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STRABISMUS
•   Visual axis ; line of vision ; extending from the point of fixation to the fovea
•   Strabismus ; misalignment of the visual axes
•   orthophoria ; perfect alignment of the visual axes. Most individuals have
    heterophoria
•   Heterophoria ; (latent squint) tendency of the eyes to deviate. Ocular
    alignment maintained with effort.
•   Heterotropia; (manifest squint) which is present at all times
•   Esophoria; latent squint inwards turning of the eyes
•   Esotropia; manifest squint inwards turning of the eyes
•   Exophoria; latent squint outwards turning of the eyes
•   Exotropia; manifest squint outwards turning of the eyes
•   Hyperphoria/hypertropia; latent/manifest squint upwards turning of eyes
•   Hypophoria/hypertropia; latent/manifest squint downwards turning of eyes
•   Anatomical axis ; is a line passing from the posterior pole through the centre
    of the cornia .
•   Angle kappa is the angle subtended by the visual and anatomical axes .
Extraocular muscles
•   Horizontal muscles;
     –   Medial rectus-; Its sole action in the primary position is adduction. occulomotor nerve supply
     –   Lateral rectus- Its sole action in the primary position is abduction.; abducens nerve supply
•   Vertical muscles;
     –   Superior rectus- Primary action elevation (secondary actions are adduction and intorsion.
         Oculomotor r nerve supply
     –   Inferior rectus ; The primary action is depression ; secondary actions are adduction and
         extortion. oculomotor nerve supply
•   Oblique muscles;
     –   Superior oblque; Originates superomedial to the optic foramen. It passes forwards through
         the trochlea at the angle between the srperior and medial walls and is then reflected
         backwards and laterally to insert in the posterior upper temporal quadrant of the globe.The
         primary action is intorsion ;secondary actions are depression and abduction.
     –    oculomotor nerve supply
     –   Inferior oblique; Orginates from a small depression just behind the orbital rim lateral to the
         lacrimal sac. It passes backwards and laterally. To insert in the posterior lower temporal
         quadrant of the globe, close to the macula. The prmary action is extorsion;;secondary action
         are elevation and abduction . oculomotor nerve supply
• Listing plane is an imaginary coronal plane passing
    through the centre of rotation of the globe. The globe
    rotates on the X,Y and Z axes of Fick., which intersect in
    Listing plane .
•   The globe rotates left and right on the vertical Z axis.
•   The globe moves up and down on the horizontal X axis.
•   Torsional movements (wheel rotations) occur on the Y
    (sagittal ) axis which traverses the globe form front to
    back (similar to the anatomical axis of the eye )
•   Intorsion occurs when the superior limbus rotates nasally
    and extorsion on temporal rotation .
• OCULAR MOVEMENTS
• Ductions
  – Ductions are monocular movements around the axes of Fick. They consist of
    adduction,abduction elevation, depression, intosion and extorrsion . They are
    tested by occluding the fellow eye and asking the patient to follow a target in
    each direction of gaze.
  Versions
  – Versions are binocular, simultaneous, conjugate movements ( in the same
    directon ) .
  – Dextroversion and laevoversion elevation and depression .These four
    movements bring the globe into the secondary positions of gaze by rotation
    around either a vertical or a horizontal X axis of Fick.
  – Dextroelevation and dextrodepression and laevoelevation and laevodepression .
    These four oblique movements bring the eyes into the tertairy positions of gaze
    by rotation around oblique axes in listing plane, equivalent to simultaneous
    movement about both the horizontal and vertical axes.
  – Torsional movements which maintain upright images occur on tilting of the head.
• VERGENCES
• Vergences are binocular, simultaneous disjugate
  or disjunctive movements .Convergence is
  simultaneous adduction; divergence is outwards
  movement from a convergent position.
  Convergence may be voluntary or reflex. Reflex
  convergence has four components:
  –   Tonic
  –   Proximal
  –   Fusional
  –   Accommodative
• Positions of gaze
• Six Cardinal positions of gaze are those in which
  one muscle in each eye has to move the eye
  into that position as follows:
  – Dextroversion
  – Laevoversion
  – Dextroelevation
  – Laevoelevation
  – Dextrodepression
  – Laevodepression
  Nine Diagnostic position of gaze are those in
    which deviations are measured. They
    consists of the six cardinal postions ,the
    primary position, elevation and depression .
Laws of ocular motility
• Agonist ; antagonist – muscles of the same eye moving
    the eye in opposite direction; medial and lateral rectus
•   Synergists= muscles of the same eye moving it in the
    same direction; superior rectus and inferior oblique
    causing elevation
•   Yoke muscles= muscles of both eyes moving the eyes in
    same direction; medial rectus of both eyes
•   Sherrington law; increase in innervation to one muscle
    causes decreased innervation to its antagonist; medial
    and lateral rectus
•   Hering law; equal innervation flows to yoke muscles in
    eye movement ; medial rectus of both eyes
Consequences of squint
Suppression , amblyopia , confusion and diplopia , postural
   changes according to strabismus
1. Amblyopia
   – Definition – unilateral or bilateral decrease of best corrected
     visual acuity caused by stimulus deprivation or abnormal
     interaction for which there is no pathology of the eye or the
     visual pathway
   – Types
       • Strabismic amblyopia; abnormal interaction
       • Stimulus deprivation amblyopia ; form vision deprivation
       • Anisometropic amblyopia; difference of refractive errors in both eye ;
           one eye is amblyopic
       •   Ametropic amblyopia; form vision deprivation of both eyes
       •   Meridional amblyopia; because of astigmatism
Diagnosis

