SlideShare une entreprise Scribd logo

Data Mining & Signal Detection In Pv

•
•
Until ROI
Until ROI
Santé & MédecineTechnologieBusiness
1  sur  17
Dr. Bhaswat S. Chakraborty Senior VP, R&D, Cadila Pharmaceuticals January 22, 2009 Presented at Pharmacovigilance 2010, January 21-22, 2010
Risk Management and Pharmacovigilance ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
And Yet… ,[object Object],[object Object],[object Object],[object Object]
Two categories of approved drug ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Premature Approval? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Market Uptake and Sales Volume ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
J. Herson. In Data and Safety Monitoring Committees in Clinical Trials
Having an Adverse Events Database ,[object Object],[object Object],[object Object],[object Object],[object Object]
Desirable Attributes of AE Database Software ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Gavali, Kulkarni, Kumar and Chakraborty (2009), Ind J Pharmacol , 41, 162-166 or any comprehensive database Collection of ICSRs from CADRMP Conversion of free text to structured information Data cleaning and duplicate detection Applying quantitative or statistical methods Computing an accurate measure for SD
Targeted Event Y All other events Total Targeted Drug X A B A+B All other drugs C D C+D Total A+C B+D A+B+C+D
Criteria for a Toxic Disproportional ADR ,[object Object],[object Object],Significant disproportional Signal is detected when  2 is ≥ 4.0 and the rest ≥ 2.0
Casestudy Example: Propranolol-Bradycardia ,[object Object],[object Object],[object Object],[object Object],Gavali, Kulkarni, Kumar and Chakraborty (2009), Ind J Pharmacol , 41, 162-166 Bradycardia Not Bradycardia Propranolol HCL 4 82 Not Propranolol HCL 52 2749
Casestudy Examples – Significant Signals ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Source: LAREB
Thank You Very Much Acknowledgment: Sharwan Singhal

Recommandé

Evaluating and Investigating Drug Safety Signals with Public Databases
Evaluating and Investigating Drug Safety Signals with Public DatabasesEvaluating and Investigating Drug Safety Signals with Public Databases
Evaluating and Investigating Drug Safety Signals with Public DatabasesPerficient
 
Aggregate Reporting_Pharmacovigilance_Katalyst HLS
Aggregate Reporting_Pharmacovigilance_Katalyst HLSAggregate Reporting_Pharmacovigilance_Katalyst HLS
Aggregate Reporting_Pharmacovigilance_Katalyst HLSKatalyst HLS
 
Signal Detection in Pharmacovigilance - Process proposed by CIOMS Working Gro...
Signal Detection in Pharmacovigilance - Process proposed by CIOMS Working Gro...Signal Detection in Pharmacovigilance - Process proposed by CIOMS Working Gro...
Signal Detection in Pharmacovigilance - Process proposed by CIOMS Working Gro...Perficient
 
Data mining approaches to signal detection
Data mining approaches to signal detectionData mining approaches to signal detection
Data mining approaches to signal detectionBhaswat Chakraborty
 
General principles of Periodic Safety Update Reports(PSUR)Psur by Julia Appel...
General principles of Periodic Safety Update Reports(PSUR)Psur by Julia Appel...General principles of Periodic Safety Update Reports(PSUR)Psur by Julia Appel...
General principles of Periodic Safety Update Reports(PSUR)Psur by Julia Appel...László Árvai
 
Signal Detection & Management Strategies
Signal Detection & Management StrategiesSignal Detection & Management Strategies
Signal Detection & Management StrategiesFleming.
 
safety-aggregate-reporting-and-analytics-aag
safety-aggregate-reporting-and-analytics-aagsafety-aggregate-reporting-and-analytics-aag
safety-aggregate-reporting-and-analytics-aagSaba Anwer, MPH, MBA
 
Safety Reports: PBRER / PSUR
Safety Reports: PBRER / PSURSafety Reports: PBRER / PSUR
Safety Reports: PBRER / PSURAzierta
 

Recommandé

Evaluating and Investigating Drug Safety Signals with Public Databases
Evaluating and Investigating Drug Safety Signals with Public DatabasesEvaluating and Investigating Drug Safety Signals with Public Databases
Evaluating and Investigating Drug Safety Signals with Public DatabasesPerficient
 
Aggregate Reporting_Pharmacovigilance_Katalyst HLS
Aggregate Reporting_Pharmacovigilance_Katalyst HLSAggregate Reporting_Pharmacovigilance_Katalyst HLS
Aggregate Reporting_Pharmacovigilance_Katalyst HLSKatalyst HLS
 
Signal Detection in Pharmacovigilance - Process proposed by CIOMS Working Gro...
Signal Detection in Pharmacovigilance - Process proposed by CIOMS Working Gro...Signal Detection in Pharmacovigilance - Process proposed by CIOMS Working Gro...
Signal Detection in Pharmacovigilance - Process proposed by CIOMS Working Gro...Perficient
 
Data mining approaches to signal detection
Data mining approaches to signal detectionData mining approaches to signal detection
Data mining approaches to signal detectionBhaswat Chakraborty
 
General principles of Periodic Safety Update Reports(PSUR)Psur by Julia Appel...
General principles of Periodic Safety Update Reports(PSUR)Psur by Julia Appel...General principles of Periodic Safety Update Reports(PSUR)Psur by Julia Appel...
General principles of Periodic Safety Update Reports(PSUR)Psur by Julia Appel...László Árvai
 
Signal Detection & Management Strategies
Signal Detection & Management StrategiesSignal Detection & Management Strategies
Signal Detection & Management StrategiesFleming.
 
safety-aggregate-reporting-and-analytics-aag
safety-aggregate-reporting-and-analytics-aagsafety-aggregate-reporting-and-analytics-aag
safety-aggregate-reporting-and-analytics-aagSaba Anwer, MPH, MBA
 
Safety Reports: PBRER / PSUR
Safety Reports: PBRER / PSURSafety Reports: PBRER / PSUR
Safety Reports: PBRER / PSURAzierta
 
Pharmacovigilance Overview
Pharmacovigilance OverviewPharmacovigilance Overview
Pharmacovigilance OverviewSivasankaranV
 
Introduction to Pharmacovigilance Signal Detection
Introduction to Pharmacovigilance Signal DetectionIntroduction to Pharmacovigilance Signal Detection
Introduction to Pharmacovigilance Signal DetectionPerficient
 
E2B(R2) vs E2B(R3) ICSR ELEMENTS
E2B(R2) vs E2B(R3) ICSR ELEMENTSE2B(R2) vs E2B(R3) ICSR ELEMENTS
E2B(R2) vs E2B(R3) ICSR ELEMENTSAnurag Raghuvanshi
 
Drug Safety Regulations In The Us And Eu
Drug Safety Regulations In The Us And EuDrug Safety Regulations In The Us And Eu
Drug Safety Regulations In The Us And EuAngelinabarfield
 
Pharmacovigilance signal and signal detection
Pharmacovigilance signal and signal detectionPharmacovigilance signal and signal detection
Pharmacovigilance signal and signal detectionKiranRajput38
 
