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Introduction to
Biotechnology
Biotechnology
Biotechnology helps to
 meet our basic needs.
Food, clothing, shelter,
 health and safety
Biotechnology
Improvements by using
 science
Science helps in
 production plants, animals
 and other organisms
Biotechnology
Also used in
 maintaining a good
 environment that
 promotes our well
 being
Biotechnology
Using scientific processes
 to get new organisms or
 new products from
 organisms.
Biotechnology
Large area
Includes many
 approaches and methods
 in science and technology
Office of Tech
Assessment Definition
Any technique that uses
 living organisms or
 substances from those
 organisms to make or modify
 a product, to improve plants
 or animals….
Cont.
Or to develop
 microorganisms for
 specific uses.
Agricultural View
All of the applied science
 based operations in
 producing food, fiber,
 shelter, and related
 products
Agricultural View
Milk production
New horticultural and
 ornamental plants
Wildlife, aquaculture, natural
 resources and environmental
 management
Multidisciplinary
Involves many disciplines
 or branches of learning
Includes all areas of Life
 Sciences
Organismic Biotech
Working with complete,
 intact organisms or their cells
Organisms are not
 genetically changed with
 artificial means
Organismic Biotech
Help the organism live better
 or be more productive
Goal – improve organisms
 and the conditions in which
 they grow
Organismic Biotech
Study and use natural
 genetic variations
Cloning is an example of
 organismic biotech
Cloning
Process of producing a new
 organism from cells or
 tissues of existing organism.
1997 cloned sheep – “Dolly”
 in Edinburgh Scotland
Molecular Biotech
Changing the genetic
 make-up of an organism
Altering the structure and
 parts of cells
Complex!
Molecular Biotech
Uses genetic engineering,
 molecular mapping and
 similar processes
Genetic
Engineering
Changing the genetic
 information in a cell
Specific trait of one organism
 may be isolated,cut, and
 moved into the cell of
 another organism
Transgenic
Results of Gen. Eng. Are
 said to be “transgenic”
Genetic material in an
 organism has been altered
Biotech examples
 Medicine
 Agriculture
 Environment
 Forestry
 Food and beverage
 processing
Medicine
 Some new developments
 delve into the hereditary
 material of humans known
 as gene therapy
Medicine
 Therapeutant - product used to
  maintain health or prevent
  disease
 Biopharmaceuticals – drug or
  vaccine developed through
  biotechnology
 Called designer drugs
Medicine
 Biopharming – production of
  pharmaceuticals in cultured
  organisms
 Combination of the
  agriculture and
  pharmaceutical industries
Medicine
 Certain blood – derived
 products needed in human
 medicine can be produced
 in the milk of goats
Environment
 Any biotechnological process
  that may promote a good
  environment
 Organisms developed during
  the gulf war to “eat” oil
 Organism used in gold mining
  to “eat” contaminants
Environmental
 Problems naturally solved
 by microorganisms such
 as bacteria, fungi break
 down contaminant into a
 form less harmful or not
 harmful
Ag and Forestry
 Plant biotech
 Animal biotech
Plant biotech
 Improve plants and the
  products produced from them
 Insect and disease resistance
 Engineered to have desired
  characteristics
Plant biotech
 Corn plant produced with
 high levels of the amino
 acid Lysine
Animal Biotech
 Improve animals or the
  products they produce
 Animals may be used to
  produce products that
  promote human health
Animal Biotech
 Increase productivity
 Pigs engineered to
 produce human
 hemoglobin
Food and
Beverages
 Use of technology in
  producing and processing
 Some biotech principles
  have been employed for
  hundreds of years
 Yeast in baking bread
Food and Bev.
 Genetically altered crops
 rBGH milk
Biotechnology
 Helps meet human needs
 Food, clothing and shelter
 Plants and animals are used
 in manufacturing food,
 clothing and materials for
 shelter
Biotechnology
 Used to make products
  more useful or desirable
 Ex: conversion of milk into
  cheese or yogurt
Efficiency
 Must keep the cost of
  improving products as low
  as possible
 Biotech results in greater
  efficiency
Efficiency
 Inoculating legume seeds
  with bacteria that allow the
  plant to pull nitrogen out of
  the air and put it into the soil
 Saves the producer the cost
  of applying N fertilizer
Efficiency
 Results in trees that grow
 faster and produce wood
 that is more desirable
Greater Production
 Increases yields
 bST use in cows to produce
  more milk
 Higher crop yields from
  drought, disease & insect
  resistant crops
Health Promoting
Foods
 Food with unique traits
 Some contain
  therapeutants
 Some designed with
  nutrient enrichment
Safety
 Consumers want foods to
  provide needed nutrients and
  in some cases, enhanced
  foods
 Do not want side effects from
  those enhanced foods
Easy preparation
 Flavr-Savr Tomato
 Reached the market in
  early 1990’s
 Engineered to have a
  longer shelf life
Flavr-Savr
 No soft spots
 No rotten spots
 Tomato resists spoilage
Synthetic biology
 Creating lifelike
  characteristics through the
  use of chemicals
 Based on creating structures
  similar to those found in
  living organisms
Synthetic Biology
 Need for synthetic cells lead
  to the development of the
  vesicle
 Vesicle – tiny rounded
  structure with cell like traits
Vesicle
 Tiny structures similar to
  soap bubbles were created
  to serve as the cell
  membrane
 Visible only with powerful
  microscope
Vesicle
 Once the cell membrane
 has been successfully
 developed, development
 of the materials with the
 cell is initiated.
Synthetic biology
 Is important because it
  brings science closer to
  creating life in the lab
 Cells and tissues may be
  developed to treat human
  injury and disease
introduction to biotechnology

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