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Novel diagnostic procedure
Facebook: can it be a diagnostic tool for neurologists?
Manoj K Mittal,1 Jeff A Sloan,2 Alejandro A Rabinstein1
1
Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
2
Department of Biostatistics and Oncology, Mayo Clinic, Rochester, Minnesota, USA

Correspondence to Manoj Kumar Mittal, drmanojkumarmittal@gmail.com


Summary
A 56-year-old woman presented with acute ischaemic stroke with NIHSS 13. She had right eye ptosis and miosis. She and her husband
were not sure if her facial features were different than usual. With her consent, we compared her face with her pictures on Facebook. In
the absence of any ptosis or miosis in her pictures, she was diagnosed with acute Horner syndrome. Facebook may be a useful tool for
the neurologists to define the timing of facial neurological signs.



BACKGROUND                                                                         324 mg and clopidogrel 300 mg. She was transferred to
Facebook is a social media website with more than 845                              neurological intensive care unit for closer monitoring.
million monthly active users. It has been increasingly                                In the intensive care unit, she was noted to have right
used in healthcare for patient education, research enrol-                          ptosis and mild right miosis with pupil 0.6 mm smaller
ment, patient follow-up, behavioural research, and chan-                           than the left side (figure 1D). She and her husband were
ging health policies.1–4 Most of the residents and fellows                         not sure if her facial features were different than usual. We
have a Facebook profile.5                                                           checked her driver’s licence but her picture was not clear
  Literature review did not show any published cases                               enough to make a comparison. She had no other pictures
where Facebook was used as a diagnostic tool in neur-                              with her. We asked her if she had pictures on her Facebook
ology. We describe here a patient with acute neurological                          profile to which she responded affirmatively. As our patient
emergency where Facebook played a significant role in her                           was competent to give consent, we asked for her verbal
diagnosis.                                                                         permission to compare her pictures on Facebook with her
                                                                                   present facial features to clarify if the eyelid droop was
                                                                                   new or old. She gave us her verbal consent and showed us
CASE PRESENTATION
                                                                                   her Facebook profile pictures. After looking through eight
A 56-year-old previously healthy, non-smoker female had
                                                                                   profile pictures we found a recent close-up photograph
sudden onset of left-sided hemiparesis, left facial droop,
                                                                                   showing no ptosis. Miosis was hard to access as the pupil
and dysarthria. She was taken to a local emergency room.
                                                                                   difference was only 0.6 mm at present. Ptosis was thought
Computed axial tomography (CAT) scan of the head did
                                                                                   to be new in onset. On further questioning, she admitted
not show any acute bleed but did show right hyperdense
                                                                                   visiting a chiropractor 2 days ago for neck stiffness for
middle cerebral artery (MCA) (figure 1A). Two hours after
                                                                                   which she underwent spinal manipulation. A diagnosis of
acute stroke onset, 50 mg of intravenous tenecteplase was
                                                                                   right ICA dissection was established. Her laboratory
given and the patient was transferred to Saint Mary hos-
                                                                                   testing showed haemoglobin 13.4 g/dl (reference range
pital via helicopter.
                                                                                   [RR]: 12–15.5 g/dl), International normalised ratio 1.0
  At arrival, NIHSS was 13 for slurred speech, right gaze
                                                                                   (RR: 0.8–1.2), haemoglobin A1c 5.0% (RR: 4.0–6.0%) and
deviation, left moderate facial droop, complete left hemi-
                                                                                   low-density-lipoprotein 72 mg/dl (RR: <100 mg/dl). Her
paresis and left haemineglect.
                                                                                   extinction improved the next day. Repeat CAT scan head at
                                                                                   24 h showed hypodensity in the insular cortex and lenti-
INVESTIGATIONS                                                                     form nucleus.
Cerebral angiogram showed 95% stenosis of right internal
carotid artery (ICA) at its origin along with right MCA                            TREATMENT
occlusion (figure 1B). Angioplasty resulted in good recana-                         She was started on aspirin 81 mg daily, clopidogrel 75 mg
lisation, thrombolysis in cerebral ischaemia (TICI) 2b6                            daily, and simvastatin 20 mg daily.
across the MCA with persistent occlusion of posterior M2
MCA branch. Left carotid injection demonstrated cross fill                          OUTCOME AND FOLLOW-UP
from left to right with excellent left meningeal collaterals                       She was discharged home after 5 days of hospitalisation
to fill the non-perfused M2 territory. Repeat angiogram                             with NIHSS of two and modified Rankin score of two.
showed restenosis of ICA origin, following which an
Enterprise carotid stent was placed with TICI 2c flow in                            DISCUSSION
ICA (figure 1C). Patient’s NIHSS was three (left mild                               Facebook helped us to reach to the correct aetiological diag-
facial droop, mild dysmetria, and mild extinction) imme-                           nosis of acute ICA dissection in our patient. ICA dissection
diately postprocedure. Patient was loaded with aspirin                             causes Horner syndrome via damage to the third-order