ICH - E2D Pharmacovigilance and Drug Safety - Professor Peivand Pirouzi
ICH - E2D Pharmacovigilance and Drug Safety - Professor Peivand PirouziICH - E2D Pharmacovigilance and Drug Safety - Professor Peivand Pirouzi
ICH - E2D Pharmacovigilance and Drug Safety - Professor Peivand PirouziPharmaceutical Compliance Inspection unit, Crown College of Canada
 
Signal detection and management
Signal detection and managementSignal detection and management
Signal detection and managementsekharbabu41
 
Quantitative methods of signal detection
Quantitative methods of signal detectionQuantitative methods of signal detection
Quantitative methods of signal detectionFrancois MAIGNEN
 
Presentation: Periodic safety update reports
Presentation: Periodic safety update reportsPresentation: Periodic safety update reports
Presentation: Periodic safety update reportsTGA Australia
 
Development safety update report (dsur) pharmacovigilance and safety
Development safety update report (dsur) pharmacovigilance and safetyDevelopment safety update report (dsur) pharmacovigilance and safety
Development safety update report (dsur) pharmacovigilance and safetyAzierta
 
Risk Management In Pharmacovigilance
Risk Management In PharmacovigilanceRisk Management In Pharmacovigilance
Risk Management In PharmacovigilanceRosmirella Cano Rojas
 
Periodic Safety Update Reports: Some commonly asked questions
Periodic Safety Update Reports: Some commonly asked questionsPeriodic Safety Update Reports: Some commonly asked questions
Periodic Safety Update Reports: Some commonly asked questionsTGA Australia
 
Pharmacovigilance
PharmacovigilancePharmacovigilance
PharmacovigilanceHesham Al-Khateeb
 
Medical Dictionary for Regulatory Activities (MedDRA)
Medical Dictionary for Regulatory Activities (MedDRA)Medical Dictionary for Regulatory Activities (MedDRA)
Medical Dictionary for Regulatory Activities (MedDRA)SMS MEDICAL COLLEGE
 
AN OVERVIEW AND IMPORTANCE OF PHARMACOVIGILANCE
AN OVERVIEW AND IMPORTANCE OF PHARMACOVIGILANCEAN OVERVIEW AND IMPORTANCE OF PHARMACOVIGILANCE
AN OVERVIEW AND IMPORTANCE OF PHARMACOVIGILANCERamakrishna K
 
Literature screening for pharmacovigilance 190818
Literature screening for pharmacovigilance 190818Literature screening for pharmacovigilance 190818
Literature screening for pharmacovigilance 190818Marnix Wieffer
 
Med dra Basics
Med dra BasicsMed dra Basics
Med dra BasicsSomnath Mondal
 
Periodic safety update reports – gvp guidelines and changes
Periodic safety update reports – gvp guidelines and changesPeriodic safety update reports – gvp guidelines and changes
Periodic safety update reports – gvp guidelines and changesTuracoz Healthcare Solutions
 
Practical Signal Management
Practical Signal ManagementPractical Signal Management
Practical Signal ManagementPerficient
 
DSUR
DSURDSUR
DSURDr.S.Gunasakaran, MD
 
Identifying Safety Signals by Data Mining the FDA Adverse Event Reporting Sys...
Identifying Safety Signals by Data Mining the FDA Adverse Event Reporting Sys...Identifying Safety Signals by Data Mining the FDA Adverse Event Reporting Sys...
Identifying Safety Signals by Data Mining the FDA Adverse Event Reporting Sys...Perficient, Inc.
 
Data mining in pharmacovigilance
Data mining in pharmacovigilanceData mining in pharmacovigilance
Data mining in pharmacovigilanceBhaswat Chakraborty
 

Contenu connexe

Tendances

Pharmacovigilance Overview
Pharmacovigilance OverviewPharmacovigilance Overview
Pharmacovigilance OverviewSivasankaranV
 
Introduction to Pharmacovigilance Signal Detection
Introduction to Pharmacovigilance Signal DetectionIntroduction to Pharmacovigilance Signal Detection
Introduction to Pharmacovigilance Signal DetectionPerficient
 
E2B(R2) vs E2B(R3) ICSR ELEMENTS
E2B(R2) vs E2B(R3) ICSR ELEMENTSE2B(R2) vs E2B(R3) ICSR ELEMENTS
E2B(R2) vs E2B(R3) ICSR ELEMENTSAnurag Raghuvanshi
 
Drug Safety Regulations In The Us And Eu
Drug Safety Regulations In The Us And EuDrug Safety Regulations In The Us And Eu
Drug Safety Regulations In The Us And EuAngelinabarfield
 
Pharmacovigilance signal and signal detection
Pharmacovigilance signal and signal detectionPharmacovigilance signal and signal detection
Pharmacovigilance signal and signal detectionKiranRajput38
 
Signal detection and management
Signal detection and managementSignal detection and management
Signal detection and managementsekharbabu41
 
Quantitative methods of signal detection
Quantitative methods of signal detectionQuantitative methods of signal detection
Quantitative methods of signal detectionFrancois MAIGNEN
 
Presentation: Periodic safety update reports
Presentation: Periodic safety update reportsPresentation: Periodic safety update reports
Presentation: Periodic safety update reportsTGA Australia
 
Development safety update report (dsur) pharmacovigilance and safety
Development safety update report (dsur) pharmacovigilance and safetyDevelopment safety update report (dsur) pharmacovigilance and safety
Development safety update report (dsur) pharmacovigilance and safetyAzierta
 
Risk Management In Pharmacovigilance
Risk Management In PharmacovigilanceRisk Management In Pharmacovigilance
Risk Management In PharmacovigilanceRosmirella Cano Rojas
 
Periodic Safety Update Reports: Some commonly asked questions
Periodic Safety Update Reports: Some commonly asked questionsPeriodic Safety Update Reports: Some commonly asked questions
Periodic Safety Update Reports: Some commonly asked questionsTGA Australia
 
Medical Dictionary for Regulatory Activities (MedDRA)
Medical Dictionary for Regulatory Activities (MedDRA)Medical Dictionary for Regulatory Activities (MedDRA)
Medical Dictionary for Regulatory Activities (MedDRA)SMS MEDICAL COLLEGE
 
AN OVERVIEW AND IMPORTANCE OF PHARMACOVIGILANCE
AN OVERVIEW AND IMPORTANCE OF PHARMACOVIGILANCEAN OVERVIEW AND IMPORTANCE OF PHARMACOVIGILANCE
AN OVERVIEW AND IMPORTANCE OF PHARMACOVIGILANCERamakrishna K
 
Literature screening for pharmacovigilance 190818
Literature screening for pharmacovigilance 190818Literature screening for pharmacovigilance 190818
Literature screening for pharmacovigilance 190818Marnix Wieffer
 
Periodic safety update reports – gvp guidelines and changes
Periodic safety update reports – gvp guidelines and changesPeriodic safety update reports – gvp guidelines and changes
Periodic safety update reports – gvp guidelines and changesTuracoz Healthcare Solutions
 
Practical Signal Management
Practical Signal ManagementPractical Signal Management
Practical Signal ManagementPerficient
 

Tendances (20)

