SlideShare une entreprise Scribd logo
1  sur  20
Télécharger pour lire hors ligne
cGMP/GLP COMPLIANT       •   ISO 9001 CERTIFIED   •   FDA REGISTERED   •   DEA LICENSED




                                   Analytical Services




                                   Analytical Services




                                   Analytical Services
                                                                                        Deformulation




                                                                        Materials Identification




                                                                                     Failure Analysis




                                                                                 Litigation Support




                                                                                             Consulting




S C I E N T I F I C S O L U T I O N S W I T H PA S S I O N A N D P U R P O S E
WHAT’S YOUR CHEMICAL CHALLENGE?

For over 50 years Chemir Analytical Services
has been defining problems, developing solutions
and producing reliable, meaningful results for
nearly 7000 clients worldwide.
Analytical Services




Our independent non-routine analytical laboratory

solves challenging problems for such industries as food                            Analytical Services

and beverage, pharmaceutical, medical device, personal

care, polymers, plastics, packaging, coatings and more.


                                                                                   Analytical Services
OUR MISSION
We strive to maintain the highest degree of scientific
excellence, state-of-the-art instrumentation, quality
standards and customer service.                           ANALYTICAL SERVICES ................................2
                                                          -   Deformulation
                                                          -   Materials Identification




                                                                                                                  TA B L E O F C O N T E N T S
SCIENTIFIC EXCELLENCE                                     -   Contaminant Identification
Our team of scientists designs and implements             -   Failure Analysis
investigations that result in accurate,                   -   Industrial and Consumer Product Testing
reliable data with meaningful interpretations.
                                                          -   Polymer Analysis
                                                          -   Emergency Services
STATE-OF-THE-ART INSTRUMENTATION
Our instrumentation is maintained and calibrated          SOLUTIONS FOR INDUSTRY ........................6
regularly to ensure reliable results.
                                                          -   Food and Beverage
                                                          -   Home, Health and Beauty
FOCUS ON QUALITY                                          -   Pharmaceutical
Our facility is ISO 9001 certified, FDA registered        -   Medical Device
and cGMP/GLP compliant. Our quality mission
                                                          -   Plastics and Composites
is to achieve total customer satisfaction by
delivering on-time, accurate analyses that meet           -   Packaging
each customer’s needs.                                    -   Coatings, Adhesives and Sealants
                                                          -   Working Together
CUSTOMER SERVICE
                                                          LITIGATION SUPPORT
Our scientists ask the right questions, listen to our
clients, and provide practical solutions. Results are     AND CONSULTING ................................... 10

provided in a timeframe consistent with customer          - Litigation Support
requirements, including rush turnaround if needed.        - Consulting Services

                                                          Resources ........................................ 12
                                                          Customers ....................................... 14
                                                          Case Studies ................................... 16
                                                          Terms and Conditions ....................... 17




                                                                                                                                                 1
Chemir scientists take a customized approach to chemical
                                                    identification, deformulation and materials testing, utilizing
      A N A L Y T I C A L                           a wide variety of techniques and instrumentation.
      S E R V I C E S




              DEFORMULATION                                                 Unlike other deformulation providers, Chemir’s
                                                                            deliverable is a complete table of ingredients, including
              Deformulating products and materials is our specialty.
                                                                            quantities and percentages of components. After
              Also known as reverse engineering, deformulation
                                                                            contacting our clients to discuss the results, we provide
              is the separation, identification and quantitation of
                                                                            analysis and interpretations in a concise, bound final
              ingredients in a formulation.
                                                                            report containing a summary, conclusions and any
                                                                            original data.
              We have successfully deformulated a variety
              of products such as:
              - Drug products including oral, topical and liquid
                  dosages                                                   Deformulation analysis of commercial products is provided
              - Personal care products including topical gels,
                                                                            for informational purposes only. Chemir Analytical
                  lotions, creams and ointments
              - Detergents and cleansers                                    Services strongly recommends review of state and federal
              - Coatings
              - Adhesives (PSA, hot melt and water borne) and               laws, trademarks, copyrights and patent situations by the
                  sealants (Epoxy, PU, silicone)                            customer prior to use of such information.
              - Rubber products (natural rubber, EPDM, TPE,
                  Neoprene, SIS, SBS, NBR, EVA, PUR, silicone
                  and more)
              - Plastics (PP, PE, PMMA, Nylon, PU, flexible and             MATERIALS IDENTIFICATION
                  rigid PVC, copolymer and blends, degradable PP
                                                                            Materials identification can be used to determine the
                  and PE)
                                                                            components of an unknown material, confirm the
              - Specialty products (multiple layer films, high
                                                                            identity of a suspect material, or to identify differences
                  temperature engineered products)
                                                                            in similar materials.
              - Composites (glass reinforced, carbon or graphite
                  filled, Kevlar fiber reinforced and more)
                                                                            An unknown material is often the underlying cause
                                                                            of many difficult problems. The goal of material
              Our clients often come to us with a knowledge of the
                                                                            identification is to understand the chemistry of the
              types of ingredients in their target formula, such as
                                                                            major components. Chemir has developed expertise
              the wetting agent, co-solvent or surfactant. Using the
                                                                            in identifying and characterizing unknowns through
              client’s information along with our scientific expertise,
                                                                            analytical techniques and accurate interpretations.
              we can create a working “recipe” that meets a variety
              of needs including:
                                                                            We tackle organic material identification using FTIR
              - Competitive product characterization
                                                                            spectroscopy to determine the chemical family and
              - Identification of batch to batch variations
                                                                            functional groups through library matching and
              - Comparative analysis of “good” and “bad” samples
                                                                            fundamental spectral interpretation. We can also
              - Patent infringement litigation
                                                                            identify the inorganic components using an SEM
                                                                            equipped with an EDXA elemental analysis technique.
              Our experienced chemists are kept up-to-date with
              the latest methods and have developed techniques for
                                                                            Once the data is collected, our experienced scientists
              unraveling complicated formulations.
                                                                            interpret the information. They are skilled at effectively
                                                                            communicating information to our clients and
                                                                            providing useful results regarding the unknown material.




2   CHEMIR ANALYTICAL SERVICES     •   1.800.659.7659     •   WWW.CHEMIR.COM
Deformulation -
                                                                Materials Identification -
                                                             Contaminant Identification -




CONTAMINANT IDENTIFICATION

When an unknown material is found in a product,
manufacturers need to know the source of
contamination. Contaminant identification projects
involve the determination of components at low
concentrations such as ppm or even ppb levels.

A strategic technical approach is required to identify the
unknown contaminant by using a comparison study
between a control and suspect sample. The technical
approach is dependent on the sample matrix and the
suspected level of contamination. Often, we start with
a general screen of the control and suspect samples
using GC/MS and LC/MS. Depending on the results,
we may need to isolate the contaminant from a large
amount of sample to allow for analysis using FTIR
and NMR spectroscopy. Once identification is
complete, we can further quantify the contaminant
in the sample matrix.

Typical contaminant identification projects have
involved off-odor/flavor investigations, off-color
problems, or foreign particles in a product. Some
sources of contaminants have been from the
environment, improper storage of the product, or poor
quality raw materials. We work closely with our clients
to trace the source of contamination and develop a
corrective action program.




                                                                                      3
Our independent laboratory and expert scientists design
        A N A L Y T I C A L                          experiments that provide answers to industrial challenges.
        S E R V I C E S




                FAILURE ANALYSIS                                            INDUSTRIAL AND CONSUMER
                                                                            PRODUCT TESTING
                From consumer goods to industrial machinery, the
                scientists at Chemir Analytical Services can meet your      We provide customized product testing for individual
                failure analysis testing needs. We will help you define     components as well as finished manufactured products.
                the problem and recommend solutions. A product              We can investigate advertised product claims as well
                failure may include premature breakage, discoloration       as conduct performance comparisons. Other product
                or even an unexpected odor.                                 testing includes durability and resistance testing, as well
                                                                            as corrosion, chemical solvent resistance, stain and burn
                We can help with new or ongoing failures. A sample of       resistance, flammability, and fire properties.
                the “good” vs. “bad” product is often sent to our lab for
                comparison, but onsite investigations of processes may      The effects of the environment can have significant
                also be necessary.                                          impact on the lifetime and functionality of your
                                                                            product. Chemir can simulate environmental
                Products tested include packaging, plastics, adhesives,     conditions in order to understand the effect on
                metals, coatings, composites, laminates and more.           your product’s performance.

                Chemir’s final report includes conclusions, results         Testing services include:
                and all the original technical data acquired during the     - Degradation
                analysis including photographs, chromatograms and           - Product lifetime
                spectra. Our years of experience investigating material     - Product resistance
                and product failures allow us to recognize the indicators   - Weathering controlled accelerated exposure
                of failure and follow these leads to their root cause.
                                                                            Chemir has developed, validated and transferred
                                                                            methods for the analysis of inorganic materials. These
                                                                            include metals, sulfates, phosphates, chlorides, fluorides
                                                                            and other anions.

When unforeseen quality                                                     Materials tested include automotive parts, engines,
                                                                            fabrics, plastic components, toys, sporting goods
issues occur, Chemir can help.                                              and appliances.




  4   CHEMIR ANALYTICAL SERVICES    •   1.800.659.7659     •   WWW.CHEMIR.COM
Failure Analysis                                            -
                                      Industrial and Consumer Product Testing                                            -
                                                            Polymer Analysis                                             -
                                                          Emergency Services                                             -

POLYMER ANALYSIS                                          EMERGENCY SERVICES

When problems arise with the development, production      When unforeseen quality issues occur, Chemir can help.
or function of polymer based products, Chemir has the     Our scientists are available 24/7 to solve complex, non-
tools and experience to help. We have investigated a      routine problems using a customized approach.
wide range of polymeric materials including:
- Thermoplastics                                          Whether it is identifying the source of an off-odor
- Thermosets                                              or resolving a product failure, Chemir has a
- Elastomers                                              solid reputation for delivering results during
- High-performance polymers                               emergency situations.
- Specialty polymers
- Composites                                              Our analytical investigations provide quick and reliable
- Polyurethanes                                           answers needed to manage a crisis.
- Adhesives and sealants

Depending on our clients’ needs, we can offer a
strategic combination of physical and chemical testing
to answer specific questions. Physical properties
analyzed have included:
- Tensile properties
- Adhesive strength
- Compressibility
- Cross-sectional multiple layer film thickness
- Melt Flow Index
- Thermal properties (including glass transition,
    melting point, thermal expansion and crystallinity)

Our chemical testing capabilities range from obtaining
basic information to more detailed and structurally
specific results such as:
- Chemical family, including base polymer
   characterization
- Molecular weight distribution
- End group analysis
- Co-polymer backbone chemistry, comonomer
   contents/ratios, polymer blends
- Additive analysis




                                                                                                                     5
Our scientists investigate challenges with products
      S O L U T I O N S                             that impact health and well-being.
      F O R I N D U S T R Y




              FOOD AND BEVERAGE                                             HOME, HEALTH AND BEAUTY

              Chemir Analytical Services has helped hundreds of             Chemir has helped companies with challenging issues
              food and beverage manufacturers with challenging food         in the personal care, cosmetic, fragrance, soap and
              testing issues including:                                     detergent industries. We provide custom formulation,
              - Contaminant identification including ingredient             stability studies and pilot-scale, semi-commercial
                  cross-contamination                                       manufacturing.
              - Off-colors, off-flavors, or off-odors analysis
              - Packaging trouble-shooting                                  From concept to finished product, our formulation
              - Extractables and leachables testing                         scientists help manufacturers create new products or
              - Foreign object identification                               improve existing ones. Our staff has years of experience
              - Emergency response                                          working with a diversity of matrices. Unlike other
              - Hazard analysis                                             contract facilities, our clients retain the option to full
              - Toxicity risk assessment                                    rights of their final product formulation.

