deals.
Deal Count
$4.7B
DEALS & FUNDING INVESTORS 50+ MARKET

4. Source: StartUp Health Insights | www.startuphealth.com/insights • Disclosure: Information, data and figures represent only publicly available data. © 2015 StartUp Health, LLC
Note: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding.
The Top 10 Most Active Sectors of 2015 YTD
DEALS & FUNDING INVESTORS 50+ MARKET
4
Sector $ Invested # of Deals Notable Deals
1 Patient / Consumer Experience $1.1B 62
• Guahao
• Omada Health
2 Wellness $876M 32
• Headspace
• KFit
3 Personalized Health / Quantified Self $461M 23
• Helix
• 23andMe
4 E-Commerce $409M 17
• PokitDoc
• Practo Technologies
5 Workflows $406M 38
• Care at Hand
• Kyruus
6 Big Data / Analytics $395M 30
• LaunchPoint
• Metabiota
7 Medical Devices $329M 34
• InfoBionic
• Virtual Incision
8 Clinical Decision Support $196M 18
• lifeIMAGE
• MedCPU
9 Population Health $185M 13
• Grand Rounds
• Advance Health
10 Research $90M 8
• Codagenix
• Mousera
*
* Refer to the methodologies for which subsectors make up the broader sectors listed here
The leading sector of 2014, big data / analytics, dropped in funding activity for 2015, with much of the focus around patient
experience, wellness and other preventative solutions.

5. Source: StartUp Health Insights | www.startuphealth.com/insights • Disclosure: Information, data and figures represent only publicly available data. © 2015 StartUp Health, LLC
Note: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding.
Company $ Invested Subsector Notable Investment
1 $500M Benefits
2 $394M Navigating the Healthcare System
3 $145M Insurance
4 $130M Navigating the Healthcare System
5 $108M Genomics
6 $100M Personalized Health Undisclosed
6 $100M Insurance
8 $90M Navigating the Healthcare System
9 $79M Genomics Undisclosed
10 $70M Big Data / Analytics
10 $70M Benefits
Benefits and insurance solutions remain at the top of the list, particularly as the businesses become more capital intensive.
Genomics companies are beginning to attract funding as the line between biotech and consumer health continues to blur.
The Top 10 Largest Deals of 2015 YTD
5
DEALS & FUNDING INVESTORS 50+ MARKET
*Clover Health deal is a combination of equity and debt.

6. Source: StartUp Health Insights | www.startuphealth.com/insights • Disclosure: Information, data and figures represent only publicly available data. © 2015 StartUp Health, LLC
Note: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding.
Company $ Invested Subsector Notable Investor
1 $9.6M Sensors
2 $9.5M Navigating the Healthcare System Angels
2 $9.5M Mental Health
4 $9.4M Diagnostics
5 $9.1M Pharmaceuticals
6 $9.0M Corporate Wellness
7 $8.7M Wearables
8 $8.6M Navigating the Healthcare System
9 $8.4M Diagnostics
10 $8.0M Diagnostics Undisclosed
10 $8.0M Health IT
10 $8.0M Social Engagement
10 $8.0M Big Data / Analytics
Mirroring the broader digital health market, deals under $10M show the rise in popularity of funding of patient / consumer
experience startups.
The Top 10 Deals Under $10M of 2015 YTD
DEALS & FUNDING INVESTORS 50+ MARKET
6

7. Source: StartUp Health Insights | www.startuphealth.com/insights • Disclosure: Information, data and figures represent only publicly available data. © 2015 StartUp Health, LLC
Note: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding.
The Top 10 Most Active US Metro Areas of 2015 YTD
DEALS & FUNDING INVESTORS 50+ MARKET
Metro Area
1 SF Bay Area
2 NYC Metro Area
3 Boston
4 South Florida
5 Los Angeles
6 Chicago
7 Salt Lake City
8 San Diego
9 DC Metro Area
10 Seattle
While it’s no surprise that the Bay Area continues to bring the most funding YTD, emerging regions continue to grow. With
Chicago, Salt Lake City and South Florida each taking in over $125M, it’s clear that investment opportunities are everywhere.
7
$90M
$508M
$318M
$134M
$1.6B
SF Bay Area
San Diego
Salt Lake City
New York City
Boston
$148M
$248M
South Florida
$87M
DC Metro Area
(12 Deals)
(4 Deals)
(81 Deals)
(8 Deals)
(5 Deals)
(14 Deals)
(37 Deals)
(28 Deals)
Seattle
$80M (8 Deals)
Los Angeles
$245M
(12 Deals)
Chicago

8. Source: StartUp Health Insights | www.startuphealth.com/insights • Disclosure: Information, data and figures represent only publicly available data. © 2015 StartUp Health, LLC
Note: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding.
Keeping with last year’s trend, Seed and Series A rounds comprised 64% of funding activity in 2015 YTD. Meanwhile, Series
B and C rounds are continuing to increase their share of total 2015 deals, demonstrating the maturation of the market.
8
Deal Activity by Stage for 2015 YTD
2010
2011
2012
2013
2014
2015
YTD
0% 25% 50% 75% 100%
Seed Series A Series B Series C Series D Series E Series F + G
DEALS & FUNDING INVESTORS 50+ MARKET
29% 35% 11%20% 2%