Pharmacovigilance Overview
Pharmacovigilance OverviewPharmacovigilance Overview
Pharmacovigilance Overview
 
Introduction to Pharmacovigilance Signal Detection
Introduction to Pharmacovigilance Signal DetectionIntroduction to Pharmacovigilance Signal Detection
Introduction to Pharmacovigilance Signal Detection
 
E2B(R2) vs E2B(R3) ICSR ELEMENTS
E2B(R2) vs E2B(R3) ICSR ELEMENTSE2B(R2) vs E2B(R3) ICSR ELEMENTS
E2B(R2) vs E2B(R3) ICSR ELEMENTS
 
Drug Safety Regulations In The Us And Eu
Drug Safety Regulations In The Us And EuDrug Safety Regulations In The Us And Eu
Drug Safety Regulations In The Us And Eu
 
Pharmacovigilance signal and signal detection
Pharmacovigilance signal and signal detectionPharmacovigilance signal and signal detection
Pharmacovigilance signal and signal detection
 
ICH - E2D Pharmacovigilance and Drug Safety - Professor Peivand Pirouzi
ICH - E2D Pharmacovigilance and Drug Safety - Professor Peivand PirouziICH - E2D Pharmacovigilance and Drug Safety - Professor Peivand Pirouzi
ICH - E2D Pharmacovigilance and Drug Safety - Professor Peivand Pirouzi
 
Signal detection and management
Signal detection and managementSignal detection and management
Signal detection and management
 
Quantitative methods of signal detection
Quantitative methods of signal detectionQuantitative methods of signal detection
Quantitative methods of signal detection
 
Presentation: Periodic safety update reports
Presentation: Periodic safety update reportsPresentation: Periodic safety update reports
Presentation: Periodic safety update reports
 
Development safety update report (dsur) pharmacovigilance and safety
Development safety update report (dsur) pharmacovigilance and safetyDevelopment safety update report (dsur) pharmacovigilance and safety
Development safety update report (dsur) pharmacovigilance and safety
 
Risk Management In Pharmacovigilance
Risk Management In PharmacovigilanceRisk Management In Pharmacovigilance
Risk Management In Pharmacovigilance
 
Periodic Safety Update Reports: Some commonly asked questions
Periodic Safety Update Reports: Some commonly asked questionsPeriodic Safety Update Reports: Some commonly asked questions
Periodic Safety Update Reports: Some commonly asked questions
 
Pharmacovigilance
PharmacovigilancePharmacovigilance
Pharmacovigilance
 
Medical Dictionary for Regulatory Activities (MedDRA)
Medical Dictionary for Regulatory Activities (MedDRA)Medical Dictionary for Regulatory Activities (MedDRA)
Medical Dictionary for Regulatory Activities (MedDRA)
 
AN OVERVIEW AND IMPORTANCE OF PHARMACOVIGILANCE
AN OVERVIEW AND IMPORTANCE OF PHARMACOVIGILANCEAN OVERVIEW AND IMPORTANCE OF PHARMACOVIGILANCE
AN OVERVIEW AND IMPORTANCE OF PHARMACOVIGILANCE
 
Literature screening for pharmacovigilance 190818
Literature screening for pharmacovigilance 190818Literature screening for pharmacovigilance 190818
Literature screening for pharmacovigilance 190818
 
Med dra Basics
Med dra BasicsMed dra Basics
Med dra Basics
 
Periodic safety update reports – gvp guidelines and changes
Periodic safety update reports – gvp guidelines and changesPeriodic safety update reports – gvp guidelines and changes
Periodic safety update reports – gvp guidelines and changes
 
Practical Signal Management
Practical Signal ManagementPractical Signal Management
Practical Signal Management
 
DSUR
DSURDSUR
DSUR
 

En vedette

Identifying Safety Signals by Data Mining the FDA Adverse Event Reporting Sys...
Identifying Safety Signals by Data Mining the FDA Adverse Event Reporting Sys...Identifying Safety Signals by Data Mining the FDA Adverse Event Reporting Sys...
Identifying Safety Signals by Data Mining the FDA Adverse Event Reporting Sys...Perficient, Inc.
 
Data mining in pharmacovigilance
Data mining in pharmacovigilanceData mining in pharmacovigilance
Data mining in pharmacovigilanceBhaswat Chakraborty
 
Signal Detection Theory
Signal Detection TheorySignal Detection Theory
Signal Detection TheoryGauriSShrestha
 
Bayesian estimations of strong toxic signals [compatibility mode]
Bayesian estimations of strong toxic signals [compatibility mode]Bayesian estimations of strong toxic signals [compatibility mode]
Bayesian estimations of strong toxic signals [compatibility mode]Bhaswat Chakraborty
 
Reporting Methods _ Global Pharmacovigilance1
Reporting Methods _ Global Pharmacovigilance1Reporting Methods _ Global Pharmacovigilance1
Reporting Methods _ Global Pharmacovigilance1Hafsa Hafeez
 
Literature surveillance in pharmacovigilance
Literature surveillance in pharmacovigilanceLiterature surveillance in pharmacovigilance
Literature surveillance in pharmacovigilanceAnn-Marie Roche
 
Adverse Event Analysis
Adverse Event AnalysisAdverse Event Analysis
Adverse Event AnalysisSenthil Kumar
 
Freyr Pharmacolvigilance Brochure
Freyr Pharmacolvigilance BrochureFreyr Pharmacolvigilance Brochure
Freyr Pharmacolvigilance BrochureFaiz Shariff
 
Using Oracle Empirica Topics to Document Your Signal Management Process
Using Oracle Empirica Topics to Document Your Signal Management ProcessUsing Oracle Empirica Topics to Document Your Signal Management Process
Using Oracle Empirica Topics to Document Your Signal Management ProcessPerficient
 
Signal Detection With Oracle Products by Dipti Kadam, DBMS Consulting
Signal Detection With Oracle Products by Dipti Kadam, DBMS ConsultingSignal Detection With Oracle Products by Dipti Kadam, DBMS Consulting
Signal Detection With Oracle Products by Dipti Kadam, DBMS ConsultingUntil ROI
 
A Renaissance in Signal Management
A Renaissance in Signal Management A Renaissance in Signal Management
A Renaissance in Signal Management Sheila Rocchio
 
COORDINATION OF ACTUATED SIGNALS FOR A CORRIDOR
COORDINATION OF ACTUATED SIGNALS FOR A CORRIDORCOORDINATION OF ACTUATED SIGNALS FOR A CORRIDOR
COORDINATION OF ACTUATED SIGNALS FOR A CORRIDORRakesh Venkateswaran
 
Machine Learning and Optimization For Traffic and Emergency ...
Machine Learning and Optimization For Traffic and Emergency ...Machine Learning and Optimization For Traffic and Emergency ...
Machine Learning and Optimization For Traffic and Emergency ...butest
 
Periodic Safety Update Report (PSUR)
Periodic Safety Update Report (PSUR)Periodic Safety Update Report (PSUR)
Periodic Safety Update Report (PSUR)Dr. Rohith K Nair
 
Brandon Signals Council Presentation
Brandon Signals Council PresentationBrandon Signals Council Presentation
Brandon Signals Council PresentationCity Brandon
 
Pharmacovigilance - Processes & Challenges
Pharmacovigilance - Processes & ChallengesPharmacovigilance - Processes & Challenges
Pharmacovigilance - Processes & Challengespi
 
Urban Traffic Estimation & Optimization: An Overview
Urban Traffic Estimation & Optimization: An OverviewUrban Traffic Estimation & Optimization: An Overview
Urban Traffic Estimation & Optimization: An OverviewRakedet
 

En vedette (19)

Identifying Safety Signals by Data Mining the FDA Adverse Event Reporting Sys...
Identifying Safety Signals by Data Mining the FDA Adverse Event Reporting Sys...Identifying Safety Signals by Data Mining the FDA Adverse Event Reporting Sys...
Identifying Safety Signals by Data Mining the FDA Adverse Event Reporting Sys...
 