• 1. visual acuity; difference of two lines in
  best corrected visual acuity in the absence
  of organic lesion
• 2. neutral density filter; normal eyes have
  visual acuity reduced by two lines but
  there is no change in amblyopia
treatment

• Sensitive period during which the
  amblyopia can be cured is below 10 years
  of age
• 1. occlusion of the normal eye to
  encourage the use of the abnormal eye is
  the most effective treatment
• 2. penalization; of the normal eye ; blurring
  of the vision with atropine
EXAMINATION
EXAMINATION

 History:
 A careful history is important in the diagnosis of
     strabismus
 A.   Family History
 B.   Age at Onset
 C.   Type of Onset
 D.   Type of Deviation
 E.   Fixation
EXAMINATION

• Visual Acuity

• Determination of Refractive Error

• Inspection
EXAMINATION

• Determination of Angle of Deviation (Angle of
  Deviation)
  a. Prism and Cover Tests
     1. Cover tests
     2. Uncover tests
     3. Alternate cover tests
     4. Prism plus cover testing
  b. Objective tests
     1. Hirschberg method
     2. Prism reflex method (Krimsky test)
EXAMINATION

• Ductions (Monocular Rotations)
• Versions (Conjugate Ocular Movements)
• Disjunctive Movements
  – Convergence
  – Divergence
EXAMINATION

• Sensory Examination
  – Stereopsis testing

  – Suppression testing
Classification of Esotropia
• 1. Accommodative
  – a Refractive
     Fully accommodative
    Partially accommodative
  – b Non-refractive
     With convergence excess
     With accommodation weakness
  – c Mixed
2.Non- accommodative
– Essential infantile
– Microtropia
– Basic
– Convergence
– Convergence spasm
– Divergecne insufficiency
– Divergecne Paralysis
– Sensory
– Consecutive
– Acute onset
– Cyclic
• Classification of Exotropia

Constant (early onset ) exotropia
Intermittent exotropia
Sensory exotropia
Consecutive exotropia
Objective and Principles of Therapy
           of Strabismus
Objective and Principles of Therapy of
Strabismus

• Reversal of the deleterious sensory effects
 of strabismus (amblyopia, suppression
 and loss of stereoposis)

• Best possible alignment of the eyes by
 medical or surgical treatment
Objective and Principles of Therapy of
Strabismus

• Timing of treatment on children
Medical Treatment
• Treatment of Amblyopia
  – Occlusion therapy
     • Initial stage
     • Maintenance stage
  – Atropine therapy
• Optical Devices
  – Spectacles
  – Prisms
• Botulinum Toxin
• Orthoptics
Surgical Treatment

