2. Cytological features of malignancy
Lesion : Remarkable variation in cell size and shape (Cellular
polymorphism )and nuclear size and shape (nuclear polymorphism )
mitotic figures (M) and nuclear hyperchromatism.

3. • Cytological features of malignancy
• Necrosis (N) of the tumor related to ischaemia.

4. • Organ: myometrium
• Lesion: benign neoplasm of the uterine smooth
muscle (L) surrounded by normal myometrium.
• Diagnosis: Leiomyoma .

5. • Organ: myometrium ( higher magnification)
• Lesion: tumor margin well circumscribed and
no evidence of local invasion and their is
pseudocapsule (C).

6. • organ: Breast
• Lesion: the neoplasm has an irregular outline and the
neoplastic cells invading the fatty tissue and
collagenous stroma of the breast.
• Diagnosis: malignant neoplasm of Breast.

7. • organ: Breast ( higher magnification)
• Lesion: hyperchromatic malignant cells can be
seen infiltrating the surrounding adipose tissue.
• Diagnosis: malignant neoplasm of Breast.

8. • Lesion: the cells are commonly arranged in broad
sheets and large nests (N) , formation of keratin*
known as dyskeratosis (D), and forms lamellated
pink-stained masses known as keratin pearls (KP).
• Squamous cell Carcinoma.

9. • Organ: Colon
• Lesion: mitosis are seen and nuclear hyperchromatism
and higher nuclear to cytoplasmic ratio.
• Diagnosis: Adenocarcinoma ( well Differentiated )

10. • Organ: Connective tissue
• Lesion: Consist of various combination of spindle cells
(S) ,cells resembling histiocytes (H) with pale foamy
cytoplasm and malignant giant cells (G) mitotic figures are
plentiful.
• Diagnosis: Malignant Fibrous Histiocytoma.

11. Pathology: the Hidden Science that SavesPathology: the Hidden Science that Saves
LivesLives
Pathology: is the Science behind the CurePathology: is the Science behind the Cure
 This pathology lab is prepared by, Dr. Omar EmadThis pathology lab is prepared by, Dr. Omar Emad
Ibrahim , Pathology Dep. Faculty of Medicine &Ibrahim , Pathology Dep. Faculty of Medicine &
Health Sciences, Thamar UniversityHealth Sciences, Thamar University ..
 The images is taken fromThe images is taken from
Atlas of Basic Histopathology.