Data mining in pharmacovigilance
Data mining in pharmacovigilanceData mining in pharmacovigilance
Data mining in pharmacovigilance
 
Signal Detection Theory
Signal Detection TheorySignal Detection Theory
Signal Detection Theory
 
Bayesian estimations of strong toxic signals [compatibility mode]
Bayesian estimations of strong toxic signals [compatibility mode]Bayesian estimations of strong toxic signals [compatibility mode]
Bayesian estimations of strong toxic signals [compatibility mode]
 
Reporting Methods _ Global Pharmacovigilance1
Reporting Methods _ Global Pharmacovigilance1Reporting Methods _ Global Pharmacovigilance1
Reporting Methods _ Global Pharmacovigilance1
 
Literature surveillance in pharmacovigilance
Literature surveillance in pharmacovigilanceLiterature surveillance in pharmacovigilance
Literature surveillance in pharmacovigilance
 
Adverse Event Analysis
Adverse Event AnalysisAdverse Event Analysis
Adverse Event Analysis
 
Freyr Pharmacolvigilance Brochure
Freyr Pharmacolvigilance BrochureFreyr Pharmacolvigilance Brochure
Freyr Pharmacolvigilance Brochure
 
Using Oracle Empirica Topics to Document Your Signal Management Process
Using Oracle Empirica Topics to Document Your Signal Management ProcessUsing Oracle Empirica Topics to Document Your Signal Management Process
Using Oracle Empirica Topics to Document Your Signal Management Process
 
Signal Detection With Oracle Products by Dipti Kadam, DBMS Consulting
Signal Detection With Oracle Products by Dipti Kadam, DBMS ConsultingSignal Detection With Oracle Products by Dipti Kadam, DBMS Consulting
Signal Detection With Oracle Products by Dipti Kadam, DBMS Consulting
 
A Renaissance in Signal Management
A Renaissance in Signal Management A Renaissance in Signal Management
A Renaissance in Signal Management
 
adaptive signal control technology along sw 8th street pilot project
adaptive signal control technology along sw 8th street pilot projectadaptive signal control technology along sw 8th street pilot project
adaptive signal control technology along sw 8th street pilot project
 
COORDINATION OF ACTUATED SIGNALS FOR A CORRIDOR
COORDINATION OF ACTUATED SIGNALS FOR A CORRIDORCOORDINATION OF ACTUATED SIGNALS FOR A CORRIDOR
COORDINATION OF ACTUATED SIGNALS FOR A CORRIDOR
 
Machine Learning and Optimization For Traffic and Emergency ...
Machine Learning and Optimization For Traffic and Emergency ...Machine Learning and Optimization For Traffic and Emergency ...
Machine Learning and Optimization For Traffic and Emergency ...
 
Periodic Safety Update Report (PSUR)
Periodic Safety Update Report (PSUR)Periodic Safety Update Report (PSUR)
Periodic Safety Update Report (PSUR)
 
HySynth Pharmacovigilance
HySynth PharmacovigilanceHySynth Pharmacovigilance
HySynth Pharmacovigilance
 
Brandon Signals Council Presentation
Brandon Signals Council PresentationBrandon Signals Council Presentation
Brandon Signals Council Presentation
 
Pharmacovigilance - Processes & Challenges
Pharmacovigilance - Processes & ChallengesPharmacovigilance - Processes & Challenges
Pharmacovigilance - Processes & Challenges
 
Urban Traffic Estimation & Optimization: An Overview
Urban Traffic Estimation & Optimization: An OverviewUrban Traffic Estimation & Optimization: An Overview
Urban Traffic Estimation & Optimization: An Overview
 

Similaire à Data Mining & Signal Detection In Pv

Pharmacoepidemiology
PharmacoepidemiologyPharmacoepidemiology
PharmacoepidemiologyDivjyot Kaur
 
Pharmacoepidemiology
PharmacoepidemiologyPharmacoepidemiology
PharmacoepidemiologyDivjyot Kaur
 
3..Post marketing surveillance.pptx
3..Post marketing surveillance.pptx3..Post marketing surveillance.pptx
3..Post marketing surveillance.pptxKrishnapriyaVH1
 
Pharmacoepidemiology 110727114004-phpapp01
Pharmacoepidemiology 110727114004-phpapp01Pharmacoepidemiology 110727114004-phpapp01
Pharmacoepidemiology 110727114004-phpapp01Khadga Raj
 
PHARMACOVIGILANCE COMMON JOB INTERVIEW QUESTIONS WITH ANSWERS-Updated IN 202...
PHARMACOVIGILANCE COMMON JOB INTERVIEW QUESTIONS WITH ANSWERS-Updated IN 202...PHARMACOVIGILANCE COMMON JOB INTERVIEW QUESTIONS WITH ANSWERS-Updated IN 202...
PHARMACOVIGILANCE COMMON JOB INTERVIEW QUESTIONS WITH ANSWERS-Updated IN 202...Pristyn Research Solutions
 
Rochak presentation....current challenges of pharmacovegilence
Rochak presentation....current challenges of pharmacovegilenceRochak presentation....current challenges of pharmacovegilence
Rochak presentation....current challenges of pharmacovegilencerochaksoni
 
FREQUENTLY ASKED QUESTIONS IN PHARMACOVIGILANCE INTERVIEW AND ITS PREPARATION
FREQUENTLY ASKED QUESTIONS IN PHARMACOVIGILANCE INTERVIEW AND ITS PREPARATIONFREQUENTLY ASKED QUESTIONS IN PHARMACOVIGILANCE INTERVIEW AND ITS PREPARATION
FREQUENTLY ASKED QUESTIONS IN PHARMACOVIGILANCE INTERVIEW AND ITS PREPARATIONPristyn Research Solutions
 
FREQUENTLY ASKED QUESTIONS IN PHARMACOVIGILANCE INTERVIEWS & Its PREPARATIONS
FREQUENTLY ASKED QUESTIONS IN PHARMACOVIGILANCE INTERVIEWS & Its PREPARATIONSFREQUENTLY ASKED QUESTIONS IN PHARMACOVIGILANCE INTERVIEWS & Its PREPARATIONS
FREQUENTLY ASKED QUESTIONS IN PHARMACOVIGILANCE INTERVIEWS & Its PREPARATIONSJonaid Ali
 
