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Chapter 4 – Cellular Metabolism Cellular metabolism enables the organism to grow.
You are responsible for the following figures and tables : Fig. 4.14 - metabolic processes, anabolic and catabolic. Fig. 4.1, 4.2, 4.3 – Macromolecules. Fig. 4.4 - control of metabolism is achieved by enzymes. -see table summary in the attached lecture handout - Fig. 4.5  - metabolism occurs complex biochemical pathways. Fig. 4.15 - Metabolic reactions can be regulated by feedback mechanism. Read TB, p.108, on 'cellular respiration'.  Fig. 4.6 - Cellular respiration consists of 3 biochemical pathways.  -see table summaries in the attached lecture handout - -see also Ch.9 regarding ‘oxygen debt’ resulting in the synthesis of lactate instead of pyruvate- Fig. 4.17, 4.18 - RNA and DNA.  Fig. 4.24 – DNA.  Fig. 4.22 -  transcription – translation Fig. 4.25 - Mutation  Fig. 4.26 - Explain PKU.
Metabolic Processes ,[object Object],[object Object]
Dehydration Synthesis ,[object Object],[object Object],[object Object]
Hydrolysis ,[object Object],[object Object],[object Object],[object Object]
Metabolic Pathways ,[object Object],[object Object]
Metabolic Pathways ,[object Object],[object Object],[object Object]
Metabolism is made possible through the action of Enzymes ,[object Object],[object Object],[object Object],[object Object]
Enzyme Catalyzing a Synthetic Reaction ,[object Object],E  +  S  ES  P Fig. 4.4
Cofactors and Coenzymes ,[object Object],[object Object],[object Object]
Denaturation ,[object Object],[object Object],[object Object]
Release / Storage of Chemical Energy: ATP ,[object Object],[object Object],[object Object],[object Object],[object Object]
Release of Chemical Energy During Cellular Respiration in a Muscle Cell Fig. 4.6
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Adenosine Triphosphate (ATP) ,[object Object],[object Object],Figure 4.7
CELLULAR RESPIRATION  = Need for O 2  and Release of  CO 2  as waste from tissues GLYCOLYSIS CONVERSION STEP CITRIC ACID CYCLE ETC LOCATION cytoplasm mitochondria Mitochondrial matrix mitochondrial inner membrane O 2  Required? NO yes yes yes Starting Product glucose  (6-C) 2 pyruvates (2 x 3C) Acetyl CoA (2 x 2C) 10 NADH 2 FADH 2 End- Products 2 pyruvates (2 x 3-C) 2 -4 ATP 2 NADH 2 Acetyl CoA 2 NADH 2 CO 2 6 NADH 2 FADH 2 2-4 ATP 4 CO 2 30 ATP 2-4 ATP 2-4 ATP TOTAL 34-38 ATP
Glycolysis ,[object Object],[object Object],[object Object],[object Object]
Anaerobic Respiration ,[object Object],[object Object],[object Object],[object Object]
Aerobic Respiration (Fig. 4.12) ,[object Object]
Citric Acid Cycle Cycles Organic Acids ,[object Object],[object Object],[object Object],[object Object],[object Object]
Electron Transport Chain ,[object Object],[object Object],[object Object]
Metabolic Pathways of Carbohydrates ,[object Object],[object Object],Fig. 4.13
[object Object],[object Object],[object Object],[object Object],[object Object],Metabolic Pathways of Carbohydrates
Genetic Information ,[object Object],[object Object],[object Object]
DNA Structure (Figure 4.19) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DNA Replication ,[object Object],[object Object],[object Object],Figure 4.24
DNA Replication ,[object Object],[object Object],[object Object]
Genetic Code ,[object Object],[object Object],[object Object],[object Object]
Transcription (Figure 4.22)
Transcription (Figure 4.22) ,[object Object],[object Object],[object Object]
Transcription ,[object Object],[object Object],[object Object],[object Object],[object Object]
RNA Molecules ,[object Object],Figure 4.20
Protein Synthesis (Translation) ,[object Object],[object Object],[object Object],Figure 4.23
Mutations-Changes in Genetic Information ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 

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Ch4 Ppt Lect 1

  • 1. Chapter 4 – Cellular Metabolism Cellular metabolism enables the organism to grow.
  • 2. You are responsible for the following figures and tables : Fig. 4.14 - metabolic processes, anabolic and catabolic. Fig. 4.1, 4.2, 4.3 – Macromolecules. Fig. 4.4 - control of metabolism is achieved by enzymes. -see table summary in the attached lecture handout - Fig. 4.5 - metabolism occurs complex biochemical pathways. Fig. 4.15 - Metabolic reactions can be regulated by feedback mechanism. Read TB, p.108, on 'cellular respiration'. Fig. 4.6 - Cellular respiration consists of 3 biochemical pathways. -see table summaries in the attached lecture handout - -see also Ch.9 regarding ‘oxygen debt’ resulting in the synthesis of lactate instead of pyruvate- Fig. 4.17, 4.18 - RNA and DNA. Fig. 4.24 – DNA. Fig. 4.22 - transcription – translation Fig. 4.25 - Mutation Fig. 4.26 - Explain PKU.
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  • 13. Release of Chemical Energy During Cellular Respiration in a Muscle Cell Fig. 4.6
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  • 16. CELLULAR RESPIRATION = Need for O 2 and Release of CO 2 as waste from tissues GLYCOLYSIS CONVERSION STEP CITRIC ACID CYCLE ETC LOCATION cytoplasm mitochondria Mitochondrial matrix mitochondrial inner membrane O 2 Required? NO yes yes yes Starting Product glucose (6-C) 2 pyruvates (2 x 3C) Acetyl CoA (2 x 2C) 10 NADH 2 FADH 2 End- Products 2 pyruvates (2 x 3-C) 2 -4 ATP 2 NADH 2 Acetyl CoA 2 NADH 2 CO 2 6 NADH 2 FADH 2 2-4 ATP 4 CO 2 30 ATP 2-4 ATP 2-4 ATP TOTAL 34-38 ATP
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