              In addition, our experts provide litigation support for       We also partner with personal care product
              food product liability issues and other legal challenges.     entrepreneurs, developers and marketing firms to take
                                                                            their ideas from concept to commercialization.
              Examples of ways we have helped food manufacturers:
              - Identified diet soda product contamination                  Chemir Analytical Services has assisted companies in
              - Determined the cause of bursting potato chip bags           the health and beauty industry by providing:
              - Analyzed levels of benzene in a beverage                    - Deformulation and reformulation of a
              - Off-odor source identification in produce                       discontinued product
              - Performed contaminant identification in an                  - Formulation development and pilot batch
                 imported food product                                          production of a mouthwash
              - Assisted poultry and meat processors with toxicity          - Investigation into an off-color nail polish
                 risk assessment                                            - Characterization of an unknown substance in a
                                                                                cosmetic product
                                                                            - Quantification of ingredients in a soap formulation




6   CHEMIR ANALYTICAL SERVICES     •   1.800.659.7659     •   WWW.CHEMIR.COM
Food and Beverage                              -
                                                                      Home, Health and Beauty                             -
                                                                               Pharmaceutical                             -
                                                                               Medical Device                             -

PHARMACEUTICAL                                            When medical device issues involve litigation support,
                                                          Chemir’s scientists are available to review data, provide
Our services to the pharmaceutical industry are focused
                                                          independent testing and offer expert witness services.
on solving difficult problems. Chemir scientists are
experienced at designing and performing investigative
                                                          Examples of problems solved for the medical
projects involving contamination or product failure
                                                          device industry:
issues. Our expertise in deformulation and polymer
                                                          - Analysis of polymeric materials to evaluate
analysis has provided many companies with solutions
                                                             products for resin composition
to troubling product challenges.
                                                          - Investigation of product failure of a
                                                             polyurethane catheter
Chemir also offers analysis and expert witness services
                                                          - Deformulation of a detector strip in support
for cases involving pharmaceutical patent infringement.
                                                             of an intellectual property case
Our chemists are experienced in the courtroom and are
                                                          - Polymer analysis to investigate biodegradation
skilled in explaining technical methods and results in
                                                             of an implanted device
clear and understandable terms.

Examples of pharmaceutical challenges Chemir
scientists have resolved include:                         Our facility is cGMP compliant, FDA registered
- Determination of the cause of black speck
    contaminants in aspirin                               and DEA licensed, and is centrally located in
- Deformulation of an OTC product for a                   St. Louis, Missouri.
    generic drug manufacturer
- Investigation into an off-color of a liquid
    pharmaceutical product
- Litigation support for a patent infringement case
    involving active pharmaceutical ingredients


MEDICAL DEVICE

Chemir Analytical Services investigates medical
device materials and performance issues
involving polymers, plastics, metals,
organics, inorganics and more. Our
scientists have solved difficult problems
with a wide variety of device products
including implantables, flexible tubing,
containers, protective devices, and more.




                                                                                                                      7
S O L U T I O N S                            Chemir has been solving tough problems for manufacturers for over 50 years.
      F O R I N D U S T R Y




              PLASTICS & COMPOSITES                                        PACKAGING

              Chemir offers a complete range of analyses for plastics      Packaging systems can pose challenging problems
              and composites. These materials can be found in a wide       for manufacturers. We solve complex problems with
              variety of industries including automotive, sporting         cartons, cans, bottles, pouches, vials, bags and more.
              goods, toys, industrial products, construction materials,    We have helped manufacturers in the research and
              consumer goods and more. Our scientists have                 development phases as well as trouble-shooting
              addressed issues such as:                                    finished products.
              - Premature breakage of a plastic tubing
              - Failure analysis of a cracking door                        Our comprehensive instrumentation, wide range
              - Deformulation of a competitor’s multi-layered              of capabilities and extensive experience enable us
                  film product                                             to test a package and also analyze its contents, labels,
              - Identification of the source of odor in a                  adhesives, closures, resins, pigments, additives,
                  children’s toy                                           shrink film and more.
              - Characterization of an unknown contaminant
                  in a polyurethane product                                Some examples of our problem solving capabilities
                                                                           include:
                                                                           - Determination of the cause of “ballooning”
                                                                              of a sealed pouch packaging system
                                                                           - Identification of the source of delamination
                                                                              of a multi-layered product package
                                                                           - Identification of the composition of a film that
                                                                              developed on a bottle after hot product filling
                                                                           - Deformulation of ink on a package label
                                                                           - Finding the cause of pinhole formation in bags
                                                                           - Comparison of two adhesive products to
                                                                              demonstrate a difference in the applied glues
                                                                           - Isolation of an unusual odor from a package
                                                                           - Testing of competing package sealing systems
                                                                              in a patent infringement case
                                                                           - Determination of the cause of adhesive failure
                                                                              occurring under high temperatures




                                                                            We have helped manufacturers
                                                                          in the research and development
                                                                                  phases as well as trouble-
                                                                                 shooting finished products.



8   CHEMIR ANALYTICAL SERVICES    •   1.800.659.7659    •   WWW.CHEMIR.COM
Plastics and Composites                                 -
                                                                                  Packaging                                 -
                                                          Coatings, Adhesives and Sealants                                  -
                                                                           Working Together                                 -




COATINGS, ADHESIVES AND SEALANTS                             CEOs/Presidents: Company leaders are most
                                                             concerned with risk, both financial and legal. Chemir
Our scientists investigate a wide variety of issues for
                                                             has worked with corporate executives faced with patent
the coating industry. We have helped manufacturers,
                                                             disputes, customer complaints, product liability cases,
distributors, importers and retailers with customized
                                                             safety concerns and more.
chemical analysis for:
 - Paints and coatings
                                                             Production Managers: When production lines are
- Adhesives and sealants
                                                             shut down or mechanical equipment malfunctions,
- Inks and dyes
                                                             managers need reliable answers. Chemir Analytical
- Other industrial chemicals
                                                             Services can perform investigations to determine
                                                             the root cause of failures, avoiding costly delays and
Chemir has helped companies with deformulation
                                                             resuming operations.
and reformulation of coatings products, as well as
trouble-shooting difficult challenges. We can also assist
                                                             Entrepreneurs/Research & Development: Chemir
with formulation projects, from bench scale up to
                                                             helps entrepreneurs accomplish their dreams. Our staff
toll production.
                                                             can develop an idea for a new product from bench-
WORKING TOGETHER
                                                             top to semi-commercial production. We have assisted
                                                             R&D departments research ingredients, determine
Our goal is to become an extension of your research,         procedures and make necessary adjustments to match
product development or quality control team. Clients         the customer’s idea.
come to Chemir from a broad spectrum of industries
and job functions.                                           A PARTNERSHIP

                                                             When you call our facility you are connected with a
Quality Assurance/Quality Control: Questions from
                                                             Director of Technical Services, an experienced scientist
QA/QC professionals often stem from unforeseen
                                                             who will ask the right questions, listen and develop
quality issues such as contamination, poor product
                                                             investigations to solve your problem. We are proud
performance or premature failure. Our scientists can
                                                             of our warm and personal service. Our scientific staff
help QA/QC develop and evaluate methods for
                                                             provides regular updates to our clients throughout the
a proactive quality program, as well as investigate
                                                             course of the project. Working as a partnership, we
unusual hard-to-solve problems.
                                                             can recommend changes in materials, reformulation or
                                                             manufacturing processes.




                                                                                                                        9
Complex problems may require outside experts. Chemir can provide testing
        L I T I G A T I O N
        S U P P O R T A N D                         and testimony in legal cases, as well as consulting on challenging issues.
        C O N S U L T I N G




                LITIGATION SUPPORT SERVICES                                 Our chemists have helped resolve issues in intellectual
                                                                            property disputes. As patent expert witnesses, our
                When challenges involve litigation, our scientists can
                                                                            scientists have offered testimony in patent infringement
                help. With experts in many disciplines and industries,
                                                                            disputes and trade secret litigation.
                we provide the technical and professional expertise
                necessary to support legal challenges. Ph.D. chemists
                                                                            Chemir’s materials scientists have also offered
                will design independent investigations, supervise
                                                                            forensic chemical and litigation support in product
                laboratory analyses and write comprehensive reports.
                                                                            liability defense cases, insurance claims and product
                They are skilled in explaining technical methods and
                                                                            failure litigation.
                results in clear and understandable terms.
                                                                            Some examples of litigation support projects:
                Litigation support services include:
                                                                            - Resolved a coatings patent infringement issue by
                - Evaluation of cases
                                                                              deformulation
                - Method development and testing
                                                                            - Resolved insurance claims for fire damages through
                - Interpretation of technical data
                                                                              analysis of explosives and fuels
                - Critical review of data
                                                                            - Expert consulting for chemical spill at a large
                - Literature searches
                                                                              company
                - Trial preparation
                                                                            - Performed failure analysis in a case involving
                - Depositions and trial testimony
                                                                              premature plastic pipe breakage
                                                                            - Reviewed opposing data in a personal injury lawsuit
                                                                            - Determined the root cause of failure for a window
                                                                              manufacturer in a product liability case
                                                                            - Conducted flame testing on a consumer product
                                                                              to support a client’s personal injury claim
With experts in many disciplines
and industries, we provide the
technical and professional
expertise necessary to support
legal challenges.