PMS and Outsourcing - Copy.pptx
PMS and Outsourcing - Copy.pptxPMS and Outsourcing - Copy.pptx
PMS and Outsourcing - Copy.pptxMrRajanSwamiSwami
 
post marketing surveillance OF DRUG PRODUCTS
post marketing surveillance OF DRUG PRODUCTSpost marketing surveillance OF DRUG PRODUCTS
post marketing surveillance OF DRUG PRODUCTSPrakashGoudanavar
 
Cost on development of new drug
Cost on development of new drugCost on development of new drug
Cost on development of new drugDrAsimraza
 
New drug + Pharmacogenetics F22 TMSUc.pptx
New drug + Pharmacogenetics F22 TMSUc.pptxNew drug + Pharmacogenetics F22 TMSUc.pptx
New drug + Pharmacogenetics F22 TMSUc.pptxDrNabanitKumarJha1
 
Post marketing servillence
Post marketing servillencePost marketing servillence
Post marketing servillencebdvfgbdhg
 
Post marketing servillence
Post marketing servillencePost marketing servillence
Post marketing servillencebdvfgbdhg
 
Introduction to Regulatory Affairs - Pauwels Consulting Academy
Introduction to Regulatory Affairs - Pauwels Consulting AcademyIntroduction to Regulatory Affairs - Pauwels Consulting Academy
Introduction to Regulatory Affairs - Pauwels Consulting AcademyPauwels Consulting
 
Postmarket Surveillance Medical Devices
Postmarket Surveillance Medical DevicesPostmarket Surveillance Medical Devices
Postmarket Surveillance Medical DevicesJacobe2008
 
Accelerating Generic Approvals by Dr Anthony Crasto
Accelerating Generic Approvals by Dr Anthony CrastoAccelerating Generic Approvals by Dr Anthony Crasto
Accelerating Generic Approvals by Dr Anthony CrastoAnthony Melvin Crasto Ph.D
 
Challenges for drug development jsr slides aug 2013
Challenges for drug development jsr slides aug 2013Challenges for drug development jsr slides aug 2013
Challenges for drug development jsr slides aug 2013CincyTechUSA
 

Similaire à Data Mining & Signal Detection In Pv (20)

Pharmacoepidemiology
PharmacoepidemiologyPharmacoepidemiology
Pharmacoepidemiology
 
Pharmacoepidemiology
PharmacoepidemiologyPharmacoepidemiology
Pharmacoepidemiology
 
3..Post marketing surveillance.pptx
3..Post marketing surveillance.pptx3..Post marketing surveillance.pptx
3..Post marketing surveillance.pptx
 
Pharmacoepidemiology 110727114004-phpapp01
Pharmacoepidemiology 110727114004-phpapp01Pharmacoepidemiology 110727114004-phpapp01
Pharmacoepidemiology 110727114004-phpapp01
 
PHARMACOVIGILANCE COMMON JOB INTERVIEW QUESTIONS WITH ANSWERS-Updated IN 202...
PHARMACOVIGILANCE COMMON JOB INTERVIEW QUESTIONS WITH ANSWERS-Updated IN 202...PHARMACOVIGILANCE COMMON JOB INTERVIEW QUESTIONS WITH ANSWERS-Updated IN 202...
PHARMACOVIGILANCE COMMON JOB INTERVIEW QUESTIONS WITH ANSWERS-Updated IN 202...
 
Rochak presentation....current challenges of pharmacovegilence
Rochak presentation....current challenges of pharmacovegilenceRochak presentation....current challenges of pharmacovegilence
Rochak presentation....current challenges of pharmacovegilence
 
FREQUENTLY ASKED QUESTIONS IN PHARMACOVIGILANCE INTERVIEW AND ITS PREPARATION
FREQUENTLY ASKED QUESTIONS IN PHARMACOVIGILANCE INTERVIEW AND ITS PREPARATIONFREQUENTLY ASKED QUESTIONS IN PHARMACOVIGILANCE INTERVIEW AND ITS PREPARATION
FREQUENTLY ASKED QUESTIONS IN PHARMACOVIGILANCE INTERVIEW AND ITS PREPARATION
 
FREQUENTLY ASKED QUESTIONS IN PHARMACOVIGILANCE INTERVIEWS & Its PREPARATIONS
FREQUENTLY ASKED QUESTIONS IN PHARMACOVIGILANCE INTERVIEWS & Its PREPARATIONSFREQUENTLY ASKED QUESTIONS IN PHARMACOVIGILANCE INTERVIEWS & Its PREPARATIONS
FREQUENTLY ASKED QUESTIONS IN PHARMACOVIGILANCE INTERVIEWS & Its PREPARATIONS
 
PMS and Outsourcing - Copy.pptx
PMS and Outsourcing - Copy.pptxPMS and Outsourcing - Copy.pptx
PMS and Outsourcing - Copy.pptx
 
post marketing surveillance OF DRUG PRODUCTS
post marketing surveillance OF DRUG PRODUCTSpost marketing surveillance OF DRUG PRODUCTS
post marketing surveillance OF DRUG PRODUCTS
 
Pharmacovigilance: A review
Pharmacovigilance: A reviewPharmacovigilance: A review
Pharmacovigilance: A review
 
Cost on development of new drug
Cost on development of new drugCost on development of new drug
Cost on development of new drug
 
New drug + Pharmacogenetics F22 TMSUc.pptx
New drug + Pharmacogenetics F22 TMSUc.pptxNew drug + Pharmacogenetics F22 TMSUc.pptx
New drug + Pharmacogenetics F22 TMSUc.pptx
 
Post marketing servillence
Post marketing servillencePost marketing servillence
Post marketing servillence
 
Post marketing servillence
Post marketing servillencePost marketing servillence
Post marketing servillence
 
Introduction to Regulatory Affairs - Pauwels Consulting Academy
Introduction to Regulatory Affairs - Pauwels Consulting AcademyIntroduction to Regulatory Affairs - Pauwels Consulting Academy
Introduction to Regulatory Affairs - Pauwels Consulting Academy
 
Postmarket Surveillance Medical Devices
Postmarket Surveillance Medical DevicesPostmarket Surveillance Medical Devices
Postmarket Surveillance Medical Devices
 
Webinar: Investing $1.5b in A Sustainable Rare Disease Ecosystem
Webinar: Investing $1.5b in A Sustainable Rare Disease EcosystemWebinar: Investing $1.5b in A Sustainable Rare Disease Ecosystem
Webinar: Investing $1.5b in A Sustainable Rare Disease Ecosystem
 
Accelerating Generic Approvals by Dr Anthony Crasto
Accelerating Generic Approvals by Dr Anthony CrastoAccelerating Generic Approvals by Dr Anthony Crasto
Accelerating Generic Approvals by Dr Anthony Crasto
 
Challenges for drug development jsr slides aug 2013
Challenges for drug development jsr slides aug 2013Challenges for drug development jsr slides aug 2013
Challenges for drug development jsr slides aug 2013
 

Plus de Until ROI

WiMAX for BB India by Mr. Shyam Kaushal
WiMAX for BB India by Mr. Shyam KaushalWiMAX for BB India by Mr. Shyam Kaushal
WiMAX for BB India by Mr. Shyam KaushalUntil ROI
 
