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Dr. Awadhesh Sharma Study of Microvascular & Macrovascular Complications  in Prediabetics (Impaired Glucose Tolerance)” Department of Medicine MLB Medical College, Jhansi
What is pre-diabetes? Pre-diabetes is a condition where blood sugar levels are higher than normal, but not yet high enough to be diagnosed as diabetes. Pre-diabetes is a key factor in the development of type 2 diabetes. However, n ot  everyone with pre-diabetes goes on to develop type 2 diabetes. Pre-diabetes is characterized by disturbance in blood sugar levels as measured by impaired glucose tolerance (IGT) or impaired fasting glucose (IFG). Patients can have one or both of these conditions to be considered pre-diabetic.
 
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Diagnosis Criteria   ,[object Object],[object Object],*  FBG blood test is done after fasting 8 hours. ** GTT results are repeated after 2 hours. A person drinks a 75 mg glucose solution before test. 100 mg for Pregnant women. Normal Pre diabetes Diabetes Fasting Blood Glucose Test (FBG)* Less than 100 Between  100 - 125 More than or equal to  126 Glucose Tolerance Test (GTT) ** Less than 140 Equal to or more than  140  but less than  200 More than or equal to  200
Why We Worry About Prediabetes? ,[object Object],[object Object],[object Object]
Risk of Cardiovascular Disease Is Elevated Prior to Diagnosis of T2DM % with CVD *MI=myocardial infarction. Adapted from: Hu F, et al.  Diabetes Care.  2002;25:1129-1134.
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Symptoms of Prediabetes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Risk Factors for the Development of S Prediabetes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
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Body Mass Index (BMI)   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],Waist Circumference (WC)   It is a simple measurement at waist level
Sedentary Lifestyles   ,[object Object],[object Object]
Increase of Lipids (Fats) in the Blood ,[object Object],[object Object],[object Object],[object Object],Lipids Normal Values Total Cholesterol Less than  200  mg/dl ,[object Object],Less than  100  mg/dl ,[object Object],Men:  Higher than  45  mg/dl  Women: Higher than  55  mg/dl  Triglycerides Less than  150  mg/dl
High Blood Pressure ,[object Object],[object Object]
Our Study
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Material & Methods   The study entitled  “ Study of Microvascular & Macrovascular Complications in Prediabetics (Impaired Glucose Tolerance) ”  was conducted in the department of Medicine of M.L.B. Medical College, Jhansi from the period of June 2006 to September 2009. The cases were patients coming to Medicine OPD and in the emergency being admitted in the Medicine ward as cases of impaired glucose tolerance or prediabetes. Fifty patients of prediabetes were included in the study which are selected from Medicine OPD and those who admitted in the Medicine ward.
 
 
 
 
 
 
 
 
 
 
 
 
 
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How we manage ?
Health Physical Activity + Sound Nutrition Good Health
Health The first part of our equation is activity Get moving, find something you enjoy
Health The second part of the equation is nutrition   Your body needs the right fuel to help it work well.
How Can You Help   Reduce   Your Risk of Diabetes? Eat foods low in  fat & calories. If overweight, lose weight.    Physical activity Stop smoking! Limit alcohol to 1-2 drinks per day. Take your  medications regularly.
Encourage people to change habits . Use the pyramid guide to educate people to eat healthy.
Is drug therapy useful in patients with pre-diabetes? Drug therapy is not recommended by the ADA due to the limited efficacy of treatment versus lifestyle modification, potential for adverse drug reactions, lack of data supporting reduction of microvascular or macrovascular complications of diabetes in this patient population, and insufficient assessment of the cost-effectiveness of drug treatment. However, not all patients are able to implement lifestyle modifications due to physical or other  limitations, and based on limited data available, drug therapy may be a reasonable option to delay onset of type 2 diabetes and provide a cardiovascular benefit (TRIPOD and STOP-NIDDM data).
THANK YOU

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Prediabetes Awadhesh Med

  • 1. Dr. Awadhesh Sharma Study of Microvascular & Macrovascular Complications in Prediabetics (Impaired Glucose Tolerance)” Department of Medicine MLB Medical College, Jhansi
  • 2. What is pre-diabetes? Pre-diabetes is a condition where blood sugar levels are higher than normal, but not yet high enough to be diagnosed as diabetes. Pre-diabetes is a key factor in the development of type 2 diabetes. However, n ot everyone with pre-diabetes goes on to develop type 2 diabetes. Pre-diabetes is characterized by disturbance in blood sugar levels as measured by impaired glucose tolerance (IGT) or impaired fasting glucose (IFG). Patients can have one or both of these conditions to be considered pre-diabetic.
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  • 7. Risk of Cardiovascular Disease Is Elevated Prior to Diagnosis of T2DM % with CVD *MI=myocardial infarction. Adapted from: Hu F, et al. Diabetes Care. 2002;25:1129-1134.
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  • 20. Material & Methods The study entitled “ Study of Microvascular & Macrovascular Complications in Prediabetics (Impaired Glucose Tolerance) ” was conducted in the department of Medicine of M.L.B. Medical College, Jhansi from the period of June 2006 to September 2009. The cases were patients coming to Medicine OPD and in the emergency being admitted in the Medicine ward as cases of impaired glucose tolerance or prediabetes. Fifty patients of prediabetes were included in the study which are selected from Medicine OPD and those who admitted in the Medicine ward.
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  • 36. Health Physical Activity + Sound Nutrition Good Health
  • 37. Health The first part of our equation is activity Get moving, find something you enjoy
  • 38. Health The second part of the equation is nutrition Your body needs the right fuel to help it work well.
  • 39. How Can You Help Reduce Your Risk of Diabetes? Eat foods low in fat & calories. If overweight, lose weight.  Physical activity Stop smoking! Limit alcohol to 1-2 drinks per day. Take your medications regularly.
  • 40. Encourage people to change habits . Use the pyramid guide to educate people to eat healthy.
  • 41. Is drug therapy useful in patients with pre-diabetes? Drug therapy is not recommended by the ADA due to the limited efficacy of treatment versus lifestyle modification, potential for adverse drug reactions, lack of data supporting reduction of microvascular or macrovascular complications of diabetes in this patient population, and insufficient assessment of the cost-effectiveness of drug treatment. However, not all patients are able to implement lifestyle modifications due to physical or other limitations, and based on limited data available, drug therapy may be a reasonable option to delay onset of type 2 diabetes and provide a cardiovascular benefit (TRIPOD and STOP-NIDDM data).