 10   CHEMIR ANALYTICAL SERVICES    •   1.800.659.7659    •   WWW.CHEMIR.COM
Litigation Support Services -
                                                                     Consulting Services -




CONSULTING SERVICES

Whether it is at your facility, here in our
laboratories, part of a conference call, or by
written report, Chemir’s staff is available for
consultation on a variety of projects. Our
independent consultants bring new perspectives and
experiences valuable for problem solving and product
improvement such as:
- Defining a manufacturing problem
- Working with your staff in problem solving
- Recommending different testing procedures
   or methods
- Defining research or quality protocols
- Providing expertise in product or process
   development
- Investigating a cause of product failure

Our consultants regularly participate in conferences
and panels in order to keep up with the latest
technical developments in their field and are regarded
as leaders in their respective industries. Our consulting
experience includes:
- Chemical analysis and techniques
- Polymers including deformulations, synthesis,
    additives, alloys, blends and formulations
- Consumer products
- Fine organic chemicals
- Polyolefins, nylons, multilayer films
- Advanced composites, carbon fibers
- Manufacturing processes




                                                                                     11
Our experienced staff of high level scientists, rigorous quality systems
                                                     and extensive instrumentation enables us to provide industry leading
       O U R                                         quality and service.
       R E S O U R C E S




               PEOPLE                                                         - Quality assurance coordinators to work closely
                                                                                with management and technical staff in reviewing
               Our staff of Ph.D-level chemists, along with advanced
                                                                                analyses for compliance with standards
               degreed scientists, collaborate to offer creative solutions
                                                                              - Quality team meetings to provide a forum for
               to non-routine problems. They bring practical industrial
                                                                                addressing questions and concerns on quality issues
               knowledge, as well as advanced academic
               credentials to each project.
                                                                              Ensuring Reliable Results: Our quality system is
                                                                              focused on obtaining accurate results.
               FACILITY                                                       - The use of Standard Operating Procedures (SOPs)
                                                                                 to ensure uniformity in routine operations
               Our centrally located facility in Maryland Heights,
                                                                              - Installation, Operation and Performance
               MO, a suburb of St. Louis, has more than 20,000 sq.
                                                                                 Qualification (IQ/OQ/PQ) of analytical
               ft. of laboratory space equipped with state-of-the-art
                                                                                 instrumentation for applicable regulatory work
               instrumentation.
                                                                              - The use of standard or validated methods for
                                                                                 analyses when available
               QUALITY                                                        - Continuing surveillance of published guidance
                                                                                 documents to ensure adherence to current regulatory
               Chemir Analytical Services maintains a Quality
                                                                                 policies that impact our clients
               Management System based on ISO 9001:2000 as well
               as other certifications.
                                                                              Error Free Reporting: The quality of our reported data
                                                                              is critical.
               Our quality system, documented procedures and
                                                                              - Documenting all facets of analysis
               analytical methods reflect our quality policy statement:
                                                                              - Communicating any questionable or non-
               To achieve total customer satisfaction by delivering on-
                                                                                  conformance results to the customer within 24 hours
               time, accurate analyses that meet each customer’s needs.
                                                                              - Following procedures and complying with standards
                                                                              - Auditing data internally when regulatory compliance
               The primary goals of our quality program are
                                                                                  is required
               continuous improvement, reliable results and on-time,
               error free reporting.
                                                                              Our facility is:
               Continual Improvement: We strive to improve                    -   ISO 9001:2000 Certified
               our processes, methods and procedures by the                   -   FDA Registered
               following means:                                               -   cGMP/GLP Compliant
               - Ongoing training programs to help us keep abreast
                                                                              -   DEA Licensed
                   of new technologies, regulations and industry trends
                   and to improve our processes




12   CHEMIR ANALYTICAL SERVICES     •   1.800.659.7659     •   WWW.CHEMIR.COM
People     -
                                                                                                             Facility   -
                                                                                                             Quality    -
                                                                                                          Equipment     -

EQUIPMENT                                                ATOMIC SPECTROSCOPY
                                                         Inductively Coupled Plasma/Optical Emission
Our clients can be assured their samples will be            Spectroscopy (ICP/OES)
investigated using state-of-the-art instrumentation in   Flame Atomic Emission Spectroscopy (Flame AES)
the areas of chromatography, spectroscopy, microscopy    Cold Vapor Atomic Absorption (CVAA)
and polymer testing. New equipment and regular
upgrades reflect Chemir’s commitment to customized       MICROSCOPY AND SURFACE ANALYSIS
solutions and scientific excellence.                     Optical Microscopy
                                                         Scanning Electron Microscopy/Energy
SEPARATIONS                                                 Dispersive X-ray Analysis (SEM/EDXA)
Gas Chromatography (GC)                                  Fourier Transform Infrared (FTIR)
   Sample Introduction Techniques                                 - Microscopy
        - Direct Liquid Injection                                 - Horizontal Attenuated Total Reflectance
        - Static Headspace                                          (HATR)
        - Solid Phase Microextraction (SPME)             Raman Microscopy
        - Purge and Trap
        - Pyrolysis                                      PHYSICAL AND THERMAL TESTING
   Detection Systems                                     Instron 1122/1125
        - Flame Ionization Detection (FID)               Melt Flow Index
        - Thermal Conductivity Detection (TCD)           Thermogravimetric Analysis (TGA)
        - Mass Spectrometry (MS)                         Differential Scanning Calorimetry (DSC)
Liquid Chromatography (LC)                               Modulated DSC (MDSC)
   Detection Systems                                     Dynamic Mechanical Analysis (DMA)
        - Spectrophotometric (UV-Vis)
        - Refractive Index (RI)                          WET CHEMICAL TECHNIQUES AND
        - Evaporative Light Scattering (ELSD)            OTHER EQUIPMENT
        - Electrospray Ionization-Ion Trap Mass          Karl Fischer Volumetric Titration
            Spectrometry (ESI-IT-MS)                     pH
        - Atmospheric Pressure Chemical Ionization-      Ion Selective Electrodes (ISE)
           Ion Trap Mass Spectrometry (APCI-IT-MS)       Soxhlet Extraction
Gel Permeation Chromatography (GPC)                      Accelerated Solvent Extraction
Ion Chromatography (IC)                                  Glass Capillary Viscometers
                                                         Brookfield Viscometers
MOLECULAR SPECTROSCOPY                                   Weathering Chambers
Ultraviolet-Visible Spectrophotometry (UV-Vis)           Zeta Potential
Fourier Transform Infrared Spectroscopy (FTIR)           Stability Chambers
Raman Spectroscopy
Nuclear Magnetic Resonance Spectroscopy (NMR)            Additionally, we have access to unique
         - Proton 400 MHz                                instrumentation at local universities and affiliate
         - Carbon 400 MHz                                facilities. When needed, we partner with outside
         - Multi Nuclear, 19F, 29Si, 31P, 15N, etc.      laboratories that have successfully passed our rigorous
         - Variable Temperature Capabilities             quality approval process.
         - 2D NMR (COSY, NOESY, HMQC,
           HMBC, TOCSY, HSQC)




                                                                                                                   13
O U R                                     Chemir has helped over 7,000 customers worldwide since 1959.
       C U S T O M E R S




               PARTIAL CLIENT LIST                                     -    Dowell Schlumberger, Inc.
                                                                       -    Dupont
               -   3M Corporation
                                                                       -    Duracell, Inc.
               -   ACH Food Companies
                                                                       -    Eaton Corporation
               -   Akin Gump Strauss Hauer & Feld LLP
                                                                       -    Emerson Electric
               -   AKZO Nobel-Fortafil Fibers, Inc.
                                                                       -    Exxon Chemical Company
               -   Alpha Plastics, Inc.
                                                                       -    FedEx
               -   Anheuser-Busch Companies
                                                                       -    FMC Corporation
               -   Archbald & Spray LLP
                                                                       -    GE Plastics
               -   Ashland Chemical
                                                                       -    GenCorp Polymer Products
               -   BASF Corporation
                                                                       -    General Polymers
               -   BF Goodrich Company
                                                                       -    Georgia-Pacific Corporation
               -   Borg-Warner Automotive
                                                                       -    Gillette Company
               -   Bostik, Inc.
                                                                       -    Graphic Packaging International, Inc.
               -   BP Chemicals, Inc.
                                                                       -    Gulf States Asphalt Co., Inc.
               -   Calgon Vestal Laboratories
                                                                       -    HB Fuller Company
               -   Cargill, Inc.
                                                                       -    Holland & Knight LLP
               -   Chevron Chemical
                                                                       -    Jones & Granger
               -   Colorite Plastics Company
                                                                       -    Jones Day
               -   Cozen O’Connor
                                                                       -    Latham & Watkins LLP
               -   Da/Pro Rubber Inc.
                                                                       -    MacDermid, Inc.
               -   Dow Chemical Company
                                                                       -    Mattel Toys, Inc.
                                                                       -    MEMC Electronic Materials, Inc.
                                                                       -    Monsanto
                                                                       -    Morton International
                                                                       -    Owens-Corning
                                                                       -    Perkin-Elmer
                                                                       -    Pillsbury Company
                                                                       -    PQ Corporation
                                                                       -    Pratt & Whitney
                                                                       -    Ralston Purina Company
                                                                       -    Rubbermaid Commercial Products
                                                                       -    Sonnenschein Nath & Rosenthal
                                                                       -    Therm-O-Disc, Inc.
                                                                       -    Ultradent Products, Incorporated
                                                                       -    United States Army Research Lab
                                                                       -    Valspar Corporation
                                                                       -    Velcro
                                                                       -    W.R. Grace & Company
                                                                       -    Zoltek Corporation




14   CHEMIR ANALYTICAL SERVICES   •   1.800.659.7659   •   WWW.CHEMIR.COM
Partial Client List -
                                                     What Customers Say About Chemir -




WHAT CUSTOMERS SAY ABOUT CHEMIR                               “Excellent follow-up. After analysis was complete, they
                                                              called me to discuss findings. Good personal touch.”
“Responsive, timely and good service.”                        Mark Magnussen, International Paper, Shelbyville, IL
Kaj Johnson, Method, San Francisco, CA
                                                              “Everything was professionally handled. The analysis
“Great customer and technical service staff. Very             was impressive”
knowledgeable and friendly. Enjoyed collaborating with        Robert C. Naylor, Jr., Pierre Foods, Cincinnati, OH
all Chemir staff.”
Marco Hobi, Devro Inc., Columbia, SC                          “Communication was excellent. It was never a problem
                                                              to get an update or an explanation. The testing was
“Answers! Several techniques used to get them. Good           done in a timely manner, as well as the final report.”
reports. Thoroughness in analysis.”                           Beth Gramza, Beiersdorf, Inc., Cincinnati, OH
Dr. Carolyn M. Primus, Primus Consulting,
Bradenton, FL                                                 “Timely, professional, satisfying and informative”
                                                              Randy Allen, Temple Inland,
“Exceptional service. Results delivered promptly              Humboldt Industrial Park, PA
and always on or before the promised date...very
professional and a pleasure to work with.”
Dr. Vikram Mehrotra, Monsanto, St. Louis, MO

“The staff was very helpful and the communication
was great.”
Burk Lattimore, Meadow Gold Dairies,                                         “Exceptional service.
Las Vegas, NV
                                                                       Results delivered promptly
“Friendly service, well-organized reports, quality results,
overall great experience.”                                              and always on or before
                                                                              the promised date.”
Robert Sorenson, Ultradent Products, South Jordan, UT

“Customer service. The quality of work was
outstanding!”
Timothy Jackson, Jr., FedEx, Memphis, TN




                                                                                                                        15
C A S E                                     Recent success stories illustrate Chemir’s experience and capabilities.
       S T U D I E S




               LEACHING FOOD PACKAGING                                     LITIGATION SUPPORT FOR A MANUFACTURER

               A frozen food manufacturer came to Chemir to                In a lawsuit against a glass-laminate manufacturer,
               determine if their “in-the-bag-cooking” packaging was       an installation contractor claimed that an incorrect
               contaminating the food during microwave cooking.            product formulation was the cause of product failure.
               Our expert scientists first analyzed the packaging and      The glass-polyester laminates had experienced serious
               then the microwaved food samples. Two components            discoloration, degradation, delamination and
               from the packaging were found to migrate into the food      hydrolysis. Our expert chemists performed a
               tested. One served as a flame retardant and the second      comparative analysis of a failed sample alongside a
               as a plasticizer. We then helped the client find a new      control sample. From the data, our scientists concluded
               packaging source that did not exhibit leaching, allowing    that the manufacturer used an incompatible UV
               them to resume production.                                  stabilizer along with an unstable polymer formulation.
                                                                           Chemir scientists presented this data and interpretations
               HEAT SEAL ADHESIVE FAILURE ANALYSIS                         as expert witness testimony for the installation
                                                                           contractor, resulting in a positive outcome for our client.
               Our client’s new heat seal adhesive was not providing a
               hermetic seal and released after only a few days. Faced
                                                                           EMERGENCY CONTAMINANT ANALYSIS
               with production line shut-down and delayed shipments,
               the customer called Chemir. They suspected that the         Chemir’s 24 hour emergency phone number was called
               new adhesive’s formula, a polyurethane-acrylic hot melt     on a Sunday afternoon. The door to a meat processing
               adhesive, was the reason for the failure. Our expert        plant was left open while a pesticide was being sprayed,
               chemists deformulated both the old formula and the          and they needed to determine if the product was
               new formula. The results showed significant differences     contaminated. Results were needed by the following
               in the molecular weight and molecular weight                morning, as 2000 butchers were holding operations.
               distribution, as well as the urethane-acrylic ratio.        After extracting the meat using a proprietary solvent,
               After concluding that these variations were the reason      Chemir used GC/MS to screen the extracts, looking
               for the adhesion failure, we recommended a formula          for the 3 main components of the pesticide. None were
               adjustment. The revised formula performed well, and         observed. We also intentionally spiked samples of meat
               the customer was able to resume operations.                 with pesticide, confirming the effectiveness of the test
                                                                           methods. The processor was able to resume operations
                                                                           on Monday morning.