Ravi vs-prasad-speech-wimax-summit-2010
Ravi vs-prasad-speech-wimax-summit-2010Ravi vs-prasad-speech-wimax-summit-2010
Ravi vs-prasad-speech-wimax-summit-2010Until ROI
 
Mobile WiMAX drives speed to market for 4G networks By Data Sharan Mishra, Qtel
Mobile WiMAX drives speed to market for 4G networks By Data Sharan Mishra, QtelMobile WiMAX drives speed to market for 4G networks By Data Sharan Mishra, Qtel
Mobile WiMAX drives speed to market for 4G networks By Data Sharan Mishra, QtelUntil ROI
 
MAKING DEVICES WORK ON 4G NETWORKS by Dr. Rakesh Kushwaha CTO & Founder MFORM...
MAKING DEVICES WORK ON 4G NETWORKS by Dr. Rakesh Kushwaha CTO & Founder MFORM...MAKING DEVICES WORK ON 4G NETWORKS by Dr. Rakesh Kushwaha CTO & Founder MFORM...
MAKING DEVICES WORK ON 4G NETWORKS by Dr. Rakesh Kushwaha CTO & Founder MFORM...Until ROI
 
RURAL BROADBAND – from Digital Divide to Digital Dividend
RURAL BROADBAND – from Digital Divide to Digital DividendRURAL BROADBAND – from Digital Divide to Digital Dividend
RURAL BROADBAND – from Digital Divide to Digital DividendUntil ROI
 
Building Successful Wireless Broadband Services with WiMAX
Building Successful Wireless Broadband Services with WiMAXBuilding Successful Wireless Broadband Services with WiMAX
Building Successful Wireless Broadband Services with WiMAXUntil ROI
 
Volume 9 A Guidelines On Pharmacovigilance by Dr. Siddharth S Chachad, Medica...
Volume 9 A Guidelines On Pharmacovigilance by Dr. Siddharth S Chachad, Medica...Volume 9 A Guidelines On Pharmacovigilance by Dr. Siddharth S Chachad, Medica...
Volume 9 A Guidelines On Pharmacovigilance by Dr. Siddharth S Chachad, Medica...Until ROI
 
GROWTH OF PHARMACOVIGILANCE IN INDIA Dr Deven V Parmar MD Vice President – Gl...
GROWTH OF PHARMACOVIGILANCE IN INDIA Dr Deven V Parmar MD Vice President – Gl...GROWTH OF PHARMACOVIGILANCE IN INDIA Dr Deven V Parmar MD Vice President – Gl...
GROWTH OF PHARMACOVIGILANCE IN INDIA Dr Deven V Parmar MD Vice President – Gl...Until ROI
 
Pharmacovigilance in Focus by Dr.Prashant, Cipla
Pharmacovigilance in Focus by Dr.Prashant, CiplaPharmacovigilance in Focus by Dr.Prashant, Cipla
Pharmacovigilance in Focus by Dr.Prashant, CiplaUntil ROI
 
Challenges In Pharmacovigilance Dr Vishwas, by Dr. Vishwas Sovani MD ,VP P...
Challenges In Pharmacovigilance Dr Vishwas, by Dr. Vishwas Sovani MD ,VP P...Challenges In Pharmacovigilance Dr Vishwas, by Dr. Vishwas Sovani MD ,VP P...
Challenges In Pharmacovigilance Dr Vishwas, by Dr. Vishwas Sovani MD ,VP P...Until ROI
 
Enabling Risk Management: From Safety Signal to Risk/Benefit Management
Enabling Risk Management: From Safety Signal to Risk/Benefit ManagementEnabling Risk Management: From Safety Signal to Risk/Benefit Management
Enabling Risk Management: From Safety Signal to Risk/Benefit ManagementUntil ROI
 
Analysing the EU PVG regulations
Analysing the EU PVG regulationsAnalysing the EU PVG regulations
Analysing the EU PVG regulationsUntil ROI
 

Plus de Until ROI (12)

WiMAX for BB India by Mr. Shyam Kaushal
WiMAX for BB India by Mr. Shyam KaushalWiMAX for BB India by Mr. Shyam Kaushal
WiMAX for BB India by Mr. Shyam Kaushal
 
Ravi vs-prasad-speech-wimax-summit-2010
Ravi vs-prasad-speech-wimax-summit-2010Ravi vs-prasad-speech-wimax-summit-2010
Ravi vs-prasad-speech-wimax-summit-2010
 
Mobile WiMAX drives speed to market for 4G networks By Data Sharan Mishra, Qtel
Mobile WiMAX drives speed to market for 4G networks By Data Sharan Mishra, QtelMobile WiMAX drives speed to market for 4G networks By Data Sharan Mishra, Qtel
Mobile WiMAX drives speed to market for 4G networks By Data Sharan Mishra, Qtel
 
MAKING DEVICES WORK ON 4G NETWORKS by Dr. Rakesh Kushwaha CTO & Founder MFORM...
MAKING DEVICES WORK ON 4G NETWORKS by Dr. Rakesh Kushwaha CTO & Founder MFORM...MAKING DEVICES WORK ON 4G NETWORKS by Dr. Rakesh Kushwaha CTO & Founder MFORM...
MAKING DEVICES WORK ON 4G NETWORKS by Dr. Rakesh Kushwaha CTO & Founder MFORM...
 
RURAL BROADBAND – from Digital Divide to Digital Dividend
RURAL BROADBAND – from Digital Divide to Digital DividendRURAL BROADBAND – from Digital Divide to Digital Dividend
RURAL BROADBAND – from Digital Divide to Digital Dividend
 
Building Successful Wireless Broadband Services with WiMAX
Building Successful Wireless Broadband Services with WiMAXBuilding Successful Wireless Broadband Services with WiMAX
Building Successful Wireless Broadband Services with WiMAX
 
Volume 9 A Guidelines On Pharmacovigilance by Dr. Siddharth S Chachad, Medica...
Volume 9 A Guidelines On Pharmacovigilance by Dr. Siddharth S Chachad, Medica...Volume 9 A Guidelines On Pharmacovigilance by Dr. Siddharth S Chachad, Medica...
Volume 9 A Guidelines On Pharmacovigilance by Dr. Siddharth S Chachad, Medica...
 
GROWTH OF PHARMACOVIGILANCE IN INDIA Dr Deven V Parmar MD Vice President – Gl...
GROWTH OF PHARMACOVIGILANCE IN INDIA Dr Deven V Parmar MD Vice President – Gl...GROWTH OF PHARMACOVIGILANCE IN INDIA Dr Deven V Parmar MD Vice President – Gl...
GROWTH OF PHARMACOVIGILANCE IN INDIA Dr Deven V Parmar MD Vice President – Gl...
 
