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Kingdom of Saudi
Arabia
 King Fahd Hospital
       Jeddah
   Internal Medical
     Department
Dengue Fever
By:
        Dr.wail Bajhmoum

   Wednesday 21/5/2008 ; 16/5/1429
Background

Frequency

Race ; Sex and Age
Transmission

Mortality/Morbidity

Clinical Presentation
Treatment

Our hospital statistic
Background

Dengue fever–like illnesses were
described in Chinese medical
writings dating back to 265 AD.

 In 1789, Benjamin Rush, MD,
published an account of a dengue
fever epidemic that had occurred in
Philadelphia in 1780.
The first epidemic of
dengue hemorrhagic fever
was described in Manila in
1953.
Frequency
 Dengue virus causes about 100
  million cases of acute febrile
  disease annually, including more
  than 500,000 reported cases of
  DHF/DSS.

 Currently, dengue is endemic in
 112 countries.
Race ; Age and Sex

Ethnicity is nonspecific

All ages are susceptible.
Both sexes have the same
 incidence, however, fewer
 cases have been reported more
 in men than in women.
Transmission

  o
      by mosquito vectors
      
          Aedes aegypti in the sub-
          tropical and tropical Americas
      
          Aedes albopictus in Asia
Aedes Aegypti the Dengue Vector
Mortality/Morbidity
•
     Treated DHF/DSS is associated
    with a 3% mortality rate.
•
      Untreated DHF/DSS is
    associated with a 50% mortality
    rate.
Clinical Presentation
 Rash– petechial, diffuse
 erythematous or
 morbilliform

 Hemorrhagic  manifestations
 – epistaxis, petechiae, gum
 bleeding
 Leukopenia

 Thrombocytopenia

 Lymphadenopathy
 Breakbone   fever

 Infectioncan lead to DHF,
 resulting in renal failure and
 DSS
Treatment

No vaccine available, treatment
 is supportive
Our hospital statistic
Range of Patie nts Age



                   21 - 34 Year
Patient




          10               30            50
                                  Year
% Male Vs. %Female
           Patients


27%




                       73%
Positive IgM
           Vs.
    Nigative Patients


Negative
   IgM
Patients,
  28%


                    Positive
                       IgM
                    Patients,
                      72%
% Saudi Vs . Non Saudi
         w ith
     Pos itive IgM




 Non               Saudi
Saudi               49%
 51%
4 Months Patients
            Vs.
       Total Patients




11


                         60
%Male Vs. %Female
            with
        PositiveIgM




Fe m ale
  33%


                     M ale
                     67%
Thank you

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