                                                                           MEDICAL PLASTIC STABILITY

                                                                           A manufacturer of an implantable medical device
                                                                           needed to characterize several different polymers in
                                                                           order to identify the materials’ chemical changes over
                                                                           time. The manufacturer needed to know that the device
                                                                           would remain stable and effective inside patient’s bodies.
                                                                           Chemir’s scientists performed GPC analysis comparing
                                                                           the molecular weight of the polymers under various
                                                                           conditions, and were able to recommend an appropriate
                                                                           material selection.




16   CHEMIR ANALYTICAL SERVICES    •   1.800.659.7659    •   WWW.CHEMIR.COM
9.   Chemir reserves the right to subcontract Services to         COSTS AND PAYMENT
                                                                        other laboratories. If subcontracting is necessary,
                                                                        samples will be sent only to laboratories meeting            1.   Client agrees to pay all invoices within 15 days of
T E R M S A N D                                                         Chemir’s qualification requirements.                              invoice date.
                                                                                                                                     2.   In the event that payment is not received within 15
C O N D I T I O N S                                                LIABILITY
                                                                                                                                          days of invoice date, Client agrees to pay a late
                                                                                                                                          payment charge on the unpaid balance equal to
                                                                   1.   Chemir is not an insurer or a guarantor. Chemir                   1-1/2% per month.
                                                                        represents that the Services shall be performed              3.   All costs associated with compliance with any
SERVICES                                                                within the limits mutually agreed to, in writing, and             subpoena(s) for documents, testimony in court of law,
                                                                        in a manner consistent with the level of care and skill           or for any other purpose relating to Services performed
1.   Client acknowledges that Chemir Analytical Services,               ordinarily exercised by providers of similar services             by Chemir for Client, shall be paid by Client. Client
     Inc. and/or its affiliates (together, “Chemir”) performs           under similar circumstances. No other representations             shall also pay Chemir’s then existing standard fees
     analysis and testing services (the “Services”) only as             or warranties, express or implied, are included or                for consulting, deposition and trial testimony and all
     specified in writing by Client. Chemir does not design,            intended in this agreement, or in any report, opinion or          expenses related thereto.
     warrant, supervise or monitor compliance of products or            document related to the Services provided hereunder.         4.   Project specific supplies including, but not limited to,
     services except as specifically agreed to in writing prior    2.   For the safety of Chemir’s personnel, Client must advise          standards, raw materials, shipping, columns and/or
     to the performance of the Services. Client acknowledges            Chemir if samples are known or suspected to contain               specialty chemicals and supplies required for execution
     that, by their very nature, the Services are limited in            hazardous substances. Material Safety Data Sheets                 of a Client’s project will be purchased by Chemir and
     scope and subject to expected measurement variability.             must be provided if available.                                    billed to Client as pass-through costs. If necessary,
2.   Samples and portions thereof not destroyed in the             3.   Client understands and agrees that Chemir, in entering            Chemir may bill a waste disposal fee of up to 5% of
     performance of the Services remain the property of the             into this Contract and by performing Services, does not           total project cost or $500.00, whichever is lower, to
     Client, are retained a maximum of 30 days after project            assume, abridge, abrogate or undertake to discharge               cover proper sample and chemical disposal.
     completion, unless instructed otherwise in writing by              any duty or responsibility of Client to any other party or   5.   Chemir reserves the right to request a prepayment from
     Client, and thereafter will be disposed of or returned             parties. No one other than Client shall have any right            Client prior to initiating project work.
     to Client, at Client’s expense. A sample storage fee of            to rely on any report issued by Chemir. Client agrees,       6.   Should Client cancel all or a portion of the project after
     $200.00 per month will be applied on requests for                  in consideration of Chemir undertaking to perform                 the project has been initiated, Client will be liable to
     storage past 30 days after project completion.                     the Services hereunder, to protect, defend, indemnify,            Chemir for all hours expended on the project up to the
3.   Unless otherwise specified therein in writing, nothing             save harmless and exonerate Chemir from any and                   time of cancellation, at a rate of $385.00 per hour, plus
     contained in any report issued by Chemir shall be                  all claims, damages, including lost profits, expenses,            all project specific supplies at cost, or a minimum of
     deemed to imply or mean that Chemir conducts any                   including attorney’s fees, either direct or consequential,        25% of the estimated project cost as a fee for Chemir’s
     quality control program for the Client to whom the                 for any and all injuries to persons, including the                mobilization on the project, whichever is greater. This
     report is issued.                                                  personnel of Chemir, or property arising out of or in             cancellation charge is a fee for work performed and is
4.   Reports issued by Chemir are for the exclusive use of              consequence of the performance of the Services and/or             not regarded as liquidated damages.
     the Client to whom they are addressed. Reports and                 the performance of the samples tested hereunder.
     the name Chemir, or its seals or insignias, are not to be     4.   Client agrees that if Chemir should be found liable for      MISCELLANEOUS
     used by or on behalf of Client under any circumstances             any losses or damages attributable to the Services in
     for any purpose whatsoever, including but not limited                                                                           1.   This agreement and any and all claims and disputes
                                                                        any respect, Chemir’s liability shall in no event exceed
     to use in advertising, publicity material or in any other                                                                            hereunder or related thereto shall be governed by the
                                                                        the amount of the fee paid by Client for such Services
     manner without Chemir’s prior written approval.                                                                                      internal laws of the State of Missouri. Chemir and Client
                                                                        and Client’s sole remedy at law or in equity shall be the
5.   Reports issued by Chemir apply only to the standards                                                                                 agree that exclusive jurisdiction and venue for any
                                                                        right to recover up to such amount. Client acknowledges
     or procedures identified therein and to the sample(s)                                                                                and all such claims and disputes shall be in St. Louis
                                                                        and agrees that in no event will Chemir be liable for
     tested.                                                                                                                              County, Missouri.
                                                                        consequential or incidental damages or expenses,
6.   Chemir shall retain copies of reports for a period of five                                                                      2.   In the event that Chemir prevails in any dispute
                                                                        including, but not limited to lost profits.
     years, after which such reports will be destroyed.                                                                                   or claim, including the collection of monies from
                                                                   5.   Whenever performance by either party is delayed or
7.   Unless specified in a report in writing, the analysis and                                                                            Client, Client agrees that Client will pay any and all
                                                                        prevented by war, insurrection, fire or other casualty,
     testing results are not indicative or representative of the                                                                          expenses, including collection costs and attorney’s fees,
                                                                        strikes or embargoes, shortage of transportation
     qualities of the lot from which the sample was taken or                                                                              reasonably incurred in the prosecution or defense of
                                                                        facilities or any other similar or dissimilar causes,
     of apparently identical or similar products.                                                                                         such claim, dispute or collection.
                                                                        beyond the control of such party, such delay
8.   Deformulation analysis of commercial products is                                                                                3.   The terms and conditions contained herein, together
                                                                        or prevention shall be excused and the time of
     provided for informational purposes only. Chemir                                                                                     with Chemir’s quotation and offer of Services to Client,
                                                                        performance hereunder extended for the duration
     strongly recommends review of state and federal laws,                                                                                and Client’s acceptance of such offer, shall constitute
                                                                        of the causative factor.
     trademarks, copyrights and patent situations by the                                                                                  the entire agreement between Chemir and Client. Any
     Client prior to use of such information.                                                                                             conflicting terms contained in any order or acceptance
                                                                                                                                          submitted by Client shall be null and void.




                                          Analytical Services




                                          Analytical Services
Analytical Services




2672 Metro Blvd

M a r y l a n d H e i g h t sA n a Oy t i3 0 4 3S e r v i c e s
                             , M l 6 cal


toll-free 800.659.7659

tel 314.291.6620

fax 314.291.6630
               Analytical Services

e m a i l i n f o @ c h e m i r. c o m

w e b w w w. c h e m i r. c o m

Contenu connexe

Tendances

從臨床實務看醫材行銷活動
從臨床實務看醫材行銷活動從臨床實務看醫材行銷活動
從臨床實務看醫材行銷活動wei-zen sun
 
Quality systems v3
Quality systems v3Quality systems v3
Quality systems v3Ravi Pamnani
 
Qp 020 12 Cleanergetic Solar Services Presentation V1
Qp 020 12 Cleanergetic Solar Services Presentation V1Qp 020 12 Cleanergetic Solar Services Presentation V1
Qp 020 12 Cleanergetic Solar Services Presentation V1Antonio Bautista, Ph.D.
 
final main book
final main bookfinal main book
final main bookamitkahire
 
REACH Report.PDF
REACH Report.PDFREACH Report.PDF
REACH Report.PDFDaisy Jiang
 
Protect your brand get to market faster be more competitive
Protect your brand get to market faster be more competitiveProtect your brand get to market faster be more competitive
Protect your brand get to market faster be more competitiveIntertek CE
 

Tendances (7)

從臨床實務看醫材行銷活動
從臨床實務看醫材行銷活動從臨床實務看醫材行銷活動
從臨床實務看醫材行銷活動
 
Quality systems v3
Quality systems v3Quality systems v3
Quality systems v3
 
Qp 020 12 Cleanergetic Solar Services Presentation V1
Qp 020 12 Cleanergetic Solar Services Presentation V1Qp 020 12 Cleanergetic Solar Services Presentation V1
Qp 020 12 Cleanergetic Solar Services Presentation V1
 
final main book
final main bookfinal main book
final main book
 
REACH Report.PDF
REACH Report.PDFREACH Report.PDF
REACH Report.PDF
 
Protect your brand get to market faster be more competitive
Protect your brand get to market faster be more competitiveProtect your brand get to market faster be more competitive
Protect your brand get to market faster be more competitive
 
pc2011
pc2011pc2011
pc2011
 

En vedette

Pen and Ink Drawing
Pen and Ink DrawingPen and Ink Drawing
Pen and Ink Drawingmeier106
 
Drawing with Ink: Variety of Line and Cross-Hatching (Pen and Brush)
Drawing with Ink: Variety of Line and Cross-Hatching (Pen and Brush)Drawing with Ink: Variety of Line and Cross-Hatching (Pen and Brush)
Drawing with Ink: Variety of Line and Cross-Hatching (Pen and Brush)glennhirsch
 
