Life sciences & health applications are driving biophotonics market growth. New technologies based on photon interaction with tissues will expand the biophotonics market from $23B in 2012 to $36B by 2017! Emerging technologies and applications will make Biophotonics a $36B market by 2017! The biophotonics market is estimated to grow from $23B in 2012 to $36B by 2017, with strong CAGR increases for emerging opportunities in imaging and sensing modalities. Once limited to hundreds or thousands of units/year in high-end desktop devices for life science and healthcare applications, biophotonics today has the potential to be a part of cost-effective devices targeting million-unit markets and open doors for new entrants. This report provides extensive market data in $M from 2011-2017, at different levels: from the total biophotonics-related market and the biophotonics system market to the biophotonics components and modules market. Diagnostic applications are paving the way for new optical technologies Over the last 20 years, Europe has faced increased growth of the pensioner population, recurrent epidemics, and economic issues linked to unsustainable, unbalanced healthcare systems. Today, healthcare is moving from a treatment-oriented system to a diagnosticoriented one, the end-goal being companion diagnostic, which is promising but still far away. The food sector faces growing demand for safer and healthier food, increased risk of epizootic diseases and food-related disorders, and threats to sustainable agricultural and fish production. All of these issues have in common a strong need to study real-time evolution of complete living organisms, or part of them (tissues, organs, cells, proteins, DNA, etc.). Therefore, it’s essential to develop technologies for quality and process control, as well as rapid microbiological methods suited to the entire production system. After providing an exclusive market segmentation, this report details the market drivers and technology trends for each application. One specific report section describes the following emerging applications: agri/agro food, personalized medicine, and home care. From bulky systems to portable devices Driven by these opportunities, numerous scientific fields have emerged in laboratories over the last 10 years: Raman imaging and sensing, photoacoustic tomography and microscopy, Terahertz imaging, and others. These sectors have benefited from huge telecommunications investments in sources, detectors and fibers developments (handheld spectroscopy, cytometry and microscopy on a chip, high-power fiber lasers for dermatologic treatments, photoacoustic imaging, enhanced sensibility in fluorescence-based tests, etc.). More information on that report at http://www.i-micronews.com/reports/Biophotonics-Market/4/360/

1. © 2013 copyright TEMATYS SARL, All rights reservedwww.tematys.com
Market research - Custom studies - Strategy & Decision making
Optics – Photonics – Sensors - Materials Engineering
Biophotonics Market
Technologies and Market Analysis
April 2013
Life Sciences & Health Applications are driving
the growth of the Biophotonics Market
Sample of the report

2. © 2013 copyright TEMATYS SARL, All rights reserved
Table of Contents
2
Executive Summary
Biophotonics Report
1. Introduction
 Context
 Study goals and objectives
 Information sources and
methodology
 Glossary
 List of companies
2. Biophotonics definition and
segmentation
 Biophotonics definition
 Biophotonics segmentation
3. Market Data
 Market definitions
 Total Biophotonics related market
 Biophotonics systems market
 Components and Modules
Biophotonics Market
 Optical vs non-optical markets
 Synthesis
 Scope of the report
4. Market Segmentation
 Segmentation of the Biophotonics
Market
 Segmentation of Life science & Health
market in this report
 Description of segments
 Market share

3. © 2013 copyright TEMATYS SARL, All rights reserved
Table of Contents
3
5. Emerging applications
 Tendencies
 Agri-agro food market
 Home care market
 Personalized medicine
6. Technologies overview
1. Introduction
2. In-vivo imaging
• Introduction
• Label-free technologies
– Optical Coherence Tomography
– Photoacoustic imaging
• Labeled technologies
– Fluorescence imaging
3. In-vitro analytics and sensing
• Introduction
• Label-free technologies
– Surface Plasmon Resonance (SPR)
– Raman spectroscopy
• Labeled technologies
– Cytometry
4. Conclusion / technology trends
7. Regulation aspects
8. Supply chain
 Supply chain analysis
 Investments in Biophotonics
 Conclusion
9. Conclusions
10. Appendices
 Market segmentations
 About TEMATYS
 About YOLE DÉVELOPPEMENT

4. © 2013 copyright TEMATYS SARL, All rights reserved
 Tematys and Yole Développement have decided to build this report in close
collaboration.
 This collaboration aims to provide you the most complete and valuable report by
combining the skills of our two companies.
 The combination of the strong technical knowledge of Tematys in optoelectronic
systems combined with the market and technology expertise of Yole
Développement at the device level has enable to get a great understanding of the
Biophotonics market.
Information sources and methodology
4