BMJ Case Reports 2012; doi:10.1136/bcr-2012-006426                                                                                         1 of 3
Figure 1 Non-contrasted CT head showing right hyperdense middle cerebral artery (A). Cerebral angiogram showing 95% right internal
carotid artery origin stenosis and occlusion of right middle cerebral artery (B). Postcarotid stenting cerebral angiogram showing
recanalisation of right internal carotid artery and middle cerebral artery (C). Right eyelid ptosis and mild miosis consistent with Horner
syndrome (D).


sympathetic neurons.7 Traditionally, neurologists used                    dangerous source of information. Facebook may be a
patients’ driving licence or previous photographs to                      useful diagnostic tool in patients with Horner syndrome
compare their picture to see if the Horner syndrome is new                and other neurological disorders like Bell’s palsy, inter-
or pre-existing.8 There are several limitations to this                   nuclear ophthalmoplegia, strabismus, Grave’s ophthalmo-
approach, mainly poor quality of photograph, patient may                  pathy and myasthenia gravis.
have closed their eyes due to the flash making evaluation
difficult, the photograph may be too old, dependency on a
single photograph, fading of colours and outlines of photo-                 Learning points
graph with time, and unavailability of driver’s licence of
paper photograph at the time of neurological emergency.                    ▸ Facebook and other social media are increasingly being
Facebook offsets all these limitations of paper photograph                   used by patients, and physicians.
by providing high-quality, recent, multiple digital, and                   ▸ Recent pictures are available immediately using social
close-up shots. Facebook can be easily accessed in a                         media.
patient’s room via a Smartphone, computer, Ipad and                        ▸ Facebook may be a useful diagnostic tool in patients
other android tablet, Iphone, or laptop.                                     with Horner syndrome and other neurological disorders
   Our patient’s Facebook profile helped us to compare her                    such as Bell’s palsy, internuclear ophthalmoplegia,
current ptosis with her previous pictures at the bedside.                    strabismus, Grave’s ophthalmopathy and myasthenia
This vital information helped us to find out the spinal                       gravis.
manipulation done 48 h ago which might have led to ICA
dissection, resulting in high-grade symptomatic stenosis
and acute ischaemic stroke in our patient.
   Facebook use has been increasing in healthcare over the                Competing interests None.
last few years. There are several legal and ethical chal-                 Patient consent Obtained.
lenges in using social media such as Facebook use in
healthcare for accessing patient information.9 Social
media was originally designed for social communications
between family and friends. Use of social media in medi-                  REFERENCES
                                                                           1. Fenner Y, Garland SM, Moore EE, et al. Web-based recruiting for health
cine is new and the ethical issues related to an individual’s
                                                                              research using a social networking site: an exploratory study. J Med Internet
privacy have not been delineated so far. Access to patient’s                  Res 2012;14:e20.
information on social media via verbal or written consent                  2. Moreno MA, Jelenchick LA, Egan KG, et al. Feeling bad on Facebook:
may be appropriate if that information is used for the                        depression disclosures by college students on a social networking site.
patient’s medical care. All physicians, residents and stu-                    Depress Anxiety 2011;28:447–55.
                                                                           3. Howell WL. Patient education. Facebook isn’t just for status updates or
dents should be aware of patients’ privacy while accessing                    playing games anymore. Hosp Health Netw 2011;85:13.
their information via social media. This information                       4. Abdul SS, Lin CW, Scholl J, et al. Facebook use leads to health-care reform
should only be used for the patient’s medical care free of                    in Taiwan. Lancet 2011;377:2083–4.
any judgment about the patient as sometimes the pic-                       5. Moubarak G, Guiot A, Benhamou Y, et al. Facebook activity of residents and
                                                                              fellows and its impact on the doctor-patient relationship. J Med Ethics
tures or the information provided on social media may be
                                                                              2011;37:101–4.
inappropriate in the boundary of the patient–physician                     6. Noser EA, Shaltoni HM, Hall CE, et al. Aggressive mechanical clot
relationship. Although information provided on Facebook                       disruption. Stroke 2005;36:292–6.
is public, patient’s informed consent must be taken prior                  7. Ryan FH, Kline LB, Gomez C. Congenital Horner’s syndrome resulting from
to the use of Facebook or any other social media. Timely                      agenesis of the internal carotid artery. Ophthalmology 2000;107:185–8.
                                                                           8. Blacker DJ, Wijdicks EF. A ripping roller coaster ride. Neurology
research is much needed in this area to explore these                         2003;61:1255.
issues and guidelines are need to direct physicians how to                 9. Cain J, Fink JL. Legal and ethical issues regarding social media and
appropriately use this new exciting yet potentially                           pharmacy education. Am J Pharm Educ 2010;74:184.