Effective day-to-day category management by BearingPoint
Effective day-to-day category management by BearingPointEffective day-to-day category management by BearingPoint
Effective day-to-day category management by BearingPointJari Laine
 
110118 Presentasion Proposal Thesis Print
110118 Presentasion Proposal Thesis Print110118 Presentasion Proposal Thesis Print
110118 Presentasion Proposal Thesis PrintReggy Lu
 
Newsletter sample
Newsletter sampleNewsletter sample
Newsletter sampleguest986419
 
מציאות ברשת
מציאות ברשתמציאות ברשת
מציאות ברשתiTalent
 
NeoLibre for a Private University
NeoLibre for a Private UniversityNeoLibre for a Private University
NeoLibre for a Private UniversityNeoLibre
 
Photo Composition
Photo CompositionPhoto Composition
Photo Compositionaking29
 
Cubicle Concept for FARAM
Cubicle Concept for FARAMCubicle Concept for FARAM
Cubicle Concept for FARAMguest932fbce
 
9th Agenda For 3 8 10
9th Agenda For 3 8 109th Agenda For 3 8 10
9th Agenda For 3 8 10guest70534bf
 
Primera Gala de Alumnas
Primera Gala de AlumnasPrimera Gala de Alumnas
Primera Gala de AlumnasPaula Velozo
 
navo - presentazione
navo - presentazionenavo - presentazione
navo - presentazionenavo
 
U N I T 10 C O N D I T I O N A L S G O L D I N T E R M E D I A T E ...
U N I T 10     C O N D I T I O N A L S    G O L D  I N T E R M E D I A T E   ...U N I T 10     C O N D I T I O N A L S    G O L D  I N T E R M E D I A T E   ...
U N I T 10 C O N D I T I O N A L S G O L D I N T E R M E D I A T E ...tsisves
 
Presentatie
PresentatiePresentatie
PresentatieScholtes
 

En vedette (20)

Pen and Ink Drawing
Pen and Ink DrawingPen and Ink Drawing
Pen and Ink Drawing
 
Drawing with Ink: Variety of Line and Cross-Hatching (Pen and Brush)
Drawing with Ink: Variety of Line and Cross-Hatching (Pen and Brush)Drawing with Ink: Variety of Line and Cross-Hatching (Pen and Brush)
Drawing with Ink: Variety of Line and Cross-Hatching (Pen and Brush)
 
Effective day-to-day category management by BearingPoint
Effective day-to-day category management by BearingPointEffective day-to-day category management by BearingPoint
Effective day-to-day category management by BearingPoint
 
110118 Presentasion Proposal Thesis Print
110118 Presentasion Proposal Thesis Print110118 Presentasion Proposal Thesis Print
110118 Presentasion Proposal Thesis Print
 
Newsletter sample
Newsletter sampleNewsletter sample
Newsletter sample
 
מציאות ברשת
מציאות ברשתמציאות ברשת
מציאות ברשת
 
NeoLibre for a Private University
NeoLibre for a Private UniversityNeoLibre for a Private University
NeoLibre for a Private University
 
Giovanni
GiovanniGiovanni
Giovanni
 
Hpm2010seminar2
Hpm2010seminar2Hpm2010seminar2
Hpm2010seminar2
 
Photo Composition
Photo CompositionPhoto Composition
Photo Composition
 
Cubicle Concept for FARAM
Cubicle Concept for FARAMCubicle Concept for FARAM
Cubicle Concept for FARAM
 
9th Agenda For 3 8 10
9th Agenda For 3 8 109th Agenda For 3 8 10
9th Agenda For 3 8 10
 
Heat Yan 12
Heat Yan 12Heat Yan 12
Heat Yan 12
 
Primera Gala de Alumnas
Primera Gala de AlumnasPrimera Gala de Alumnas
Primera Gala de Alumnas
 
Mini Lesson
Mini LessonMini Lesson
Mini Lesson
 
navo - presentazione
navo - presentazionenavo - presentazione
navo - presentazione
 
U N I T 10 C O N D I T I O N A L S G O L D I N T E R M E D I A T E ...
U N I T 10     C O N D I T I O N A L S    G O L D  I N T E R M E D I A T E   ...U N I T 10     C O N D I T I O N A L S    G O L D  I N T E R M E D I A T E   ...
U N I T 10 C O N D I T I O N A L S G O L D I N T E R M E D I A T E ...
 
Never Gonna Be Alone
Never Gonna Be AloneNever Gonna Be Alone
Never Gonna Be Alone
 
Presentatie
PresentatiePresentatie
Presentatie
 
Twitter library talk
Twitter library talkTwitter library talk
Twitter library talk
 

Similaire à Chemir Analytical Services

Web site content (1).pptx
Web site content (1).pptxWeb site content (1).pptx
Web site content (1).pptxPaulDiDonato1
 
Products Liability & the Middle Market
Products Liability & the Middle MarketProducts Liability & the Middle Market
Products Liability & the Middle MarketDPSchneider
 
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
thermo fisher  ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_IIIthermo fisher  ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_IIIfinance40
 
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
thermo fisher  ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_IIIthermo fisher  ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_IIIfinance40
 
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
thermo fisher  ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_IIIthermo fisher  ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_IIIfinance40
 
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_IIIthermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_IIIfinance40
 
Axsource overview Nov 2012
Axsource overview Nov 2012Axsource overview Nov 2012
Axsource overview Nov 2012Navneet Sekhon
 
R&D Partners - Services Brochure
R&D Partners - Services BrochureR&D Partners - Services Brochure
R&D Partners - Services BrochureJeff Tibaldi
 
Gxp Auditing Services 2010
Gxp Auditing Services 2010Gxp Auditing Services 2010
Gxp Auditing Services 2010qcpeichholz
 
Scynexis Fully Integrated Drug Discovery & Development 2011 Overview
Scynexis Fully Integrated Drug Discovery & Development 2011 OverviewScynexis Fully Integrated Drug Discovery & Development 2011 Overview
Scynexis Fully Integrated Drug Discovery & Development 2011 Overviewbrycechaney
 
IDSC Expertise Capabilities Services Short 10 slides V5 Modified for PDF 2014...
IDSC Expertise Capabilities Services Short 10 slides V5 Modified for PDF 2014...IDSC Expertise Capabilities Services Short 10 slides V5 Modified for PDF 2014...
IDSC Expertise Capabilities Services Short 10 slides V5 Modified for PDF 2014...Mark Creswell
 
Medical Device Technology Capabilities in India
Medical Device Technology Capabilities in IndiaMedical Device Technology Capabilities in India
Medical Device Technology Capabilities in IndiaTejas Shah
 
Biovays Discovery Summit Presentation
Biovays Discovery Summit PresentationBiovays Discovery Summit Presentation
Biovays Discovery Summit PresentationIguanaBio Iguana
 
Rd Partners2
Rd Partners2Rd Partners2
Rd Partners2lmccarthy
 

Similaire à Chemir Analytical Services (20)

satish C.V.20.09.2015
satish C.V.20.09.2015satish C.V.20.09.2015
satish C.V.20.09.2015
 
Web site content (1).pptx
Web site content (1).pptxWeb site content (1).pptx
Web site content (1).pptx
 
Products Liability & the Middle Market
Products Liability & the Middle MarketProducts Liability & the Middle Market
Products Liability & the Middle Market
 
Chem Service Inc Pesticide Reference Standards Catalogue
Chem Service Inc Pesticide Reference Standards CatalogueChem Service Inc Pesticide Reference Standards Catalogue
Chem Service Inc Pesticide Reference Standards Catalogue
 
Chem Service Pesticide Reference Standards Catalogue
Chem Service Pesticide Reference Standards CatalogueChem Service Pesticide Reference Standards Catalogue
Chem Service Pesticide Reference Standards Catalogue
 
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
thermo fisher  ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_IIIthermo fisher  ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
 
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
thermo fisher  ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_IIIthermo fisher  ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
 
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
thermo fisher  ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_IIIthermo fisher  ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
 
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_IIIthermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
thermo fisher ED886123-7163-46F5-8387-5F57485F786B_FINAL09SHOW_III
 
Axsource overview Nov 2012
Axsource overview Nov 2012Axsource overview Nov 2012
Axsource overview Nov 2012
 
R&D Partners - Services Brochure
R&D Partners - Services BrochureR&D Partners - Services Brochure
R&D Partners - Services Brochure
 
Gxp Auditing Services 2010
Gxp Auditing Services 2010Gxp Auditing Services 2010
Gxp Auditing Services 2010
 
Scynexis Fully Integrated Drug Discovery & Development 2011 Overview
Scynexis Fully Integrated Drug Discovery & Development 2011 OverviewScynexis Fully Integrated Drug Discovery & Development 2011 Overview
Scynexis Fully Integrated Drug Discovery & Development 2011 Overview
 
IDSC Expertise Capabilities Services Short 10 slides V5 Modified for PDF 2014...
IDSC Expertise Capabilities Services Short 10 slides V5 Modified for PDF 2014...IDSC Expertise Capabilities Services Short 10 slides V5 Modified for PDF 2014...
IDSC Expertise Capabilities Services Short 10 slides V5 Modified for PDF 2014...
 
Medical Device Technology Capabilities in India
Medical Device Technology Capabilities in IndiaMedical Device Technology Capabilities in India
Medical Device Technology Capabilities in India
 
Doruksistem short presentation
Doruksistem short presentationDoruksistem short presentation
Doruksistem short presentation
 
Biovays Discovery Summit Presentation
Biovays Discovery Summit PresentationBiovays Discovery Summit Presentation
Biovays Discovery Summit Presentation
 
Rd Partners2
Rd Partners2Rd Partners2
Rd Partners2
 
Doruksistem Presentation
Doruksistem PresentationDoruksistem Presentation
Doruksistem Presentation
 