• Surgical procedures
  – Resection and recession
  – Shifting of point of muscle attachment
  – Faden procedure
• Choice of muscles for surgery
• Adjustable sutures

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Strabismus

  • 2. Visual axis ; line of vision ; extending from the point of fixation to the fovea • Strabismus ; misalignment of the visual axes • orthophoria ; perfect alignment of the visual axes. Most individuals have heterophoria • Heterophoria ; (latent squint) tendency of the eyes to deviate. Ocular alignment maintained with effort. • Heterotropia; (manifest squint) which is present at all times • Esophoria; latent squint inwards turning of the eyes • Esotropia; manifest squint inwards turning of the eyes • Exophoria; latent squint outwards turning of the eyes • Exotropia; manifest squint outwards turning of the eyes • Hyperphoria/hypertropia; latent/manifest squint upwards turning of eyes • Hypophoria/hypertropia; latent/manifest squint downwards turning of eyes • Anatomical axis ; is a line passing from the posterior pole through the centre of the cornia . • Angle kappa is the angle subtended by the visual and anatomical axes .
  • 3. Extraocular muscles • Horizontal muscles; – Medial rectus-; Its sole action in the primary position is adduction. occulomotor nerve supply – Lateral rectus- Its sole action in the primary position is abduction.; abducens nerve supply • Vertical muscles; – Superior rectus- Primary action elevation (secondary actions are adduction and intorsion. Oculomotor r nerve supply – Inferior rectus ; The primary action is depression ; secondary actions are adduction and extortion. oculomotor nerve supply • Oblique muscles; – Superior oblque; Originates superomedial to the optic foramen. It passes forwards through the trochlea at the angle between the srperior and medial walls and is then reflected backwards and laterally to insert in the posterior upper temporal quadrant of the globe.The primary action is intorsion ;secondary actions are depression and abduction. – oculomotor nerve supply – Inferior oblique; Orginates from a small depression just behind the orbital rim lateral to the lacrimal sac. It passes backwards and laterally. To insert in the posterior lower temporal quadrant of the globe, close to the macula. The prmary action is extorsion;;secondary action are elevation and abduction . oculomotor nerve supply
  • 4.
  • 5.
  • 6.
  • 7.
  • 8. • Listing plane is an imaginary coronal plane passing through the centre of rotation of the globe. The globe rotates on the X,Y and Z axes of Fick., which intersect in Listing plane . • The globe rotates left and right on the vertical Z axis. • The globe moves up and down on the horizontal X axis. • Torsional movements (wheel rotations) occur on the Y (sagittal ) axis which traverses the globe form front to back (similar to the anatomical axis of the eye ) • Intorsion occurs when the superior limbus rotates nasally and extorsion on temporal rotation .
  • 9. • OCULAR MOVEMENTS • Ductions – Ductions are monocular movements around the axes of Fick. They consist of adduction,abduction elevation, depression, intosion and extorrsion . They are tested by occluding the fellow eye and asking the patient to follow a target in each direction of gaze. Versions – Versions are binocular, simultaneous, conjugate movements ( in the same directon ) . – Dextroversion and laevoversion elevation and depression .These four movements bring the globe into the secondary positions of gaze by rotation around either a vertical or a horizontal X axis of Fick. – Dextroelevation and dextrodepression and laevoelevation and laevodepression . These four oblique movements bring the eyes into the tertairy positions of gaze by rotation around oblique axes in listing plane, equivalent to simultaneous movement about both the horizontal and vertical axes. – Torsional movements which maintain upright images occur on tilting of the head.
  • 10.
  • 11. • VERGENCES • Vergences are binocular, simultaneous disjugate or disjunctive movements .Convergence is simultaneous adduction; divergence is outwards movement from a convergent position. Convergence may be voluntary or reflex. Reflex convergence has four components: – Tonic – Proximal – Fusional – Accommodative
  • 12.
