Embedding mechanisms for data reuse and reproducibility in bioscience
1. Embedding
underpinning
mechanisms
for
data
reuse
and
reproducibility
in
bioscience
The
ISA
Exemplar
(Inves=ga=on/Study/Assay)
-‐behind
the
PDF-‐
Alejandra
González-‐Beltrán,
PhD
Oxford
e-‐Research
Centre,
University
of
Oxford,
UK
Beyond
the
PDF
2,
Amsterdam,
Netherlands,
March
20th
2013
2. Source
of
the
figure:
EBI
website
Bioscience
Mul=ple
domains
Mul=ple
communi=es
Mul=ple
technologies
Mul=ple
data
types
Mul=ple
data
formats
Mul=ple
data
repositories
…
Community
engagement
ISA
infrastructure
Generic
format
for
Open
source
rich
experimental
soVware
tools
descrip=ons
3. Minimise
the
burden
and
provide
tools
and
incen=ves
for
repor=ng,
cura=ng,
sharing
data
and
metadata
of
bioscience
experiments
to
enable
the
comprehension,
re-‐use
of
data
in
subsequent
inves=ga=ons
and
reproducibility
of
bioscience
8. Experimental
descrip=on
provenance/aZribu=on
tracking
aggrega=on:
workflow
publica=ons,
data
samples
characteris=cs
community
standards
experimental
design
+
sta=s=cal
ontology
methods
annota=ons
…
cura=on
at
source
incremental
across
the
research
cycle
(from
planning/grant
wri=ng
up
to
manuscripts
publica=on
and
beyond)
9. collaborate
query
visualize
store
filter
share
create
analyse
curate
submit
research
objects
nanopub
share
query
integrate
link
infer