Dnal 1
Dnal 1Dnal 1
Dnal 1
 

Chemir Analytical Services

  • 1. cGMP/GLP COMPLIANT • ISO 9001 CERTIFIED • FDA REGISTERED • DEA LICENSED Analytical Services Analytical Services Analytical Services Deformulation Materials Identification Failure Analysis Litigation Support Consulting S C I E N T I F I C S O L U T I O N S W I T H PA S S I O N A N D P U R P O S E
  • 2. WHAT’S YOUR CHEMICAL CHALLENGE? For over 50 years Chemir Analytical Services has been defining problems, developing solutions and producing reliable, meaningful results for nearly 7000 clients worldwide.
  • 3. Analytical Services Our independent non-routine analytical laboratory solves challenging problems for such industries as food Analytical Services and beverage, pharmaceutical, medical device, personal care, polymers, plastics, packaging, coatings and more. Analytical Services OUR MISSION We strive to maintain the highest degree of scientific excellence, state-of-the-art instrumentation, quality standards and customer service. ANALYTICAL SERVICES ................................2 - Deformulation - Materials Identification TA B L E O F C O N T E N T S SCIENTIFIC EXCELLENCE - Contaminant Identification Our team of scientists designs and implements - Failure Analysis investigations that result in accurate, - Industrial and Consumer Product Testing reliable data with meaningful interpretations. - Polymer Analysis - Emergency Services STATE-OF-THE-ART INSTRUMENTATION Our instrumentation is maintained and calibrated SOLUTIONS FOR INDUSTRY ........................6 regularly to ensure reliable results. - Food and Beverage - Home, Health and Beauty FOCUS ON QUALITY - Pharmaceutical Our facility is ISO 9001 certified, FDA registered - Medical Device and cGMP/GLP compliant. Our quality mission - Plastics and Composites is to achieve total customer satisfaction by delivering on-time, accurate analyses that meet - Packaging each customer’s needs. - Coatings, Adhesives and Sealants - Working Together CUSTOMER SERVICE LITIGATION SUPPORT Our scientists ask the right questions, listen to our clients, and provide practical solutions. Results are AND CONSULTING ................................... 10 provided in a timeframe consistent with customer - Litigation Support requirements, including rush turnaround if needed. - Consulting Services Resources ........................................ 12 Customers ....................................... 14 Case Studies ................................... 16 Terms and Conditions ....................... 17 1
  • 4. Chemir scientists take a customized approach to chemical identification, deformulation and materials testing, utilizing A N A L Y T I C A L a wide variety of techniques and instrumentation. S E R V I C E S DEFORMULATION Unlike other deformulation providers, Chemir’s deliverable is a complete table of ingredients, including Deformulating products and materials is our specialty. quantities and percentages of components. After Also known as reverse engineering, deformulation contacting our clients to discuss the results, we provide is the separation, identification and quantitation of analysis and interpretations in a concise, bound final ingredients in a formulation. report containing a summary, conclusions and any original data. We have successfully deformulated a variety of products such as: - Drug products including oral, topical and liquid dosages Deformulation analysis of commercial products is provided - Personal care products including topical gels, for informational purposes only. Chemir Analytical lotions, creams and ointments - Detergents and cleansers Services strongly recommends review of state and federal - Coatings - Adhesives (PSA, hot melt and water borne) and laws, trademarks, copyrights and patent situations by the sealants (Epoxy, PU, silicone) customer prior to use of such information. - Rubber products (natural rubber, EPDM, TPE, Neoprene, SIS, SBS, NBR, EVA, PUR, silicone and more) - Plastics (PP, PE, PMMA, Nylon, PU, flexible and MATERIALS IDENTIFICATION rigid PVC, copolymer and blends, degradable PP Materials identification can be used to determine the and PE) components of an unknown material, confirm the - Specialty products (multiple layer films, high identity of a suspect material, or to identify differences temperature engineered products) in similar materials. - Composites (glass reinforced, carbon or graphite filled, Kevlar fiber reinforced and more) An unknown material is often the underlying cause of many difficult problems. The goal of material Our clients often come to us with a knowledge of the identification is to understand the chemistry of the types of ingredients in their target formula, such as major components. Chemir has developed expertise the wetting agent, co-solvent or surfactant. Using the in identifying and characterizing unknowns through client’s information along with our scientific expertise, analytical techniques and accurate interpretations. we can create a working “recipe” that meets a variety of needs including: We tackle organic material identification using FTIR - Competitive product characterization spectroscopy to determine the chemical family and - Identification of batch to batch variations functional groups through library matching and - Comparative analysis of “good” and “bad” samples fundamental spectral interpretation. We can also - Patent infringement litigation identify the inorganic components using an SEM equipped with an EDXA elemental analysis technique. Our experienced chemists are kept up-to-date with the latest methods and have developed techniques for Once the data is collected, our experienced scientists unraveling complicated formulations. interpret the information. They are skilled at effectively communicating information to our clients and providing useful results regarding the unknown material. 2 CHEMIR ANALYTICAL SERVICES • 1.800.659.7659 • WWW.CHEMIR.COM
  • 5. Deformulation - Materials Identification - Contaminant Identification - CONTAMINANT IDENTIFICATION When an unknown material is found in a product, manufacturers need to know the source of contamination. Contaminant identification projects involve the determination of components at low concentrations such as ppm or even ppb levels. A strategic technical approach is required to identify the unknown contaminant by using a comparison study between a control and suspect sample. The technical approach is dependent on the sample matrix and the suspected level of contamination. Often, we start with a general screen of the control and suspect samples using GC/MS and LC/MS. Depending on the results, we may need to isolate the contaminant from a large amount of sample to allow for analysis using FTIR and NMR spectroscopy. Once identification is complete, we can further quantify the contaminant in the sample matrix. Typical contaminant identification projects have involved off-odor/flavor investigations, off-color problems, or foreign particles in a product. Some sources of contaminants have been from the environment, improper storage of the product, or poor quality raw materials. We work closely with our clients to trace the source of contamination and develop a corrective action program. 3
  • 6. Our independent laboratory and expert scientists design A N A L Y T I C A L experiments that provide answers to industrial challenges. S E R V I C E S FAILURE ANALYSIS INDUSTRIAL AND CONSUMER PRODUCT TESTING From consumer goods to industrial machinery, the scientists at Chemir Analytical Services can meet your We provide customized product testing for individual failure analysis testing needs. We will help you define components as well as finished manufactured products. the problem and recommend solutions. A product We can investigate advertised product claims as well failure may include premature breakage, discoloration as conduct performance comparisons. Other product or even an unexpected odor. testing includes durability and resistance testing, as well as corrosion, chemical solvent resistance, stain and burn We can help with new or ongoing failures. A sample of resistance, flammability, and fire properties. the “good” vs. “bad” product is often sent to our lab for comparison, but onsite investigations of processes may The effects of the environment can have significant also be necessary. impact on the lifetime and functionality of your product. Chemir can simulate environmental Products tested include packaging, plastics, adhesives, conditions in order to understand the effect on metals, coatings, composites, laminates and more. your product’s performance. Chemir’s final report includes conclusions, results Testing services include: and all the original technical data acquired during the - Degradation analysis including photographs, chromatograms and - Product lifetime spectra. Our years of experience investigating material - Product resistance and product failures allow us to recognize the indicators - Weathering controlled accelerated exposure of failure and follow these leads to their root cause. Chemir has developed, validated and transferred methods for the analysis of inorganic materials. These include metals, sulfates, phosphates, chlorides, fluorides and other anions. When unforeseen quality Materials tested include automotive parts, engines, fabrics, plastic components, toys, sporting goods issues occur, Chemir can help. and appliances. 4 CHEMIR ANALYTICAL SERVICES • 1.800.659.7659 • WWW.CHEMIR.COM
  • 7. Failure Analysis - Industrial and Consumer Product Testing - Polymer Analysis - Emergency Services - POLYMER ANALYSIS EMERGENCY SERVICES When problems arise with the development, production When unforeseen quality issues occur, Chemir can help. or function of polymer based products, Chemir has the Our scientists are available 24/7 to solve complex, non- tools and experience to help. We have investigated a routine problems using a customized approach. wide range of polymeric materials including: - Thermoplastics Whether it is identifying the source of an off-odor - Thermosets or resolving a product failure, Chemir has a - Elastomers solid reputation for delivering results during - High-performance polymers emergency situations. - Specialty polymers - Composites Our analytical investigations provide quick and reliable - Polyurethanes answers needed to manage a crisis. - Adhesives and sealants Depending on our clients’ needs, we can offer a strategic combination of physical and chemical testing to answer specific questions. Physical properties analyzed have included: - Tensile properties - Adhesive strength - Compressibility - Cross-sectional multiple layer film thickness - Melt Flow Index - Thermal properties (including glass transition, melting point, thermal expansion and crystallinity) Our chemical testing capabilities range from obtaining basic information to more detailed and structurally specific results such as: - Chemical family, including base polymer characterization - Molecular weight distribution - End group analysis - Co-polymer backbone chemistry, comonomer contents/ratios, polymer blends - Additive analysis 5
  • 8. Our scientists investigate challenges with products S O L U T I O N S that impact health and well-being. F O R I N D U S T R Y FOOD AND BEVERAGE HOME, HEALTH AND BEAUTY Chemir Analytical Services has helped hundreds of Chemir has helped companies with challenging issues food and beverage manufacturers with challenging food in the personal care, cosmetic, fragrance, soap and testing issues including: detergent industries. We provide custom formulation, - Contaminant identification including ingredient stability studies and pilot-scale, semi-commercial cross-contamination manufacturing. - Off-colors, off-flavors, or off-odors analysis - Packaging trouble-shooting From concept to finished product, our formulation - Extractables and leachables testing scientists help manufacturers create new products or - Foreign object identification improve existing ones. Our staff has years of experience - Emergency response working with a diversity of matrices. Unlike other - Hazard analysis contract facilities, our clients retain the option to full - Toxicity risk assessment rights of their final product formulation. In addition, our experts provide litigation support for We also partner with personal care product food product liability issues and other legal challenges. entrepreneurs, developers and marketing firms to take their ideas from concept to commercialization. Examples of ways we have helped food manufacturers: - Identified diet soda product contamination Chemir Analytical Services has assisted companies in - Determined the cause of bursting potato chip bags the health and beauty industry by providing: - Analyzed levels of benzene in a beverage - Deformulation and reformulation of a - Off-odor source identification in produce discontinued product - Performed contaminant identification in an - Formulation development and pilot batch imported food product production of a mouthwash - Assisted poultry and meat processors with toxicity - Investigation into an off-color nail polish risk assessment - Characterization of an unknown substance in a cosmetic product - Quantification of ingredients in a soap formulation 6 CHEMIR ANALYTICAL SERVICES • 1.800.659.7659 • WWW.CHEMIR.COM
