- The document discusses the importance of considering global and local factors when conducting clinical research trials, including language, culture, and communication barriers. It emphasizes the need to adapt products, marketing, and processes to different markets. - Key recommendations include developing a clear global management strategy, benchmarking against other companies, engaging translation partners, centralizing content management, and considering diverse communication preferences across cultures. - Failure to account for these cultural and linguistic differences can lead to issues with accuracy of translations, informed consent from subjects, and understanding of products in local markets.

1. Being Smart About Global vs. Local During Clinical Research Trials Donald A. DePalma, PhD Chief Research Officer Copyright © 2008 by Common Sense Advisory, Inc.