2 of 3                                                                                           BMJ Case Reports 2012; doi:10.1136/bcr-2012-006426
This pdf has been created automatically from the final edited text and images.
  Copyright 2012 BMJ Publishing Group. All rights reserved. For permission to reuse any of this content visit
  http://group.bmj.com/group/rights-licensing/permissions.
  BMJ Case Report Fellows may re-use this article for personal use and teaching without any further permission.

  Please cite this article as follows (you will need to access the article online to obtain the date of publication).
  Mittal MK, Sloan JA, Rabinstein AA. Facebook: can it be a diagnostic tool for neurologists?. BMJ Case Reports 2012;10.1136/bcr-2012-006426,
  Published XXX
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BMJ Case Reports 2012; doi:10.1136/bcr-2012-006426                                                                                              3 of 3

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BMJ Case Reports - Facebook and Diagnosis - 2012

  • 1. Novel diagnostic procedure Facebook: can it be a diagnostic tool for neurologists? Manoj K Mittal,1 Jeff A Sloan,2 Alejandro A Rabinstein1 1 Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA 2 Department of Biostatistics and Oncology, Mayo Clinic, Rochester, Minnesota, USA Correspondence to Manoj Kumar Mittal, drmanojkumarmittal@gmail.com Summary A 56-year-old woman presented with acute ischaemic stroke with NIHSS 13. She had right eye ptosis and miosis. She and her husband were not sure if her facial features were different than usual. With her consent, we compared her face with her pictures on Facebook. In the absence of any ptosis or miosis in her pictures, she was diagnosed with acute Horner syndrome. Facebook may be a useful tool for the neurologists to define the timing of facial neurological signs. BACKGROUND 324 mg and clopidogrel 300 mg. She was transferred to Facebook is a social media website with more than 845 neurological intensive care unit for closer monitoring. million monthly active users. It has been increasingly In the intensive care unit, she was noted to have right used in healthcare for patient education, research enrol- ptosis and mild right miosis with pupil 0.6 mm smaller ment, patient follow-up, behavioural research, and chan- than the left side (figure 1D). She and her husband were ging health policies.1–4 Most of the residents and fellows not sure if her facial features were different than usual. We have a Facebook profile.5 checked her driver’s licence but her picture was not clear Literature review did not show any published cases enough to make a comparison. She had no other pictures where Facebook was used as a diagnostic tool in neur- with her. We asked her if she had pictures on her Facebook ology. We describe here a patient with acute neurological profile to which she responded affirmatively. As our patient emergency where Facebook played a significant role in her was competent to give consent, we asked for her verbal diagnosis. permission to compare her pictures on Facebook with her present facial features to clarify if the eyelid droop was new or old. She gave us her verbal consent and showed us CASE PRESENTATION her Facebook profile pictures. After looking through eight A 56-year-old previously healthy, non-smoker female had profile pictures we found a recent close-up photograph sudden onset of left-sided hemiparesis, left facial droop, showing no ptosis. Miosis was hard to access as the pupil and dysarthria. She was taken to a local emergency room. difference was only 0.6 mm at present. Ptosis was thought Computed axial tomography (CAT) scan of the head did to be new in onset. On further questioning, she admitted not show any acute bleed but did show right hyperdense visiting a chiropractor 2 days ago for neck stiffness for middle cerebral artery (MCA) (figure 1A). Two hours after which