  • 9. Food and Beverage - Home, Health and Beauty - Pharmaceutical - Medical Device - PHARMACEUTICAL When medical device issues involve litigation support, Chemir’s scientists are available to review data, provide Our services to the pharmaceutical industry are focused independent testing and offer expert witness services. on solving difficult problems. Chemir scientists are experienced at designing and performing investigative Examples of problems solved for the medical projects involving contamination or product failure device industry: issues. Our expertise in deformulation and polymer - Analysis of polymeric materials to evaluate analysis has provided many companies with solutions products for resin composition to troubling product challenges. - Investigation of product failure of a polyurethane catheter Chemir also offers analysis and expert witness services - Deformulation of a detector strip in support for cases involving pharmaceutical patent infringement. of an intellectual property case Our chemists are experienced in the courtroom and are - Polymer analysis to investigate biodegradation skilled in explaining technical methods and results in of an implanted device clear and understandable terms. Examples of pharmaceutical challenges Chemir scientists have resolved include: Our facility is cGMP compliant, FDA registered - Determination of the cause of black speck contaminants in aspirin and DEA licensed, and is centrally located in - Deformulation of an OTC product for a St. Louis, Missouri. generic drug manufacturer - Investigation into an off-color of a liquid pharmaceutical product - Litigation support for a patent infringement case involving active pharmaceutical ingredients MEDICAL DEVICE Chemir Analytical Services investigates medical device materials and performance issues involving polymers, plastics, metals, organics, inorganics and more. Our scientists have solved difficult problems with a wide variety of device products including implantables, flexible tubing, containers, protective devices, and more. 7
  • 10. S O L U T I O N S Chemir has been solving tough problems for manufacturers for over 50 years. F O R I N D U S T R Y PLASTICS & COMPOSITES PACKAGING Chemir offers a complete range of analyses for plastics Packaging systems can pose challenging problems and composites. These materials can be found in a wide for manufacturers. We solve complex problems with variety of industries including automotive, sporting cartons, cans, bottles, pouches, vials, bags and more. goods, toys, industrial products, construction materials, We have helped manufacturers in the research and consumer goods and more. Our scientists have development phases as well as trouble-shooting addressed issues such as: finished products. - Premature breakage of a plastic tubing - Failure analysis of a cracking door Our comprehensive instrumentation, wide range - Deformulation of a competitor’s multi-layered of capabilities and extensive experience enable us film product to test a package and also analyze its contents, labels, - Identification of the source of odor in a adhesives, closures, resins, pigments, additives, children’s toy shrink film and more. - Characterization of an unknown contaminant in a polyurethane product Some examples of our problem solving capabilities include: - Determination of the cause of “ballooning” of a sealed pouch packaging system - Identification of the source of delamination of a multi-layered product package - Identification of the composition of a film that developed on a bottle after hot product filling - Deformulation of ink on a package label - Finding the cause of pinhole formation in bags - Comparison of two adhesive products to demonstrate a difference in the applied glues - Isolation of an unusual odor from a package - Testing of competing package sealing systems in a patent infringement case - Determination of the cause of adhesive failure occurring under high temperatures We have helped manufacturers in the research and development phases as well as trouble- shooting finished products. 8 CHEMIR ANALYTICAL SERVICES • 1.800.659.7659 • WWW.CHEMIR.COM
  • 11. Plastics and Composites - Packaging - Coatings, Adhesives and Sealants - Working Together - COATINGS, ADHESIVES AND SEALANTS CEOs/Presidents: Company leaders are most concerned with risk, both financial and legal. Chemir Our scientists investigate a wide variety of issues for has worked with corporate executives faced with patent the coating industry. We have helped manufacturers, disputes, customer complaints, product liability cases, distributors, importers and retailers with customized safety concerns and more. chemical analysis for: - Paints and coatings Production Managers: When production lines are - Adhesives and sealants shut down or mechanical equipment malfunctions, - Inks and dyes managers need reliable answers. Chemir Analytical - Other industrial chemicals Services can perform investigations to determine the root cause of failures, avoiding costly delays and Chemir has helped companies with deformulation resuming operations. and reformulation of coatings products, as well as trouble-shooting difficult challenges. We can also assist Entrepreneurs/Research & Development: Chemir with formulation projects, from bench scale up to helps entrepreneurs accomplish their dreams. Our staff toll production. can develop an idea for a new product from bench- WORKING TOGETHER top to semi-commercial production. We have assisted R&D departments research ingredients, determine Our goal is to become an extension of your research, procedures and make necessary adjustments to match product development or quality control team. Clients the customer’s idea. come to Chemir from a broad spectrum of industries and job functions. A PARTNERSHIP When you call our facility you are connected with a Quality Assurance/Quality Control: Questions from Director of Technical Services, an experienced scientist QA/QC professionals often stem from unforeseen who will ask the right questions, listen and develop quality issues such as contamination, poor product investigations to solve your problem. We are proud performance or premature failure. Our scientists can of our warm and personal service. Our scientific staff help QA/QC develop and evaluate methods for provides regular updates to our clients throughout the a proactive quality program, as well as investigate course of the project. Working as a partnership, we unusual hard-to-solve problems. can recommend changes in materials, reformulation or manufacturing processes. 9
  • 12. Complex problems may require outside experts. Chemir can provide testing L I T I G A T I O N S U P P O R T A N D and testimony in legal cases, as well as consulting on challenging issues. C O N S U L T I N G LITIGATION SUPPORT SERVICES Our chemists have helped resolve issues in intellectual property disputes. As patent expert witnesses, our When challenges involve litigation, our scientists can scientists have offered testimony in patent infringement help. With experts in many disciplines and industries, disputes and trade secret litigation. we provide the technical and professional expertise necessary to support legal challenges. Ph.D. chemists Chemir’s materials scientists have also offered will design independent investigations, supervise forensic chemical and litigation support in product laboratory analyses and write comprehensive reports. liability defense cases, insurance claims and product They are skilled in explaining technical methods and failure litigation. results in clear and understandable terms. Some examples of litigation support projects: Litigation support services include: - Resolved a coatings patent infringement issue by - Evaluation of cases deformulation - Method development and testing - Resolved insurance claims for fire damages through - Interpretation of technical data analysis of explosives and fuels - Critical review of data - Expert consulting for chemical spill at a large - Literature searches company - Trial preparation - Performed failure analysis in a case involving - Depositions and trial testimony premature plastic pipe breakage - Reviewed opposing data in a personal injury lawsuit - Determined the root cause of failure for a window manufacturer in a product liability case - Conducted flame testing on a consumer product to support a client’s personal injury claim With experts in many disciplines and industries, we provide the technical and professional expertise necessary to support legal challenges. 10 CHEMIR ANALYTICAL SERVICES • 1.800.659.7659 • WWW.CHEMIR.COM
  • 13. Litigation Support Services - Consulting Services - CONSULTING SERVICES Whether it is at your facility, here in our laboratories, part of a conference call, or by written report, Chemir’s staff is available for consultation on a variety of projects. Our independent consultants bring new perspectives and experiences valuable for problem solving and product improvement such as: - Defining a manufacturing problem - Working with your staff in problem solving - Recommending different testing procedures or methods - Defining research or quality protocols - Providing expertise in product or process development - Investigating a cause of product failure Our consultants regularly participate in conferences and panels in order to keep up with the latest technical developments in their field and are regarded as leaders in their respective industries. Our consulting experience includes: - Chemical analysis and techniques - Polymers including deformulations, synthesis, additives, alloys, blends and formulations - Consumer products - Fine organic chemicals - Polyolefins, nylons, multilayer films - Advanced composites, carbon fibers - Manufacturing processes 11
  • 14. Our experienced staff of high level scientists, rigorous quality systems and extensive instrumentation enables us to provide industry leading O U R quality and service. R E S O U R C E S PEOPLE - Quality assurance coordinators to work closely with management and technical staff in reviewing Our staff of Ph.D-level chemists, along with advanced analyses for compliance with standards degreed scientists, collaborate to offer creative solutions - Quality team meetings to provide a forum for to non-routine problems. They bring practical industrial addressing questions and concerns on quality issues knowledge, as well as advanced academic credentials to each project. Ensuring Reliable Results: Our quality system is focused on obtaining accurate results. FACILITY - The use of Standard Operating Procedures (SOPs) to ensure uniformity in routine operations Our centrally located facility in Maryland Heights, - Installation, Operation and Performance MO, a suburb of St. Louis, has more than 20,000 sq. Qualification (IQ/OQ/PQ) of analytical ft. of laboratory space equipped with state-of-the-art instrumentation for applicable regulatory work instrumentation. - The use of standard or validated methods for analyses when available QUALITY - Continuing surveillance of published guidance documents to ensure adherence to current regulatory Chemir Analytical Services maintains a Quality policies that impact our clients Management System based on ISO 9001:2000 as well as other certifications. Error Free Reporting: The quality of our reported data is critical. Our quality system, documented procedures and - Documenting all facets of analysis analytical methods reflect our quality policy statement: - Communicating any questionable or non- To achieve total customer satisfaction by delivering on- conformance results to the customer within 24 hours time, accurate analyses that meet each customer’s needs. - Following procedures and complying with standards - Auditing data internally when regulatory compliance The primary goals of our quality program are is required continuous improvement, reliable results and on-time, error free reporting. Our facility is: Continual Improvement: We strive to improve - ISO 9001:2000 Certified our processes, methods and procedures by the - FDA Registered following means: - cGMP/GLP Compliant - Ongoing training programs to help us keep abreast - DEA Licensed of new technologies, regulations and industry trends and to improve our processes 12 CHEMIR ANALYTICAL SERVICES • 1.800.659.7659 • WWW.CHEMIR.COM
  • 15. People - Facility - Quality - Equipment - EQUIPMENT ATOMIC SPECTROSCOPY Inductively Coupled Plasma/Optical Emission Our clients can be assured their samples will be Spectroscopy (ICP/OES) investigated using state-of-the-art instrumentation in Flame Atomic Emission Spectroscopy (Flame AES) the areas of chromatography, spectroscopy, microscopy Cold Vapor Atomic Absorption (CVAA) and polymer testing. New equipment and regular upgrades reflect Chemir’s commitment to customized MICROSCOPY AND SURFACE ANALYSIS solutions and scientific excellence. Optical Microscopy Scanning Electron Microscopy/Energy SEPARATIONS Dispersive X-ray Analysis (SEM/EDXA) Gas Chromatography (GC) Fourier Transform Infrared (FTIR) Sample Introduction Techniques - Microscopy - Direct Liquid Injection - Horizontal Attenuated Total Reflectance - Static Headspace (HATR) - Solid Phase Microextraction (SPME) Raman Microscopy - Purge and Trap - Pyrolysis PHYSICAL AND THERMAL TESTING Detection Systems Instron 1122/1125 - Flame Ionization Detection (FID) Melt Flow Index - Thermal Conductivity Detection (TCD) Thermogravimetric Analysis (TGA) - Mass Spectrometry (MS) Differential Scanning Calorimetry (DSC) Liquid Chromatography (LC) Modulated DSC (MDSC) Detection Systems Dynamic Mechanical Analysis (DMA) - Spectrophotometric (UV-Vis) - Refractive Index (RI) WET CHEMICAL TECHNIQUES AND - Evaporative Light Scattering (ELSD) OTHER EQUIPMENT - Electrospray Ionization-Ion Trap Mass Karl Fischer Volumetric Titration Spectrometry (ESI-IT-MS) pH - Atmospheric Pressure Chemical Ionization- Ion Selective Electrodes (ISE) Ion Trap Mass Spectrometry (APCI-IT-MS) Soxhlet Extraction Gel Permeation Chromatography (GPC) Accelerated Solvent Extraction Ion Chromatography (IC) Glass Capillary Viscometers Brookfield Viscometers MOLECULAR SPECTROSCOPY Weathering Chambers Ultraviolet-Visible Spectrophotometry (UV-Vis) Zeta Potential Fourier Transform Infrared Spectroscopy (FTIR) Stability Chambers Raman Spectroscopy Nuclear Magnetic Resonance Spectroscopy (NMR) Additionally, we have access to unique - Proton 400 MHz instrumentation at local universities and affiliate - Carbon 400 MHz facilities. When needed, we partner with outside - Multi Nuclear, 19F, 29Si, 31P, 15N, etc. laboratories that have successfully passed our rigorous - Variable Temperature Capabilities quality approval process. - 2D NMR (COSY, NOESY, HMQC, HMBC, TOCSY, HSQC) 13