9. Source: StartUp Health Insights | www.startuphealth.com/insights • Disclosure: Information, data and figures represent only publicly available data. © 2015 StartUp Health, LLC
Note: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding.
9
Funding Deep Dive: Funding of the Top 3 Specialties 2015 YTD
DEALS & FUNDING INVESTORS 50+ MARKET
While the total dollars in oncology, cardiology and diabetes has decreased since 2014, funding in these chronic diseases
continues to be the leading areas of interest for investors. The biggest challenge for entrepreneurs will be differentiating
themselves in the market, as investors learn more about the landscape.
$0.3B
$0.00B
$0.25B
$0.50B
$0.75B
$1.00B
2010 2011 2012 2013 2014 2015 YTD
Oncology Cardiology Diabetes

10. Source: StartUp Health Insights | www.startuphealth.com/insights • Disclosure: Information, data and figures represent only publicly available data. © 2015 StartUp Health, LLC
Note: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding.
$1M
$2M
$3M
$4M
$5M
$6M
$7M
2010 2011 2012 2013 2014 2015 YTD
$4.5 $4.6
$3.4
$4.0
$5.5
$6.0
$1.0
$0.8 $0.6 $0.8
$1.3
$1.7
Seed Round Series A
10
Funding Deep Dive: Early Stage Median Investment Landscape
DEALS & FUNDING INVESTORS 50+ MARKET
The abundance of capital for innovation in digital health, coupled with investors wanting to see more traction at the
Series A round stage, have contributed to Seed round median size growing faster than Series A deals.
9%
36%
38%
80%

11. Source: StartUp Health Insights | www.startuphealth.com/insights • Disclosure: Information, data and figures represent only publicly available data. © 2015 StartUp Health, LLC
Note: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding.
The Top 12 Most Active Venture Investors of 2015 YTD
DEALS & FUNDING INVESTORS 50+ MARKET
11
Firm 2015 YTD Deals 2014 Deals Stage
Early Mid Late
1 9 7
2 8 10
3 7 1
3 7 6
3 7 7
3 7 3
3 7 7
3 7 2
9 6 4
9 6 4
9 6 12
12 5 7
12 5 8
12 5 3
Investors outside of traditional venture firms are placing significant bets within digital health with corporate VCs, an
investment firm and a holdings company making our top 12 most active list YTD.

12. Source: StartUp Health Insights | www.startuphealth.com/insights • Disclosure: Information, data and figures represent only publicly available data. © 2015 StartUp Health, LLC
Note: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding.
50+ Market Funding Snapshot for 2015 YTD
186
DEALS & FUNDING INVESTORS 50+ MARKET
Funding($B)
$0.8B
$1.6B
$2.4B
$3.2B
$4.0B
Deals
70
140
210
280
2010 2011 2012 2013 2014 2015 YTD
Deals Funding
$1.7B$3.5B$1.6B$1.5B$1.3B$0.7B
152
267
254
212
148
7373
148
212
254
267
152
50+ market funding in Q3 2015 gained momentum, with a 50% increase over the funding averages of Q1 and Q2 2015.
$1.7B
12

13. Source: StartUp Health Insights | www.startuphealth.com/insights • Disclosure: Information, data and figures represent only publicly available data. © 2015 StartUp Health, LLC
Note: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding.
20%
40%
60%
80%
100%
56%
58% 58%
49% 50% 49%50% 51% 50%
44%
50%
54%
% of Total Deal Count % of Total Funding
50+ Market Investments as % of Total Investments in Digital Health
DEALS & FUNDING INVESTORS 50+ MARKET
47%
45%
2010 2012 2013 20142011 2015 YTD
26%
Investments relevant to the 50+ market have contributed to nearly half the funding in the last five years, with the
number of deals as a percent of all digital health hovering around 50%.
13
50%
50%

14. Source: StartUp Health Insights | www.startuphealth.com/insights • Disclosure: Information, data and figures represent only publicly available data. © 2015 StartUp Health, LLC
Note: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding.
Investors around the globe are funding companies that address the needs of 50+ consumers at all stages, with notable
involvement from corporate and strategic investors.
The Top 50+ Market Venture Investors of 2015 YTD
DEALS & FUNDING INVESTORS 50+ MARKET
14
Firm 2015 YTD Deals Notable Deal Stage
Early Mid Late
1 7 HeartFlow
2 6 Doctor on Demand
3 5 Caremerge
3 5 Stride Health
3 5 Noom
6 4 PillPack
6 4 Wildflower Health
6 4 Accolade
6 4 Stride Health
6 4 Omada Health