Pharmacovigilance in Focus by Dr.Prashant, Cipla
Pharmacovigilance in Focus by Dr.Prashant, CiplaPharmacovigilance in Focus by Dr.Prashant, Cipla
Pharmacovigilance in Focus by Dr.Prashant, Cipla
 
Challenges In Pharmacovigilance Dr Vishwas, by Dr. Vishwas Sovani MD ,VP P...
Challenges In Pharmacovigilance Dr Vishwas, by Dr. Vishwas Sovani MD ,VP P...Challenges In Pharmacovigilance Dr Vishwas, by Dr. Vishwas Sovani MD ,VP P...
Challenges In Pharmacovigilance Dr Vishwas, by Dr. Vishwas Sovani MD ,VP P...
 
Enabling Risk Management: From Safety Signal to Risk/Benefit Management
Enabling Risk Management: From Safety Signal to Risk/Benefit ManagementEnabling Risk Management: From Safety Signal to Risk/Benefit Management
Enabling Risk Management: From Safety Signal to Risk/Benefit Management
 
Analysing the EU PVG regulations
Analysing the EU PVG regulationsAnalysing the EU PVG regulations
Analysing the EU PVG regulations
 

Dernier

Russian Call Girls Chickpet - 7001305949 Booking and charges genuine rate for...
Russian Call Girls Chickpet - 7001305949 Booking and charges genuine rate for...Russian Call Girls Chickpet - 7001305949 Booking and charges genuine rate for...
Russian Call Girls Chickpet - 7001305949 Booking and charges genuine rate for...narwatsonia7
 
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbers
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbersBook Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbers
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbersnarwatsonia7
 
call girls in Connaught Place DELHI 🔝 >༒9540349809 🔝 genuine Escort Service ...
call girls in Connaught Place DELHI 🔝 >༒9540349809 🔝 genuine Escort Service ...call girls in Connaught Place DELHI 🔝 >༒9540349809 🔝 genuine Escort Service ...
call girls in Connaught Place DELHI 🔝 >༒9540349809 🔝 genuine Escort Service ...saminamagar
 
Call Girls Service in Virugambakkam - 7001305949 | 24x7 Service Available Nea...
Call Girls Service in Virugambakkam - 7001305949 | 24x7 Service Available Nea...Call Girls Service in Virugambakkam - 7001305949 | 24x7 Service Available Nea...
Call Girls Service in Virugambakkam - 7001305949 | 24x7 Service Available Nea...Nehru place Escorts
 
Case Report Peripartum Cardiomyopathy.pptx
Case Report Peripartum Cardiomyopathy.pptxCase Report Peripartum Cardiomyopathy.pptx
Case Report Peripartum Cardiomyopathy.pptxNiranjan Chavan
 
Statistical modeling in pharmaceutical research and development.
Statistical modeling in pharmaceutical research and development.Statistical modeling in pharmaceutical research and development.
Statistical modeling in pharmaceutical research and development.ANJALI
 
Call Girls Hsr Layout Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hsr Layout Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls Hsr Layout Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hsr Layout Just Call 7001305949 Top Class Call Girl Service Availablenarwatsonia7
 
Call Girls ITPL Just Call 7001305949 Top Class Call Girl Service Available
Call Girls ITPL Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls ITPL Just Call 7001305949 Top Class Call Girl Service Available
Call Girls ITPL Just Call 7001305949 Top Class Call Girl Service Availablenarwatsonia7
 
Call Girls Thane Just Call 9910780858 Get High Class Call Girls Service
Call Girls Thane Just Call 9910780858 Get High Class Call Girls ServiceCall Girls Thane Just Call 9910780858 Get High Class Call Girls Service
Call Girls Thane Just Call 9910780858 Get High Class Call Girls Servicesonalikaur4
 
Housewife Call Girls Bangalore - Call 7001305949 Rs-3500 with A/C Room Cash o...
Housewife Call Girls Bangalore - Call 7001305949 Rs-3500 with A/C Room Cash o...Housewife Call Girls Bangalore - Call 7001305949 Rs-3500 with A/C Room Cash o...
Housewife Call Girls Bangalore - Call 7001305949 Rs-3500 with A/C Room Cash o...narwatsonia7
 
Low Rate Call Girls Mumbai Suman 9910780858 Independent Escort Service Mumbai
Low Rate Call Girls Mumbai Suman 9910780858 Independent Escort Service MumbaiLow Rate Call Girls Mumbai Suman 9910780858 Independent Escort Service Mumbai
Low Rate Call Girls Mumbai Suman 9910780858 Independent Escort Service Mumbaisonalikaur4
 
High Profile Call Girls Mavalli - 7001305949 | 24x7 Service Available Near Me
High Profile Call Girls Mavalli - 7001305949 | 24x7 Service Available Near MeHigh Profile Call Girls Mavalli - 7001305949 | 24x7 Service Available Near Me
High Profile Call Girls Mavalli - 7001305949 | 24x7 Service Available Near Menarwatsonia7
 
call girls in paharganj DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in paharganj DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️call girls in paharganj DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in paharganj DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️saminamagar
 
Hemostasis Physiology and Clinical correlations by Dr Faiza.pdf
Hemostasis Physiology and Clinical correlations by Dr Faiza.pdfHemostasis Physiology and Clinical correlations by Dr Faiza.pdf
Hemostasis Physiology and Clinical correlations by Dr Faiza.pdfMedicoseAcademics
 
Call Girls Jayanagar Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Jayanagar Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls Jayanagar Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Jayanagar Just Call 7001305949 Top Class Call Girl Service Availablenarwatsonia7
 
Call Girls Hebbal Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hebbal Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls Hebbal Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hebbal Just Call 7001305949 Top Class Call Girl Service Availablenarwatsonia7
 
Call Girls Viman Nagar 7001305949 All Area Service COD available Any Time
Call Girls Viman Nagar 7001305949 All Area Service COD available Any TimeCall Girls Viman Nagar 7001305949 All Area Service COD available Any Time
Call Girls Viman Nagar 7001305949 All Area Service COD available Any Timevijaych2041
 
Call Girl Koramangala | 7001305949 At Low Cost Cash Payment Booking
Call Girl Koramangala | 7001305949 At Low Cost Cash Payment BookingCall Girl Koramangala | 7001305949 At Low Cost Cash Payment Booking
Call Girl Koramangala | 7001305949 At Low Cost Cash Payment Bookingnarwatsonia7
 
Mumbai Call Girls Service 9910780858 Real Russian Girls Looking Models
Mumbai Call Girls Service 9910780858 Real Russian Girls Looking ModelsMumbai Call Girls Service 9910780858 Real Russian Girls Looking Models
Mumbai Call Girls Service 9910780858 Real Russian Girls Looking Modelssonalikaur4
 
Glomerular Filtration and determinants of glomerular filtration .pptx
Glomerular Filtration and determinants of glomerular filtration .pptxGlomerular Filtration and determinants of glomerular filtration .pptx
Glomerular Filtration and determinants of glomerular filtration .pptxDr.Nusrat Tariq
 

Dernier (20)

Russian Call Girls Chickpet - 7001305949 Booking and charges genuine rate for...
Russian Call Girls Chickpet - 7001305949 Booking and charges genuine rate for...Russian Call Girls Chickpet - 7001305949 Booking and charges genuine rate for...
Russian Call Girls Chickpet - 7001305949 Booking and charges genuine rate for...
 