  • 16. O U R Chemir has helped over 7,000 customers worldwide since 1959. C U S T O M E R S PARTIAL CLIENT LIST - Dowell Schlumberger, Inc. - Dupont - 3M Corporation - Duracell, Inc. - ACH Food Companies - Eaton Corporation - Akin Gump Strauss Hauer & Feld LLP - Emerson Electric - AKZO Nobel-Fortafil Fibers, Inc. - Exxon Chemical Company - Alpha Plastics, Inc. - FedEx - Anheuser-Busch Companies - FMC Corporation - Archbald & Spray LLP - GE Plastics - Ashland Chemical - GenCorp Polymer Products - BASF Corporation - General Polymers - BF Goodrich Company - Georgia-Pacific Corporation - Borg-Warner Automotive - Gillette Company - Bostik, Inc. - Graphic Packaging International, Inc. - BP Chemicals, Inc. - Gulf States Asphalt Co., Inc. - Calgon Vestal Laboratories - HB Fuller Company - Cargill, Inc. - Holland & Knight LLP - Chevron Chemical - Jones & Granger - Colorite Plastics Company - Jones Day - Cozen O’Connor - Latham & Watkins LLP - Da/Pro Rubber Inc. - MacDermid, Inc. - Dow Chemical Company - Mattel Toys, Inc. - MEMC Electronic Materials, Inc. - Monsanto - Morton International - Owens-Corning - Perkin-Elmer - Pillsbury Company - PQ Corporation - Pratt & Whitney - Ralston Purina Company - Rubbermaid Commercial Products - Sonnenschein Nath & Rosenthal - Therm-O-Disc, Inc. - Ultradent Products, Incorporated - United States Army Research Lab - Valspar Corporation - Velcro - W.R. Grace & Company - Zoltek Corporation 14 CHEMIR ANALYTICAL SERVICES • 1.800.659.7659 • WWW.CHEMIR.COM
  • 17. Partial Client List - What Customers Say About Chemir - WHAT CUSTOMERS SAY ABOUT CHEMIR “Excellent follow-up. After analysis was complete, they called me to discuss findings. Good personal touch.” “Responsive, timely and good service.” Mark Magnussen, International Paper, Shelbyville, IL Kaj Johnson, Method, San Francisco, CA “Everything was professionally handled. The analysis “Great customer and technical service staff. Very was impressive” knowledgeable and friendly. Enjoyed collaborating with Robert C. Naylor, Jr., Pierre Foods, Cincinnati, OH all Chemir staff.” Marco Hobi, Devro Inc., Columbia, SC “Communication was excellent. It was never a problem to get an update or an explanation. The testing was “Answers! Several techniques used to get them. Good done in a timely manner, as well as the final report.” reports. Thoroughness in analysis.” Beth Gramza, Beiersdorf, Inc., Cincinnati, OH Dr. Carolyn M. Primus, Primus Consulting, Bradenton, FL “Timely, professional, satisfying and informative” Randy Allen, Temple Inland, “Exceptional service. Results delivered promptly Humboldt Industrial Park, PA and always on or before the promised date...very professional and a pleasure to work with.” Dr. Vikram Mehrotra, Monsanto, St. Louis, MO “The staff was very helpful and the communication was great.” Burk Lattimore, Meadow Gold Dairies, “Exceptional service. Las Vegas, NV Results delivered promptly “Friendly service, well-organized reports, quality results, overall great experience.” and always on or before the promised date.” Robert Sorenson, Ultradent Products, South Jordan, UT “Customer service. The quality of work was outstanding!” Timothy Jackson, Jr., FedEx, Memphis, TN 15
  • 18. C A S E Recent success stories illustrate Chemir’s experience and capabilities. S T U D I E S LEACHING FOOD PACKAGING LITIGATION SUPPORT FOR A MANUFACTURER A frozen food manufacturer came to Chemir to In a lawsuit against a glass-laminate manufacturer, determine if their “in-the-bag-cooking” packaging was an installation contractor claimed that an incorrect contaminating the food during microwave cooking. product formulation was the cause of product failure. Our expert scientists first analyzed the packaging and The glass-polyester laminates had experienced serious then the microwaved food samples. Two components discoloration, degradation, delamination and from the packaging were found to migrate into the food hydrolysis. Our expert chemists performed a tested. One served as a flame retardant and the second comparative analysis of a failed sample alongside a as a plasticizer. We then helped the client find a new control sample. From the data, our scientists concluded packaging source that did not exhibit leaching, allowing that the manufacturer used an incompatible UV them to resume production. stabilizer along with an unstable polymer formulation. Chemir scientists presented this data and interpretations HEAT SEAL ADHESIVE FAILURE ANALYSIS as expert witness testimony for the installation contractor, resulting in a positive outcome for our client. Our client’s new heat seal adhesive was not providing a hermetic seal and released after only a few days. Faced EMERGENCY CONTAMINANT ANALYSIS with production line shut-down and delayed shipments, the customer called Chemir. They suspected that the Chemir’s 24 hour emergency phone number was called new adhesive’s formula, a polyurethane-acrylic hot melt on a Sunday afternoon. The door to a meat processing adhesive, was the reason for the failure. Our expert plant was left open while a pesticide was being sprayed, chemists deformulated both the old formula and the and they needed to determine if the product was new formula. The results showed significant differences contaminated. Results were needed by the following in the molecular weight and molecular weight morning, as 2000 butchers were holding operations. distribution, as well as the urethane-acrylic ratio. After extracting the meat using a proprietary solvent, After concluding that these variations were the reason Chemir used GC/MS to screen the extracts, looking for the adhesion failure, we recommended a formula for the 3 main components of the pesticide. None were adjustment. The revised formula performed well, and observed. We also intentionally spiked samples of meat the customer was able to resume operations. with pesticide, confirming the effectiveness of the test methods. The processor was able to resume operations on Monday morning. MEDICAL PLASTIC STABILITY A manufacturer of an implantable medical device needed to characterize several different polymers in order to identify the materials’ chemical changes over time. The manufacturer needed to know that the device would remain stable and effective inside patient’s bodies. Chemir’s scientists performed GPC analysis comparing the molecular weight of the polymers under various conditions, and were able to recommend an appropriate material selection. 16 CHEMIR ANALYTICAL SERVICES • 1.800.659.7659 • WWW.CHEMIR.COM
  • 19. 9. Chemir reserves the right to subcontract Services to COSTS AND PAYMENT other laboratories. If subcontracting is necessary, samples will be sent only to laboratories meeting 1. Client agrees to pay all invoices within 15 days of T E R M S A N D Chemir’s qualification requirements. invoice date. 2. In the event that payment is not received within 15 C O N D I T I O N S LIABILITY days of invoice date, Client agrees to pay a late payment charge on the unpaid balance equal to 1. Chemir is not an insurer or a guarantor. Chemir 1-1/2% per month. represents that the Services shall be performed 3. All costs associated with compliance with any SERVICES within the limits mutually agreed to, in writing, and subpoena(s) for documents, testimony in court of law, in a manner consistent with the level of care and skill or for any other purpose relating to Services performed 1. Client acknowledges that Chemir Analytical Services, ordinarily exercised by providers of similar services by Chemir for Client, shall be paid by Client. Client Inc. and/or its affiliates (together, “Chemir”) performs under similar circumstances. No other representations shall also pay Chemir’s then existing standard fees analysis and testing services (the “Services”) only as or warranties, express or implied, are included or for consulting, deposition and trial testimony and all specified in writing by Client. Chemir does not design, intended in this agreement, or in any report, opinion or expenses related thereto. warrant, supervise or monitor compliance of products or document related to the Services provided hereunder. 4. Project specific supplies including, but not limited to, services except as specifically agreed to in writing prior 2. For the safety of Chemir’s personnel, Client must advise standards, raw materials, shipping, columns and/or to the performance of the Services. Client acknowledges Chemir if samples are known or suspected to contain specialty chemicals and supplies required for execution that, by their very nature, the Services are limited in hazardous substances. Material Safety Data Sheets of a Client’s project will be purchased by Chemir and scope and subject to expected measurement variability. must be provided if available. billed to Client as pass-through costs. If necessary, 2. Samples and portions thereof not destroyed in the 3. Client understands and agrees that Chemir, in entering Chemir may bill a waste disposal fee of up to 5% of performance of the Services remain the property of the into this Contract and by performing Services, does not total project cost or $500.00, whichever is lower, to Client, are retained a maximum of 30 days after project assume, abridge, abrogate or undertake to discharge cover proper sample and chemical disposal. completion, unless instructed otherwise in writing by any duty or responsibility of Client to any other party or 5. Chemir reserves the right to request a prepayment from Client, and thereafter will be disposed of or returned parties. No one other than Client shall have any right Client prior to initiating project work. to Client, at Client’s expense. A sample storage fee of to rely on any report issued by Chemir. Client agrees, 6. Should Client cancel all or a portion of the project after $200.00 per month will be applied on requests for in consideration of Chemir undertaking to perform the project has been initiated, Client will be liable to storage past 30 days after project completion. the Services hereunder, to protect, defend, indemnify, Chemir for all hours expended on the project up to the 3. Unless otherwise specified therein in writing, nothing save harmless and exonerate Chemir from any and time of cancellation, at a rate of $385.00 per hour, plus contained in any report issued by Chemir shall be all claims, damages, including lost profits, expenses, all project specific supplies at cost, or a minimum of deemed to imply or mean that Chemir conducts any including attorney’s fees, either direct or consequential, 25% of the estimated project cost as a fee for Chemir’s quality control program for the Client to whom the for any and all injuries to persons, including the mobilization on the project, whichever is greater. This report is issued. personnel of Chemir, or property arising out of or in cancellation charge is a fee for work performed and is 4. Reports issued by Chemir are for the exclusive use of consequence of the performance of the Services and/or not regarded as liquidated damages. the Client to whom they are addressed. Reports and the performance of the samples tested hereunder. the name Chemir, or its seals or insignias, are not to be 4. Client agrees that if Chemir should be found liable for MISCELLANEOUS used by or on behalf of Client under any circumstances any losses or damages attributable to the Services in for any purpose whatsoever, including but not limited 1. This agreement and any and all claims and disputes any respect, Chemir’s liability shall in no event exceed to use in advertising, publicity material or in any other hereunder or related thereto shall be governed by the the amount of the fee paid by Client for such Services manner without Chemir’s prior written approval. internal laws of the State of Missouri. Chemir and Client and Client’s sole remedy at law or in equity shall be the 5. Reports issued by Chemir apply only to the standards agree that exclusive jurisdiction and venue for any right to recover up to such amount. Client acknowledges or procedures identified therein and to the sample(s) and all such claims and disputes shall be in St. Louis and agrees that in no event will Chemir be liable for tested. County, Missouri. consequential or incidental damages or expenses, 6. Chemir shall retain copies of reports for a period of five 2. In the event that Chemir prevails in any dispute including, but not limited to lost profits. years, after which such reports will be destroyed. or claim, including the collection of monies from 5. Whenever performance by either party is delayed or 7. Unless specified in a report in writing, the analysis and Client, Client agrees that Client will pay any and all prevented by war, insurrection, fire or other casualty, testing results are not indicative or representative of the expenses, including collection costs and attorney’s fees, strikes or embargoes, shortage of transportation qualities of the lot from which the sample was taken or reasonably incurred in the prosecution or defense of facilities or any other similar or dissimilar causes, of apparently identical or similar products. such claim, dispute or collection. beyond the control of such party, such delay 8. Deformulation analysis of commercial products is 3. The terms and conditions contained herein, together or prevention shall be excused and the time of provided for informational purposes only. Chemir with Chemir’s quotation and offer of Services to Client, performance hereunder extended for the duration strongly recommends review of state and federal laws, and Client’s acceptance of such offer, shall constitute of the causative factor. trademarks, copyrights and patent situations by the the entire agreement between Chemir and Client. Any Client prior to use of such information. conflicting terms contained in any order or acceptance submitted by Client shall be null and void. Analytical Services Analytical Services
  • 20. Analytical Services 2672 Metro Blvd M a r y l a n d H e i g h t sA n a Oy t i3 0 4 3S e r v i c e s , M l 6 cal toll-free 800.659.7659 tel 314.291.6620 fax 314.291.6630 Analytical Services e m a i l i n f o @ c h e m i r. c o m w e b w w w. c h e m i r. c o m