she underwent spinal manipulation. A diagnosis of acute stroke onset, 50 mg of intravenous tenecteplase was right ICA dissection was established. Her laboratory given and the patient was transferred to Saint Mary hos- testing showed haemoglobin 13.4 g/dl (reference range pital via helicopter. [RR]: 12–15.5 g/dl), International normalised ratio 1.0 At arrival, NIHSS was 13 for slurred speech, right gaze (RR: 0.8–1.2), haemoglobin A1c 5.0% (RR: 4.0–6.0%) and deviation, left moderate facial droop, complete left hemi- low-density-lipoprotein 72 mg/dl (RR: <100 mg/dl). Her paresis and left haemineglect. extinction improved the next day. Repeat CAT scan head at 24 h showed hypodensity in the insular cortex and lenti- INVESTIGATIONS form nucleus. Cerebral angiogram showed 95% stenosis of right internal carotid artery (ICA) at its origin along with right MCA TREATMENT occlusion (figure 1B). Angioplasty resulted in good recana- She was started on aspirin 81 mg daily, clopidogrel 75 mg lisation, thrombolysis in cerebral ischaemia (TICI) 2b6 daily, and simvastatin 20 mg daily. across the MCA with persistent occlusion of posterior M2 MCA branch. Left carotid injection demonstrated cross fill OUTCOME AND FOLLOW-UP from left to right with excellent left meningeal collaterals She was discharged home after 5 days of hospitalisation to fill the non-perfused M2 territory. Repeat angiogram with NIHSS of two and modified Rankin score of two. showed restenosis of ICA origin, following which an Enterprise carotid stent was placed with TICI 2c flow in DISCUSSION ICA (figure 1C). Patient’s NIHSS was three (left mild Facebook helped us to reach to the correct aetiological diag- facial droop, mild dysmetria, and mild extinction) imme- nosis of acute ICA dissection in our patient. ICA dissection diately postprocedure. Patient was loaded with aspirin causes Horner syndrome via damage to the third-order BMJ Case Reports 2012; doi:10.1136/bcr-2012-006426 1 of 3
  • 2. Figure 1 Non-contrasted CT head showing right hyperdense middle cerebral artery (A). Cerebral angiogram showing 95% right internal carotid artery origin stenosis and occlusion of right middle cerebral artery (B). Postcarotid stenting cerebral angiogram showing recanalisation of right internal carotid artery and middle cerebral artery (C). Right eyelid ptosis and mild miosis consistent with Horner syndrome (D). sympathetic neurons.7 Traditionally, neurologists used dangerous source of information. Facebook may be a patients’ driving licence or previous photographs to useful diagnostic tool in patients with Horner syndrome compare their picture to see if the Horner syndrome is new and other neurological disorders like Bell’s palsy, inter- or pre-existing.8 There are several limitations to this nuclear ophthalmoplegia, strabismus, Grave’s ophthalmo- approach, mainly poor quality of photograph, patient may pathy and myasthenia gravis. have closed their eyes due to the flash making evaluation difficult, the photograph may be too old, dependency on a single photograph, fading of colours and outlines of photo- Learning points graph with time, and unavailability of driver’s licence of paper photograph at the time of neurological emergency. ▸ Facebook and other social media are increasingly being Facebook offsets all these limitations of paper photograph used by patients, and physicians. by providing high-quality, recent, multiple digital, and ▸ Recent pictures are available immediately using social close-up shots. Facebook can be easily accessed in a media. patient’s room via a Smartphone, computer, Ipad and ▸ Facebook may be a useful diagnostic tool in patients other android tablet, Iphone, or laptop. with Horner syndrome and other neurological disorders Our patient’s Facebook profile helped us to compare her such as Bell’s palsy, internuclear ophthalmoplegia, current ptosis with her previous pictures at the bedside. strabismus, Grave’s ophthalmopathy and myasthenia This vital