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbers
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbersBook Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbers
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbers
 
call girls in Connaught Place DELHI 🔝 >༒9540349809 🔝 genuine Escort Service ...
call girls in Connaught Place DELHI 🔝 >༒9540349809 🔝 genuine Escort Service ...call girls in Connaught Place DELHI 🔝 >༒9540349809 🔝 genuine Escort Service ...
call girls in Connaught Place DELHI 🔝 >༒9540349809 🔝 genuine Escort Service ...
 
Call Girls Service in Virugambakkam - 7001305949 | 24x7 Service Available Nea...
Call Girls Service in Virugambakkam - 7001305949 | 24x7 Service Available Nea...Call Girls Service in Virugambakkam - 7001305949 | 24x7 Service Available Nea...
Call Girls Service in Virugambakkam - 7001305949 | 24x7 Service Available Nea...
 
Case Report Peripartum Cardiomyopathy.pptx
Case Report Peripartum Cardiomyopathy.pptxCase Report Peripartum Cardiomyopathy.pptx
Case Report Peripartum Cardiomyopathy.pptx
 
Statistical modeling in pharmaceutical research and development.
Statistical modeling in pharmaceutical research and development.Statistical modeling in pharmaceutical research and development.
Statistical modeling in pharmaceutical research and development.
 
Call Girls Hsr Layout Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hsr Layout Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls Hsr Layout Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hsr Layout Just Call 7001305949 Top Class Call Girl Service Available
 
Call Girls ITPL Just Call 7001305949 Top Class Call Girl Service Available
Call Girls ITPL Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls ITPL Just Call 7001305949 Top Class Call Girl Service Available
Call Girls ITPL Just Call 7001305949 Top Class Call Girl Service Available
 
Call Girls Thane Just Call 9910780858 Get High Class Call Girls Service
Call Girls Thane Just Call 9910780858 Get High Class Call Girls ServiceCall Girls Thane Just Call 9910780858 Get High Class Call Girls Service
Call Girls Thane Just Call 9910780858 Get High Class Call Girls Service
 
Housewife Call Girls Bangalore - Call 7001305949 Rs-3500 with A/C Room Cash o...
Housewife Call Girls Bangalore - Call 7001305949 Rs-3500 with A/C Room Cash o...Housewife Call Girls Bangalore - Call 7001305949 Rs-3500 with A/C Room Cash o...
Housewife Call Girls Bangalore - Call 7001305949 Rs-3500 with A/C Room Cash o...
 
Low Rate Call Girls Mumbai Suman 9910780858 Independent Escort Service Mumbai
Low Rate Call Girls Mumbai Suman 9910780858 Independent Escort Service MumbaiLow Rate Call Girls Mumbai Suman 9910780858 Independent Escort Service Mumbai
Low Rate Call Girls Mumbai Suman 9910780858 Independent Escort Service Mumbai
 
High Profile Call Girls Mavalli - 7001305949 | 24x7 Service Available Near Me
High Profile Call Girls Mavalli - 7001305949 | 24x7 Service Available Near MeHigh Profile Call Girls Mavalli - 7001305949 | 24x7 Service Available Near Me
High Profile Call Girls Mavalli - 7001305949 | 24x7 Service Available Near Me
 
call girls in paharganj DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in paharganj DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️call girls in paharganj DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in paharganj DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
 
Hemostasis Physiology and Clinical correlations by Dr Faiza.pdf
Hemostasis Physiology and Clinical correlations by Dr Faiza.pdfHemostasis Physiology and Clinical correlations by Dr Faiza.pdf
Hemostasis Physiology and Clinical correlations by Dr Faiza.pdf
 
Call Girls Jayanagar Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Jayanagar Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls Jayanagar Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Jayanagar Just Call 7001305949 Top Class Call Girl Service Available
 
Call Girls Hebbal Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hebbal Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls Hebbal Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hebbal Just Call 7001305949 Top Class Call Girl Service Available
 
Call Girls Viman Nagar 7001305949 All Area Service COD available Any Time
Call Girls Viman Nagar 7001305949 All Area Service COD available Any TimeCall Girls Viman Nagar 7001305949 All Area Service COD available Any Time
Call Girls Viman Nagar 7001305949 All Area Service COD available Any Time
 
Call Girl Koramangala | 7001305949 At Low Cost Cash Payment Booking
Call Girl Koramangala | 7001305949 At Low Cost Cash Payment BookingCall Girl Koramangala | 7001305949 At Low Cost Cash Payment Booking
Call Girl Koramangala | 7001305949 At Low Cost Cash Payment Booking
 
Mumbai Call Girls Service 9910780858 Real Russian Girls Looking Models
Mumbai Call Girls Service 9910780858 Real Russian Girls Looking ModelsMumbai Call Girls Service 9910780858 Real Russian Girls Looking Models
Mumbai Call Girls Service 9910780858 Real Russian Girls Looking Models
 
Glomerular Filtration and determinants of glomerular filtration .pptx
Glomerular Filtration and determinants of glomerular filtration .pptxGlomerular Filtration and determinants of glomerular filtration .pptx
Glomerular Filtration and determinants of glomerular filtration .pptx
 

Data Mining & Signal Detection In Pv

  • 1. Dr. Bhaswat S. Chakraborty Senior VP, R&D, Cadila Pharmaceuticals January 22, 2009 Presented at Pharmacovigilance 2010, January 21-22, 2010
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
  • 7.  
  • 8.  
  • 9. J. Herson. In Data and Safety Monitoring Committees in Clinical Trials
  • 10.
  • 11.
  • 12. Gavali, Kulkarni, Kumar and Chakraborty (2009), Ind J Pharmacol , 41, 162-166 or any comprehensive database Collection of ICSRs from CADRMP Conversion of free text to structured information Data cleaning and duplicate detection Applying quantitative or statistical methods Computing an accurate measure for SD
  • 13. Targeted Event Y All other events Total Targeted Drug X A B A+B All other drugs C D C+D Total A+C B+D A+B+C+D
  • 14.
  • 15.
  • 16.
  • 17. Thank You Very Much Acknowledgment: Sharwan Singhal

Notes de l'éditeur

  1. Alosetron is indicated only for women with severe diarrhea-predominant irritable bowel syndrome (IBS). Grepafloxacin hydrochloride (trade name Raxar, Glaxo Wellcome) is an oral broad-spectrum quinoline antibiotic agent used to treat bacterial infection. Rofecoxib is a nonsteroidal anti-inflammatory drug (NSAId) that has now been withdrawn over safety concerns.
  2. Alosetron is indicated only for women with severe diarrhea-predominant irritable bowel syndrome (IBS). Grepafloxacin hydrochloride (trade name Raxar, Glaxo Wellcome) is an oral broad-spectrum quinoline antibiotic agent used to treat bacterial infection. Rofecoxib is a nonsteroidal anti-inflammatory drug (NSAId) that has now been withdrawn over safety concerns.
  3. In the USA, a black box warning (also sometimes called a black label warning or boxed warning ) is a type of warning that appears on the package insert for prescription drugs that may cause serious adverse effects. It is so named for the black border that usually surrounds the text of the warning.
  4. Proportional Reporting Ratio (PRR); Reporting Odds Ratio (ROR);