5. © 2013 copyright TEMATYS SARL, All rights reserved
List of companies cited in the report
5
Awaiba; Advantest; AES chemunex; AGFA HealthCare; Alere; Aptina; Avinger;
BD; Beckman Coulter; Biacore; Bio-Rad; Bruker; Caliper Life Science; Cobalt;
Cynosure; Endra Life Science; FOSS; Fujifilm; GE Healthcare; Heildelberg
Engineering; Horiba; Hoya; IBIS Technologies; Leica Microsystems; LI-COR;
LLTech; MedLumics; Merck Millipore; Michelson; MPA; Nikon; Nonin;
Olympus; OMRON; Optovue; Oxonica; Palomar; Partec; Perkin Elmer;
Prestodiag; Quanta System; Quantel Medical; Renishaw; Seattle Sensor
Systems; sensiQ; Sony; SpectraFluidics; St. Jude Medical; Thermofisher
scientific; Topcon; Tower jazz; Visualsonics; Volcano; Xfab; Zeiss
And many others…

6. © 2013 copyright TEMATYS SARL, All rights reserved
Life Science & Health
In-vivo In-vitro
Life science labs
Hospitals and clinics
Veterinaries
Physicians
Specialists
Patients
Biomedical analysis laboratories
Life science labs
Hospitals and clinics
Quality auditor
Patients
Veterinaries
Imaging
Diagnostic and analysis imaging systems
Surface imaging, inside imaging, see-through
imaging
Microscopy
Optical microscopy
Analytics, Sensing
Diagnostic sensing systems
Oximetry measurement
Analytical systems
Sequencing, cytometry, spectrometry,
biosensors.
Processing, Curing
Lasers processing & curing
Process treatment, laser surgery
6
Functions
Market
Location
Users segments
Life Science & Health segmentation
Final segmentation considered in the report

7. © 2013 copyright TEMATYS SARL, All rights reserved
Total Biophotonics related Market
Global Biophotonics Systems Market
Components and Modules
Biophotonics Market
+ Others System
Components
+ Power supply
+ Packaging
Global Biophotonics systems
market
+ consumable
+ reagents
Our vision of the market
7
Components and Modules
Biophotonics Market
Components directly
involved in optical
functions

8. © 2013 copyright TEMATYS SARL, All rights reserved
Total Biophotonics related Market in M$
8
0
5000
10000
15000
20000
25000
30000
35000
40000
2011 2012 2013 2014 2015 2016 2017
TotalBiophotonicsrelatedMarketinM$
Total Biophotonics related Market in M$
CAGR2012-2017= 9%

9. © 2013 copyright TEMATYS SARL, All rights reserved
Biophotonics Technologies Overview
9
The report provides an exclusive overview of the Biophotonics
technologies dedicated to In-vitro analytics & sensing
and in-vivo imaging.

10. © 2013 copyright TEMATYS SARL, All rights reserved 10
In-vitro sensing process for mentioned technologies
* If necessary
Filtration,
extraction*
Molecular
spectroscopy
No label
Surface chemistry no
label
Biosensors Filtration,
extraction*
Surface chemistry no
label
Cytometry
Sequencing
Filtration,
extraction*
Sample preparation
and PCR amplification
Sample preparation
No amplification
No label
Labeling
No label
Label
Technology Sample preparation Reagents (surface) Detection
Chemical reagents
and labels
Optical
Optical (fluo)
Electrochemical
Optical (fluo)
Electrochemical
Gravimetric
Optical (fluo)
Scattering
Optical (fluo)
Electrochemical
Magnetic and electro-
chemical biosensors
In-vitrosensingTechnologies
Optical

11. © 2013 copyright TEMATYS SARL, All rights reserved
Authors of the report
11
Jacques COCHARD founded TEMATYS in 2010,
a photonics dedicated market studies
company. He is managing the activities in
Technology Transfer, from academics to
companies. Jacques is directly in charge of the
Biophotonic activities at TEMATYS where he
has advised many companies in their
diversification from e.g. Telecom components
to Biophotonics market. Since 2006, he is a
member of the WorkGroup Biophotonic in the
European platform Photonics21. He is
Engineer from Ecole des Mines Nancy
(Material science).
Clementine BOUYE is analyst
in Tematys, specialised in
Biophotonics techologies and
markets. She is graduate from
Institute of Optics Graduate
Schol (IOGS) and ESPCI.
Benjamin ROUSSEL is a Market
Analyst at Yole Développement
involved in Microfluidic and Medical
Technologies fields. He holds a
pharmacy diploma from the
University Claude Bernard Lyon,
complemented by a master degree
in Technology and Innovation
Management from EMLyon Business
School.