  • 13. • Positions of gaze • Six Cardinal positions of gaze are those in which one muscle in each eye has to move the eye into that position as follows: – Dextroversion – Laevoversion – Dextroelevation – Laevoelevation – Dextrodepression – Laevodepression Nine Diagnostic position of gaze are those in which deviations are measured. They consists of the six cardinal postions ,the primary position, elevation and depression .
  • 14.
  • 15. Laws of ocular motility • Agonist ; antagonist – muscles of the same eye moving the eye in opposite direction; medial and lateral rectus • Synergists= muscles of the same eye moving it in the same direction; superior rectus and inferior oblique causing elevation • Yoke muscles= muscles of both eyes moving the eyes in same direction; medial rectus of both eyes • Sherrington law; increase in innervation to one muscle causes decreased innervation to its antagonist; medial and lateral rectus • Hering law; equal innervation flows to yoke muscles in eye movement ; medial rectus of both eyes
  • 16.
  • 17.
  • 18. Consequences of squint Suppression , amblyopia , confusion and diplopia , postural changes according to strabismus 1. Amblyopia – Definition – unilateral or bilateral decrease of best corrected visual acuity caused by stimulus deprivation or abnormal interaction for which there is no pathology of the eye or the visual pathway – Types • Strabismic amblyopia; abnormal interaction • Stimulus deprivation amblyopia ; form vision deprivation • Anisometropic amblyopia; difference of refractive errors in both eye ; one eye is amblyopic • Ametropic amblyopia; form vision deprivation of both eyes • Meridional amblyopia; because of astigmatism
  • 19. Diagnosis • 1. visual acuity; difference of two lines in best corrected visual acuity in the absence of organic lesion • 2. neutral density filter; normal eyes have visual acuity reduced by two lines but there is no change in amblyopia
  • 20. treatment • Sensitive period during which the amblyopia can be cured is below 10 years of age • 1. occlusion of the normal eye to encourage the use of the abnormal eye is the most effective treatment • 2. penalization; of the normal eye ; blurring of the vision with atropine
  • 22. EXAMINATION History: A careful history is important in the diagnosis of strabismus A. Family History B. Age at Onset C. Type of Onset D. Type of Deviation E. Fixation
  • 23. EXAMINATION • Visual Acuity • Determination of Refractive Error • Inspection
  • 24.
  • 25.
  • 26.
  • 27. EXAMINATION • Determination of Angle of Deviation (Angle of Deviation) a. Prism and Cover Tests 1. Cover tests 2. Uncover tests 3. Alternate cover tests 4. Prism plus cover testing b. Objective tests 1. Hirschberg method 2. Prism reflex method (Krimsky test)
  • 28.
  • 29. EXAMINATION • Ductions (Monocular Rotations) • Versions (Conjugate Ocular Movements) • Disjunctive Movements – Convergence – Divergence
  • 30.
  • 31.
  • 32. EXAMINATION • Sensory Examination – Stereopsis testing – Suppression testing
  • 33.
  • 34.
  • 35.
  • 36. Classification of Esotropia • 1. Accommodative – a Refractive Fully accommodative Partially accommodative – b Non-refractive With convergence excess With accommodation weakness – c Mixed
  • 37. 2.Non- accommodative – Essential infantile – Microtropia – Basic – Convergence – Convergence spasm – Divergecne insufficiency – Divergecne Paralysis – Sensory – Consecutive – Acute onset – Cyclic
  • 38. • Classification of Exotropia Constant (early onset ) exotropia Intermittent exotropia Sensory exotropia Consecutive exotropia
  • 39.
  • 40.
  • 41. Objective and Principles of Therapy of Strabismus
  • 42. Objective and Principles of Therapy of Strabismus • Reversal of the deleterious sensory effects of strabismus (amblyopia, suppression and loss of stereoposis) • Best possible alignment of the eyes by medical or surgical treatment
  • 43. Objective and Principles of Therapy of Strabismus • Timing of treatment on children
  • 44. Medical Treatment • Treatment of Amblyopia – Occlusion therapy • Initial stage • Maintenance stage – Atropine therapy • Optical Devices – Spectacles – Prisms • Botulinum Toxin • Orthoptics
  • 45. Surgical Treatment • Surgical procedures – Resection and recession – Shifting of point of muscle attachment – Faden procedure • Choice of muscles for surgery • Adjustable sutures