15. Source: StartUp Health Insights | www.startuphealth.com/insights • Disclosure: Information, data and figures represent only publicly available data. © 2015 StartUp Health, LLC
Note: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding.
General:
• StartUp Health has a broad view of digital health and believe that the current trend is a cross-pollination of technology and data with all aspects of health and healthcare. StartUp Health
Insights tracks companies that enable health, wellness and the delivery of care through data / analytics, sensors, mobile, internet-of-things, 3D printing and genomics and personalized
medicine.
• Q2 & Q3 2015 brought with it an extensive database quality assessment. A new, evolving system was implemented allowing StartUp Health to track innovation with enhanced granularity.
Additionally, gaps in funding data were researched and added into our database enabling us to identify fundings previously unaccounted for in past reports.
Sectors:
• StartUp Health defines “sector” as one of the below 13 major markets that make up the bulk of funding in digital health. Each sector, is also broken into subsectors, which can crossover
among sectors. A list of the sectors and examples of subsectors are below:
• Big Data / Analytics: Pharma, Predictive, Research
• Clinical Decision Support: EMR, Physician Tools, Point of Care
• E-commerce: Marketplaces, Media, Supply Chain
• Education / Training: Gamification, Medical Device, Mobile Apps
• EMR: Fraud, Patient Portals, Workflows / Interoperability
• Medical Devices: Diagnostics, Medical Imaging, Sensors
• Patient / Consumer Experience: Medication Adherence, Navigating the Healthcare System, Telemedicine
• Personalized Health / Quantified Self: Genomics, Personalized Medicine, Wearables
• Population Health: Big Data / Analytics, EMR, Patient Engagement
• Research: Clinical Trials, Genomics, Pharma
• Wellness: Benefits, Mental Health, Nutrition
• Workflows: Scheduling, Care Coordination, Billing
• 50 Plus: Behavioral Health, Medication Adherence, Vital Signs Monitoring
• Investments in subsectors are not mutually exclusive as deals are tagged with multiple subsectors.
Stage of funding:
• StartUp Health Insights records only publicly available data on cash for equity investments as the cash is actually received by the company. StartUp Health Insights is inclusive of all
accelerator, seed, venture, corporate venture and private equity funding. Funding from accelerators is not included in these quarterly reports.
• Early stage: The company has raised a Seed or Series A round
• Mid stage: The company has raised a Series B or Series C round
• Late stage: The company has raised a Series D or other growth equity round
• StartUp Health also tracks incubator rounds and other financings into privately-held entities (e.g. “unnamed” venture rounds, strategic investments, growth equity and private equity).
• In tabulating deal activity by stage we excluded rounds not clearly associated with a specific stage.
Sources:
• Funding data is from StartUp Health Insights, the most comprehensive funding database for digital health, and managed by the StartUp Health team. Information, data and figures represent
only publicly available data, unless otherwise confirmed by the company receiving capital or a participating investor.
• Data for acquisitions slide was provided by a range of sources including StartUp Health Insights, CrunchBase, AngelList and news reports.
• StartUp Health works to ensure that the information contained in the StartUp Health Insights Report has been obtained from reliable sources. However, StartUp Health cannot warrant the
ultimate validity of the data obtained in this manner. All data is subject to verification with the venture capital firms and/or the investee companies. Results are updated periodically.
Therefore, all data is subject to change at any time. If you find an error please let us know so we can correct it.
This report is provided for informational purposes and was prepared in good faith on the basis of public information available at the time of publication without independent verification. StartUp
Health does not guarantee or warrant the reliability or completeness of the data nor its usefulness in achieving any particular purposes. StartUp Health shall not be liable for any loss, damage,
cost or expense incurred by reason of any persons use or reliance on this report. This report is a proprietary aggregation of publicly available data and shall not be forwarded or reproduced
without the written consent of StartUp Health.
15
Our Methodologies

16. Source: StartUp Health Insights | www.startuphealth.com/insights • Disclosure: Information, data and figures represent only publicly available data. © 2015 StartUp Health, LLC
Note: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding.
StartUp Health is a global health innovation company. The StartUp Health Platform, including its Academy, Network and
Innovation Fund, is empowering a global network of entrepreneurs and innovators to transform healthcare. With over 100
companies, StartUp Health has the world’s largest portfolio of digital health companies from 11 countries and 50 cities.
StartUp Health was founded in 2011 by Steven Krein and Unity Stoakes and is chaired by former Time Warner CEO, Jerry
Levin. StartUp Health’s notable strategic partners and investors include AARP, AON, Aurora Health Care, California
Healthcare Foundation, Steve Case, Cleveland Clinic, Conifer Health Solutions, Mark Cuban, Esther Dyson, Roger
Ehrenberg, Brad Feld, GE Ventures, Kaiser Permanente Ventures, Robert Wood Johnson Foundation, SeventySix Capital
and Stericycle.
Learn more at startuphealth.com and follow @startuphealth. For press inquiries, email press@startuphealth.com
16
About StartUp Health

17. StartUp Health Companies