10. ALL INDIA INSTITUTE OF MEDICAL SCIENCES
DEPARTMENT OF NMR
Magnetic Resonance Imaging
•
High-resolution morphological
picture(anatomical structures)
•
Superior soft tissue contrast
•
Multi-planar imaging capability
•
MR images from protons present
water and fat of human tissues
•
Noninvasive – NO ionizing radiation
11. ALL INDIA INSTITUTE OF MEDICAL SCIENCES
DEPARTMENT OF NMR
T1 - weighted
Axial View
T1 - weighted
Coronal View
T1 - weighted
Sagittal View
12. ALL INDIA INSTITUTE OF MEDICAL SCIENCES
DEPARTMENT OF NMR
Effect of T2 relaxation on Contrast in MRI
Mineral water
Municipal water
13. ALL INDIA INSTITUTE OF MEDICAL SCIENCES
DEPARTMENT OF NMR
T1 - weighted - Axial
Tissues
Fat
WM
GM
CSF
T2 - weighted - Axial
PD
Light Gray
Gray
Light Gray
Gray
T1W
White
Light Gray
Gray
Black
Proton Density - Axial
T2W
Gray
Dark Gray
Gary
White
14. ALL INDIA INSTITUTE OF MEDICAL SCIENCES
DEPARTMENT OF NMR
High-Resolution - Image Details
Sella Sagittal
16. ALL INDIA INSTITUTE OF MEDICAL SCIENCES
DEPARTMENT OF NMR
Anaplastic astrocytoma
Metastatic brain
Glioblastoma
Low grade astroglia
Mixed Glioma
Low grade astrocytoma
17. MRI in the Diagnosis of Breast & Prostate Cancer
Breast -T1 - weighted
Breast - T2 - weighted
Prostate
T2 – weighted – Normal
Prostate
T2 – weighted - Tumor
19. ALL INDIA INSTITUTE OF MEDICAL SCIENCES
DEPARTMENT OF NMR
DTI- Diffusion
Tractography
Diffusion – weighted MRI
Volunteer
Patient
20. ALL INDIA INSTITUTE OF MEDICAL SCIENCES
DEPARTMENT OF NMR
CT
T2
DWI
Sensitivity of DWI for hyperacute stroke demonstrated in
57-year old patient. Unremarkable CT and T2 MRI. DWI
demonstrates hyperintense signal in left postcentral gyrus.
21. ALL INDIA INSTITUTE OF MEDICAL SCIENCES
DEPARTMENT OF NMR
Whole spine MRI
Cervical Spine Cord
compression
29. ALL INDIA INSTITUTE OF MEDICAL SCIENCES
DEPARTMENT OF NMR
Motor cortex activation
Both hands
Visual cortex activation
30. ALL INDIA INSTITUTE OF MEDICAL SCIENCES
DEPARTMENT OF NMR
fMRI during Sad
and Happy moods
Activation
in Amygdla
and Hippocampus
31. Liar versus Non-liar
THE TRUTH BE TOLD? [left] When the author was asked whether he had ever feigned illness to
escape an obligation, his prefrontal cortex showed no unusual activity.
LIAR, LIAR? [right] When the author was asked whether he had ever padded an expense report, his
prefrontal cortex became highly active [areas highlighted with hot colors].
33. Diffusion MRI in Breast Cancer
Responder
Poor responder
Pre therapy
1.07 x 10-3 mm2/s
0.98 x 10-3 mm2/s
II NACT
1.26 x 10-3 mm2/s
1.05 x 10-3 mm2/s
III NACT
1.60 x 10-3 mm2/s
1.20 x 10-3 mm2/s
34. ALL INDIA INSTITUTE OF MEDICAL SCIENCES
DEPARTMENT OF NMR
An
intraoperative
image
performed
revealing
residual
tumor
CE
images
show
location
of the
tumor
Magnet
lowered
tumor
resection
performed
Intra Operative MRI-1
Magnet
positioned
and
preoprative
images
obtained
35. ALL INDIA INSTITUTE OF MEDICAL SCIENCES
DEPARTMENT OF NMR
MRI
demonstrates
complete
resection of
tumor
Intra Operative MRI-2
Navigational
method
enables the
surgeon to
precisely
locate the
residual
tumor
Surgery
continues
using the guidance
of
intraoperative
navigation
36. Matrix coil technology
Peripheral
Angio coil
Head coil
MRI Scanner
Bilateral carotid coil
Bilateral carotid coil
Breast array coil for biopsy
Whole body MRI/A
37. ALL INDIA INSTITUTE OF MEDICAL SCIENCES
DEPARTMENT OF NMR
Can’t we NOT believe this? Science or Faith???
MRI Whole body
MRI Spine