information helped us to find out the spinal gravis. manipulation done 48 h ago which might have led to ICA dissection, resulting in high-grade symptomatic stenosis and acute ischaemic stroke in our patient. Facebook use has been increasing in healthcare over the Competing interests None. last few years. There are several legal and ethical chal- Patient consent Obtained. lenges in using social media such as Facebook use in healthcare for accessing patient information.9 Social media was originally designed for social communications between family and friends. Use of social media in medi- REFERENCES 1. Fenner Y, Garland SM, Moore EE, et al. Web-based recruiting for health cine is new and the ethical issues related to an individual’s research using a social networking site: an exploratory study. J Med Internet privacy have not been delineated so far. Access to patient’s Res 2012;14:e20. information on social media via verbal or written consent 2. Moreno MA, Jelenchick LA, Egan KG, et al. Feeling bad on Facebook: may be appropriate if that information is used for the depression disclosures by college students on a social networking site. patient’s medical care. All physicians, residents and stu- Depress Anxiety 2011;28:447–55. 3. Howell WL. Patient education. Facebook isn’t just for status updates or dents should be aware of patients’ privacy while accessing playing games anymore. Hosp Health Netw 2011;85:13. their information via social media. This information 4. Abdul SS, Lin CW, Scholl J, et al. Facebook use leads to health-care reform should only be used for the patient’s medical care free of in Taiwan. Lancet 2011;377:2083–4. any judgment about the patient as sometimes the pic- 5. Moubarak G, Guiot A, Benhamou Y, et al. Facebook activity of residents and fellows and its impact on the doctor-patient relationship. J Med Ethics tures or the information provided on social media may be 2011;37:101–4. inappropriate in the boundary of the patient–physician 6. Noser EA, Shaltoni HM, Hall CE, et al. Aggressive mechanical clot relationship. Although information provided on Facebook disruption. Stroke 2005;36:292–6. is public, patient’s informed consent must be taken prior 7. Ryan FH, Kline LB, Gomez C. Congenital Horner’s syndrome resulting from to the use of Facebook or any other social media. Timely agenesis of the internal carotid artery. Ophthalmology 2000;107:185–8. 8. Blacker DJ, Wijdicks EF. A ripping roller coaster ride. Neurology research is much needed in this area to explore these 2003;61:1255. issues and guidelines are need to direct physicians how to 9. Cain J, Fink JL. Legal and ethical issues regarding social media and appropriately use this new exciting yet potentially pharmacy education. Am J Pharm Educ 2010;74:184. 2 of 3 BMJ Case Reports 2012; doi:10.1136/bcr-2012-006426
  • 3. This pdf has been created automatically from the final edited text and images. Copyright 2012 BMJ Publishing Group. All rights reserved. For permission to reuse any of this content visit http://group.bmj.com/group/rights-licensing/permissions. BMJ Case Report Fellows may re-use this article for personal use and teaching without any further permission. Please cite this article as follows (you will need to access the article online to obtain the date of publication). Mittal MK, Sloan JA, Rabinstein AA. Facebook: can it be a diagnostic tool for neurologists?. BMJ Case Reports 2012;10.1136/bcr-2012-006426, Published XXX Become a Fellow of BMJ Case Reports today and you can: ▸ Submit as many cases as you like ▸ Enjoy fast sympathetic peer review and rapid publication of accepted articles ▸ Access all the published articles ▸ Re-use any of the published material for personal use and teaching without further permission For information on Institutional Fellowships contact consortiasales@bmjgroup.com Visit casereports.bmj.com for more articles like this and to become a Fellow BMJ Case Reports 2012; doi:10.1136/bcr-2012-006426 3 of 3